GO:0005883

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Name neurofilament
Categary Component
Go Slim No
Go Link GO:0005883
Unique Molecular Interactions 97
Total Molecular Interactions 172
Total Single Events 1151
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neurofilament. They are ordered first by their pain relevance and then by number of times they were reported for neurofilament. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64883 Ptger2 Positive_regulation of Ina 1 0.03 1.26 3.64
2 INT334532 Sema3a Negative_regulation of Gene_expression of Nrp1 1 0.19 7.58 2
3 INT208621 Binding of Prph and Nmbr 1 0.05 0.43 1.12
4 INT78976 Prkcg Regulation of Ina 1 0.13 0.16 0.93
5 INT78972 Prkaca Regulation of Ina 1 0.11 0.09 0.82
6 INT152857 PRS Regulation of Nefl 1 0.00 0.19 0.77
7 INT152833 Nefl Regulation of Prkcg 1 0.12 0.19 0.77
8 INT152831 Nefh Regulation of Prkcg 1 0.05 0.19 0.77
9 INT152832 Nefm Regulation of Nefh 1 0.12 0.19 0.77
10 INT152836 Nefm Regulation of Prkcg 1 0.15 0.19 0.77
11 INT152855 PRS Regulation of Nefh 1 0.00 0.19 0.77
12 INT152856 PRS Regulation of Nefm 1 0.00 0.19 0.77
13 INT152834 Nefl Regulation of Nefh 1 0.10 0.19 0.77
14 INT67887 SCN5A Negative_regulation of INA 1 0.02 0.13 0.71
15 INT260832 Binding of NRP2 and Nrp1 1 0.00 2.32 0.7
16 INT64884 Negative_regulation of Ptger2 Positive_regulation of Ina 1 0.03 0.24 0.65
17 INT78973 Prkcg Positive_regulation of Positive_regulation of Ina 1 0.10 0.07 0.55
18 INT68061 Binding of NA and Regulation of INA 1 0.09 0.08 0.46
19 INT78975 Positive_regulation of Prkaca Regulation of Ina 1 0.09 0 0.43
20 INT229507 Binding of Nefl and Ndel1 1 0.09 2.01 0.43
21 INT78971 Positive_regulation of Prkaca Positive_regulation of Ina 1 0.09 0.09 0.41
22 INT208623 Nmbr Positive_regulation of Prph 1 0.04 0.15 0.36
23 INT355038 NRP1 Negative_regulation of CKAP4 1 0.02 1.23 0.29
24 INT67969 Negative_regulation of Ina Negative_regulation of HMI 1 0.08 0 0.24
25 INT334522 Ngf Positive_regulation of Nrp1 1 0.19 0.93 0.22
26 INT334525 Ngf Positive_regulation of Gene_expression of Nrp1 1 0.19 0.93 0.22
27 INT4904 Oxt Regulation of Ina 1 0.03 0.08 0.21
28 INT5874 Pitx1 Positive_regulation of Ina 1 0.17 0 0.21
29 INT5873 Pitx1 Negative_regulation of Ina 1 0.15 0 0.21
30 INT172232 CALCRL Positive_regulation of Gene_expression of NRP1 1 0.02 0.07 0.17
31 INT172237 TAS2R14 Positive_regulation of Gene_expression of NRP1 1 0.01 0.07 0.17
32 INT232174 GAN Positive_regulation of ODT 1 0.01 0.98 0.14
33 INT334531 Nrp1 Negative_regulation of Gene_expression of Il4 1 0.08 0.48 0.14
34 INT291967 INA Positive_regulation of NA 1 0.00 0.98 0.14
35 INT334534 Nrp1 Negative_regulation of Gene_expression of Sema3a 1 0.17 0.48 0.14
36 INT334528 Nrp1 Negative_regulation of Sema3a 1 0.17 0.47 0.13
37 INT315205 Binding of Nefh and Cnp 1 0.24 1 0.09
38 INT315204 Binding of Epo and Nefh 1 0.26 1.01 0.09
39 INT229504 Negative_regulation of Binding of Nefl and Ndel1 1 0.08 0.33 0.09
40 INT229512 Binding of Nefl and Gopc 1 0.01 0.35 0.09
41 INT229495 Negative_regulation of Binding of Nefl and Gopc 1 0.02 0.35 0.09
42 INT337888 Ins1 Positive_regulation of Gene_expression of Ldlrap1 1 0.06 0 0.08
43 INT337889 Binding of Ins1 and Ldlrap1 1 0.06 0.27 0.08
