GO:0005788

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Name endoplasmic reticulum lumen
Categary Component
Go Slim No
Go Link GO:0005788
Unique Molecular Interactions 1327
Total Molecular Interactions 1837
Total Single Events 20229
Pain Genes Associated 83

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for endoplasmic reticulum lumen. They are ordered first by their pain relevance and then by number of times they were reported for endoplasmic reticulum lumen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
3 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
4 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
5 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
6 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
7 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
8 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
9 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
10 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
11 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
12 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
13 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
14 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
15 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
16 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
17 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
18 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
19 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62
20 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46
21 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
22 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
23 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
24 INT139723 PROC Positive_regulation of MAPK8 1 0.01 2.98 2.33
25 INT108987 Ngf Regulation of Gene_expression of Sit1 1 0.00 1.46 2.32
26 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
27 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
28 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
29 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
30 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
31 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
32 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
33 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
34 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
35 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85
36 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
37 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
38 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73
39 INT80199 Ngf Regulation of Transcription of Rab38 1 0.01 1.48 1.68
40 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
41 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
42 INT266768 NGF Positive_regulation of Localization of SFTPA1 1 0.01 1.65 1.6
43 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
44 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
45 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
46 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54
47 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53
48 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
49 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48
50 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
51 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
52 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
53 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43
54 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
55 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
56 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
57 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
58 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
59 INT60993 Ntf4 Negative_regulation of Positive_regulation of CRTAC1 1 0.00 0 1.37
60 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
61 INT60992 Ngf Regulation of CRTAC1 1 0.00 0 1.35
62 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35
63 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34
64 INT140531 Ngf Positive_regulation of DYT10 1 0.72 1.83 1.34
