GO:0005819

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Name spindle
Categary Component
Go Slim No
Go Link GO:0005819
Unique Molecular Interactions 742
Total Molecular Interactions 1037
Total Single Events 6919
Pain Genes Associated 46

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for spindle. They are ordered first by their pain relevance and then by number of times they were reported for spindle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
3 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
4 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
5 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
6 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
7 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
8 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
9 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
10 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
11 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
12 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
13 INT146352 Binding of Rgs14 and Mors1 1 0.23 0.27 1.17
14 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
15 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
16 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
17 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
18 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
19 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
20 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
21 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
22 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
23 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
24 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
25 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
26 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
27 INT116269 Binding of Myc and Mycbp2 1 0.19 0.5 0.87
28 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
29 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
30 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
31 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
32 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
33 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
34 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
35 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
36 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
37 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
38 INT278077 Binding of BPHL and AURKC 1 0.16 4.29 0.69
39 INT314560 RYBP Positive_regulation of Gene_expression of MYC 1 0.02 0.06 0.67
40 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
41 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
42 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
43 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
44 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
45 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
46 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
47 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
48 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
49 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
50 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
51 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
52 INT54942 Rb1 Regulation of Gab1 1 0.02 0.39 0.59
53 INT120348 Negative_regulation of Binding of DES and MYC 1 0.06 0.18 0.58
54 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
55 INT120350 Binding of DES and MYC 1 0.05 0.17 0.58
56 INT120347 Binding of KNG1 and MYC 1 0.21 0.17 0.58
57 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
58 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
59 INT28119 Atm Negative_regulation of Cck 1 0.42 0 0.56
60 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55
61 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
62 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
63 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
64 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
65 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
66 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
67 INT160779 Cps1 Positive_regulation of ATM 1 0.01 0.94 0.53
