GO:0005815

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Name microtubule organizing center
Categary Component
Go Slim Yes
Go Link GO:0005815
Unique Molecular Interactions 351
Total Molecular Interactions 449
Total Single Events 3557
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for microtubule organizing center. They are ordered first by their pain relevance and then by number of times they were reported for microtubule organizing center. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
2 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
3 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
4 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
5 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
6 INT128700 BBS9 Negative_regulation of Il12a 1 0.47 0.76 1.03
7 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
8 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
9 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
10 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
11 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
12 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
13 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
14 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
15 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
16 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
17 INT188318 MCPH1 Positive_regulation of Pah 3 0.02 3 0.85
18 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85
19 INT265566 Binding of PDE4D and PTPN5 1 0.03 0.81 0.85
20 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
21 INT116803 Phosphorylation of Camk2b Positive_regulation of Camk4 1 0.03 0 0.76
22 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
23 INT116805 Phosphorylation of Camk2b Positive_regulation of Camk2a 1 0.07 0 0.76
24 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
25 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
26 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
27 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7
28 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66
29 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
30 INT62849 TUBE1 Positive_regulation of Rmp1 1 0.02 0 0.65
31 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
32 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
33 INT165844 Binding of ATF4 and HSP90AB1 1 0.15 0.34 0.61
34 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
35 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55
36 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
37 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55
38 INT147579 Binding of ATF4 and Cyp1a1 1 0.01 0.15 0.54
39 INT323146 PRKCA Positive_regulation of MAPK1 1 0.02 0 0.54
40 INT85125 IL3 Positive_regulation of MAPK1 1 0.30 0.81 0.53
41 INT85121 CSF2 Positive_regulation of MAPK1 1 0.07 0.8 0.53
42 INT85115 IL5 Positive_regulation of MAPK1 1 0.14 0.81 0.53
43 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52
44 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52
45 INT201939 CXCL10 Positive_regulation of MAPK1 1 0.11 0.72 0.52
46 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
47 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52
48 INT122872 SEMA6A Positive_regulation of MAPK1 1 0.56 0 0.52
49 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
