GO:0005813

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Name centrosome
Categary Component
Go Slim No
Go Link GO:0005813
Unique Molecular Interactions 1394
Total Molecular Interactions 1982
Total Single Events 12252
Pain Genes Associated 171

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for centrosome. They are ordered first by their pain relevance and then by number of times they were reported for centrosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT32911 Binding of Insrr and Rbm39 2 0.00 0 3.95
2 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
3 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
4 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
5 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
6 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85
7 INT32656 Pomc Positive_regulation of Rbm39 1 0.08 0.42 2.84
8 INT229497 Binding of Vim and Ndel1 1 0.33 3.5 2.81
9 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
10 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
11 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
12 INT6320 Binding of Rbm39 and Scq1 1 0.03 0 1.92
13 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
14 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
15 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
16 INT169346 Nxn Negative_regulation of Dynll1 1 0.06 1.22 1.87
17 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
18 INT104710 Em Positive_regulation of Rbm39 1 0.02 0.07 1.76
19 INT104709 Msh3 Positive_regulation of Rbm39 1 0.01 0.07 1.76
20 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
21 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
22 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
23 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64
24 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
25 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
26 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
27 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
28 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
29 INT32657 Positive_regulation of Pomc Positive_regulation of Rbm39 1 0.08 0.22 1.51
30 INT29093 Binding of H2-Ab1 and Rbm39 1 0.06 0 1.5
31 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5
32 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
33 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
34 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
35 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
36 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
37 INT93388 Rbm39 Positive_regulation of Positive_regulation of Pdyn 1 0.03 0.32 1.4
38 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
39 INT229496 Binding of Ndel1 and Gopc 1 0.08 2.05 1.36
40 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
41 INT145473 Mastl Positive_regulation of Dnahc8 1 0.07 0.06 1.33
42 INT68071 Binding of Tic1 and Rbm39 1 0.01 2.54 1.33
43 INT126831 Binding of Oprk1 and Rbm39 1 0.05 0.88 1.33
44 INT59446 Rbm39 Positive_regulation of Negative_regulation of Pomc 1 0.03 0.19 1.32
45 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
46 INT198957 Binding of Cnr1 and Mastl 1 0.00 0 1.31
47 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3
48 INT124926 Negative_regulation of Prkaca Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
49 INT85742 Pdyn Positive_regulation of Rbm39 1 0.01 0.17 1.29
50 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
51 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
52 INT132943 Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
53 INT132944 Positive_regulation of Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
54 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
55 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
56 INT73710 Mastl Positive_regulation of Localization of Oprl1 1 0.02 0 1.26
57 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
58 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
59 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
60 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
61 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
62 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17
63 INT146352 Binding of Rgs14 and Mors1 1 0.23 0.27 1.17