68 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
69 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
70 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
71 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49
72 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
73 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
74 INT231340 INCENP Regulation of Gene_expression of IL6 1 0.01 1.09 0.47
75 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
76 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
77 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
78 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
79 INT349853 Binding of Hspb1 and Jun 1 0.14 2.3 0.45
80 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44
81 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
82 INT322396 Hist1h1t Positive_regulation of Akt1 1 0.01 0 0.42
83 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
84 INT290269 KNG1 Positive_regulation of Binding of MID1 1 0.02 1.06 0.41
85 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
86 INT290270 KNG1 Positive_regulation of MID1 1 0.02 1.06 0.41
87 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
88 INT231842 Pcdh8 Positive_regulation of Akt1 1 0.00 1.59 0.4
89 INT338044 F2 Positive_regulation of Pard3 1 0.08 0.38 0.4
90 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4
91 INT166155 Ccr9 Positive_regulation of Akt1 1 0.58 2.14 0.39
92 INT256321 INCENP Positive_regulation of Gene_expression of Vcam1 1 0.00 1.89 0.38
93 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37
94 INT296304 Binding of SPIN1 and ENDO1 1 0.03 1.7 0.37
95 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37
96 INT296306 Binding of BGLAP and SPIN1 1 0.05 1.69 0.37
97 INT85782 Rb1 Regulation of PRKG1 1 0.00 0.38 0.37
98 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36
99 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36
100 INT230438 Binding of PDX1 and HAUS7 1 0.02 2.29 0.35
101 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
102 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
103 INT346145 Binding of ADM and TPX2 1 0.01 1.05 0.35
104 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
105 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
106 INT309118 Dlat Positive_regulation of Positive_regulation of Akt1 1 0.03 0.32 0.34
107 INT249019 Gabrg1 Positive_regulation of Akt1 1 0.02 0 0.34
108 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
109 INT204080 HP Negative_regulation of Phosphorylation of Rb1 1 0.00 3.53 0.34
110 INT239540 Binding of CXCR2 and MYC 1 0.15 0.09 0.33
111 INT28006 NPC1 Negative_regulation of Positive_regulation of Rps6ka1 1 0.01 0.37 0.33
112 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33
113 INT28005 NPC1 Negative_regulation of Rps6ka1 1 0.01 0.45 0.32
114 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
115 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
116 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
117 INT303063 Akt1 Negative_regulation of Gene_expression of Syn1 1 0.09 0.45 0.31
118 INT54943 Gab1 Regulation of Rb1 1 0.02 0.2 0.31
119 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
120 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
121 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 0.37 3.89 0.29
122 INT239537 CXCR2 Regulation of MYC 1 0.15 0.05 0.29
123 INT226375 INCENP Positive_regulation of Regulation of TH1L 1 0.01 0.57 0.29
124 INT226376 INCENP Negative_regulation of Gene_expression of TH1L 1 0.00 0.61 0.29
125 INT132367 Lgals1 Positive_regulation of Akt1 1 0.22 0.13 0.28
126 INT317533 Akt1 Positive_regulation of Nos1 1 0.43 0 0.28
127 INT226383 IL22 Positive_regulation of Gene_expression of INCENP 1 0.00 0.85 0.28
128 INT149322 Amph Positive_regulation of Akt1 1 0.39 0 0.27
129 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
130 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26
131 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26
132 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26
133 INT303082 Akt1 Negative_regulation of Gene_expression of Mafk 1 0.20 0.37 0.26
134 INT308661 Akt1 Positive_regulation of Chuk 1 0.02 0.6 0.25
