GO:0005758

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Name mitochondrial intermembrane space
Categary Component
Go Slim No
Go Link GO:0005758
Unique Molecular Interactions 336
Total Molecular Interactions 444
Total Single Events 8085
Pain Genes Associated 25

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mitochondrial intermembrane space. They are ordered first by their pain relevance and then by number of times they were reported for mitochondrial intermembrane space. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54
2 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37
3 INT115443 Regulation of Binding of Cpox and Defb40 1 0.00 1.28 1.76
4 INT115442 Binding of Cpox and Defb40 1 0.00 1.28 1.76
5 INT103592 CAP1 Negative_regulation of Gene_expression of CPOX 1 0.19 1.52 1.64
6 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
7 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
8 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
9 INT190128 Positive_regulation of PTGER1 Negative_regulation of Gene_expression of CPOX 1 0.04 1.21 1.38
10 INT194513 Timp1 Negative_regulation of Cpox 1 0.00 0.9 1.31
11 INT42580 CAT Negative_regulation of POMC 1 0.20 0.42 1.26
12 INT190130 Binding of CPOX and MRXS5 1 0.00 1.4 1.23
13 INT107029 Cpox Regulation of Pag1 1 0.01 1.24 1.15
14 INT117504 OPA1 Positive_regulation of CPP 1 0.09 1.09 1.13
15 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
16 INT56990 Cat Regulation of Efs 1 0.26 0 1.05
17 INT323077 CPOX Negative_regulation of Gene_expression of Ptger2 1 0.00 1.57 1.05
18 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 0.02 0.3 1.02
19 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
20 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
21 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
22 INT303690 KNG1 Positive_regulation of CPOX 1 0.01 0.76 0.96
23 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
24 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89
25 INT75920 Slc8a1 Negative_regulation of Cpox 1 0.03 0.85 0.89
26 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
27 INT115444 Cpox Positive_regulation of Localization of Defb42 1 0.00 0.64 0.87
28 INT271780 Zfp560 Negative_regulation of Cpox 1 0.00 0.62 0.86
29 INT107698 FN1 Positive_regulation of Gene_expression of CPOX 1 0.13 0.26 0.84
30 INT149925 Negative_regulation of Cpox Negative_regulation of Gene_expression of Pde4d 1 0.01 0.39 0.84
31 INT84717 Il1b Regulation of Cpox 1 0.00 0.37 0.83
32 INT352201 Negative_regulation of ALOX5 Negative_regulation of Cpox 1 0.02 0.89 0.81
33 INT84039 EGF Positive_regulation of Gene_expression of CPOX 2 0.11 1.88 0.8
34 INT84040 EGF Positive_regulation of CPOX 2 0.07 1.91 0.8
35 INT140966 NFKB1 Positive_regulation of Positive_regulation of CPOX 1 0.08 0.66 0.8
36 INT168457 Sult1a1 Positive_regulation of Cat 1 0.15 1.56 0.78
37 INT141911 Arih2 Regulation of Positive_regulation of Cpox 1 0.01 1.19 0.76
38 INT141910 Arih2 Regulation of Cpox 1 0.01 1.19 0.76
39 INT107702 DCSTAMP Positive_regulation of Gene_expression of CPOX 1 0.04 0.32 0.75
40 INT119313 Cpox Regulation of Gene_expression of Ptger2 1 0.02 0.6 0.74
41 INT117639 Serpini1 Negative_regulation of Cpox 1 0.00 0.64 0.72
42 INT149983 Binding of Cpox and Nos2 1 0.30 0.54 0.69
43 INT347962 Cpox Negative_regulation of Positive_regulation of Nos1 1 0.02 0.59 0.67
44 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 0.03 0.24 0.65
