GO:0005769

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Name early endosome
Categary Component
Go Slim No
Go Link GO:0005769
Unique Molecular Interactions 1034
Total Molecular Interactions 1469
Total Single Events 12049
Pain Genes Associated 104

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for early endosome. They are ordered first by their pain relevance and then by number of times they were reported for early endosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT269444 Binding of RAB5A and HHIP 1 0.04 0 5.79
2 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64
3 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
4 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
5 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
6 INT32586 H2-Ab1 Regulation of Pomc 1 0.03 0.14 2.19
7 INT32585 H2-Ab1 Negative_regulation of Pomc 1 0.03 0.13 2
8 INT305741 Binding of Kcnk2 and Sort1 1 0.54 1.01 1.8
9 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79
10 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
11 INT18786 Binding of Adra2a and Nisch 2 0.19 0 1.7
12 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
13 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53
14 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
15 INT29093 Binding of H2-Ab1 and Rbm39 1 0.06 0 1.5
16 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
17 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
18 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
19 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34
20 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
21 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
22 INT162419 Binding of Abpa and Cftr 1 0.04 1.66 1.19
23 INT139736 Htr1a Positive_regulation of Mapk3 1 0.54 0.13 1.19
24 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
25 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
26 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
27 INT164378 MAPK3 Positive_regulation of Transcription of PDYN 1 0.50 0.2 1.09
28 INT305734 Binding of Sort1 and Trpv1 1 0.01 0.5 1.08
29 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
30 INT54486 Npepo Positive_regulation of Gene_expression of Rabep2 1 0.14 0 1.08
31 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
32 INT269443 Positive_regulation of Binding of RAB5A and HHIP 1 0.04 0 1.06
33 INT145408 H2-Ab1 Negative_regulation of Gene_expression of Dbi 1 0.05 0 1.06
34 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
35 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
36 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
37 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99
38 INT311102 IL8 Positive_regulation of CXCR7 1 0.00 1.74 0.98
39 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
40 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
41 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
42 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
43 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
44 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
45 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
46 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
47 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
48 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
49 INT281089 Binding of Gria1 and Ltp 1 0.25 0.6 0.9
50 INT305742 Binding of Sort1 and Gtf3a 1 0.01 0.64 0.88
51 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
52 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
53 INT97738 Mdk Positive_regulation of Mapk3 1 0.08 0.66 0.87
54 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
55 INT97735 Trib3 Positive_regulation of Mapk3 1 0.05 0.66 0.87
56 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85
57 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85
58 INT174509 Binding of CD4 and CD28 1 0.26 1.68 0.84
59 INT127545 Gria1 Positive_regulation of Gene_expression of Gnptab 1 0.00 0.7 0.83
60 INT269455 Binding of RAB5A and GOPC 1 0.08 0 0.82
61 INT16438 Atp6v0d2 Regulation of Localization of Lnpep 1 0.01 0 0.81
62 INT16439 Atp6v0d2 Regulation of Localization of Avp 1 0.02 0 0.81
63 INT63544 Adra2a Regulation of Nisch 1 0.18 0 0.79