64 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
65 INT85744 Binding of Pdyn and Rbm39 1 0.01 0.16 1.12
66 INT269200 Prkaca Positive_regulation of Phosphorylation of Ceacam3 1 0.03 0.65 1.09
67 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
68 INT96906 Plxna3 Regulation of Regulation of Prkaca 1 0.17 0.71 1.08
69 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
70 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 1 0.40 0 1.05
71 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
72 INT97011 Binding of CALM3 and OPRM1 1 0.35 0 1.05
73 INT180806 Ngf Positive_regulation of Regulation of Sorbs1 1 0.03 0.28 1.04
74 INT231391 Binding of Lpar1 and Rbm39 1 0.00 1.04 1.04
75 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
76 INT98555 Oprm1 Positive_regulation of Casp8 1 0.51 0.36 1.02
77 INT240453 Prkcg Positive_regulation of Positive_regulation of Prkaca 1 0.23 0.63 1.01
78 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
79 INT240455 Ephb1 Positive_regulation of Positive_regulation of Prkaca 1 0.22 0.63 1.01
80 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
81 INT320021 Prkaca Regulation of Positive_regulation of Kcnma1 1 0.00 0.54 1
82 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1
83 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99
84 INT276864 Positive_regulation of Gpr65 Positive_regulation of Prkaca 1 0.16 0.74 0.97
85 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96
86 INT180803 Sorbs1 Regulation of Gdnf 1 0.01 0.28 0.95
87 INT252877 Prkaca Positive_regulation of Regulation of Grip2 1 0.01 0.22 0.94
88 INT252878 Prkaca Regulation of Regulation of Grip2 1 0.01 0.22 0.94
89 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
90 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92
91 INT195927 Binding of Prkaca and Trpv1 1 0.07 0.28 0.92
92 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9
93 INT54200 Gnai1 Negative_regulation of Pag1 1 0.05 0.18 0.9
94 INT54197 Binding of Gnai1 and Pag1 1 0.04 0.18 0.9
95 INT54854 Sorbs1 Regulation of Ins1 1 0.34 0.23 0.9
96 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89
97 INT151961 Rbm39 Positive_regulation of Insrr 1 0.17 0.26 0.89
98 INT59482 Cpe Positive_regulation of Rbm39 1 0.02 0 0.89
99 INT151630 Il1rn Negative_regulation of Dock9 1 0.03 1.33 0.88
100 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
101 INT224583 CSF2 Positive_regulation of IL1RN 1 0.02 1.3 0.88
102 INT196834 Prkaca Positive_regulation of Phosphorylation of Ppp1r1b 2 0.15 0 0.87
103 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87
104 INT139594 Binding of Nts and Rbm39 1 0.02 0.19 0.87
105 INT112914 Ppp1r1b Negative_regulation of Prkaca 3 0.22 0.13 0.86
106 INT133176 Regulation of Mastl Negative_regulation of Il12a 1 0.01 0.24 0.86
107 INT133177 Mastl Negative_regulation of Il12a 1 0.01 0.24 0.86
108 INT149925 Negative_regulation of Cpox Negative_regulation of Gene_expression of Pde4d 1 0.01 0.39 0.84
109 INT353719 Rbm39 Regulation of Localization of Vta1 1 0.01 0 0.84
110 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
111 INT97056 Cpz Regulation of Gene_expression of Bcl2l1 1 0.22 0.57 0.83
112 INT185937 NOS2 Regulation of Prkaca 1 0.03 1.08 0.82
113 INT78972 Prkaca Regulation of Ina 1 0.11 0.09 0.82
114 INT187226 Vip Positive_regulation of Gene_expression of Il1rn 1 0.04 0.96 0.82
115 INT190868 Binding of Marcks and Ltp 1 0.01 0.87 0.81
116 INT103178 Mastl Positive_regulation of Localization of Calca 1 0.13 0.36 0.81
117 INT40610 Binding of Prkaca and Oprl1 1 0.02 0.09 0.8
118 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
119 INT117909 Mastl Positive_regulation of Mapk1 1 0.04 0 0.79
120 INT139593 Ntsr1 Positive_regulation of Rbm39 1 0.01 0.17 0.79
121 INT296299 Positive_regulation of Cysltr1 Positive_regulation of Positive_regulation of Rbm39 1 0.00 0.59 0.79
122 INT240454 Ephb1 Regulation of Prkaca 1 0.14 0.51 0.79
123 INT296279 Positive_regulation of Rbm39 Positive_regulation of Positive_regulation of Car2 1 0.01 0.58 0.78
124 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
125 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77
126 INT231388 Pla2g4a Regulation of Pla2g6 1 0.08 0.92 0.77
127 INT341816 Binding of CEP68 and Aia1 1 0.02 4.76 0.76