45 INT105848 Il1b Positive_regulation of Gene_expression of Cpox 1 0.12 0.41 0.59
46 INT270099 Negative_regulation of Binding of CPOX and PLA2G2A 1 0.01 0.51 0.59
47 INT157141 Cpox Positive_regulation of Gene_expression of Camk2a 1 0.19 0.13 0.58
48 INT270103 Binding of CPOX and PLA2G2A 1 0.01 0.5 0.58
49 INT145491 PROC Positive_regulation of Cpox 1 0.00 1.08 0.58
50 INT122313 Nfkb1 Regulation of Gene_expression of Cpox 1 0.00 0.51 0.57
51 INT122314 Nfkb1 Regulation of Cpox 1 0.00 0.51 0.56
52 INT270101 CPOX Negative_regulation of PLA2G2A 1 0.01 0.48 0.56
53 INT122315 Negative_regulation of Nfkb1 Regulation of Cpox 1 0.00 0.51 0.56
54 INT196879 Cpox Negative_regulation of Gene_expression of Tbxa2r 1 0.04 0.8 0.56
55 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
56 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52
57 INT112659 Cpox Positive_regulation of Gene_expression of TNF 1 0.01 0.79 0.52
58 INT112661 Cpox Positive_regulation of Localization of TNF 1 0.01 0.79 0.52
59 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52
60 INT285688 Cpox Positive_regulation of PPARA 1 0.02 1 0.5
61 INT282285 Cpox Regulation of Gene_expression of Ptger2 1 0.00 0.84 0.5
62 INT145435 Binding of CPOX and HMOX1 1 0.01 0.42 0.49
63 INT145433 Binding of CPOX and HMOX2 1 0.01 0.42 0.49
64 INT217760 Il1f5 Positive_regulation of Gene_expression of Cpox 1 0.00 0.27 0.47
65 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47
66 INT217759 Il1f5 Positive_regulation of Cpox 1 0.00 0.27 0.47
67 INT203177 Negative_regulation of CPOX Positive_regulation of Gene_expression of Lts1 1 0.00 0.72 0.46
68 INT131819 Binding of Cpox and Nfkb1 1 0.15 0.44 0.46
69 INT116926 Cpox Regulation of AKR1C3 1 0.01 0.28 0.45
70 INT237452 Binding of STAR and CHTF8 1 0.00 0.48 0.45
71 INT241912 Cat Positive_regulation of Ros1 1 0.03 0.76 0.44
72 INT234599 Cpox Negative_regulation of Gene_expression of Ptgds 1 0.05 0.6 0.44
73 INT314263 Binding of CPOX and PTGES3 1 0.01 1.7 0.44
74 INT234600 Negative_regulation of Cpox Negative_regulation of Gene_expression of Ptgds 1 0.05 0.6 0.44
75 INT237453 Binding of STAR and MESP1 1 0.00 0.47 0.42
76 INT107701 Negative_regulation of FN1 Positive_regulation of CPOX 1 0.11 0.13 0.42
77 INT107696 FN1 Positive_regulation of CPOX 1 0.12 0.13 0.41
78 INT107703 PPARG Regulation of Gene_expression of CPOX 1 0.16 0.15 0.41
79 INT205926 Helt Regulation of Cpox 1 0.01 0 0.41
80 INT156438 Cpox Positive_regulation of Nos2 3 0.14 1.24 0.4
81 INT279414 Binding of CPOX and ACTR1B 1 0.04 1.55 0.4
82 INT121849 CASP8 Positive_regulation of CYCS 1 0.35 0.48 0.4
83 INT237454 Binding of STAR and GREM1 1 0.00 0.44 0.4
84 INT121852 CASP8 Positive_regulation of Localization of CYCS 1 0.32 0.48 0.4
85 INT107706 PPARA Positive_regulation of Gene_expression of CPOX 1 0.18 0.14 0.4
86 INT139047 Negative_regulation of AR Negative_regulation of Positive_regulation of CPOX 1 0.07 0.76 0.4
87 INT107700 Positive_regulation of DCSTAMP Positive_regulation of CPOX 1 0.04 0.14 0.38
88 INT107697 DCSTAMP Positive_regulation of CPOX 1 0.06 0.14 0.38
89 INT354820 Creb1 Negative_regulation of Transcription of Cpox 1 0.03 0.59 0.38
90 INT117184 GOLPH3 Regulation of CXCR4 1 0.30 0.29 0.37
91 INT350814 Negative_regulation of TNF Positive_regulation of Gene_expression of Cpox 1 0.06 1.33 0.37
92 INT235432 Ppara Negative_regulation of Gene_expression of Cpox 1 0.01 1 0.37
93 INT350816 TNF Positive_regulation of Gene_expression of Cpox 1 0.05 1.33 0.37