65 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
66 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
67 INT181492 NGF Regulation of TRPV1 1 0.21 0.93 1.31
68 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 0.01 0.81 1.31
69 INT139722 PROC Positive_regulation of CDCP1 1 0.00 1.61 1.29
70 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
71 INT149844 Negative_regulation of Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.26
72 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25
73 INT149845 Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.24
74 INT121729 Negative_regulation of Ngf Positive_regulation of Ephb1 1 0.24 0.69 1.22
75 INT121724 Ngf Positive_regulation of Ephb1 1 0.40 0.68 1.21
76 INT108065 Negative_regulation of Binding of Ngf and IgG-2a 1 0.01 2.38 1.2
77 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
78 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2
79 INT108064 Binding of Ngf and IgG-2a 1 0.01 2.36 1.19
80 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
81 INT170655 Binding of Csf2 and Ngf 1 0.36 1.25 1.18
82 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17
83 INT93290 Ngf Regulation of Transcription of Trpv1 1 0.02 0.34 1.16
84 INT335435 Ngf Positive_regulation of Ltb4r 1 0.52 1.06 1.16
85 INT93289 Ngf Regulation of Trpv1 1 0.05 0.34 1.16
86 INT122369 Tacr1 Positive_regulation of Ngf 1 0.30 0.16 1.14
87 INT160540 Binding of NGF and PSIP1 2 0.29 1.43 1.12
88 INT121728 Ngf Positive_regulation of Phosphorylation of Pik3cb 1 0.45 0.69 1.11
89 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
90 INT105690 Ngf Positive_regulation of TRPV1 1 0.05 1.43 1.08
91 INT181494 TRPV3 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07
92 INT181493 TRPV4 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07
93 INT120315 Gnrhr Negative_regulation of Positive_regulation of Ngf 1 0.11 0.85 1.07
94 INT120318 Gnrhr Negative_regulation of Ngf 1 0.11 0.85 1.07
95 INT69340 Binding of Igh-6 and Ngf 2 0.06 1.04 1.06
96 INT87320 Ngf Regulation of Gene_expression of Bdnf 2 0.38 0.97 1.06
97 INT120317 Ghrh Regulation of Positive_regulation of Ngf 1 0.25 0.95 1.06
98 INT120311 Ghrh Regulation of Gene_expression of Ngf 1 0.25 0.95 1.06
99 INT93614 Ngf Positive_regulation of Ntrk1 2 0.52 0.85 1.05
100 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05
101 INT170653 Ngf Regulation of Csf2 1 0.34 1.11 1.05
102 INT76001 Ngf Positive_regulation of Ngfr 1 0.16 0.93 1.05
103 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04
104 INT180806 Ngf Positive_regulation of Regulation of Sorbs1 1 0.03 0.28 1.04
105 INT335401 Hgf Positive_regulation of Ngf 1 0.30 1.13 1.04
106 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
107 INT151768 Ngf Positive_regulation of P2rx6 1 0.00 0.81 1.01
108 INT137441 Ngf Negative_regulation of Sema3a 1 0.46 2.07 1.01
109 INT151765 Ngf Positive_regulation of Positive_regulation of P2rx6 1 0.00 0.81 1.01
110 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
111 INT83987 Ngf Regulation of Atf2 1 0.52 0.49 1
112 INT86662 Ngf Regulation of SCN10A 1 0.27 1.24 0.99
113 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
114 INT40424 CCK Regulation of Localization of INS 1 0.02 0 0.97
115 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
116 INT180780 Ngf Regulation of Gdnf 1 0.22 0.28 0.96
117 INT271409 NGF Positive_regulation of TRPV1 1 0.08 2.45 0.94
118 INT271410 NGF Positive_regulation of Gene_expression of TRPV1 1 0.07 2.45 0.94
119 INT70803 Ngf Regulation of Tac4 1 0.06 0.39 0.93
120 INT70802 Ngf Regulation of Ppt1 1 0.21 0.39 0.93
121 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92
122 INT127673 NGF Regulation of Gene_expression of NTRK1 1 0.48 2.12 0.92
123 INT138602 Negative_regulation of BCL2L2 Positive_regulation of F2 1 0.00 0.67 0.92
124 INT138601 BCL2L2 Positive_regulation of F2 1 0.00 0.66 0.91
125 INT13282 Fgf2 Regulation of Ngf 1 0.66 0.21 0.91
126 INT13280 Ngf Regulation of Fgf2 1 0.48 0.2 0.9
127 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
128 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
129 INT164677 Ngf Positive_regulation of Gene_expression of Fos 1 0.52 0.08 0.89
130 INT84369 Ngf Positive_regulation of KNG1 1 0.04 0.29 0.89