128 INT91239 Prkaca Regulation of Negative_regulation of Oprm1 1 0.43 0 0.76
129 INT69692 Helt Regulation of Prkaca 1 0.00 0.33 0.76
130 INT353718 Binding of Rbm39 and Ghsr 1 0.01 0 0.76
131 INT31776 Positive_regulation of Gclc Positive_regulation of G6pd 1 0.29 0.19 0.75
132 INT139893 Binding of Alb and Alms1 1 0.04 0.48 0.75
133 INT309735 Binding of CALM3 and TRPV4 1 0.14 0 0.75
134 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75
135 INT196799 Prkaca Positive_regulation of Phosphorylation of Trh 1 0.02 0 0.74
136 INT327712 Binding of Comt and Rbm39 1 0.00 0.27 0.74
137 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73
138 INT244025 Prkaca Regulation of Phosphorylation of Gabrg1 1 0.08 0.18 0.72
139 INT351350 Prkaca Regulation of Lpar1 1 0.04 0.58 0.72
140 INT107933 Oprm1 Positive_regulation of Gene_expression of Mastl 1 0.33 0.61 0.71
141 INT73838 IGHD4-4 Positive_regulation of CDC42BPG 1 0.00 0 0.71
142 INT148449 Gene_expression of Inhbe Positive_regulation of Prkaca 1 0.05 0.68 0.71
143 INT161297 Ppp1r1b Negative_regulation of Prkaca 1 0.10 0.16 0.7
144 INT186162 Phosphorylation of Prkaca Positive_regulation of Phosphorylation of Prkcg 1 0.04 0.22 0.7
145 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
146 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7
147 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
148 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
149 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
150 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
151 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
152 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
153 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
154 INT229085 IL1RN Negative_regulation of Positive_regulation of IL1R1 1 0.12 1.72 0.68
155 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
156 INT180805 Bdnf Regulation of Sorbs1 1 0.01 0.14 0.67
157 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
158 INT115764 Binding of Rbm39 and Tat 1 0.00 0 0.66
159 INT213895 Mastl Regulation of Gene_expression of Cnr1 1 0.17 0.26 0.66
160 INT353722 Rbm39 Positive_regulation of Localization of Ghrl 1 0.01 0 0.65
161 INT92872 SON Positive_regulation of IL1RN 1 0.06 0.64 0.65
162 INT150754 GTS Negative_regulation of Gene_expression of Prkaca 1 0.32 0.08 0.65
163 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64
164 INT104858 Prkaca Negative_regulation of Negative_regulation of TRPV1 2 0.10 0.41 0.64
165 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
166 INT102863 Prkaca Regulation of Srgn 1 0.50 0.05 0.64
167 INT153796 NUBPL Negative_regulation of YWHAQ 1 0.02 0.69 0.64
168 INT83800 Aap Regulation of Gene_expression of Bcl2l1 1 0.28 0.58 0.64
169 INT281081 Prkaca Positive_regulation of Gene_expression of Adcy1 1 0.12 0 0.63
170 INT279398 Binding of IL1RN and Il1rn 1 0.00 0.51 0.63
171 INT255994 Binding of Ang and Il1rn 1 0.09 1.21 0.63
172 INT334594 Binding of GNAI1 and MRGPRD 1 0.01 0.19 0.63
173 INT255997 Binding of Il1rn and H7 1 0.01 1.21 0.63
174 INT281078 Prkacb Positive_regulation of Gene_expression of Adcy1 1 0.03 0 0.63
175 INT281090 Prkacb Positive_regulation of Mapk1 1 0.06 0 0.62
176 INT281091 Prkacb Positive_regulation of Mdk 1 0.02 0 0.62
177 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
178 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61
179 INT324065 Ptger2 Positive_regulation of Prkaca 2 0.24 0.63 0.61
180 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61
181 INT281086 Prkaca Positive_regulation of Mdk 1 0.08 0 0.61
182 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
183 INT29803 Binding of Rtcd1 and Rbm39 1 0.00 0.14 0.59
184 INT77376 Tmie Negative_regulation of Mastl 1 0.01 0 0.59
185 INT144320 Binding of Fst and Rbm39 1 0.04 0 0.59
186 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
187 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
188 INT244055 Prkaca Regulation of Gabrg1 1 0.08 0 0.58
189 INT102864 Prkaca Regulation of Twist1 1 0.48 0.05 0.58
190 INT350699 Binding of Casp8 and Stat3 1 0.04 1.81 0.58
191 INT350716 Binding of CD58 and Casp8 1 0.03 1.81 0.58
192 INT118001 Csk Regulation of Trpv1 1 0.08 0.09 0.58
193 INT356320 ORF61 Positive_regulation of Positive_regulation of Prkaca 1 0.01 0.05 0.57