94 INT117182 GOLPH3 Regulation of Binding of CXCR4 1 0.50 0.29 0.37
95 INT106511 Binding of Cpox and Ptges3 2 0.01 0.7 0.36
96 INT255803 Cat Negative_regulation of Gene_expression of Il6 1 0.05 0.35 0.35
97 INT90388 NFKB1 Positive_regulation of CPOX 1 0.32 0.18 0.35
98 INT176135 AKT1 Regulation of Localization of CYCS 1 0.43 2.16 0.35
99 INT134080 OPA1 Negative_regulation of Phosphorylation of Gnb2l1 1 0.03 0.22 0.34
100 INT134303 Cpox Negative_regulation of PTGS2 1 0.00 0.77 0.34
101 INT134301 Cpox Negative_regulation of Gene_expression of Ptger2 1 0.00 0.77 0.34
102 INT141848 Mthfs Negative_regulation of Cpox 1 0.01 0 0.34
103 INT203166 Negative_regulation of CPOX Positive_regulation of Gene_expression of LTB4R 1 0.00 0.65 0.34
104 INT240434 PPARA Negative_regulation of Gene_expression of CPOX 1 0.03 0.64 0.33
105 INT258173 Negative_regulation of Cpox Negative_regulation of Gene_expression of Gtf3a 1 0.00 1.44 0.33
106 INT99597 Negative_regulation of CPOX Regulation of Negative_regulation of ZNF398 1 0.02 0.44 0.33
107 INT124475 MAP2K1 Positive_regulation of Positive_regulation of CPOX 1 0.04 0.68 0.33
108 INT147984 Ptgds Positive_regulation of Cpox 1 0.17 0.29 0.32
109 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 0.02 0.21 0.32
110 INT124261 Jun Regulation of Gene_expression of Cpox 1 0.13 0.44 0.32
111 INT147982 Cpox Positive_regulation of Gene_expression of Ptgds 1 0.17 0.3 0.32
112 INT194733 Binding of CPOX and HNRNPA0 1 0.01 0.44 0.32
113 INT124258 Creb1 Regulation of Gene_expression of Cpox 1 0.17 0.44 0.32
114 INT75769 Egf Positive_regulation of Cpox 1 0.26 0.76 0.31
115 INT187523 IRF6 Positive_regulation of Gene_expression of Cpox 1 0.00 1.38 0.31
116 INT74940 HGF Positive_regulation of CPOX 1 0.13 0.25 0.3
117 INT203169 CPOX Regulation of Gene_expression of PTGER2 2 0.00 0.48 0.29
118 INT93580 Hgf Positive_regulation of Cpox 1 0.19 2.2 0.29
119 INT203170 Negative_regulation of CPOX Positive_regulation of ALOX5 1 0.01 0.53 0.29
120 INT156439 Positive_regulation of Cpox Positive_regulation of Nos2 1 0.14 0.52 0.28
121 INT156440 Cpox Positive_regulation of NOS1 1 0.01 0.52 0.28
122 INT116592 CPOX Regulation of PTGER2 1 0.02 0.45 0.28
123 INT117202 Binding of GFER and Mefv 1 0.03 2.01 0.28
124 INT116593 CPOX Regulation of IL6 1 0.10 0.45 0.28
125 INT114066 Agtr2 Regulation of Gene_expression of Cpox 1 0.08 0.62 0.27
126 INT241911 Binding of Cat and Ros1 1 0.03 0.85 0.27
127 INT280181 Pde5a Positive_regulation of Regulation of Cpox 1 0.00 0.16 0.26
128 INT195898 Negative_regulation of Egf Negative_regulation of Gene_expression of Cpox 1 0.03 0.3 0.26
129 INT105003 Binding of PDYN and SHMT2 1 0.04 0.49 0.26
130 INT156587 Hst1 Negative_regulation of Gene_expression of Cpox 1 0.15 0.82 0.26
131 INT148629 Binding of Cat and Casp3 1 0.08 0.09 0.26
132 INT102621 IL6 Regulation of Gene_expression of CPOX 1 0.13 0.78 0.25
133 INT114244 Cpox Negative_regulation of Gene_expression of APP 1 0.00 0.7 0.25
134 INT278967 MST1 Regulation of Gene_expression of CPOX 1 0.00 0.41 0.25
135 INT278945 NOS2 Regulation of Gene_expression of CPOX 1 0.02 0.41 0.25
136 INT124078 Binding of Ace and Cpox 1 0.09 0.14 0.24
137 INT110061 Binding of Alox5 and Cpox 1 0.28 0.37 0.23
138 INT139045 Negative_regulation of AR Negative_regulation of CPOX 1 0.07 0.34 0.23
139 INT120583 Gsta4 Regulation of Cat 1 0.03 0 0.23
140 INT328228 Binding of Cpox and Hmox1 1 0.03 0.83 0.23
141 INT143629 CPOX Positive_regulation of Gene_expression of MRXS5 1 0.05 0.55 0.23