135 INT327300 Binding of Hnrnpd and Myc 1 0.12 1.02 0.25
136 INT314047 THL Negative_regulation of Phosphorylation of Akt1 1 0.14 0.71 0.25
137 INT326094 Akt1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.49 0.24
138 INT326092 Gene_expression of Akt1 Negative_regulation of Gopc 1 0.03 0.55 0.24
139 INT326093 Akt1 Positive_regulation of Gopc 1 0.03 0.43 0.23
140 INT252213 INCENP Regulation of Lgals3 1 0.00 1.91 0.23
141 INT183945 INCENP Positive_regulation of Localization of IL6 1 0.00 0.2 0.23
142 INT346143 ADM Regulation of Gene_expression of TPX2 1 0.02 1.29 0.23
143 INT323173 THRA Positive_regulation of Phosphorylation of Akt1 1 0.00 0 0.22
144 INT260844 NRP2 Positive_regulation of Akt1 1 0.00 0.73 0.22
145 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
146 INT323174 DBT Positive_regulation of Phosphorylation of Akt1 1 0.01 0 0.21
147 INT269994 Binding of Nfkb2 and Tpx2 1 0.04 0.51 0.21
148 INT116468 VEGFA Positive_regulation of Akt1 1 0.04 1.39 0.21
149 INT289356 Binding of Akt1 and Fgf2 1 0.03 0.82 0.21
150 INT309661 C5 Positive_regulation of Phosphorylation of Akt1 1 0.51 0.45 0.21
151 INT52355 Cfp Negative_regulation of Ndel1 1 0.34 0.16 0.21
152 INT269995 Positive_regulation of Binding of Nfkb2 and Tpx2 1 0.05 0.51 0.21
153 INT221237 Prkca Regulation of Phosphorylation of Akt1 1 0.01 0.28 0.2
154 INT226384 INCENP Positive_regulation of IL19 1 0.00 0.58 0.2
155 INT68510 Binding of ATM and PRLR 1 0.01 0 0.19
156 INT265048 INCENP Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.69 0.19
157 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
158 INT349855 Atf3 Regulation of Hspb1 1 0.37 0.77 0.19
159 INT186098 EGF Positive_regulation of MAP2K5 1 0.01 0.19 0.18
160 INT334631 Igf1r Positive_regulation of Phosphorylation of Akt1 1 0.19 0.5 0.18
161 INT226372 INCENP Negative_regulation of Gene_expression of IL5 1 0.00 1.12 0.18
162 INT179158 ATM Regulation of Gene_expression of GOPC 1 0.01 0 0.18
163 INT303058 Akt1 Negative_regulation of Gene_expression of Syt1 1 0.21 0.43 0.18
164 INT221231 Pdpk1 Positive_regulation of Akt1 1 0.09 0.13 0.18
165 INT231866 INCENP Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
166 INT179163 ATM Regulation of Gene_expression of IL13 1 0.01 0 0.18
167 INT262359 Binding of DISC1 and NDEL1 1 0.04 0.56 0.18
168 INT221244 Pdpk1 Positive_regulation of Phosphorylation of Akt1 1 0.09 0.13 0.18
169 INT179161 ATM Regulation of Gene_expression of IL6 1 0.02 0 0.18
170 INT179162 ATM Regulation of Gene_expression of IL8 1 0.01 0 0.18
171 INT253129 Ins1 Regulation of Phosphorylation of Akt1 3 0.11 1.66 0.17
172 INT179841 Il11 Regulation of Positive_regulation of Akt1 1 0.08 0.07 0.17
173 INT302553 Binding of CD8A and MID1 1 0.01 0.38 0.17
174 INT282858 Bpifa2 Negative_regulation of Akt1 1 0.05 0.91 0.17
175 INT226209 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.10 1.16 0.17
176 INT282861 Bpifa2 Negative_regulation of Phosphorylation of Akt1 1 0.05 0.91 0.17
177 INT222443 INCENP Positive_regulation of Localization of Pomc 1 0.00 0.75 0.17
178 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
179 INT218937 Akt1 Positive_regulation of Parn 1 0.01 0.65 0.16
180 INT316484 Akt1 Positive_regulation of Positive_regulation of Stat3 1 0.01 0.87 0.16
181 INT343475 Epo Regulation of Akt1 1 0.18 0.41 0.16
182 INT343478 Epo Regulation of Gene_expression of Akt1 1 0.40 0.41 0.16
183 INT221899 Rb1 Positive_regulation of Transcription of Ccl20 1 0.01 0.62 0.16
184 INT221908 Rb1 Positive_regulation of Transcription of TNIP2 1 0.01 0.62 0.16
185 INT218930 Akt1 Positive_regulation of Xiap 1 0.06 0.64 0.16
186 INT116268 Binding of Myc and Acsl1 1 0.08 0.19 0.16
187 INT226367 INCENP Negative_regulation of SOCS1 1 0.01 0.47 0.15
188 INT224697 TNF Positive_regulation of Akt1 1 0.01 0 0.15
189 INT293698 Positive_regulation of Binding of Akt1 and Plek 1 0.05 0.12 0.15
190 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
191 INT255258 Binding of Rb1 and Tsp1 1 0.38 0.95 0.15
192 INT293695 Binding of Akt1 and Plek 1 0.03 0.12 0.15
193 INT292749 Akt1 Positive_regulation of Ctnnd2 1 0.09 1.73 0.15
194 INT231844 Pcdh8 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.63 0.15