194 INT145617 Ngf Positive_regulation of Gene_expression of Fez1 1 0.43 0.57 0.57
195 INT296472 Camk2a Positive_regulation of Prkaca 1 0.09 0.32 0.57
196 INT296456 Gria1 Negative_regulation of Rbm39 1 0.00 0.45 0.57
197 INT85487 IL1RN Negative_regulation of IL1R1 1 0.02 0 0.57
198 INT143938 Il1rn Negative_regulation of Il1b 1 0.04 0.52 0.57
199 INT143940 Il1rn Negative_regulation of Il1f5 1 0.00 0.51 0.57
200 INT98245 Binding of Oprm1 and Rbm39 1 0.01 0 0.57

Single Events

The table below shows the top 100 pain related interactions that have been reported for centrosome. They are ordered first by their pain relevance and then by number of times they were reported in centrosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16
2 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28
3 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
4 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77
5 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
6 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44
7 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62
8 INT5770 Binding of Rbm39 88 0.41 13.23 55.5
9 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38
10 INT1163 Negative_regulation of Rbm39 64 0.29 16.8 34.74
11 INT89055 Phosphorylation of Prkaca 60 0.61 13.41 32.49
12 INT15296 Regulation of Rbm39 45 0.29 10.66 29.27
13 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96
14 INT10929 Positive_regulation of FLII 46 0.67 13.17 24.63
15 INT96904 Regulation of Prkaca 33 0.44 10.86 24.51
16 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39
17 INT89805 Gene_expression of Prkaca 45 0.77 11.03 20.77
18 INT292049 Gene_expression of Csnk1a1 1 0.59 28.22 19.53
19 INT33542 Gene_expression of Il1rn 41 0.76 32.47 18.08
20 INT10555 Gene_expression of FLII 37 0.75 7.81 17.6
21 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93
22 INT6480 Positive_regulation of IL1RN 59 0.69 33.7 16.66
23 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
24 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
25 INT49606 Gene_expression of Il1rn 30 0.66 15.78 14.82
26 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
27 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13
28 INT36177 Binding of Alms1 70 0.31 35.47 13.81
29 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68
30 INT72565 Localization of IL1RN 45 0.80 23.59 13.17
31 INT74838 Positive_regulation of Sorbs1 18 0.34 6.93 12.63
32 INT35801 Regulation of Alms1 34 0.38 20.88 12.38
33 INT8533 Regulation of Sorbs1 9 0.27 3.01 11.98
34 INT87844 Binding of IL1RN 40 0.41 24.37 11.92
35 INT78970 Positive_regulation of Positive_regulation of Prkaca 14 0.47 3.06 11.49
36 INT52625 Regulation of IL1RN 30 0.61 19.12 11.31
37 INT6474 Positive_regulation of Gene_expression of IL1RN 34 0.69 21.87 10.99
38 INT118390 Positive_regulation of Nfe2l2 82 0.70 20.41 10.61
39 INT790 Gene_expression of Mastl 22 0.68 4.56 10.23
40 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
41 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08
42 INT5791 Positive_regulation of Positive_regulation of Rbm39 13 0.25 1.61 9.88
43 INT29802 Localization of Rbm39 18 0.64 4.04 9.84
44 INT102964 Phosphorylation of Rbm39 23 0.04 5.58 9.83
45 INT66382 Positive_regulation of Phosphorylation of Prkaca 33 0.49 7.05 9.69
46 INT62254 Negative_regulation of FLII 20 0.48 4.11 9.44
47 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
48 INT40609 Binding of Prkaca 23 0.36 3.42 9.19
49 INT8535 Localization of Sorbs1 9 0.80 2.71 9.07
50 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
51 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85
52 INT71478 Positive_regulation of Positive_regulation of Prkaca 21 0.37 5.14 8.85
53 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
54 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
55 INT72539 Gene_expression of Sorbs1 10 0.78 4.98 8.14
56 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1
57 INT142526 Positive_regulation of Gene_expression of Prkaca 12 0.46 2.48 8.05
58 INT57176 Positive_regulation of Dynll1 9 0.49 4.76 7.71
59 INT5409 Negative_regulation of G6pd 33 0.57 29.21 7.64
60 INT13348 Negative_regulation of Mastl 11 0.36 3.33 7.28
61 INT74099 Negative_regulation of Dynll1 8 0.56 3.43 7.25