50 INT131368 MAPK1 Positive_regulation of Bcar3 1 0.00 0.37 0.51
51 INT131369 MAPK1 Positive_regulation of Il4 1 0.01 0.37 0.51
52 INT356286 Ngf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
53 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
54 INT356279 Gdnf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
55 INT194676 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.34 0.5
56 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48
57 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
58 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
59 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
60 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47
61 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
62 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 0.11 0.77 0.46
63 INT177791 PDCD2 Positive_regulation of ATF4 1 0.06 0.76 0.46
64 INT177781 BUB1B Positive_regulation of ATF4 1 0.07 0.76 0.46
65 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
66 INT177780 BUB1B Positive_regulation of ASNS 1 0.05 0.76 0.46
67 INT117776 Binding of Ptk2 and Regulation of Phosphorylation of Ddr1 1 0.10 0.17 0.46
68 INT177787 BUB1B Positive_regulation of MTHFD2 1 0.15 0.76 0.46
69 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
70 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44
71 INT264473 Il1a Positive_regulation of Mapk1 1 0.00 0 0.43
72 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
73 INT264471 Il1a Positive_regulation of Gene_expression of Mapk1 1 0.01 0 0.43
74 INT137834 Binding of CAMK2B and CTS 1 0.05 1.38 0.42
75 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 0.11 0.39 0.42
76 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41
77 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
78 INT194705 Negative_regulation of MAPK1 Negative_regulation of Positive_regulation of IK 1 0.00 1.46 0.41
79 INT241679 EIF2AK3 Positive_regulation of Atf4 1 0.06 0.46 0.4
80 INT113474 MAPK1 Negative_regulation of TNF 1 0.13 0.23 0.4
81 INT194713 MAPK1 Regulation of Gene_expression of TNF 1 0.10 1.66 0.38
82 INT304501 Binding of Ephb1 and Mapk1 1 0.18 0.69 0.36
83 INT304505 Binding of Mapk1 and Uts2d 1 0.01 0.64 0.36
84 INT304532 Binding of Mdk and Mapk1 1 0.02 0.63 0.35
85 INT304495 Trib3 Positive_regulation of Mapk1 1 0.02 1.4 0.35
86 INT304529 Negative_regulation of Binding of Mdk and Mapk1 1 0.02 0.63 0.35
87 INT144966 MAPK1 Positive_regulation of Localization of EGR1 1 0.08 0.83 0.35
88 INT167156 FPR1 Positive_regulation of MAPK1 1 0.18 0.09 0.35
89 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34
90 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33
91 INT167155 FPR1 Positive_regulation of Phosphorylation of MAPK1 1 0.18 0.17 0.33
92 INT303030 Binding of Ednra and MCPH1 1 0.00 1.02 0.32
93 INT346286 ELANE Positive_regulation of MAPK1 1 0.06 0.65 0.32
94 INT346281 Binding of ELANE and MAPK1 1 0.04 0.65 0.32
95 INT194710 MAPK1 Regulation of Gene_expression of IK 1 0.00 0.24 0.31
96 INT309366 Pax2 Negative_regulation of Transcription of Slc6a5 1 0.03 0 0.31
97 INT100029 TNF Positive_regulation of Mapk1 1 0.01 0.78 0.31
98 INT170496 Egf Positive_regulation of Mapk1 3 0.21 0.5 0.3
99 INT112797 Positive_regulation of CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.3