64 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78
65 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
66 INT232621 Binding of Gria1 and Psd 1 0.10 0.29 0.77
67 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
68 INT329120 Binding of KCNA1 and CNTNAP2 1 0.09 1.23 0.75
69 INT86657 TNF Regulation of H2-Ab1 1 0.02 0.84 0.74
70 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
71 INT311525 Binding of Gria1 and Ltp 1 0.00 0.1 0.73
72 INT329119 Binding of CNTN2 and CNTNAP2 1 0.08 2.41 0.73
73 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
74 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72
75 INT216654 Binding of P2ry2 and DRGX 1 0.01 1.59 0.71
76 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
77 INT190984 Binding of Scn2a1 and Gria1 1 0.03 0.08 0.71
78 INT772 Tf Positive_regulation of Positive_regulation of Oprl1 1 0.11 0 0.7
79 INT778 Tf Positive_regulation of Gh1 1 0.14 0 0.7
80 INT51433 Gria1 Positive_regulation of Eif3g 1 0.03 0 0.7
81 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
82 INT782 Tf Positive_regulation of Prl 1 0.43 0 0.7
83 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
84 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7
85 INT170832 Cftr Regulation of Scnn1a 2 0.16 1.2 0.67
86 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
87 INT211915 Fig4 Positive_regulation of Mapk3 1 0.12 0.25 0.66
88 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66
89 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66
90 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
91 INT281083 Binding of Gria1 and Gipc1 1 0.01 0 0.65
92 INT112218 Ntsr2 Positive_regulation of H2-Ab1 1 0.06 0 0.64
93 INT216644 Binding of P2ry1 and P2ry2 1 0.24 0.55 0.64
94 INT253137 Ptpn1 Negative_regulation of Ins1 1 0.19 4.11 0.63
95 INT169296 PTPLA Positive_regulation of MAPK3 1 0.10 0.15 0.63
96 INT174500 Positive_regulation of Binding of CD4 and HLA-B 1 0.21 2.33 0.63
97 INT128275 Slc17a7 Positive_regulation of Transcription of Slc17a6 1 0.39 0.27 0.63
98 INT54487 Rabep2 Regulation of Gene_expression of Jun 1 0.06 0 0.61
99 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
100 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
101 INT40901 Trf Regulation of Localization of POMC 1 0.07 0.56 0.6
102 INT223158 Mapk3 Regulation of Gene_expression of Mapk14 1 0.48 1.33 0.59
103 INT120206 Binding of UTS2R and Il1 1 0.17 1.28 0.59
104 INT296463 Binding of Gria1 and Pick1 1 0.16 0.32 0.59
105 INT120207 Binding of UTS2R and Il1f5 1 0.09 1.28 0.59
106 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
107 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
108 INT296456 Gria1 Negative_regulation of Rbm39 1 0.00 0.45 0.57
109 INT39210 TF Positive_regulation of Gene_expression of IL2 1 0.17 0.07 0.57
110 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57
111 INT27871 Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
112 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
113 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56
114 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56
115 INT170833 Cftr Negative_regulation of Slc10a2 1 0.47 0.31 0.56
116 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55
117 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
118 INT281087 Binding of Gria1 and Hmmr 1 0.04 0 0.55
119 INT99486 OPRM1 Positive_regulation of MAPK3 1 0.22 0 0.55
120 INT16643 Nppa Regulation of Rabep2 1 0.13 0.07 0.55
121 INT312751 Phosphorylation of Gria1 Positive_regulation of GRIA1 1 0.18 0.22 0.55
122 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
123 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54
124 INT311521 Gnrhr Positive_regulation of Gene_expression of Gria1 1 0.00 0.54 0.54
125 INT311522 Gnrhr Positive_regulation of Transcription of Gria1 1 0.00 0.54 0.54
126 INT323146 PRKCA Positive_regulation of MAPK1 1 0.02 0 0.54
127 INT192160 Cxcl9 Negative_regulation of Furin 1 0.02 0.8 0.54
128 INT85125 IL3 Positive_regulation of MAPK1 1 0.30 0.81 0.53
129 INT269449 Positive_regulation of Binding of RAB5A and GOPC 1 0.11 0 0.53
130 INT54485 Positive_regulation of Akr1d1 Positive_regulation of Gene_expression of Rabep2 1 0.00 0 0.53