142 INT333394 CFD Negative_regulation of Gene_expression of Cat 1 0.03 0.79 0.22
143 INT142446 Regulation of CPOX Regulation of Gene_expression of PTGIS 1 0.10 0.26 0.22
144 INT97472 CPOX Regulation of Gene_expression of MRXS5 1 0.02 0.16 0.21
145 INT334379 Ros1 Regulation of Cat 1 0.04 0.08 0.21
146 INT152748 Negative_regulation of Cpox Negative_regulation of Localization of Tnf 1 0.17 0.98 0.21
147 INT124263 Plat Positive_regulation of Gene_expression of Cpox 1 0.07 0.42 0.21
148 INT172895 Binding of Cpox and Selenbp2 1 0.00 0.64 0.2
149 INT145140 Negative_regulation of CPOX Negative_regulation of Gene_expression of CYP19A1 1 0.13 0.47 0.2
150 INT113809 Negative_regulation of Cpox Negative_regulation of Gene_expression of VEGFA 1 0.02 0.97 0.18
151 INT139877 CPOX Regulation of Gene_expression of PTGES 1 0.17 0.07 0.18
152 INT139881 CPOX Regulation of Transcription of PTGES 1 0.17 0.07 0.18
153 INT240435 JUN Positive_regulation of Gene_expression of CPOX 1 0.01 0.81 0.18
154 INT130932 Negative_regulation of Cpox Positive_regulation of Gene_expression of TSC1 1 0.00 0.42 0.18
155 INT138323 Positive_regulation of CPOX Regulation of PPAP2A 1 0.09 0.18 0.18
156 INT139878 PTGES Regulation of Gene_expression of CPOX 1 0.17 0.07 0.18
157 INT139879 PTGES Regulation of Transcription of CPOX 1 0.17 0.07 0.18
158 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
159 INT207375 Negative_regulation of CPOX Negative_regulation of Gene_expression of Chol1 1 0.10 0.37 0.17
160 INT207348 TBXA2R Negative_regulation of CPOX 1 0.03 0 0.17
161 INT314270 CPOX Negative_regulation of Gene_expression of PTGER2 1 0.01 0.15 0.17
162 INT155232 TXNIP Regulation of BAX 1 0.23 0.15 0.17
163 INT350363 Gatm Negative_regulation of NOS1 1 0.00 0.31 0.17
164 INT117183 Binding of CXCR4 and GOLPH3 1 0.53 0.27 0.16
165 INT354819 Binding of Cpox and Ptgs2 1 0.02 0.45 0.16
166 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
167 INT207253 INS Negative_regulation of TXNIP 1 0.45 1.2 0.15
168 INT248147 PLAT Positive_regulation of Gene_expression of CPOX 1 0.00 0.51 0.15
169 INT241177 Abl2 Regulation of Cat 1 0.14 0.3 0.15
170 INT137647 PYCARD Positive_regulation of NLN 1 0.02 0.08 0.15
171 INT137646 Negative_regulation of PYCARD Positive_regulation of NLN 1 0.02 0.08 0.15
172 INT89597 Binding of CPOX and TBXAS1 1 0.04 0.05 0.14
173 INT114967 ERI1 Negative_regulation of CPOX 1 0.00 0.25 0.14
174 INT173499 EEF1A2 Negative_regulation of Cpox 1 0.07 0.39 0.14
175 INT181752 Binding of CPOX and ESR1 1 0.02 0.89 0.14
176 INT252177 VEGFA Regulation of Gene_expression of CPOX 1 0.03 0.56 0.14
177 INT302676 Binding of OPA1 and MFN2 1 0.46 1.12 0.14
178 INT93579 Positive_regulation of Hgf Positive_regulation of Cpox 1 0.14 1.1 0.14
179 INT130922 HMHA1 Positive_regulation of Protein_catabolism of CYCS 1 0.06 1.39 0.14
180 INT130917 HMHA1 Positive_regulation of CYCS 1 0.06 1.39 0.14
181 INT207352 ZNF398 Regulation of CPOX 1 0.00 0 0.14
182 INT207347 PTGER1 Negative_regulation of CPOX 1 0.00 0 0.14
183 INT141001 Negative_regulation of CPOX Regulation of Localization of INS 1 0.17 0.07 0.14
184 INT207341 PTGER2 Negative_regulation of CPOX 1 0.01 0 0.14
185 INT207358 PTGDS Negative_regulation of CPOX 1 0.05 0 0.14
186 INT173498 EEF1A2 Regulation of Cpox 1 0.04 0.39 0.14
187 INT105439 IL6 Positive_regulation of CPOX 1 0.11 0.75 0.12
188 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
189 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