195 INT224694 Il1 Positive_regulation of Akt1 1 0.01 0 0.15
196 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15
197 INT293699 Regulation of Binding of Akt1 and Plek 1 0.04 0.12 0.15
198 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15
199 INT213005 Hdl1 Positive_regulation of Akt1 3 0.19 3.81 0.14
200 INT253122 Ins1 Positive_regulation of Akt1 2 0.15 1.81 0.14

Single Events

The table below shows the top 100 pain related interactions that have been reported for spindle. They are ordered first by their pain relevance and then by number of times they were reported in spindle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
2 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
3 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
4 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
5 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
6 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
7 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
8 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
9 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
10 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31
11 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36
12 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
13 INT174838 Localization of INCENP 80 0.64 19.05 12.89
14 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
15 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
16 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
17 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
18 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
19 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
20 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
21 INT173639 Positive_regulation of INCENP 40 0.14 20.97 6.7
22 INT8101 Binding of INCENP 42 0.31 16.2 6.68
23 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
24 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
25 INT178604 Gene_expression of TPX2 13 0.37 20.29 6.04
26 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82
27 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
28 INT80038 Positive_regulation of Gene_expression of MYC 24 0.67 13.93 5.17
29 INT165058 Negative_regulation of MID1 14 0.37 10.82 4.67
30 INT134657 Localization of Akt1 37 0.68 11.58 4.62
31 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
32 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39
33 INT75136 Binding of Akt1 27 0.27 8.81 4.15
34 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
35 INT146350 Phosphorylation of Rgs14 1 0.80 0.79 3.77
36 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
37 INT136692 Localization of Akt1 12 0.78 2.14 3.65
38 INT20419 Negative_regulation of Gene_expression of MYC 19 0.57 9.7 3.29
39 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
40 INT192450 Gene_expression of CLTC 26 0.55 18.82 3.26
41 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
42 INT172551 Negative_regulation of INCENP 38 0.07 20.83 3.14
43 INT165057 Binding of MID1 7 0.32 4.13 3.12
44 INT29929 Gene_expression of Rb1 20 0.69 5.81 3.1
45 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
46 INT73263 Negative_regulation of MYC 20 0.57 12.86 2.95
47 INT172177 Protein_catabolism of INCENP 18 0.37 6.34 2.91
48 INT36886 Transcription of Myc 6 0.69 3.16 2.86
49 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
50 INT24068 Localization of Hspb1 6 0.78 6.11 2.75
51 INT178606 Positive_regulation of Gene_expression of TPX2 4 0.08 8.73 2.71
52 INT54938 Regulation of Rb1 6 0.44 4.41 2.69
53 INT73460 Positive_regulation of Gene_expression of Myc 26 0.67 20.44 2.61
54 INT214355 Binding of Akt1 13 0.36 3.72 2.59
55 INT222400 Negative_regulation of Localization of INCENP 4 0.02 1.82 2.46
56 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36
57 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31
58 INT82798 Regulation of MYC 19 0.60 12.06 2.31
59 INT165059 Gene_expression of MID1 11 0.58 3.68 2.31
60 INT107685 Phosphorylation of MYC 3 0.80 2.52 2.28
61 INT86426 Gene_expression of Hspb1 16 0.78 10.86 2.26
62 INT138286 Regulation of Positive_regulation of Akt1 13 0.45 4.93 2.22
63 INT173090 Regulation of INCENP 24 0.09 9.45 2.16