100 INT309369 Ptf1a Positive_regulation of Pax2 1 0.10 0 0.3
101 INT356287 Ngf Positive_regulation of Mapk1 1 0.05 0.17 0.3
102 INT304504 Mapk1 Positive_regulation of Nos1 1 0.29 0.93 0.3
103 INT356278 Gdnf Positive_regulation of Mapk1 1 0.05 0.17 0.3
104 INT112805 CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.29
105 INT295360 Ntn1 Positive_regulation of Ptk2 1 0.09 0.51 0.29
106 INT130107 YY1 Positive_regulation of MAPK1 1 0.45 0 0.28
107 INT132365 Lgals1 Positive_regulation of Mapk1 1 0.03 0.13 0.28
108 INT264472 Mapk1 Regulation of Positive_regulation of Jun 1 0.02 0 0.28
109 INT194821 MAPK1 Regulation of Hand2 1 0.03 1.27 0.28
110 INT130106 Regulation of YY1 Positive_regulation of MAPK1 1 0.41 0 0.28
111 INT130108 DLL3 Negative_regulation of Positive_regulation of MAPK1 1 0.13 0 0.28
112 INT156640 ATF4 Regulation of Gene_expression of S100P 1 0.44 0.88 0.28
113 INT291257 Map3k8 Regulation of Positive_regulation of MAPK1 1 0.09 1 0.28
114 INT141109 Sftpa1 Positive_regulation of Mapk1 1 0.77 0.65 0.27
115 INT194682 Negative_regulation of MAPK1 Positive_regulation of Gene_expression of IL10 1 0.05 0.17 0.27
116 INT270256 MAPK1 Positive_regulation of Mknk1 1 0.03 0.52 0.27
117 INT188209 OSM Positive_regulation of MAPK1 1 0.35 0.47 0.27
118 INT103280 PGR Negative_regulation of Positive_regulation of ATF4 1 0.02 0.31 0.26
119 INT118849 GNA14 Positive_regulation of MAPK1 1 0.00 0.14 0.26
120 INT236005 Positive_regulation of MAPK1 Positive_regulation of Binding of Map2 1 0.04 0 0.25
121 INT236004 Positive_regulation of MAPK1 Positive_regulation of Phosphorylation of Map2 1 0.04 0 0.24
122 INT261650 LGR6 Positive_regulation of MAPK1 1 0.04 0.71 0.24
123 INT130689 CA2 Positive_regulation of ATF4 1 0.13 0.59 0.24
124 INT144967 MAPK1 Positive_regulation of Positive_regulation of EGR1 1 0.08 0.63 0.24
125 INT318678 Atf4 Positive_regulation of Gene_expression of Ddit3 1 0.53 0.77 0.23
126 INT194702 MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.16 0.23
127 INT318679 Atf4 Positive_regulation of Gene_expression of Xbp1 1 0.53 0.77 0.23
128 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
129 INT115143 MAPK1 Positive_regulation of TFAM 2 0.02 0.49 0.22
130 INT188195 GOPC Positive_regulation of MAPK1 2 0.21 0.32 0.22
131 INT283857 APOA5 Positive_regulation of Positive_regulation of MAPK1 1 0.00 0.6 0.22
132 INT112804 IL4I1 Positive_regulation of Positive_regulation of MAPK1 1 0.03 0 0.22
133 INT194725 MAPK1 Regulation of Transcription of IK 1 0.00 0.06 0.22
134 INT136366 MCPH1 Regulation of Localization of Tnf 1 0.01 0.26 0.22
135 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21
136 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
137 INT283860 APOA5 Negative_regulation of MAPK1 1 0.00 0.59 0.21
138 INT291264 Mdk Regulation of Positive_regulation of MAPK1 1 0.02 0.61 0.21
139 INT122871 HTR1A Positive_regulation of MAPK1 1 0.56 0 0.2
140 INT158208 Binding of MAPK1 and TNFSF14 1 0.03 0.3 0.2
141 INT158225 Binding of CCR1 and MAPK1 1 0.18 0.3 0.2
142 INT137228 MAPK1 Positive_regulation of Phosphorylation of Creb1 1 0.46 0 0.2
143 INT158222 Positive_regulation of Binding of MAPK1 and CCR2 1 0.26 0.3 0.2
144 INT158232 Positive_regulation of Binding of MAPK1 and TNFSF14 1 0.04 0.3 0.2
145 INT158204 Negative_regulation of Binding of MAPK1 and CCR2 1 0.22 0.3 0.2