190 INT105434 TNF Positive_regulation of CPOX 1 0.27 0.75 0.12
191 INT207254 ZNF236 Positive_regulation of TXNIP 1 0.03 0.68 0.12
192 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12
193 INT178593 Binding of CPOX and TPX2 1 0.02 0.88 0.12
194 INT129092 Binding of GRP and Lyn 1 0.00 0.48 0.12
195 INT105436 IRF6 Positive_regulation of CPOX 1 0.08 0.74 0.11
196 INT211921 Gene_expression of Nek1 Positive_regulation of Cat 1 0.01 0.26 0.1
197 INT302511 Binding of OPA1 and Nos3 1 0.02 1.57 0.1
198 INT186246 Binding of CAT and SCN5A 1 0.03 0.47 0.1
199 INT91454 MAPK1 Positive_regulation of Gene_expression of CPOX 1 0.20 0.6 0.1
200 INT258517 Negative_regulation of CPOX Negative_regulation of Binding of PTGIR 1 0.04 0.33 0.1

Single Events

The table below shows the top 100 pain related interactions that have been reported for mitochondrial intermembrane space. They are ordered first by their pain relevance and then by number of times they were reported in mitochondrial intermembrane space. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29
2 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19
3 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02
4 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46
5 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81
6 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17
7 INT55944 Positive_regulation of Cpox 214 0.57 105.14 81.4
8 INT50672 Positive_regulation of CPOX 205 0.44 125.93 60.06
9 INT35975 Regulation of Cpox 109 0.39 57.88 49.69
10 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03
11 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77
12 INT64171 Regulation of CPOX 109 0.36 55.36 32.96
13 INT53949 Positive_regulation of Gene_expression of Cpox 82 0.65 38.12 25.93
14 INT64175 Negative_regulation of Gene_expression of CPOX 66 0.38 39.64 23.07
15 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84
16 INT69993 Positive_regulation of Gene_expression of Cpox 93 0.55 69.4 22.05
17 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61
18 INT81194 Binding of CPOX 40 0.29 23.7 18.95
19 INT55335 Binding of Cpox 49 0.34 15.48 18.46
20 INT78990 Regulation of Cpox 72 0.57 35.22 18.16
21 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04
22 INT73599 Negative_regulation of Gene_expression of Cpox 47 0.55 19.89 17.26
23 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76
24 INT75918 Negative_regulation of Negative_regulation of Cpox 19 0.23 10.05 14.4
25 INT53948 Regulation of Gene_expression of Cpox 40 0.51 20.97 13.87
26 INT50671 Regulation of Gene_expression of CPOX 45 0.54 30.99 13.83
27 INT83611 Negative_regulation of Gene_expression of Cpox 55 0.29 31.09 11.5
28 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67
29 INT74272 Localization of CPOX 39 0.63 25.12 10.53
30 INT79720 Positive_regulation of Cat 57 0.70 31.81 10.11
31 INT72759 Transcription of Cpox 40 0.39 17.26 10
32 INT76426 Positive_regulation of Negative_regulation of Cpox 18 0.35 6.84 9.95
33 INT74812 Negative_regulation of Positive_regulation of Cpox 17 0.34 10.1 9.94
34 INT75768 Transcription of Cpox 37 0.27 19.41 9.79
35 INT120509 Gene_expression of Cat 65 0.77 50.9 9.75
36 INT51922 Localization of Cpox 24 0.68 12.05 8.59
37 INT50290 Binding of Cpox 29 0.27 17.19 8.01
38 INT76427 Regulation of Negative_regulation of Cpox 17 0.31 6.75 7.93
39 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18
40 INT83529 Positive_regulation of Positive_regulation of Cpox 8 0.29 7.22 6.7