62 INT10478 Protein_catabolism of Alms1 25 0.47 12.95 7.19
63 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
64 INT89052 Positive_regulation of Phosphorylation of Prkaca 13 0.37 2.92 7.05
65 INT68466 Negative_regulation of Positive_regulation of Prkaca 6 0.57 2.29 6.83
66 INT73709 Binding of Mastl 11 0.40 3.39 6.76
67 INT69980 Negative_regulation of Il1rn 11 0.33 7.75 6.7
68 INT292062 Negative_regulation of Csnk1a1 1 0.44 7.57 6.52
69 INT38807 Negative_regulation of PLA2G6 29 0.59 10.1 6.42
70 INT126395 Positive_regulation of Gene_expression of Il1rn 11 0.41 7.66 6.25
71 INT73902 Regulation of Gene_expression of IL1RN 6 0.61 4.59 6.14
72 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
73 INT20899 Negative_regulation of GNAI1 12 0.57 4.24 6.07
74 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
75 INT1493 Positive_regulation of Prkacb 8 0.59 2.75 5.99
76 INT107441 Positive_regulation of Gene_expression of Il1rn 7 0.46 3.24 5.95
77 INT118388 Localization of Nfe2l2 40 0.81 9.59 5.89
78 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
79 INT97018 Binding of CALM3 7 0.43 0.13 5.82
80 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
81 INT85777 Regulation of Negative_regulation of Prkaca 7 0.46 1.85 5.76
82 INT66549 Negative_regulation of Positive_regulation of FLII 9 0.36 3.08 5.74
83 INT15542 Negative_regulation of CASP8 20 0.41 17.3 5.63
84 INT71477 Negative_regulation of Positive_regulation of Prkaca 10 0.37 1.69 5.57
85 INT114180 Negative_regulation of Il1rn 22 0.57 11.06 5.44
86 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
87 INT292072 Positive_regulation of Gene_expression of Csnk1a1 1 0.53 9.76 5.39
88 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32
89 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
90 INT105775 Gene_expression of Pde4d 31 0.78 4.18 5.21
91 INT106667 Gene_expression of NDRG1 18 0.70 9.96 5.14
92 INT109150 Negative_regulation of Tubgcp2 4 0.38 2.04 5.12
93 INT5411 Positive_regulation of G6pd 20 0.70 4.74 5.11
94 INT55634 Negative_regulation of Gene_expression of FLII 7 0.41 1.77 5.11
95 INT139162 Localization of Marcks 1 0.34 0 5.1
96 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
97 INT73905 Transcription of IL1RN 10 0.71 9.16 5.04
98 INT29893 Negative_regulation of Prkacb 4 0.37 1.14 5.04
99 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
100 INT71244 Binding of Prkaca 8 0.30 2.64 4.96
101 INT14018 Negative_regulation of Binding of Rbm39 6 0.31 1.84 4.93
102 INT114183 Positive_regulation of Il1rn 17 0.55 11.31 4.83
103 INT87156 Phosphorylation of Marcks 8 0.40 2.48 4.8
104 INT62920 Regulation of Gnai1 3 0.52 0.08 4.78
105 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
106 INT92199 Negative_regulation of Gene_expression of IL1RN 14 0.58 10.11 4.71
107 INT17391 Gene_expression of GNAI1 11 0.75 5.26 4.7
108 INT81485 Negative_regulation of IL1RN 19 0.57 8.3 4.69
109 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
110 INT17393 Positive_regulation of GNAI1 17 0.49 2.42 4.66
111 INT72538 Negative_regulation of Sorbs1 7 0.59 4.49 4.61
112 INT131808 Localization of Apex1 2 0.16 13.46 4.61
113 INT292060 Positive_regulation of Csnk1a1 1 0.53 6.03 4.57
114 INT29326 Gene_expression of Calm1 17 0.67 3.71 4.53
115 INT1490 Regulation of Prkacb 7 0.21 0.5 4.52
116 INT2213 Regulation of EP300 10 0.54 4.72 4.5
117 INT76683 Positive_regulation of Il1rn 9 0.51 9.3 4.41
118 INT74393 Gene_expression of Dynll1 8 0.65 2.64 4.39
119 INT108354 Negative_regulation of Phosphorylation of Prkaca 18 0.41 6.24 4.37
120 INT34263 Positive_regulation of Mastl 8 0.35 1.36 4.35
121 INT292057 Regulation of Csnk1a1 1 0.34 3.52 4.33
122 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28
123 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
124 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
125 INT83798 Negative_regulation of Gene_expression of Bcl2l1 28 0.58 20.26 4.21
126 INT119544 Gene_expression of Nfe2l2 50 0.77 19.32 4.19
127 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
128 INT83796 Regulation of Gene_expression of Bcl2l1 10 0.61 7.85 4.05
129 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96
130 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95
131 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