146 INT158227 Negative_regulation of Binding of ICAM1 and MAPK1 1 0.16 0.3 0.2
147 INT158228 Negative_regulation of Binding of MAPK1 and TNFSF14 1 0.04 0.3 0.2
148 INT158236 Positive_regulation of Binding of ICAM1 and MAPK1 1 0.19 0.3 0.2
149 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
150 INT158226 Binding of ICAM1 and MAPK1 1 0.14 0.3 0.2
151 INT158234 Binding of MAPK1 and CCR2 1 0.19 0.3 0.2
152 INT158221 Positive_regulation of Binding of CCR1 and MAPK1 1 0.25 0.3 0.2
153 INT158219 Negative_regulation of Binding of CCR1 and MAPK1 1 0.21 0.3 0.2
154 INT158205 TNFSF14 Positive_regulation of MAPK1 1 0.04 0.3 0.2
155 INT257985 PTGER2 Positive_regulation of MAPK1 1 0.04 0.61 0.2
156 INT194830 MAPK1 Positive_regulation of Gene_expression of Nfatc1 1 0.02 0.08 0.19
157 INT318682 Atf4 Positive_regulation of Ddit3 1 0.73 1.71 0.18
158 INT209930 IL1B Positive_regulation of MAPK1 1 0.13 0.37 0.18
159 INT320260 Binding of Atf4 and Creb1 1 0.15 0.36 0.17
160 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17
161 INT264478 Mapk1 Positive_regulation of Jun 1 0.02 0.12 0.17
162 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
163 INT320256 Binding of Atf4 and Rorb 1 0.06 0.36 0.17
164 INT320263 Binding of Ntrk2 and Atf4 1 0.01 0.38 0.17
165 INT235984 HTR1A Negative_regulation of MAPK1 1 0.01 0 0.16
166 INT303028 Binding of Pah and MCPH1 1 0.02 1.13 0.16
167 INT194700 CD28 Positive_regulation of MAPK1 1 0.10 0.55 0.16
168 INT188199 IL6 Positive_regulation of MAPK1 1 0.27 0.25 0.16
169 INT194708 TNFRSF8 Positive_regulation of MAPK1 1 0.06 0.55 0.16
170 INT304535 Mapk1 Positive_regulation of PRKG1 1 0.05 0.65 0.16
171 INT194667 EPHB6 Positive_regulation of MAPK1 1 0.12 0.54 0.16
172 INT194816 MAPK1 Negative_regulation of Phosphorylation of Nfatc1 1 0.01 0.07 0.15
173 INT194836 MAPK1 Negative_regulation of Nfatc1 1 0.01 0.07 0.15
174 INT141110 Negative_regulation of Sftpa1 Positive_regulation of Mapk1 1 0.47 0.31 0.14
175 INT194697 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL5 1 0.03 0.1 0.14
176 INT147727 Phosphorylation of PTK2 Regulation of Positive_regulation of RAC1 1 0.34 0.32 0.14
177 INT291252 Gene_expression of Map3k8 Positive_regulation of MAPK1 1 0.09 0.64 0.14
178 INT147726 Phosphorylation of PTK2 Regulation of Positive_regulation of PIK3CA 1 0.09 0.32 0.14
179 INT255658 Coq10a Regulation of Negative_regulation of Rgc32 1 0.01 1.14 0.14
180 INT117912 CREB1 Positive_regulation of Positive_regulation of MAPK1 1 0.04 0.89 0.13
181 INT255660 Coq10a Negative_regulation of Rgc32 1 0.02 1.11 0.13
182 INT262289 Regulation of Binding of PPIG and CC2D1A 1 0.01 1.52 0.13
183 INT262290 Binding of PPIG and CC2D1A 1 0.01 1.52 0.13
184 INT91457 IL1B Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.47 0.12
185 INT304500 Binding of Rps6ka1 and Mapk1 1 0.16 0.18 0.12
186 INT356276 Egf Positive_regulation of Positive_regulation of Mapk1 1 0.05 0.52 0.12
187 INT117911 MAPK1 Regulation of Positive_regulation of BIRC2 1 0.04 0.9 0.12
188 INT309371 Lhx1 Positive_regulation of Gene_expression of Pax2 1 0.08 0.07 0.11
189 INT188202 HBE1 Positive_regulation of MAPK1 1 0.01 0.14 0.11
190 INT250632 Binding of MCPH1 and Fbxo23 1 0.01 0 0.11
191 INT309372 Lhx5 Positive_regulation of Gene_expression of Pax2 1 0.09 0.07 0.11
192 INT268943 Binding of Crmp1 and Positive_regulation of Regulation of Ros1 1 0.00 0.2 0.11