131 INT85121 CSF2 Positive_regulation of MAPK1 1 0.07 0.8 0.53
132 INT85115 IL5 Positive_regulation of MAPK1 1 0.14 0.81 0.53
133 INT192162 Furin Positive_regulation of Mmp14 1 0.10 0.79 0.53
134 INT106394 MAPK3 Positive_regulation of ADRBK1 1 0.48 0.06 0.53
135 INT79593 Binding of Reg1 and LMTK2 1 0.00 0.32 0.53
136 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
137 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52
138 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
139 INT232618 Gene_expression of Grid2ip Regulation of Localization of Gria1 1 0.28 0.86 0.52
140 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52
141 INT144130 Binding of Gja1 and Prkcg 1 0.48 0.5 0.52
142 INT201939 CXCL10 Positive_regulation of MAPK1 1 0.11 0.72 0.52
143 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
144 INT349130 Phosphorylation of Gria1 Positive_regulation of Shisa9 1 0.00 0.49 0.52
145 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52
146 INT122872 SEMA6A Positive_regulation of MAPK1 1 0.56 0 0.52
147 INT69291 Cftr Positive_regulation of Localization of Slc4a8 1 0.04 0.38 0.51
148 INT117482 CFTR Negative_regulation of THRB 1 0.01 0.15 0.51
149 INT131368 MAPK1 Positive_regulation of Bcar3 1 0.00 0.37 0.51
150 INT62299 Binding of CD4 and SGCG 1 0.39 1.23 0.51
151 INT131371 MAPK3 Positive_regulation of Il4 1 0.02 0.37 0.51
152 INT131367 MAPK3 Positive_regulation of Bcar3 1 0.00 0.37 0.51
153 INT334901 LDLR Positive_regulation of Crp 1 0.00 1.48 0.51
154 INT131370 MAPK3 Positive_regulation of Gene_expression of Il4 1 0.02 0.37 0.51
155 INT131369 MAPK1 Positive_regulation of Il4 1 0.01 0.37 0.51
156 INT356286 Ngf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
157 INT356279 Gdnf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
158 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
159 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
160 INT153897 Binding of KCNJ3 and Snx27 1 0.03 0.28 0.5
161 INT324816 Hspd1 Positive_regulation of Gene_expression of Ik 1 0.00 1.59 0.5
162 INT194676 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.34 0.5
163 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
164 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
165 INT296457 Camk2a Positive_regulation of Phosphorylation of Gria1 1 0.19 0.28 0.49
166 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
167 INT259183 Gria1 Positive_regulation of Phosphorylation of Gria2 1 0.30 0.39 0.49
168 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
169 INT232619 Binding of Gria1 and Grid2ip 1 0.23 0.51 0.48
170 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48
171 INT273110 Bdnf Regulation of Positive_regulation of Gria1 1 0.43 0 0.47
172 INT102552 HGF Positive_regulation of MAPK3 1 0.38 0.47 0.47
173 INT251297 Binding of C2 and CD4 1 0.04 0.35 0.47
174 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
175 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47
176 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
177 INT119598 H2-Ab1 Regulation of Scn4a 1 0.00 0.09 0.46
178 INT132445 TF Positive_regulation of IL8 1 0.11 2.23 0.46
179 INT92743 Binding of NF2 and LMOD1 1 0.00 0.08 0.46
180 INT69638 Binding of TF and Zfp354a 1 0.00 0 0.46
181 INT341623 Binding of CFTR and CTRC 1 0.35 1.22 0.46
182 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
183 INT341624 Binding of CFTR and PRSS1 1 0.39 1.01 0.45
184 INT191489 Positive_regulation of P2ry2 Negative_regulation of Positive_regulation of Trpv1 1 0.03 0.08 0.44
185 INT84517 IRF6 Positive_regulation of TF 1 0.14 0.19 0.44
186 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
187 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44
188 INT215564 Hmmr Negative_regulation of P2ry2 1 0.00 0 0.44
189 INT329116 Binding of LGI1 and CNTNAP2 1 0.38 1.3 0.44
190 INT264473 Il1a Positive_regulation of Mapk1 1 0.00 0 0.43
191 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43
192 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
193 INT264471 Il1a Positive_regulation of Gene_expression of Mapk1 1 0.01 0 0.43
194 INT86069 Positive_regulation of Gria1 Positive_regulation of Gene_expression of Fos 1 0.11 0.3 0.42