132 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
133 INT120742 Negative_regulation of Gene_expression of Prkaca 6 0.24 3.76 3.86
134 INT190858 Phosphorylation of Marcks 1 0.33 6.29 3.86
135 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
136 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82
137 INT95423 Negative_regulation of Bcl2l1 26 0.41 21.66 3.81
138 INT63121 Binding of APC 29 0.41 23.02 3.8
139 INT86769 Positive_regulation of Gene_expression of Rbm39 11 0.25 5.6 3.8
140 INT1167 Regulation of Mastl 7 0.53 1.86 3.77
141 INT146350 Phosphorylation of Rgs14 1 0.80 0.79 3.77
142 INT108761 Localization of Alms1 24 0.70 13.92 3.74
143 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
144 INT8536 Binding of Sorbs1 2 0.14 1.24 3.64
145 INT116623 Localization of Prkaca 15 0.73 2.89 3.59
146 INT123564 Negative_regulation of Rock2 13 0.59 9.61 3.58
147 INT107555 Gene_expression of Marcks 8 0.58 1.22 3.56
148 INT132941 Positive_regulation of Phosphorylation of Rbm39 6 0.03 1.76 3.56
149 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
150 INT83646 Binding of Il1rn 12 0.37 4.41 3.51
151 INT169344 Positive_regulation of Gene_expression of Dynll1 3 0.49 2.34 3.48
152 INT55259 Negative_regulation of Calm2 9 0.49 1.87 3.4
153 INT40232 Transcription of Il1rn 8 0.53 9.6 3.37
154 INT118393 Positive_regulation of Localization of Nfe2l2 9 0.70 2.82 3.3
155 INT78969 Regulation of Positive_regulation of Prkaca 5 0.37 1.38 3.29
156 INT42849 Regulation of Binding of Rbm39 1 0.37 0 3.29
157 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
158 INT26312 Positive_regulation of PLA2G6 26 0.70 7.41 3.2
159 INT292056 Localization of Csnk1a1 1 0.57 3.99 3.17
160 INT37811 Negative_regulation of SERPINB6 8 0.47 4.65 3.15
161 INT171888 Binding of Il1rn 13 0.38 5.53 3.13
162 INT136651 Binding of Calm2 30 0.42 1.09 3.11
163 INT86245 Positive_regulation of Bcl2l1 15 0.46 12.67 3.11
164 INT130441 Phosphorylation of MARCKS 8 0.37 3.24 3.09
165 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
166 INT92355 Negative_regulation of Marcks 4 0.48 0 3.07
167 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
168 INT6895 Localization of Mastl 5 0.31 2.94 2.96
169 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
170 INT98554 Positive_regulation of Casp8 20 0.67 21.32 2.9
171 INT200833 Gene_expression of Ndel1 2 0.73 5.56 2.9
172 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
173 INT5412 Regulation of G6pd 9 0.62 1.64 2.87
174 INT118394 Positive_regulation of Positive_regulation of Nfe2l2 13 0.70 1.4 2.81
175 INT19985 Negative_regulation of Negative_regulation of Rbm39 4 0.16 0.99 2.79
176 INT27260 Gene_expression of DYNLL1 8 0.75 7.72 2.78
177 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71
178 INT1023 Negative_regulation of Pxk 13 0.59 0.76 2.7
179 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68
180 INT22739 Positive_regulation of DYNLL1 5 0.67 1.69 2.67
181 INT156016 Binding of BCL2L1 10 0.36 7.42 2.64
182 INT96217 Positive_regulation of Ift20 4 0.45 0.65 2.62
183 INT15543 Gene_expression of CASP8 32 0.75 25.6 2.61
184 INT69529 Positive_regulation of Localization of Rbm39 3 0.08 0.78 2.61
185 INT122060 Positive_regulation of Positive_regulation of Sorbs1 2 0.34 0.06 2.57
186 INT76679 Positive_regulation of Transcription of Il1rn 1 0.37 9.13 2.55
187 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54
188 INT120551 Negative_regulation of Rock2 8 0.52 2.73 2.53
189 INT62064 Negative_regulation of Gene_expression of Il1rn 6 0.32 4.81 2.53
190 INT79399 Gene_expression of Pde4d 6 0.70 2.83 2.51
191 INT292070 Binding of Csnk1a1 1 0.28 3.18 2.5
192 INT106668 Positive_regulation of Gene_expression of NDRG1 3 0.10 1.93 2.49
193 INT69981 Positive_regulation of Negative_regulation of Il1rn 2 0.09 3.28 2.48
194 INT107489 Negative_regulation of Pde4d 3 0.42 0 2.47
195 INT190863 Negative_regulation of Phosphorylation of Marcks 1 0.23 4.71 2.47
196 INT72013 Negative_regulation of Gnai2 5 0.35 0.09 2.44
197 INT163544 Binding of Psen1 40 0.36 15.28 2.42
198 INT74446 Positive_regulation of Dync1h1 25 0.59 13 2.38
199 INT55633 Positive_regulation of Gene_expression of FLII 5 0.42 1.54 2.32
200 INT117336 Gene_expression of Nek1 2 0.02 8.56 2.31
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