131 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
132 INT165540 NGF Positive_regulation of GRIN1 1 0.07 0.17 0.88
133 INT297463 Binding of Ntrk1 and Ngf 1 0.10 0.78 0.87
134 INT251704 Ache Regulation of Gene_expression of Acot1 1 0.08 1.68 0.87
135 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
136 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85
137 INT340437 Binding of SERPINH1 and HLA-DRB4 1 0.00 2.26 0.84
138 INT129881 Binding of Calr and Cbll1 1 0.00 0.58 0.84
139 INT140447 Ngf Regulation of Scn9a 1 0.69 0.16 0.84
140 INT174509 Binding of CD4 and CD28 1 0.26 1.68 0.84
141 INT12137 Ngf Regulation of Gad1 1 0.27 0.67 0.83
142 INT113250 Olr1259 Negative_regulation of Ache 1 0.01 0.38 0.83
143 INT145777 Ngf Regulation of Localization of Qrfp 1 0.05 0.35 0.82
144 INT107246 Ngf Regulation of Transcription of ASIC1 1 0.01 0.57 0.81
145 INT131463 NTRK1 Regulation of Localization of INS 1 0.41 0.63 0.8
146 INT53199 Positive_regulation of Cd4 Positive_regulation of Gene_expression of Il2 1 0.52 0.72 0.8
147 INT274785 S100B Positive_regulation of Ngf 1 0.05 0.61 0.8
148 INT80200 Negative_regulation of Ngf Negative_regulation of Gene_expression of Rab38 1 0.01 0.68 0.8
149 INT140921 Btnl2 Negative_regulation of Cd4 1 0.01 0.88 0.8
150 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79
151 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
152 INT21233 Ngf Regulation of Fgf1 1 0.46 0.09 0.79
153 INT42796 Ngf Positive_regulation of Binding of Penk 1 0.56 0.08 0.79
154 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
155 INT103335 Ngf Regulation of TRPV1 1 0.05 0.53 0.77
156 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
157 INT46246 Tpsg1 Regulation of Ache 1 0.15 0.06 0.76
158 INT46247 Tpsg1 Regulation of Binding of Ache 1 0.15 0.06 0.76
159 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
160 INT106691 Ngf Positive_regulation of SIGMAR1 1 0.04 0 0.74
161 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
162 INT41165 Gtf3a Regulation of INS 1 0.00 0.15 0.74
163 INT298730 PROC Positive_regulation of Gene_expression of Ngf 1 0.00 0.6 0.74
164 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
165 INT18447 Binding of Ache and Chat 2 0.33 0.33 0.73
166 INT31642 POMC Regulation of GCG 1 0.41 0.62 0.73
167 INT41164 Binding of INS and SST 1 0.07 0.14 0.73
168 INT31643 POMC Regulation of INS 1 0.59 0.62 0.73
169 INT113552 Binding of PLAU and PLAUR 4 0.31 3.09 0.72
170 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72
171 INT106999 F2 Positive_regulation of PAR4 3 0.06 1.83 0.72
172 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
173 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
174 INT163946 Binding of ERAP1 and Il23r 1 0.23 0.56 0.72
175 INT180769 Calca Regulation of Binding of Ngf 1 0.40 0.15 0.72
176 INT161946 Alk Negative_regulation of Localization of Ngf 1 0.10 1.01 0.72
177 INT180776 Regulation of Ngf Positive_regulation of Trpv1 1 0.28 0.59 0.72
178 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71
179 INT102123 Ngf Regulation of Gene_expression of Cnr1 1 0.53 0.42 0.71
180 INT160711 Binding of KIR3DL1 and ERAP1 1 0.15 0.71 0.71
181 INT274786 Ngf Positive_regulation of Gene_expression of S100B 1 0.05 0.63 0.71
182 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71
183 INT224580 Gene_expression of IL18 Positive_regulation of SERPINH1 1 0.00 1.34 0.7
184 INT82021 Negative_regulation of Binding of Ngfr and Ngf 1 0.29 0.32 0.69
185 INT126781 Binding of F10 and Serpinc1 1 0.00 1.51 0.69
186 INT82022 Binding of Trib3 and Ngf 1 0.08 0.31 0.68
187 INT82020 Negative_regulation of Binding of Trib3 and Ngf 1 0.07 0.31 0.68
188 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
189 INT118979 NGF Positive_regulation of Phosphorylation of NTRK1 1 0.56 0.67 0.67
190 INT93615 Ngf Positive_regulation of Lilrb4 1 0.06 0.75 0.67
191 INT150338 Binding of F2 and F2R 1 0.11 0.4 0.67
192 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64
193 INT96475 Ngf Positive_regulation of Gene_expression of TRPV1 1 0.03 0.22 0.63
194 INT174500 Positive_regulation of Binding of CD4 and HLA-B 1 0.21 2.33 0.63