195 INT127543 Gria1 Positive_regulation of Gene_expression of Cryge 1 0.00 0.35 0.42
196 INT74713 Binding of Gria1 and Olr1868 1 0.00 0 0.42
197 INT106396 DYT10 Positive_regulation of MAPK3 1 0.50 0 0.42
198 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 0.11 0.39 0.42
199 INT127546 Gria1 Positive_regulation of Gene_expression of Kcnab3 1 0.02 0.35 0.42
200 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42

Single Events

The table below shows the top 100 pain related interactions that have been reported for early endosome. They are ordered first by their pain relevance and then by number of times they were reported in early endosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
2 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
3 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
4 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
5 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
6 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74
7 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92
8 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
9 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05
10 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
11 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
12 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
13 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27
14 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
15 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
16 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
17 INT37889 Gene_expression of P2ry2 75 0.65 26.01 23.8
18 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
19 INT76249 Gene_expression of Gria1 67 0.75 15.07 22.78
20 INT103842 Gene_expression of Cftr 53 0.78 59.59 21.82
21 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
22 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31
23 INT129987 Phosphorylation of Gria1 63 0.80 20.65 21.02
24 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
25 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88
26 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
27 INT12922 Gene_expression of Atp9a 115 0.75 50.95 17.01
28 INT107928 Gene_expression of Slc17a6 34 0.76 3.76 16.64
29 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
30 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38
31 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
32 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89
33 INT61635 Positive_regulation of P2ry2 35 0.56 12.08 14.68
34 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
35 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
36 INT49538 Binding of Gria1 22 0.47 2.66 13.35
37 INT48927 Regulation of Mapk3 25 0.60 14.06 12.82
38 INT84307 Binding of Cftr 31 0.47 26.19 12.8
39 INT11766 Negative_regulation of H2-Ab1 15 0.43 5.27 12.32
40 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23
41 INT111948 Positive_regulation of Gria1 23 0.61 7.55 12.03
42 INT36287 Binding of CD4 96 0.47 58.93 11.88
43 INT3699 Gene_expression of H2-Ab1 24 0.74 12.06 11.82
44 INT2956 Binding of H2-Ab1 19 0.37 3.1 11.18
45 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
46 INT13240 Gene_expression of TF 94 0.76 57.81 10.99
47 INT139935 Gene_expression of Slc17a6 36 0.78 8.43 10.61
48 INT48921 Regulation of Mapk1 25 0.49 19.51 10.41
49 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38
50 INT16404 Regulation of CD4 54 0.61 33.05 10.29
51 INT8072 Localization of Gria1 17 0.75 2.62 10.04
52 INT119892 Gene_expression of Cftr 54 0.77 23.76 9.73
53 INT96298 Negative_regulation of Gria1 25 0.57 10.61 9.7
54 INT105816 Gene_expression of P2RY2 53 0.78 16.47 9.67
55 INT77282 Positive_regulation of Cftr 23 0.69 21.8 9.65
56 INT101891 Negative_regulation of Cftr 25 0.58 24.09 9.55
57 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
58 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
59 INT109432 Negative_regulation of Phosphorylation of Mapk1 19 0.54 7.01 8.98
60 INT111133 Negative_regulation of Mapk3 31 0.57 10.89 8.9
61 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34
62 INT71785 Gene_expression of MAPK3 22 0.75 11.35 8.21
63 INT135443 Phosphorylation of Map2k1 11 0.80 2.44 8.01