41 INT89603 Regulation of Negative_regulation of Cpox 11 0.30 10.59 6.28
42 INT77427 Regulation of Negative_regulation of CPOX 17 0.26 10.03 6.15
43 INT49440 Localization of Cpox 27 0.53 11.26 5.79
44 INT64176 Transcription of CPOX 35 0.41 15.1 5.5
45 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45
46 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38
47 INT38366 Regulation of Cat 45 0.62 23.45 5.34
48 INT85653 Regulation of Gene_expression of Cpox 24 0.24 20.55 5.22
49 INT120511 Positive_regulation of Gene_expression of Cat 26 0.69 19.82 5.2
50 INT33854 Localization of OPA1 19 0.65 10.55 5.04
51 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5
52 INT72758 Positive_regulation of Transcription of Cpox 15 0.34 5.46 4.75
53 INT69966 Positive_regulation of Negative_regulation of CPOX 11 0.45 6.18 4.64
54 INT77429 Negative_regulation of Negative_regulation of CPOX 9 0.34 5.09 4.64
55 INT96748 Gene_expression of GOLPH3 7 0.58 5.13 4.42
56 INT99905 Negative_regulation of Negative_regulation of Cpox 11 0.35 7.01 4.37
57 INT69967 Negative_regulation of Positive_regulation of CPOX 11 0.35 7.73 4.07
58 INT88651 Phosphorylation of Cpox 5 0.41 2.92 4.04
59 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
60 INT164540 Localization of Aifm1 15 0.46 13.87 3.65
61 INT14319 Localization of SHMT2 3 0.03 1.91 3.61
62 INT95119 Localization of CYCS 23 0.78 14.86 3.49
63 INT137634 Localization of Aifm1 17 0.80 11.8 3.45
64 INT24883 Regulation of OPA1 14 0.45 9.73 3.44
65 INT74022 Regulation of Positive_regulation of Cpox 6 0.24 5.73 3.41
66 INT12948 Positive_regulation of Gene_expression of Cat 17 0.67 6.46 3.12
67 INT3869 Gene_expression of SHMT2 7 0.37 3.6 3.03
68 INT5913 Binding of OPA1 12 0.41 9.33 2.92
69 INT79722 Regulation of Cat 14 0.62 5.88 2.86
70 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84
71 INT113892 Binding of Cat 6 0.48 3.95 2.65
72 INT195005 Positive_regulation of Aifm1 11 0.29 7.92 2.46
73 INT22129 Positive_regulation of Gene_expression of CAT 11 0.67 4.23 2.37
74 INT151574 Gene_expression of Aifm1 5 0.62 3.63 2.34
75 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
76 INT57360 Gene_expression of STAR 31 0.66 12.72 2.24
77 INT91276 Positive_regulation of Negative_regulation of Cpox 4 0.27 3.11 2.2
78 INT130199 Negative_regulation of Binding of CPOX 4 0.30 1.89 2.1
79 INT155234 Gene_expression of TXNIP 48 0.77 24.4 2.05
80 INT121036 Positive_regulation of Transcription of Cpox 12 0.21 6.34 2.04
81 INT66929 Positive_regulation of Localization of Cpox 6 0.25 4.68 1.98
82 INT123873 Positive_regulation of Negative_regulation of Cat 7 0.50 2.86 1.86
83 INT101166 Negative_regulation of Binding of Cpox 4 0.15 2.66 1.79
84 INT156005 Positive_regulation of Gene_expression of Aifm1 1 0.36 1.56 1.75
85 INT78005 Negative_regulation of Binding of Cpox 7 0.31 3.19 1.7
86 INT148804 Binding of Diablo 3 0.47 4.37 1.67
87 INT163666 Localization of Cat 8 0.80 5.84 1.57
88 INT44493 Regulation of SHMT2 3 0.29 0.45 1.55
89 INT72760 Regulation of Transcription of Cpox 6 0.24 1.84 1.54
90 INT68766 Positive_regulation of Transcription of CPOX 10 0.30 4.76 1.49
91 INT105086 Positive_regulation of CYCS 9 0.49 5.82 1.45
92 INT163523 Regulation of GOLPH3 2 0.08 1.57 1.41
93 INT141037 Positive_regulation of Aifm1 3 0.45 3.32 1.38
94 INT164541 Negative_regulation of Localization of Aifm1 3 0.27 4.51 1.38
95 INT19619 Positive_regulation of SHMT2 6 0.08 1.05 1.35