193 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11
194 INT304499 Map2k1 Positive_regulation of Mapk1 1 0.12 0.8 0.1
195 INT91454 MAPK1 Positive_regulation of Gene_expression of CPOX 1 0.20 0.6 0.1
196 INT181570 Binding of Edn1 and Mapk1 1 0.13 2.72 0.1
197 INT194822 Negative_regulation of MAPK1 Negative_regulation of Binding of Sp1 1 0.04 0.05 0.1
198 INT194721 MAPK1 Positive_regulation of CREB1 1 0.08 0.05 0.1
199 INT194819 Positive_regulation of Trav6-3 Positive_regulation of MAPK1 1 0.02 0.39 0.1
200 INT194730 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL2 1 0.06 0 0.09

Single Events

The table below shows the top 100 pain related interactions that have been reported for microtubule organizing center. They are ordered first by their pain relevance and then by number of times they were reported in microtubule organizing center. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
2 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
3 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
4 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
5 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
6 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
7 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
8 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
9 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
10 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38
11 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
12 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
13 INT48921 Regulation of Mapk1 25 0.49 19.51 10.41
14 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
15 INT109432 Negative_regulation of Phosphorylation of Mapk1 19 0.54 7.01 8.98
16 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34
17 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59
18 INT139964 Regulation of Phosphorylation of Mapk1 12 0.58 10.04 6.1
19 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9
20 INT206950 Positive_regulation of Atf4 14 0.45 7.02 5.71
21 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
22 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39
23 INT114499 Gene_expression of MCPH1 38 0.67 26.68 4.55
24 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
25 INT133244 Regulation of Positive_regulation of Mapk1 11 0.43 3.52 4.03
26 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
27 INT80347 Positive_regulation of Camk2b 2 0.69 0.33 3.67
28 INT67248 Gene_expression of TACC2 12 0.50 13.51 3.65
29 INT123564 Negative_regulation of Rock2 13 0.59 9.61 3.58
30 INT80345 Gene_expression of Camk2b 3 0.77 0.5 3.44
31 INT241623 Gene_expression of Atf4 12 0.74 8.67 2.85
32 INT200895 Localization of Mapk1 6 0.67 2.08 2.82
33 INT80346 Negative_regulation of Camk2b 3 0.58 0.58 2.81
34 INT169112 Negative_regulation of Positive_regulation of Mapk1 9 0.59 1.84 2.78
35 INT152927 Negative_regulation of Mapk1 16 0.41 5.85 2.73
36 INT103282 Positive_regulation of ATF4 12 0.66 7.28 2.65
37 INT116824 Negative_regulation of Rgc32 21 0.31 21.62 2.46
38 INT137270 Positive_regulation of PDE4D 4 0.48 2.48 2.39
39 INT186116 Regulation of Gene_expression of MAPK1 9 0.44 5.85 2.32
40 INT102908 Phosphorylation of Camk2b 2 0.62 0.42 2.17
41 INT170482 Regulation of Gene_expression of Mapk1 5 0.43 5.73 2.1
42 INT112267 Positive_regulation of Rgc32 10 0.39 8.1 2.09