195 INT122773 Ngf Negative_regulation of Gene_expression of Trpv1 1 0.45 0.8 0.62
196 INT222492 Ngf Positive_regulation of Gene_expression of Prl 1 0.24 0 0.62
197 INT71942 Negative_regulation of PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.62
198 INT30902 GCG Positive_regulation of Localization of SST 1 0.11 0.05 0.62
199 INT252859 Binding of Ngf and Trpa1 1 0.19 0.84 0.62
200 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62

Single Events

The table below shows the top 100 pain related interactions that have been reported for endoplasmic reticulum lumen. They are ordered first by their pain relevance and then by number of times they were reported in endoplasmic reticulum lumen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
2 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
3 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
4 INT812 Localization of INS 1026 0.81 515.6 145.31
5 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
6 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
7 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
8 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
9 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
10 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
11 INT3034 Localization of Ngf 126 0.81 50.81 72.84
12 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4
13 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27
14 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
15 INT251 Regulation of INS 398 0.62 232.47 55.04
16 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
17 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
18 INT19078 Binding of Ngf 78 0.48 31.03 44.33
19 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74
20 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
21 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46
22 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
23 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
24 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05
25 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16
26 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28
27 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11
28 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89
29 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75
30 INT276 Regulation of Ache 83 0.62 16.75 25.99
31 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85
32 INT17625 Localization of GCG 210 0.80 55.69 24.97
33 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38
34 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31
35 INT4535 Localization of PROC 106 0.73 76.24 21.1
36 INT17848 Binding of PTGS2 70 0.46 32.1 20.6
37 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03
38 INT64261 Negative_regulation of Positive_regulation of Ngf 21 0.59 16.28 19.78
39 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51
40 INT49922 Positive_regulation of Positive_regulation of Ngf 21 0.67 14.46 17.68
41 INT1767 Positive_regulation of PROC 83 0.67 54.14 17
42 INT15358 Transcription of Ngf 29 0.72 10.43 16.94
43 INT20216 Localization of NGF 40 0.80 18.16 16.61
44 INT84924 Positive_regulation of Gene_expression of NGF 29 0.68 17.91 16.46
45 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43
46 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4
47 INT19071 Localization of Ache 66 0.81 5.1 16.27
48 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73
49 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89
50 INT71150 Binding of NGF 22 0.46 13.67 14.81
51 INT14572 Binding of INS 205 0.48 175.43 13.38
52 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
53 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79
54 INT52905 Gene_expression of Cd4 84 0.78 45.68 12.75
55 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
56 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39
57 INT36287 Binding of CD4 96 0.47 58.93 11.88
58 INT60590 Positive_regulation of Gbf1 25 0.39 12.5 11.79
59 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
60 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
61 INT85048 Regulation of NGF 19 0.62 11.61 10.5
62 INT244490 Gene_expression of HSP90B1 4 0.33 41.16 10.37