96 INT195013 Positive_regulation of Localization of Aifm1 1 0.27 4.18 1.29
97 INT37646 Negative_regulation of Aifm1 2 0.47 1.28 1.26
98 INT111340 Positive_regulation of Localization of CYCS 7 0.67 4.83 1.19
99 INT91122 Localization of CAT 6 0.78 4.13 1.19
100 INT82248 Positive_regulation of Regulation of Cpox 4 0.44 2.57 1.19
101 INT148228 Positive_regulation of Regulation of Cat 1 0.49 1.16 1.19
102 INT114243 Positive_regulation of Positive_regulation of Cpox 4 0.39 3.06 1.18
103 INT84714 Negative_regulation of Transcription of Cpox 3 0.25 1.5 1.18
104 INT104872 Positive_regulation of GOLPH3 3 0.18 1.34 1.15
105 INT12952 Negative_regulation of Gene_expression of Cat 16 0.57 7.44 1.14
106 INT22480 Binding of SHMT2 5 0.19 2.31 1.14
107 INT53028 Negative_regulation of CYCS 6 0.57 2.65 1.11
108 INT170317 Protein_catabolism of Cpox 4 0.15 0.43 1.1
109 INT141036 Negative_regulation of Aifm1 1 0.00 1.26 1.07
110 INT78354 Positive_regulation of Positive_regulation of CPOX 8 0.19 2.82 1.06
111 INT125356 Negative_regulation of Negative_regulation of Cat 4 0.42 2.66 1.06
112 INT81418 Positive_regulation of Localization of SHMT2 1 0.02 0.75 1.06
113 INT154842 Positive_regulation of Phosphorylation of Cpox 1 0.13 0.07 1.05
114 INT274898 Positive_regulation of Positive_regulation of Lyn 1 0.35 1.51 1.05
115 INT27587 Positive_regulation of STAR 7 0.46 6.37 0.99
116 INT201393 Positive_regulation of Regulation of CPOX 1 0.09 1.51 0.98
117 INT12945 Negative_regulation of Positive_regulation of Cat 3 0.41 2.61 0.97
118 INT53682 Regulation of Gene_expression of CAT 2 0.60 0.36 0.96
119 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95
120 INT55052 Binding of Cat 10 0.36 5.46 0.92
121 INT66314 Negative_regulation of Positive_regulation of CAT 4 0.42 0.8 0.91
122 INT149383 Binding of Lyn 1 0.36 1.14 0.91
123 INT142919 Regulation of Gene_expression of Cat 2 0.32 0.33 0.89
124 INT116141 Localization of Diablo 2 0.78 2.04 0.89
125 INT93747 Localization of Cat 9 0.56 4.25 0.88
126 INT154905 Negative_regulation of Phosphorylation of Cpox 1 0.18 0.91 0.87
127 INT130188 Positive_regulation of Negative_regulation of Cat 5 0.45 2.26 0.86
128 INT306786 Binding of STAR 3 0.47 1.71 0.86
129 INT99287 Binding of GOLPH3 6 0.35 2.87 0.85
130 INT1523 Binding of CYCS 4 0.47 0.53 0.8
131 INT195007 Positive_regulation of Gene_expression of Aifm1 1 0.40 4.75 0.79
132 INT195016 Gene_expression of Aifm1 8 0.45 5.92 0.78
133 INT64172 Regulation of Transcription of CPOX 1 0.19 0.31 0.75
134 INT113834 Regulation of Gatm 1 0.03 0.71 0.75
135 INT328226 Negative_regulation of Positive_regulation of Cpox 3 0.11 1.49 0.73
136 INT207285 Positive_regulation of Gene_expression of TXNIP 1 0.69 9.53 0.73
137 INT89801 Positive_regulation of Positive_regulation of Cat 2 0.49 0.21 0.71
138 INT133484 Negative_regulation of Localization of CYCS 4 0.42 2.77 0.7
139 INT169216 Negative_regulation of Positive_regulation of CYCS 1 0.42 0.82 0.7
140 INT90607 Positive_regulation of Binding of CPOX 4 0.17 0.79 0.67
141 INT272291 Regulation of Binding of CPOX 1 0.11 0.37 0.67
142 INT53022 Gene_expression of CYCS 5 0.65 4.01 0.66
143 INT195017 Negative_regulation of Positive_regulation of Aifm1 3 0.24 1.48 0.63
144 INT107417 Regulation of CAT 8 0.60 2.4 0.61
145 INT105444 Regulation of Localization of CPOX 1 0.22 1.28 0.59
146 INT312653 Negative_regulation of GOLPH3 1 0.06 1.08 0.59
147 INT47528 Regulation of GFER 2 0.29 1.47 0.58
148 INT76372 Regulation of Transcription of Cpox 3 0.16 0.57 0.57