64 INT73476 Transcription of MYC 18 0.69 12.14 2.13
65 INT46849 Regulation of TPX2 5 0.24 6.27 2.1
66 INT20421 Positive_regulation of MYC 19 0.67 10.43 1.9
67 INT236867 Gene_expression of AURKC 6 0.55 31.96 1.86
68 INT118511 Gene_expression of Pard3 5 0.57 0.76 1.86
69 INT155110 Negative_regulation of Phosphorylation of MYC 1 0.57 1.61 1.83
70 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78
71 INT181280 Regulation of Gene_expression of INCENP 5 0.07 4 1.78
72 INT142236 Regulation of Phosphorylation of Akt1 13 0.61 5.02 1.75
73 INT165332 Negative_regulation of Negative_regulation of Akt1 5 0.42 3.27 1.7
74 INT257820 Positive_regulation of PAFAH1B1 1 0.68 11.09 1.69
75 INT73475 Positive_regulation of Transcription of MYC 7 0.67 5.46 1.66
76 INT57971 Regulation of Rb1 5 0.41 2.36 1.66
77 INT126276 Regulation of Rgs14 1 0.39 0.71 1.63
78 INT234116 Positive_regulation of MID1 9 0.03 3.78 1.61
79 INT117714 Regulation of Positive_regulation of Akt1 3 0.61 0.44 1.61
80 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57
81 INT46851 Negative_regulation of TPX2 3 0.38 1.68 1.54
82 INT28003 Positive_regulation of Rps6ka1 4 0.16 2.25 1.46
83 INT236868 Negative_regulation of AURKC 3 0.48 12.2 1.46
84 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36
85 INT116265 Binding of Myc 9 0.36 4.28 1.36
86 INT46848 Positive_regulation of TPX2 9 0.70 5.01 1.35
87 INT171975 Negative_regulation of Gene_expression of INCENP 8 0.05 5.24 1.35
88 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32
89 INT24069 Negative_regulation of Localization of Hspb1 3 0.14 3.93 1.3
90 INT20418 Regulation of Gene_expression of MYC 6 0.60 4.4 1.29
91 INT173877 Positive_regulation of Gene_expression of INCENP 14 0.08 7.83 1.28
92 INT63905 Regulation of RB1 13 0.62 12.67 1.28
93 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26
94 INT152255 Gene_expression of ATM 14 0.71 12.53 1.26
95 INT146351 Positive_regulation of Phosphorylation of Rgs14 1 0.45 0.27 1.23
96 INT41124 Negative_regulation of Rb1 11 0.44 3.17 1.22
97 INT296307 Positive_regulation of SPIN1 1 0.11 7.1 1.15
98 INT142950 Protein_catabolism of ERCC2 2 0.25 1.45 1.14
99 INT71848 Positive_regulation of Transcription of Myc 1 0.67 0.16 1.11
100 INT207203 Transcription of Akt1 6 0.67 3.73 1.1
101 INT165056 Regulation of Gene_expression of MID1 2 0.39 0.93 1.1
102 INT247970 Regulation of CLTC 8 0.28 5.37 1.06
103 INT123962 Phosphorylation of Hspb1 8 0.82 2.08 1.04
104 INT191050 Positive_regulation of Negative_regulation of Akt1 6 0.31 1.82 1.03
105 INT230440 Gene_expression of HAUS7 1 0.04 4.13 1.02
106 INT257824 Localization of PAFAH1B1 1 0.74 6.58 1
107 INT125892 Regulation of Hspb1 2 0.48 4.28 0.98
108 INT126279 Gene_expression of Rgs14 1 0.67 0.34 0.98
109 INT102070 Regulation of Gene_expression of Myc 4 0.60 2.68 0.96
110 INT24067 Negative_regulation of Hspb1 1 0.11 0.67 0.95
111 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94
112 INT174188 Positive_regulation of Gene_expression of RB1 9 0.45 6.22 0.94
113 INT17894 Regulation of Myc 10 0.60 5.65 0.93
114 INT163508 Regulation of Gene_expression of Akt1 3 0.45 1.65 0.92
115 INT60553 Localization of TPX2 2 0.61 3.02 0.92
116 INT312277 Binding of TPX2 3 0.08 0.76 0.91
117 INT82795 Binding of MYC 16 0.47 6.1 0.9
118 INT296308 Localization of SPIN1 1 0.12 4.69 0.89
119 INT236871 Binding of AURKC 2 0.39 8.53 0.83
120 INT95190 Gene_expression of NDEL1 1 0.29 0 0.81
121 INT169911 Phosphorylation of Rb1 35 0.73 18.58 0.79
122 INT180752 Gene_expression of PAFAH1B1 3 0.66 9.89 0.75
123 INT41123 Positive_regulation of Rb1 12 0.44 3.03 0.73
124 INT151170 Regulation of Regulation of Akt1 2 0.45 3.28 0.73
125 INT109983 Positive_regulation of Hspb1 7 0.66 6.66 0.72
126 INT296309 Binding of SPIN1 1 0.06 3.54 0.72
127 INT257817 Regulation of PAFAH1B1 1 0.60 4.93 0.7
128 INT125890 Negative_regulation of Regulation of Hspb1 2 0.42 1.39 0.69
129 INT268557 Regulation of Regulation of MYC 1 0.44 0.86 0.69
130 INT28118 Binding of Atm 13 0.38 12.24 0.68
131 INT181282 Transcription of INCENP 10 0.11 1.21 0.66
132 INT207204 Regulation of Transcription of Akt1 3 0.35 1.41 0.66
133 INT169931 Localization of Rb1 6 0.70 4.79 0.65
134 INT70216 Gene_expression of HSPB1 8 0.78 4.81 0.64