63 INT16404 Regulation of CD4 54 0.61 33.05 10.29
64 INT1252 Binding of Ache 46 0.48 9.94 10.25
65 INT4494 Regulation of GCG 41 0.45 18.38 9.68
66 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53
67 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48
68 INT2976 Regulation of Bche 29 0.45 8.56 9.42
69 INT75997 Positive_regulation of Localization of Ngf 14 0.69 7.78 9.41
70 INT1168 Binding of PROC 62 0.38 44.15 9.04
71 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04
72 INT4534 Regulation of PROC 38 0.33 19.81 8.99
73 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62
74 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51
75 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44
76 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
77 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35
78 INT846 Positive_regulation of B2M 42 0.70 29.78 8.06
79 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53
80 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53
81 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51
82 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24
83 INT63373 Negative_regulation of Gene_expression of NGF 14 0.57 8.9 7.1
84 INT49761 Regulation of Positive_regulation of Ngf 6 0.62 3.83 7.1
85 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
86 INT17049 Localization of CD4 57 0.75 35.33 6.89
87 INT160562 Localization of Cd4 49 0.71 27.58 6.78
88 INT50255 Regulation of Cd4 39 0.49 29.73 6.77
89 INT17618 Gene_expression of B2M 36 0.66 16.39 6.68
90 INT9818 Positive_regulation of Pdia4 12 0.34 0.67 6.65
91 INT90097 Localization of PTGS2 15 0.69 6.14 6.63
92 INT13139 Negative_regulation of Cd4 27 0.47 17.49 6.61
93 INT4060 Gene_expression of Bche 17 0.70 5.23 6.59
94 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52
95 INT63374 Regulation of Gene_expression of NGF 12 0.45 5.6 6.4
96 INT67656 Positive_regulation of Positive_regulation of PTGS2 12 0.46 4.83 6.17
97 INT15528 Positive_regulation of GCG 38 0.63 20.47 6.14
98 INT117621 Positive_regulation of HSPA5 17 0.59 13.26 6.06
99 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96
100 INT53196 Binding of Cd4 44 0.47 27.28 5.85
101 INT62611 Phosphorylation of Ngf 13 0.82 1.12 5.8
102 INT49701 Negative_regulation of Localization of Ngf 9 0.58 3.01 5.75
103 INT31227 Regulation of Localization of GCG 28 0.48 4.86 5.72
104 INT16262 Positive_regulation of Transcription of Ngf 8 0.50 4.02 5.48
105 INT19072 Regulation of Gene_expression of Ache 14 0.62 2.74 5.29
106 INT95131 Binding of Cd4 27 0.37 21.62 5.07
107 INT152742 Positive_regulation of Localization of NGF 7 0.50 4.44 5.02
108 INT71418 Binding of CES1 42 0.40 29.78 5.01
109 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98
110 INT20059 Protein_catabolism of Ache 15 0.98 3.73 4.87
111 INT10694 Binding of Bche 19 0.48 8.03 4.85
112 INT26583 Positive_regulation of Cd4 40 0.54 21.96 4.83
113 INT15474 Gene_expression of PLAUR 36 0.75 22.32 4.63
114 INT14502 Gene_expression of BCHE 40 0.67 18.52 4.6
115 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58
116 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5
117 INT9842 Binding of F2 36 0.47 22.79 4.42
118 INT35609 Negative_regulation of F10 37 0.57 17.15 4.41
119 INT46121 Negative_regulation of SERPINH1 14 0.38 10.84 4.41
120 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
121 INT11946 Transcription of Ache 18 0.69 2.62 4.13
122 INT52616 Negative_regulation of Positive_regulation of PTGS2 13 0.43 4.95 4.13
123 INT3530 Regulation of BCHE 18 0.60 5.47 4.12
124 INT17626 Positive_regulation of Localization of GCG 36 0.69 13.94 4.06
125 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
126 INT49700 Regulation of Localization of Ngf 6 0.59 1.18 3.95
127 INT137268 Regulation of Binding of Ngf 5 0.61 1.63 3.91
128 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9
129 INT6956 Gene_expression of PTGIS 29 0.76 12.1 3.8
130 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
131 INT20455 Positive_regulation of Bche 15 0.59 7.22 3.7
132 INT84925 Transcription of NGF 11 0.65 4.13 3.65
133 INT51581 Negative_regulation of Gbf1 8 0.36 3.96 3.61
