GO:0005845

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Name mRNA cap binding complex
Categary Component
Go Slim No
Go Link GO:0005845
Unique Molecular Interactions 73
Total Molecular Interactions 134
Total Single Events 377
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mRNA cap binding complex. They are ordered first by their pain relevance and then by number of times they were reported for mRNA cap binding complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT341218 Binding of Eif4e and Eif4ebp1 1 0.19 2.65 1.23
2 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54
3 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5
4 INT151545 Adcy1 Positive_regulation of Regulation of Fmr1 1 0.48 0.37 0.37
5 INT151544 Camk4 Positive_regulation of Regulation of Fmr1 1 0.50 0.36 0.37
6 INT341215 Binding of Eif4e and Eif4g3 1 0.10 0.41 0.33
7 INT204478 Fmr1 Regulation of Gene_expression of App 1 0.50 1.44 0.16
8 INT273901 Mtor Positive_regulation of Eif4e 1 0.50 0.54 0.14
9 INT204497 Fmr1 Regulation of Positive_regulation of Gria1 1 0.04 1.75 0.14
10 INT204489 Fmr1 Regulation of App 1 0.50 1.71 0.13
11 INT341239 Binding of EIF4E and Eif4e 1 0.08 0.23 0.12
12 INT341238 Binding of EIF4E and Eif4g3 1 0.03 0.23 0.12
13 INT337072 Binding of Fmr1 and Gusb 1 0.19 1.55 0.08
14 INT204487 Positive_regulation of Fmr1 Regulation of Gene_expression of App 1 0.30 0.8 0.08
15 INT107722 ASIP Negative_regulation of EIF4E1B 1 0.02 0.43 0.07
16 INT341220 Eif4e Positive_regulation of Eif4ebp1 1 0.20 0.42 0.06
17 INT257879 Negative_regulation of Eif4e Positive_regulation of Cdkn1b 1 0.28 0.54 0.06
18 INT257867 Negative_regulation of Eif4e Positive_regulation of Rb1 1 0.05 0.54 0.06
19 INT287613 Binding of Fmr1 and Cysltr1 1 0.01 0.18 0.04
20 INT341225 Negative_regulation of Binding of Eif4e and Eif4ebp1 1 0.17 0.14 0.03
21 INT222259 EIF4E Regulation of Negative_regulation of NOD2 1 0.13 0.1 0
22 INT287620 Fmr1 Regulation of Gene_expression of Fxr2 1 0.43 0 0
23 INT287609 Fmr1 Regulation of Protein_catabolism of Dlg4 1 0.05 0.06 0
24 INT204479 Fmr1 Negative_regulation of Mtap1b 1 0.23 0.68 0
25 INT341232 Binding of EIF4A2 and Eif4e 1 0.06 0 0
26 INT204485 Binding of Cish and Fmr1 1 0.01 0 0
27 INT204503 Binding of Fmr1 and RNPC3 1 0.01 0 0
28 INT204495 Fmr1 Negative_regulation of Transcription of Mtap1b 1 0.22 0.68 0
29 INT204499 App Regulation of Fmr1 1 0.50 0.59 0
30 INT204492 Negative_regulation of Binding of App and Fmr1 1 0.42 0.28 0
31 INT204480 Fmr1 Negative_regulation of Positive_regulation of Scn10a 1 0.17 0.74 0
32 INT287612 Binding of Fmr1 and Dnajc13 1 0.01 0.84 0
33 INT341240 Binding of EIF4E and Eif4ebp1 1 0.04 0.5 0
34 INT341221 Eif4e Regulation of Binding of Eif4ebp1 1 0.18 0 0
35 INT287605 Binding of Fmr1 and Kdm5d 1 0.01 0 0
36 INT204474 Fmr1 Negative_regulation of Transcription of Map1b 1 0.41 0.68 0
37 INT287610 Binding of Fmr1 and Fxr1 1 0.46 0 0
38 INT287616 Ap3b1 Regulation of Binding of Fmr1 1 0.01 0 0
39 INT287611 Fmr1 Regulation of Gene_expression of Fxr1 1 0.38 0 0
40 INT217777 EIF4E Regulation of Gene_expression of MAP3K3 1 0.05 0.19 0
41 INT204490 Binding of Fmr1 and Scn10a 1 0.15 0 0
42 INT204482 Fmr1 Negative_regulation of App 1 0.42 0.74 0
43 INT341234 Eif4g3 Positive_regulation of Binding of EIF4E 1 0.04 0 0
44 INT341216 Regulation of Binding of Eif4e and Eif4ebp1 1 0.11 0 0
45 INT204488 Binding of Fmr1 and Ncl 1 0.12 0.61 0
46 INT217790 EIF4E Regulation of Gene_expression of RASGRP1 1 0.01 0.19 0
47 INT204486 Fmr1 Negative_regulation of Scn10a 1 0.17 0.74 0
48 INT293811 Negative_regulation of EIF4E Negative_regulation of Gene_expression of CCND3 1 0.02 0.32 0
49 INT204484 Binding of Fmr1 and Iqcg 1 0.01 0.21 0