149 INT64174 Negative_regulation of Transcription of CPOX 3 0.18 0.84 0.56
150 INT312652 Protein_catabolism of GOLPH3 1 0.09 0.9 0.56
151 INT117091 Positive_regulation of Lyn 1 0.49 0.41 0.56
152 INT266893 Negative_regulation of Gene_expression of Cat 4 0.58 3.76 0.55
153 INT130387 Binding of CAT 4 0.36 2.39 0.55
154 INT205917 Regulation of Localization of Cpox 2 0.19 0.22 0.54
155 INT99909 Regulation of Positive_regulation of CPOX 2 0.35 1.88 0.53
156 INT299420 Negative_regulation of Gene_expression of Star 1 0.33 6.66 0.5
157 INT261167 Gene_expression of GATM 1 0.75 0.16 0.47
158 INT261557 Positive_regulation of Localization of Cpox 2 0.04 0.17 0.45
159 INT26187 Regulation of CYCS 2 0.60 0.87 0.44
160 INT78991 Regulation of Positive_regulation of Cpox 2 0.22 3.86 0.44
161 INT158456 Positive_regulation of Localization of OPA1 1 0.43 0.34 0.43
162 INT136205 Positive_regulation of Regulation of Cat 1 0.38 0.51 0.43
163 INT126143 Positive_regulation of NLN 2 0.41 0.27 0.41
164 INT34976 Positive_regulation of Gene_expression of OPA1 4 0.43 4.21 0.4
165 INT137640 Negative_regulation of Localization of Aifm1 2 0.58 0.39 0.39
166 INT146295 Localization of GFER 1 0.68 1.46 0.38
167 INT84981 Negative_regulation of Gene_expression of CAT 3 0.41 0.35 0.35
168 INT92908 Negative_regulation of Regulation of Cpox 1 0.01 0.21 0.34
169 INT163803 Regulation of Gene_expression of Cat 3 0.61 1.51 0.33
170 INT160498 Regulation of Binding of Cpox 2 0.10 1.78 0.33
171 INT134079 Phosphorylation of OPA1 1 0.16 0.22 0.33
172 INT141647 Gene_expression of NLN 3 0.65 0.17 0.32
173 INT161434 Regulation of Negative_regulation of OPA1 1 0.03 0.2 0.32
174 INT314342 Positive_regulation of Localization of Cat 2 0.04 1.05 0.31
175 INT95065 Negative_regulation of Gatm 1 0.02 0.07 0.31
176 INT112531 Negative_regulation of Localization of Cpox 1 0.07 0.46 0.3
177 INT144868 Transcription of Cat 3 0.62 1.23 0.29
178 INT151685 Gene_expression of GFER 1 0.27 0.47 0.29
179 INT211917 Positive_regulation of Positive_regulation of Cat 1 0.62 0.97 0.29
180 INT141725 Regulation of Binding of Cpox 1 0.15 0.33 0.28
181 INT158564 Negative_regulation of Positive_regulation of Cat 2 0.37 1.27 0.27
182 INT232628 Gene_expression of Opa1 10 0.78 17.01 0.26
183 INT117830 Positive_regulation of Localization of CPOX 1 0.28 0.41 0.26
184 INT102828 Protein_catabolism of SHMT2 1 0.02 0 0.26
185 INT57359 Positive_regulation of Gene_expression of STAR 8 0.49 2.71 0.24
186 INT58442 Transcription of Cat 3 0.67 0.28 0.22
187 INT195004 Negative_regulation of Gene_expression of Aifm1 1 0.24 1.22 0.21
188 INT89580 Negative_regulation of STAR 16 0.35 14.88 0.2
189 INT261820 Phosphorylation of Lyn 5 0.30 1.41 0.2
190 INT191929 Negative_regulation of Transcription of Cpox 1 0.13 0.18 0.2
191 INT304142 Negative_regulation of Phosphorylation of Lyn 1 0.12 1.11 0.2
192 INT236499 Negative_regulation of Gene_expression of GOLPH3 1 0.05 0.09 0.2
193 INT39959 Negative_regulation of GFER 3 0.42 1.4 0.19
194 INT183623 Phosphorylation of Cpox 3 0.25 3.76 0.18
195 INT244270 Localization of GOLPH3 2 0.68 0.29 0.17
196 INT236049 Negative_regulation of SHMT2 1 0.04 0.13 0.17
197 INT244269 Regulation of Localization of GOLPH3 1 0.16 0.3 0.17
198 INT55051 Negative_regulation of Binding of Cat 2 0.35 0.61 0.16
199 INT278361 Positive_regulation of Gene_expression of Lyn 6 0.41 0.63 0.15
200 INT137649 Negative_regulation of NLN 1 0.22 0.08 0.15
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