134 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6
135 INT8778 Regulation of Ache 17 0.62 3.7 3.57
136 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
137 INT10586 Localization of B2M 15 0.68 8.67 3.46
138 INT65102 Regulation of Ntf4 3 0.43 0.05 3.42
139 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
140 INT14281 Gene_expression of Hspa5 44 0.63 34.19 3.31
141 INT28009 Positive_regulation of Gene_expression of Ache 15 0.70 5.46 3.26
142 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
143 INT55792 Regulation of Negative_regulation of Bche 11 0.57 1.78 3.21
144 INT8777 Positive_regulation of Ache 25 0.68 7.77 3.18
145 INT82444 Positive_regulation of Gene_expression of Cd4 10 0.47 4.36 3.12
146 INT244512 Positive_regulation of Gene_expression of HSP90B1 2 0.30 12.08 3.12
147 INT6063 Positive_regulation of Bche 17 0.66 6.07 3.08
148 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91
149 INT159709 Binding of ERAP1 12 0.47 3.42 2.91
150 INT32623 Negative_regulation of Regulation of INS 16 0.43 10.96 2.9
151 INT22069 Positive_regulation of Localization of Ache 9 0.70 0.61 2.9
152 INT195978 Gene_expression of Hsp90b1 26 0.65 11.28 2.88
153 INT130700 Gene_expression of HSPA5 16 0.75 11.55 2.81
154 INT68505 Positive_regulation of Negative_regulation of PTGS2 8 0.49 2.26 2.76
155 INT130702 Positive_regulation of Gene_expression of HSPA5 7 0.59 7.53 2.68
156 INT14447 Localization of F2 20 0.79 12.77 2.67
157 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
158 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64
159 INT11892 Gene_expression of ACHE 10 0.68 1.32 2.63
160 INT19492 Regulation of B2M 16 0.60 10.97 2.55
161 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
162 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53
163 INT39560 Positive_regulation of F10 25 0.67 10.67 2.5
164 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
165 INT82072 Positive_regulation of Ntf4 5 0.41 1.05 2.49
166 INT16672 Negative_regulation of MBTPS1 6 0.26 1.45 2.46
167 INT1864 Regulation of Bche 18 0.47 6.18 2.44
168 INT41549 Positive_regulation of Localization of B2M 5 0.59 4.26 2.42
169 INT54555 Negative_regulation of CALR 10 0.41 4.41 2.4
170 INT27338 Regulation of ACHE 6 0.62 1.25 2.38
171 INT87319 Regulation of Negative_regulation of Ngf 3 0.61 2.4 2.38
172 INT99157 Binding of SIL1 8 0.35 2.66 2.33
173 INT3315 Negative_regulation of Positive_regulation of INS 31 0.57 14.73 2.27
174 INT30202 Positive_regulation of GHRL 5 0.44 3.04 2.22
175 INT14890 Localization of ACHE 5 0.80 0.47 2.21
176 INT26177 Regulation of Regulation of INS 19 0.44 11.32 2.18
177 INT2570 Negative_regulation of Gene_expression of Ache 13 0.43 2.88 2.18
178 INT16461 Negative_regulation of Gene_expression of PROC 13 0.24 4.39 2.17
179 INT35058 Positive_regulation of PLAUR 11 0.61 7.21 2.16
180 INT52072 Negative_regulation of Ces1c 6 0.31 1.37 2.13
181 INT17747 Regulation of Cd4 14 0.41 10.02 2.12
182 INT62612 Negative_regulation of Transcription of Ngf 5 0.43 1.33 2.1
183 INT9840 Positive_regulation of F7 17 0.57 17.83 2.08
184 INT63375 Positive_regulation of Positive_regulation of NGF 2 0.48 1.17 2.08
185 INT82069 Gene_expression of Ntf4 5 0.47 1.92 2.07
186 INT195968 Positive_regulation of Gene_expression of Hsp90b1 10 0.49 5.21 2.02
187 INT161121 Binding of Erap1 2 0.48 1.99 1.99
188 INT97579 Negative_regulation of Localization of PTGS2 2 0.08 2.37 1.99
189 INT70526 Binding of CALR 11 0.35 7.09 1.97
190 INT21941 Regulation of CALR 7 0.53 3.88 1.96
191 INT5415 Negative_regulation of Pdia4 6 0.36 0.94 1.93
192 INT99970 Regulation of Binding of NGF 2 0.27 2.35 1.93
193 INT21782 Negative_regulation of B2M 11 0.46 5.49 1.92
194 INT12895 Negative_regulation of Positive_regulation of Pdia4 2 0.14 0 1.91
195 INT55962 Positive_regulation of Localization of PROC 9 0.20 7.76 1.87
196 INT60588 Negative_regulation of Positive_regulation of Gbf1 3 0.36 0.67 1.87
197 INT20094 Binding of Pdia3 3 0.31 1.26 1.87
198 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
199 INT3866 Positive_regulation of Positive_regulation of INS 30 0.59 21.58 1.86
200 INT14503 Binding of BCHE 13 0.48 3.95 1.85
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