50 INT341230 Eif4g3 Positive_regulation of EIF4E 1 0.04 0 0
51 INT341233 Positive_regulation of Binding of EIF4E and Eif4ebp1 1 0.06 0.5 0
52 INT341224 Eif4g3 Positive_regulation of Eif4e 1 0.14 0 0
53 INT287619 Fmr1 Regulation of Dlg4 1 0.12 0.06 0
54 INT204475 Fmr1 Negative_regulation of Map1b 1 0.41 0.68 0
55 INT204498 Binding of Fmr1 and 7G1 1 0.39 0.15 0
56 INT287608 Binding of Fmr1 and Fxr2 1 0.52 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mRNA cap binding complex. They are ordered first by their pain relevance and then by number of times they were reported in mRNA cap binding complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT151538 Positive_regulation of Fmr1 21 0.68 12.24 2.07
2 INT151543 Binding of Fmr1 56 0.48 19.4 1.65
3 INT136788 Regulation of Eif4e 3 0.61 0 1.61
4 INT151540 Regulation of Fmr1 8 0.59 6.08 1.34
5 INT151542 Positive_regulation of Positive_regulation of Fmr1 4 0.58 2.17 1.2
6 INT136783 Regulation of Regulation of Eif4e 1 0.45 0 1.16
7 INT136785 Phosphorylation of Eif4e 2 0.82 0 1.1
8 INT341195 Binding of Eif4e 1 0.38 3.87 0.92
9 INT151539 Negative_regulation of Fmr1 9 0.59 11.85 0.87
10 INT204463 Gene_expression of Fmr1 50 0.78 23.73 0.78
11 INT246552 Transcription of Fmr1 11 0.72 6.72 0.71
12 INT136780 Positive_regulation of Eif4e 1 0.50 0 0.55
13 INT151536 Regulation of Regulation of Fmr1 1 0.43 0.53 0.33
14 INT341182 Regulation of Eif4e 1 0.35 0.75 0.25
15 INT204468 Negative_regulation of Gene_expression of Fmr1 5 0.59 7.5 0.19
16 INT341163 Positive_regulation of Eif4e 1 0.54 0.56 0.19
17 INT211839 Binding of EIF4E 8 0.36 0.79 0.18
18 INT287577 Positive_regulation of Transcription of Fmr1 2 0.48 2.5 0.16
19 INT257859 Negative_regulation of Eif4e 1 0.23 1.07 0.16
20 INT341192 Phosphorylation of Eif4e 1 0.49 0.36 0.1
21 INT204442 Regulation of Gene_expression of Fmr1 2 0.44 0.3 0.08
22 INT204466 Negative_regulation of Regulation of Fmr1 2 0.43 0.97 0.08
23 INT204458 Regulation of Positive_regulation of Fmr1 1 0.44 0.8 0.07
24 INT204457 Regulation of Binding of Fmr1 2 0.45 0.4 0.06
25 INT287587 Regulation of Negative_regulation of Fmr1 1 0.45 0.46 0.05
26 INT204460 Positive_regulation of Gene_expression of Fmr1 7 0.61 6.19 0.03
27 INT341167 Negative_regulation of Binding of Eif4e 1 0.33 0.23 0.03
28 INT341200 Negative_regulation of Eif4e 1 0.46 0.14 0.03
29 INT341189 Positive_regulation of Positive_regulation of Eif4e 1 0.36 0.13 0.03
30 INT227664 Phosphorylation of EIF4E 6 0.46 0.74 0
31 INT204446 Localization of Fmr1 5 0.79 1.12 0
32 INT204467 Negative_regulation of Binding of Fmr1 3 0.57 1.43 0
33 INT217806 Gene_expression of EIF4E 2 0.27 0.68 0
34 INT293778 Positive_regulation of EIF4E 2 0.45 0.42 0
35 INT287567 Negative_regulation of Negative_regulation of Fmr1 1 0.43 0.14 0
36 INT339011 Negative_regulation of Positive_regulation of Fmr1 1 0.43 2.18 0
37 INT293768 Regulation of Binding of EIF4E 1 0.18 0.13 0
38 INT341184 Positive_regulation of Localization of Eif4e 1 0.39 0 0
39 INT227668 Positive_regulation of Phosphorylation of EIF4E 1 0.20 0.15 0
40 INT276879 Regulation of Phosphorylation of EIF4E 1 0.25 0.21 0
41 INT293780 Positive_regulation of Binding of EIF4E 1 0.20 0.13 0
42 INT341191 Localization of Eif4e 1 0.63 0 0
43 INT287592 Positive_regulation of Regulation of Fmr1 1 0.50 0.61 0
44 INT341208 Negative_regulation of Binding of EIF4E 1 0.14 0 0
45 INT341188 Positive_regulation of Binding of Eif4e 1 0.34 0.18 0
46 INT293775 Regulation of EIF4E 1 0.24 0.64 0
47 INT293761 Negative_regulation of EIF4E 1 0.17 0.85 0
48 INT287579 Positive_regulation of Binding of Fmr1 1 0.50 0 0
49 INT351112 Positive_regulation of Positive_regulation of EIF4E 1 0.45 0.22 0
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