GO:0005773

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Name vacuole
Categary Component
Go Slim Yes
Go Link GO:0005773
Unique Molecular Interactions 25
Total Molecular Interactions 41
Total Single Events 251
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for vacuole. They are ordered first by their pain relevance and then by number of times they were reported for vacuole. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
2 INT76378 Binding of Cit and Flvcr2 1 0.09 0.17 1.15
3 INT90385 EXTL3 Regulation of Ctsl 1 0.00 1.1 0.98
4 INT141605 Gene_expression of Ctsl Positive_regulation of Positive_regulation of MET 1 0.34 0 0.8
5 INT76379 Negative_regulation of Binding of Cit and Flvcr2 1 0.11 0.08 0.58
6 INT76377 Regulation of Binding of Cit and Flvcr2 1 0.07 0.09 0.57
7 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
8 INT346205 Binding of CD74 and TPPP 1 0.02 0.87 0.51
9 INT195774 Binding of MIF and Cd74 1 0.02 1.15 0.46
10 INT174459 IL8 Positive_regulation of Gene_expression of Cd74 1 0.00 0.61 0.35
11 INT28688 Binding of Kng1 and Ctsl1 1 0.15 0 0.31
12 INT178269 Slc11a2 Regulation of a 1 0.06 0.97 0.16
13 INT43495 Cd74 Regulation of Gene_expression of Ifng 1 0.47 0 0.14
14 INT204159 Slc11a2 Regulation of Gene_expression of HAMP 1 0.11 1.08 0.14
15 INT298052 Binding of Cd74 and Vip 1 0.00 1.05 0.13
16 INT288701 Epas1 Regulation of Transcription of Slc11a2 1 0.29 0.38 0.13
17 INT87839 Binding of Cd74 and Dcn 1 0.36 0.21 0.13
18 INT337084 Negative_regulation of Binding of Cd74 and Mif 1 0.29 1.64 0.08
19 INT348820 Cd74 Regulation of Gene_expression of TFDP3 1 0.07 0.16 0.04
20 INT272609 Binding of Cit and Dlg4 1 0.11 0 0.03
21 INT289294 Binding of CD59 and Atp6ap1 1 0.10 0.51 0
22 INT289298 Negative_regulation of Binding of CD59 and Atp6ap1 1 0.12 0.51 0
23 INT331090 Binding of Ctsl and Itga2 1 0.10 0.2 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for vacuole. They are ordered first by their pain relevance and then by number of times they were reported in vacuole. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT47301 Gene_expression of Ctsl 27 0.76 7.72 9.32
2 INT253970 Positive_regulation of Cd74 3 0.48 8.16 4.09
3 INT47298 Localization of Ctsl 13 0.79 3.77 4.08
4 INT187168 Binding of Cd74 13 0.27 11.2 3.44
5 INT167039 Gene_expression of Cd74 24 0.40 17.12 2.84
6 INT76375 Binding of Cit 6 0.12 0.39 2.77
7 INT243350 Binding of CD74 2 0.11 4.86 2.72
8 INT47303 Regulation of Ctsl 10 0.56 2.64 2.04
9 INT58208 Negative_regulation of Ctsl 8 0.53 3.49 1.91
10 INT253975 Binding of Cd74 4 0.27 4.57 1.88
11 INT47302 Regulation of Gene_expression of Ctsl 2 0.53 0.54 1.77
12 INT76376 Negative_regulation of Binding of Cit 1 0.15 0.22 1.64
13 INT271443 Regulation of Cd74 1 0.33 2.73 1.4
14 INT47305 Positive_regulation of Gene_expression of Ctsl 5 0.59 2.06 1.12
15 INT6534 Negative_regulation of Ctsl1 3 0.54 0.11 0.94
16 INT132883 Gene_expression of Slc11a2 5 0.75 2.96 0.89
17 INT116058 Gene_expression of Cd74 2 0.56 0.55 0.89
18 INT174420 Positive_regulation of Gene_expression of Cd74 3 0.20 1.92 0.81
19 INT120046 Negative_regulation of Localization of Ctsl 2 0.40 0.31 0.8
20 INT279647 Regulation of Cit 1 0.27 0 0.64
21 INT116060 Negative_regulation of Gene_expression of Cd74 1 0.12 0 0.61
22 INT28687 Gene_expression of Ctsl1 4 0.61 0.48 0.57
23 INT51843 Localization of Ctsl1 3 0.62 0.54 0.54
24 INT160148 Positive_regulation of Ctsl 2 0.43 0.74 0.52
25 INT271439 Positive_regulation of Localization of Cd74 1 0.36 1.01 0.52
26 INT272569 Gene_expression of Cit 2 0.40 0 0.5
27 INT271435 Localization of Cd74 1 0.54 0.95 0.49
28 INT174418 Regulation of Gene_expression of Cd74 1 0.04 0.9 0.46
29 INT6533 Binding of Ctsl1 2 0.34 0 0.45
30 INT279645 Binding of Cit 1 0.29 0.46 0.45
31 INT254172 Negative_regulation of Gene_expression of Cd74 1 0.24 1.03 0.44
32 INT348083 Positive_regulation of Ctsl1 1 0.08 0.21 0.4
33 INT224637 Protein_catabolism of Ctsl 1 0.12 0.76 0.37
34 INT62874 Gene_expression of CD74 1 0.00 0.64 0.37
35 INT6536 Negative_regulation of Binding of Ctsl1 1 0.39 0 0.3
36 INT36060 Protein_catabolism of Ctsl1 2 0.83 0.15 0.22
37 INT124178 Regulation of Ctsl1 1 0.23 0.19 0.22
38 INT220862 Negative_regulation of Transcription of Ctsl 1 0.05 0.41 0.21
39 INT220859 Transcription of Ctsl 1 0.09 0.41 0.21
40 INT204148 Regulation of Gene_expression of Slc11a2 1 0.15 1.1 0.15
41 INT47304 Regulation of Localization of Ctsl 1 0.23 0.14 0.15
42 INT348081 Positive_regulation of Gene_expression of Ctsl1 1 0.06 0.24 0.14
43 INT47300 Negative_regulation of Gene_expression of Ctsl 1 0.57 0.14 0.14
44 INT288681 Regulation of Transcription of Slc11a2 1 0.44 0.37 0.13
45 INT288683 Transcription of Slc11a2 1 0.69 0.37 0.13
46 INT288682 Binding of Slc11a2 1 0.47 0 0.12
47 INT131015 Negative_regulation of Cd74 1 0.17 0.25 0.12
48 INT47299 Positive_regulation of Localization of Ctsl 1 0.40 0.15 0.12
49 INT279642 Negative_regulation of Cit 1 0.25 0 0.1
50 INT36061 Negative_regulation of Protein_catabolism of Ctsl1 1 0.12 0.08 0.1
51 INT279640 Regulation of Gene_expression of Cit 1 0.27 0 0.07
52 INT180694 Regulation of Localization of Ctsl1 1 0.16 0 0.05
53 INT324127 Positive_regulation of Cd74 2 0.07 1.34 0.04
54 INT194148 Positive_regulation of CD74 2 0.27 0.68 0
55 INT324126 Negative_regulation of Binding of Cd74 1 0.08 0.31 0
56 INT104239 Negative_regulation of Cit 1 0.06 0 0
57 INT324125 Positive_regulation of Binding of Cd74 1 0.09 0.62 0
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