135 INT246642 Binding of CLTCL1 3 0.17 1.32 0.63
136 INT281466 Negative_regulation of Regulation of Akt1 1 0.33 0.31 0.63
137 INT35943 Positive_regulation of NDEL1 1 0.31 0 0.62
138 INT311777 Regulation of MID1 3 0.16 4.43 0.6
139 INT107686 Positive_regulation of Negative_regulation of MYC 2 0.49 1.59 0.6
140 INT285478 Negative_regulation of Rgs14 1 0.27 1.25 0.6
141 INT48212 Binding of ATM 5 0.47 3.89 0.57
142 INT160778 Transcription of ATM 1 0.40 1.03 0.57
143 INT62266 Phosphorylation of Rb1 4 0.71 2.68 0.54
144 INT236865 Positive_regulation of AURKC 3 0.57 18.45 0.54
145 INT218900 Regulation of Negative_regulation of Akt1 3 0.15 1.73 0.53
146 INT160776 Positive_regulation of Positive_regulation of ATM 2 0.43 0.94 0.53
147 INT304786 Gene_expression of Rps6ka1 1 0.07 0.69 0.52
148 INT304788 Positive_regulation of Gene_expression of Rps6ka1 1 0.05 0.7 0.52
149 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51
150 INT123963 Positive_regulation of Gene_expression of Hspb1 7 0.70 3.39 0.51
151 INT134070 Binding of ERCC2 3 0.27 0.76 0.51
152 INT276189 Regulation of Localization of Akt1 1 0.43 0.2 0.5
153 INT257816 Negative_regulation of PAFAH1B1 1 0.58 3.66 0.49
154 INT93397 Negative_regulation of Phosphorylation of Rb1 1 0.51 0.32 0.48
155 INT35942 Negative_regulation of NDEL1 1 0.27 0 0.47
156 INT302554 Localization of MID1 3 0.19 0.67 0.44
157 INT228298 Gene_expression of INVS 10 0.65 6.44 0.43
158 INT102181 Negative_regulation of CLTC 5 0.37 1.37 0.42
159 INT123960 Negative_regulation of Phosphorylation of Hspb1 2 0.43 0.48 0.42
160 INT297020 Positive_regulation of CLTC 5 0.36 3.38 0.41
161 INT194993 Binding of RB1 15 0.37 10.96 0.4
162 INT196916 Negative_regulation of Rb1 13 0.42 14.29 0.4
163 INT90354 Negative_regulation of Myc 6 0.57 4.24 0.4
164 INT103901 Regulation of ERCC2 1 0.23 0.51 0.4
165 INT353342 Positive_regulation of Positive_regulation of INCENP 1 0.01 0.46 0.4
166 INT315892 Negative_regulation of Binding of ATM 1 0.07 1.41 0.4
167 INT168961 Positive_regulation of Gene_expression of CLTCL1 1 0.14 0 0.4
168 INT168956 Gene_expression of CLTCL1 1 0.19 0 0.4
169 INT154768 Negative_regulation of ATM 10 0.57 7.05 0.39
170 INT41125 Positive_regulation of Localization of Rb1 2 0.38 0.78 0.39
171 INT41126 Localization of Rb1 2 0.61 0.78 0.39
172 INT95191 Protein_catabolism of NDEL1 1 0.22 0 0.39
173 INT123964 Transcription of Hspb1 2 0.53 0.67 0.37
174 INT344613 Negative_regulation of Gene_expression of CLTC 2 0.31 1.19 0.37
175 INT144275 Negative_regulation of Atm 9 0.59 8.48 0.36
176 INT236870 Positive_regulation of Gene_expression of AURKC 3 0.41 10.18 0.35
177 INT192448 Positive_regulation of Gene_expression of CLTC 5 0.32 3.01 0.33
178 INT196925 Positive_regulation of Gene_expression of Rb1 4 0.45 3.16 0.33
179 INT28004 Negative_regulation of Rps6ka1 1 0.03 0.36 0.33
180 INT169918 Negative_regulation of Phosphorylation of Rb1 8 0.37 6.64 0.32
181 INT222401 Regulation of Localization of INCENP 2 0.01 0.81 0.32
182 INT349820 Regulation of Regulation of Hspb1 1 0.35 2.99 0.32
183 INT321348 Positive_regulation of Localization of Akt1 1 0.30 0.08 0.32
184 INT197599 Transcription of Rb1 4 0.63 0.87 0.3
185 INT105142 Positive_regulation of HSPB1 3 0.70 1.08 0.3
186 INT230442 Binding of HAUS7 1 0.02 2.2 0.3
187 INT192447 Localization of CLTC 6 0.44 2.32 0.29
188 INT86428 Binding of Hspb1 1 0.36 0.53 0.29
189 INT258689 Regulation of Gene_expression of Hspb1 1 0.36 0.34 0.29
190 INT184629 Negative_regulation of Positive_regulation of INCENP 1 0.05 0.89 0.28
191 INT167438 Localization of ATM 3 0.55 1.61 0.27
192 INT111124 Positive_regulation of INVS 3 0.49 0.73 0.27
193 INT208930 Positive_regulation of Pard3 2 0.33 0.49 0.27
194 INT226431 Phosphorylation of INCENP 3 0.04 3.41 0.26
195 INT187547 Localization of Myc 1 0.68 0.92 0.26
196 INT187548 Regulation of Transcription of Myc 1 0.44 0.68 0.26
197 INT172445 Positive_regulation of Gene_expression of Myc 58 0.70 39.62 0.25
198 INT197121 Positive_regulation of Atm 24 0.69 6.81 0.25
199 INT239464 Regulation of Negative_regulation of Akt1 3 0.31 0.37 0.25
200 INT35719 Gene_expression of Atm 34 0.78 15.75 0.24
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