43 INT109906 Localization of MAPK1 12 0.54 1.68 2.01
44 INT83709 Negative_regulation of Gene_expression of MAPK1 12 0.41 6.57 2.01
45 INT138844 Positive_regulation of CC2D1A 25 0.41 41.36 1.92
46 INT83596 Gene_expression of Ptk2 6 0.76 2.22 1.84
47 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
48 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
49 INT262293 Gene_expression of CC2D1A 21 0.40 44.64 1.5
50 INT130019 Regulation of Phosphorylation of MAPK1 6 0.49 3.6 1.5
51 INT29582 Negative_regulation of BBS9 8 0.57 8.3 1.48
52 INT241618 Regulation of Atf4 3 0.43 1.41 1.46
53 INT130704 Gene_expression of ATF4 9 0.78 5.29 1.45
54 INT153627 Binding of Mapk1 5 0.36 2.88 1.4
55 INT241627 Regulation of Positive_regulation of Atf4 1 0.29 0.36 1.4
56 INT104027 Negative_regulation of Negative_regulation of MAPK1 6 0.56 2.87 1.35
57 INT131115 Regulation of Phosphorylation of Ptk2 2 0.61 0.3 1.34
58 INT241624 Positive_regulation of Positive_regulation of Atf4 1 0.32 0.72 1.32
59 INT303013 Negative_regulation of Gene_expression of MCPH1 1 0.02 5.19 1.32
60 INT250628 Negative_regulation of MCPH1 8 0.17 7.05 1.27
61 INT138843 Binding of CC2D1A 19 0.33 33.06 1.25
62 INT87343 Negative_regulation of Phosphorylation of PTK2 34 0.59 18.38 1.19
63 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
64 INT87346 Binding of PTK2 6 0.37 4.03 1.18
65 INT120664 Positive_regulation of TACC2 3 0.01 7.43 1.08
66 INT80341 Regulation of Gene_expression of Camk2b 1 0.61 0.08 1.08
67 INT87342 Regulation of Phosphorylation of PTK2 3 0.59 5.7 1.05
68 INT116823 Regulation of Rgc32 2 0.44 1.82 1.03
69 INT116801 Negative_regulation of Positive_regulation of Camk2b 1 0.29 0.1 1.02
70 INT83479 Gene_expression of KRT18 30 0.65 27.29 1
71 INT114498 Positive_regulation of MCPH1 10 0.43 5.82 0.91
72 INT26868 Regulation of BBS9 2 0.44 0.71 0.9
73 INT156649 Positive_regulation of Gene_expression of ATF4 3 0.69 2.79 0.88
74 INT241620 Negative_regulation of Positive_regulation of Atf4 1 0.27 0.85 0.88
75 INT87344 Gene_expression of PTK2 90 0.78 59.03 0.87
76 INT219219 Gene_expression of Rgc32 9 0.13 7.29 0.85
77 INT131113 Negative_regulation of Ptk2 3 0.58 0.17 0.85
78 INT318665 Negative_regulation of Gene_expression of Atf4 1 0.56 5.16 0.85
79 INT265568 Binding of PDE4D 1 0.05 0.81 0.85
80 INT226473 Negative_regulation of PDE4D 5 0.19 3.54 0.83
81 INT254143 Negative_regulation of CC2D1A 10 0.35 13.81 0.82
82 INT114501 Transcription of MCPH1 4 0.43 0.71 0.79
83 INT87341 Regulation of Gene_expression of PTK2 2 0.62 8.34 0.77
84 INT194780 Regulation of Negative_regulation of MAPK1 3 0.32 3.42 0.76
85 INT127633 Localization of KRT18 5 0.52 5.93 0.75
86 INT116822 Regulation of Negative_regulation of Rgc32 2 0.20 1.64 0.68
87 INT303012 Positive_regulation of Negative_regulation of MCPH1 1 0.02 2.04 0.64
88 INT102906 Positive_regulation of Gene_expression of Camk2b 1 0.68 0.43 0.63
89 INT102909 Positive_regulation of Phosphorylation of Camk2b 1 0.46 0.43 0.63
90 INT213617 Gene_expression of PDE4D 3 0.53 1.98 0.62
91 INT117437 Protein_catabolism of KRT18 3 0.46 4.64 0.61
92 INT241625 Regulation of Gene_expression of Atf4 2 0.43 0.83 0.59
93 INT167608 Regulation of Rock2 2 0.33 2.47 0.59
94 INT75524 Positive_regulation of Regulation of MAPK1 1 0.43 1.12 0.59
95 INT163221 Protein_catabolism of Krt18 2 0.81 2.18 0.56