64 INT82762 Positive_regulation of Positive_regulation of Mapk3 23 0.67 7.72 7.91
65 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87
66 INT135441 Positive_regulation of Map2k1 15 0.67 6.6 7.87
67 INT72372 Positive_regulation of Phosphorylation of Mapk3 30 0.67 13.6 7.69
68 INT91618 Positive_regulation of Phosphorylation of MAPK3 21 0.67 7.99 7.65
69 INT111680 Gene_expression of P2ry2 20 0.58 9.23 7.39
70 INT76253 Positive_regulation of P2RY2 29 0.70 13.99 7.33
71 INT327801 Positive_regulation of Gene_expression of Aqp2 6 0.44 7.67 7.24
72 INT57023 Negative_regulation of Gene_expression of Gria1 20 0.58 6.92 7.17
73 INT197493 Localization of Apoe 61 0.79 27.48 7.06
74 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05
75 INT138802 Gene_expression of CFTR 36 0.70 18.8 7.02
76 INT69289 Negative_regulation of Cftr 44 0.57 13.28 6.97
77 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
78 INT64671 Gene_expression of NISCH 10 0.69 2.19 6.9
79 INT17049 Localization of CD4 57 0.75 35.33 6.89
80 INT139149 Binding of Gria1 22 0.37 5.71 6.88
81 INT95466 Regulation of P2ry2 23 0.56 3.66 6.86
82 INT10568 Regulation of H2-Ab1 9 0.20 1.86 6.79
83 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
84 INT120298 Negative_regulation of Phosphorylation of Gria1 6 0.57 8.99 6.68
85 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59
86 INT87775 Phosphorylation of Gja1 13 0.82 2.75 6.56
87 INT93137 Negative_regulation of Map2k1 17 0.42 4.51 6.49
88 INT234813 Gene_expression of RAB5A 58 0.66 3.67 6.48
89 INT60161 Gene_expression of EPHA3 43 0.75 3.66 6.25
90 INT14054 Positive_regulation of H2-Ab1 10 0.69 2.98 6.25
91 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
92 INT94197 Negative_regulation of Phosphorylation of MAPK3 13 0.57 5.51 6.18
93 INT48926 Positive_regulation of Gene_expression of Mapk3 12 0.46 6.02 6.13
94 INT139964 Regulation of Phosphorylation of Mapk1 12 0.58 10.04 6.1
95 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96
96 INT94927 Transcription of Gria1 12 0.69 3.14 5.94
97 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9
98 INT63042 Binding of Apoe 59 0.48 31.23 5.88
99 INT86119 Regulation of Cftr 13 0.45 14.08 5.75
100 INT139933 Negative_regulation of Slc17a6 3 0.59 10.25 5.43
101 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39
102 INT99487 Negative_regulation of MAPK3 15 0.57 7.13 5.39
103 INT213741 Gene_expression of Kdr 60 0.75 44.24 5.35
104 INT135440 Positive_regulation of Phosphorylation of Map2k1 5 0.49 1.32 5.22
105 INT22597 Positive_regulation of TF 43 0.68 27.27 5.17
106 INT151102 Positive_regulation of CFTR 22 0.61 15.27 5.12
107 INT89114 Binding of Cftr 13 0.37 11.29 4.99
108 INT201653 Gene_expression of Sort1 6 0.75 6.29 4.89
109 INT255981 Localization of RAB5A 3 0.68 0.88 4.76
110 INT269476 Binding of RAB5A 1 0.41 0 4.76
111 INT170757 Positive_regulation of Gene_expression of Cftr 3 0.51 11.41 4.75
112 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
113 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56
114 INT169756 Binding of CFTR 9 0.35 9.65 4.55
115 INT112038 Positive_regulation of P2ry2 8 0.45 2.41 4.4
116 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38
117 INT11565 Gene_expression of Tf 24 0.68 5.89 4.36
118 INT50713 Positive_regulation of Nisch 6 0.69 1.5 4.33
119 INT148901 Binding of Sort1 2 0.39 3.65 4.32
120 INT18785 Binding of Nisch 12 0.43 1.03 4.28
121 INT87780 Gene_expression of Gja1 22 0.77 5.84 4.24
122 INT48993 Positive_regulation of Cftr 17 0.57 6.02 4.12
123 INT92902 Negative_regulation of Positive_regulation of Gria1 6 0.57 1.06 4.1
124 INT88156 Regulation of Gria1 12 0.54 2.5 4.06
125 INT133244 Regulation of Positive_regulation of Mapk1 11 0.43 3.52 4.03
126 INT89113 Regulation of Cftr 11 0.62 6.83 4.01
127 INT112782 Localization of Mapk3 8 0.78 1.87 3.98
128 INT106065 Negative_regulation of MAP2K1 27 0.57 12.69 3.97
129 INT179391 Phosphorylation of Map2k2 1 0.02 7.01 3.89
130 INT129990 Positive_regulation of Phosphorylation of Gria1 11 0.61 3.44 3.87
131 INT94291 Regulation of Gene_expression of Mapk3 4 0.40 3.05 3.8
132 INT151099 Negative_regulation of CFTR 12 0.59 10.28 3.79
133 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