96 INT163223 Negative_regulation of Protein_catabolism of Krt18 1 0.35 1.18 0.56
97 INT200956 Negative_regulation of CAMK2B 1 0.37 0.93 0.56
98 INT97956 Negative_regulation of CDC42 3 0.27 1.58 0.55
99 INT147577 Binding of ATF4 1 0.05 0.15 0.54
100 INT147578 Regulation of Binding of ATF4 1 0.07 0.15 0.54
101 INT170475 Negative_regulation of Gene_expression of Mapk1 7 0.41 2.44 0.53
102 INT48163 Localization of TACC2 1 0.06 0.32 0.53
103 INT126628 Positive_regulation of Rock2 4 0.70 3.56 0.52
104 INT29580 Positive_regulation of Gene_expression of BBS9 2 0.49 1.3 0.52
105 INT250743 Localization of CC2D1A 12 0.51 20.97 0.51
106 INT29579 Gene_expression of BBS9 3 0.65 2.69 0.5
107 INT273179 Localization of PDE4D 1 0.34 2.01 0.5
108 INT232826 Gene_expression of Krt18 26 0.68 14.24 0.48
109 INT109911 Positive_regulation of Localization of MAPK1 4 0.33 0.56 0.48
110 INT241626 Negative_regulation of Regulation of Atf4 1 0.28 0.29 0.48
111 INT120665 Binding of TACC2 4 0.07 4.33 0.46
112 INT117772 Binding of Ptk2 1 0.37 0.17 0.46
113 INT177869 Gene_expression of BUB1B 2 0.65 2.11 0.45
114 INT177866 Negative_regulation of BUB1B 1 0.32 1.23 0.45
115 INT177845 Negative_regulation of Gene_expression of BUB1B 1 0.23 0.75 0.45
116 INT159151 Negative_regulation of Negative_regulation of Mapk1 1 0.32 0.38 0.45
117 INT130712 Negative_regulation of Gene_expression of ATF4 1 0.33 0.75 0.43
118 INT137835 Binding of CAMK2B 1 0.08 1.38 0.42
119 INT283239 Negative_regulation of Localization of CC2D1A 1 0.29 10.4 0.41
120 INT140612 Transcription of ATF4 3 0.58 1.73 0.39
121 INT250609 Negative_regulation of Negative_regulation of MCPH1 1 0.12 1.03 0.39
122 INT130709 Negative_regulation of Positive_regulation of ATF4 1 0.44 0.75 0.36
123 INT213507 Gene_expression of Pax2 10 0.67 1.41 0.34
124 INT109907 Protein_catabolism of MAPK1 2 0.58 1.82 0.34
125 INT130113 Regulation of Regulation of MAPK1 1 0.22 0.16 0.33
126 INT126627 Gene_expression of Rock2 9 0.60 3.33 0.32
127 INT156648 Positive_regulation of Transcription of ATF4 1 0.42 0.79 0.32
128 INT232821 Positive_regulation of Gene_expression of Krt18 11 0.50 4.38 0.31
129 INT262297 Negative_regulation of Gene_expression of CC2D1A 2 0.25 2.95 0.31
130 INT262301 Negative_regulation of Positive_regulation of CC2D1A 1 0.06 0.79 0.3
131 INT83594 Negative_regulation of Phosphorylation of Ptk2 5 0.42 1.62 0.29
132 INT309354 Regulation of Pax2 1 0.10 0 0.29
133 INT309339 Negative_regulation of Localization of Pax2 1 0.15 0 0.28
134 INT232828 Regulation of Krt18 1 0.50 2.2 0.26
135 INT164731 Regulation of MCPH1 4 0.45 0.5 0.25
136 INT232845 Positive_regulation of Krt18 1 0.41 4.5 0.24
137 INT289985 Positive_regulation of Positive_regulation of Rgc32 1 0.01 0.93 0.24
138 INT109931 Positive_regulation of Protein_catabolism of MAPK1 1 0.33 0.14 0.24
139 INT119080 Negative_regulation of PTK2 15 0.56 8.88 0.23
140 INT194801 Binding of MAPK1 7 0.29 1.9 0.23
141 INT318676 Negative_regulation of Atf4 3 0.56 1.59 0.23
142 INT183881 Localization of CDC42 3 0.49 1.92 0.23
143 INT232945 Positive_regulation of Gene_expression of KRT18 2 0.49 3.54 0.23
144 INT255656 Transcription of Rgc32 1 0.07 0.76 0.23
145 INT268967 Binding of Crmp1 1 0.05 2.66 0.22
146 INT268958 Localization of Crmp1 1 0.08 2.45 0.22
147 INT200898 Positive_regulation of Localization of Mapk1 1 0.30 0 0.22
148 INT87338 Regulation of PTK2 10 0.62 4.75 0.21
149 INT232831 Binding of Krt18 7 0.39 4.61 0.21
150 INT261680 Positive_regulation of Negative_regulation of MAPK1 2 0.33 1.2 0.21
151 INT159956 Phosphorylation of Rock2 3 0.79 1.57 0.2
152 INT250615 Regulation of Gene_expression of MCPH1 1 0.45 0 0.2
153 INT273181 Negative_regulation of Localization of PDE4D 1 0.18 0.68 0.2
154 INT183876 Regulation of CDC42 3 0.30 1.94 0.19
155 INT262295 Regulation of CC2D1A 3 0.27 5.38 0.19
156 INT275543 Negative_regulation of Gene_expression of PDE4D 1 0.11 0.87 0.19
157 INT232962 Binding of KRT18 4 0.26 2.38 0.18
158 INT292483 Negative_regulation of Positive_regulation of PTK2 2 0.41 3.51 0.18
159 INT325301 Negative_regulation of C14orf166 1 0.44 1.32 0.18
160 INT263407 Binding of Rock2 1 0.02 0 0.18
161 INT356268 Regulation of Localization of Mapk1 1 0.04 0.35 0.17
162 INT121338 Binding of MTUS1 5 0.07 3.41 0.16
163 INT325306 Localization of C14orf166 1 0.57 2.44 0.16
164 INT190389 Transcription of MAPK1 2 0.44 2.58 0.15
165 INT147730 Regulation of Positive_regulation of PTK2 1 0.35 0.33 0.15
166 INT200987 Transcription of CAMK2B 2 0.44 0.2 0.14
167 INT309352 Localization of Pax2 1 0.27 0 0.14
168 INT83595 Negative_regulation of Gene_expression of Ptk2 1 0.23 1.62 0.14
169 INT131114 Positive_regulation of Gene_expression of Ptk2 1 0.49 0.27 0.14
170 INT200978 Regulation of Transcription of CAMK2B 1 0.29 0.15 0.14
171 INT172370 Binding of MCPH1 6 0.34 4.75 0.13
172 INT59955 Gene_expression of RASSF1 3 0.60 3.43 0.13
173 INT206133 Binding of CDC42 3 0.25 0.8 0.12
174 INT250624 Localization of MCPH1 1 0.23 0 0.12
175 INT318674 Transcription of Atf4 3 0.69 1.26 0.1
176 INT201994 Regulation of TACC2 2 0.03 0.21 0.1
177 INT262294 Positive_regulation of Gene_expression of CC2D1A 2 0.30 2.74 0.09
178 INT152987 Gene_expression of TUBE1 2 0.65 0.9 0.09
179 INT101213 Gene_expression of MTUS1 2 0.02 2.72 0.09
180 INT126625 Transcription of Rock2 1 0.67 0 0.09
181 INT306176 Localization of Rock2 1 0.73 0.41 0.09
182 INT101212 Positive_regulation of Gene_expression of MTUS1 1 0.01 2.31 0.09
183 INT126624 Negative_regulation of Transcription of Rock2 1 0.41 0 0.09
184 INT152986 Positive_regulation of Gene_expression of TUBE1 1 0.49 0.91 0.09
185 INT232839 Phosphorylation of Krt18 1 0.67 1.78 0.09
186 INT232848 Negative_regulation of Gene_expression of Krt18 5 0.36 2.3 0.08
187 INT234676 Gene_expression of SNCG 4 0.78 63.59 0.08
188 INT29581 Positive_regulation of BBS9 1 0.49 1.3 0.08
189 INT29578 Negative_regulation of Positive_regulation of BBS9 1 0.41 1.36 0.08
190 INT147735 Regulation of Binding of PTK2 1 0.35 0.23 0.08
191 INT164061 Negative_regulation of ATF4 1 0.59 0.82 0.08
192 INT221377 Localization of Krt18 4 0.61 1.82 0.07
193 INT59954 Localization of RASSF1 3 0.73 3.12 0.07
194 INT59953 Positive_regulation of Localization of RASSF1 1 0.00 0.75 0.07
195 INT283234 Positive_regulation of Protein_catabolism of CC2D1A 1 0.30 1.77 0.07
196 INT268965 Negative_regulation of Crmp1 1 0.04 1.28 0.07
197 INT219608 Regulation of RASSF1 1 0.01 0 0.07
198 INT144400 Positive_regulation of Gene_expression of PTK2 33 0.70 21.24 0.06
199 INT255654 Binding of Rgc32 1 0.04 1.34 0.06
200 INT325300 Gene_expression of C14orf166 1 0.51 1.92 0.06
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