134 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
135 INT73981 Gene_expression of Hspd1 18 0.75 5.69 3.72
136 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
137 INT123908 Positive_regulation of HLA-DQB1 12 0.21 10.5 3.71
138 INT107586 Transcription of Slc17a6 6 0.61 0.79 3.68
139 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6
140 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
141 INT12923 Negative_regulation of Atp9a 17 0.35 7.87 3.52
142 INT57728 Regulation of LDLR 25 0.41 13.18 3.46
143 INT148899 Regulation of Sort1 2 0.50 2.72 3.46
144 INT118270 Regulation of P2RY2 16 0.45 7.02 3.45
145 INT4545 Negative_regulation of Nox1 15 0.53 10.08 3.4
146 INT126560 Binding of P2RY2 12 0.44 6.43 3.4
147 INT129751 Regulation of Phosphorylation of Mapk3 11 0.55 3.91 3.35
148 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32
149 INT5166 Binding of Ldlr 14 0.48 11.95 3.32
150 INT102347 Localization of P2ry2 4 0.56 1.23 3.31
151 INT97737 Negative_regulation of Phosphorylation of Mapk3 9 0.57 5.64 3.3
152 INT84564 Regulation of Positive_regulation of Gria1 2 0.33 1.86 3.3
153 INT51427 Positive_regulation of Positive_regulation of Gria1 11 0.45 1.33 3.28
154 INT72141 Binding of Apoe 11 0.37 10.91 3.27
155 INT81280 Binding of Atp9a 20 0.47 11.14 3.24
156 INT97710 Localization of Apoe 1 0.79 7.18 3.2
157 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
158 INT170343 Positive_regulation of Gene_expression of Gria1 10 0.61 2.77 3.09
159 INT174117 Gene_expression of Cd1d1 26 0.75 12.07 3.07
160 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05
161 INT71783 Positive_regulation of Gene_expression of MAPK3 9 0.59 4.59 3.05
162 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04
163 INT87288 Positive_regulation of Positive_regulation of MAPK3 5 0.67 1.62 3.04
164 INT106919 Regulation of Slc17a6 8 0.42 0.88 3.02
165 INT329148 Gene_expression of CNTNAP2 17 0.76 6 2.95
166 INT51099 Negative_regulation of Nisch 6 0.43 0.97 2.93
167 INT46650 Localization of Trf 13 0.61 4.4 2.91
168 INT200895 Localization of Mapk1 6 0.67 2.08 2.82
169 INT271447 Positive_regulation of Positive_regulation of HLA-DQB1 1 0.06 5.87 2.8
170 INT169112 Negative_regulation of Positive_regulation of Mapk1 9 0.59 1.84 2.78
171 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73
172 INT152927 Negative_regulation of Mapk1 16 0.41 5.85 2.73
173 INT234825 Positive_regulation of Gene_expression of RAB5A 16 0.59 1.15 2.71
174 INT91284 Negative_regulation of P2ry2 8 0.25 2.66 2.71
175 INT17033 Positive_regulation of Trf 21 0.62 11.76 2.68
176 INT100360 Negative_regulation of TF 19 0.42 10.43 2.68
177 INT50080 Binding of APOE 38 0.45 29.61 2.67
178 INT131973 Positive_regulation of Transcription of Gria1 3 0.49 0.35 2.62
179 INT162682 Phosphorylation of Atp9a 1 0.80 0 2.57
180 INT179396 Positive_regulation of Map2k2 7 0.30 2.84 2.56
181 INT139148 Negative_regulation of Gene_expression of Gria1 6 0.51 0.89 2.56
182 INT269377 Positive_regulation of EPHA3 22 0.18 0.97 2.55
183 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54
184 INT69290 Localization of Cftr 11 0.75 3.69 2.52
185 INT107846 Transcription of P2ry2 6 0.46 2.06 2.52
186 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
187 INT170350 Localization of Gria1 7 0.65 2.36 2.51
188 INT153997 Negative_regulation of Gene_expression of Slc17a6 2 0.59 3.01 2.42
189 INT87284 Negative_regulation of Positive_regulation of MAPK3 7 0.41 2.65 2.38
190 INT126033 Localization of Slc17a6 4 0.77 0.75 2.35
191 INT150465 Positive_regulation of Gene_expression of P2ry2 3 0.56 3.48 2.33
192 INT170712 Gene_expression of Siah1a 1 0.77 2.33 2.33
193 INT186116 Regulation of Gene_expression of MAPK1 9 0.44 5.85 2.32
194 INT86315 Transcription of Cftr 7 0.53 4.24 2.3
195 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
196 INT137977 Localization of P2RY2 5 0.80 3.07 2.27
197 INT202522 Negative_regulation of Gene_expression of Cftr 11 0.57 5.9 2.24
198 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
199 INT27880 Positive_regulation of HSPD1 17 0.65 18.16 2.23
200 INT151816 Negative_regulation of P2ry2 3 0.02 3.1 2.23
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