44 INT229501 Binding of Nefl and Vim 1 0.05 0.32 0.08
45 INT243256 Binding of Nefl and Cfp 1 0.24 0.6 0.07
46 INT243258 Binding of Calb2 and Nefl 1 0.17 0.61 0.07
47 INT135641 Binding of Dst and Ina 1 0.35 0.34 0.06
48 INT173051 Binding of VEGFA and NRP1 16 0.44 1.29 0.04
49 INT173056 Binding of NRP2 and NRP1 2 0.24 0.61 0.04
50 INT265771 NRP1 Positive_regulation of VEGFA 1 0.46 0 0.04
51 INT265764 NRP1 Positive_regulation of FLT1 1 0.45 0 0.04
52 INT315915 VEGFA Regulation of NRP1 1 0.22 0.32 0.04
53 INT265772 Binding of KDR and NRP1 1 0.29 0 0.04
54 INT311926 Binding of NRP1 and SEMA3A 1 0.26 0.48 0.04
55 INT265749 Binding of FLT1 and NRP1 1 0.43 0 0.04
56 INT265744 VEGFA Regulation of Localization of NRP1 1 0.25 0 0
57 INT229511 Ndel1 Regulation of Binding of Nefl 1 0.09 0.31 0
58 INT225969 Binding of Aqp4 and Nefl 1 0.07 0.3 0
59 INT265767 Positive_regulation of Binding of VEGFA and NRP1 1 0.46 0 0
60 INT303896 Ina Regulation of NAA50 1 0.14 0.24 0
61 INT173054 NRP1 Positive_regulation of KDR 1 0.08 0.34 0
62 INT311948 Binding of NRP1 and Plxna3 1 0.05 0.26 0
63 INT265752 NRP1 Negative_regulation of Gene_expression of FLT1 1 0.33 0 0
64 INT216350 Binding of NEFM and NEFL 1 0.05 0.18 0
65 INT265765 Binding of NRP1 and GOPC 1 0.13 0 0
66 INT351678 Nrp1 Regulation of Binding of Ecm1 1 0.00 1.55 0
67 INT265737 Binding of AR and NRP1 1 0.10 0 0
68 INT265751 NRP1 Negative_regulation of Localization of FLT1 1 0.33 0 0
69 INT265756 Positive_regulation of Binding of AR and NRP1 1 0.10 0 0
70 INT196185 Binding of SEMA3A and Nrp1 1 0.01 0.05 0
71 INT265757 Regulation of Binding of VEGFA and NRP1 1 0.41 0 0
72 INT221638 Binding of Nrp1 and Sema3a 1 0.05 0.38 0
73 INT265738 NRP1 Positive_regulation of KLKB1 1 0.03 0 0
74 INT216349 Binding of NEFH and NEFL 1 0.05 0.18 0
75 INT265741 Negative_regulation of Binding of FLT1 and NRP1 1 0.38 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for neurofilament. They are ordered first by their pain relevance and then by number of times they were reported in neurofilament. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5440 Negative_regulation of Ina 85 0.58 10.52 28.98
2 INT6163 Negative_regulation of INA 39 0.43 2.9 14.8
3 INT13118 Positive_regulation of Ina 48 0.69 7.39 13.85
4 INT11996 Gene_expression of Ina 34 0.67 4.8 13.82
5 INT95500 Positive_regulation of Nefh 14 0.50 4.45 12.26
6 INT95495 Phosphorylation of Nefh 13 0.82 7.36 12.1
7 INT95492 Gene_expression of Nefh 20 0.67 12.68 10.46
8 INT4903 Regulation of Ina 23 0.50 3.03 9.46
9 INT95499 Negative_regulation of Nefh 9 0.59 8.97 7.13
10 INT13042 Gene_expression of INA 26 0.78 4.65 6.44
11 INT19995 Gene_expression of Prph 16 0.75 8.11 5.52
12 INT6164 Positive_regulation of INA 16 0.67 2.19 5.45
13 INT89546 Phosphorylation of NEFH 10 0.76 3.49 5.08
14 INT61118 Gene_expression of Nefl 11 0.75 4.02 4.02
15 INT109220 Positive_regulation of Phosphorylation of Nefh 1 0.30 0.61 3.84
16 INT69990 Negative_regulation of Nefl 11 0.59 2.82 3.38
17 INT135639 Gene_expression of Ina 3 0.76 9.58 2.89
18 INT23309 Negative_regulation of Positive_regulation of INA 2 0.38 0 2.88
19 INT89543 Gene_expression of NEFL 18 0.75 10.6 2.67
20 INT282877 Positive_regulation of Negative_regulation of INA 1 0.39 0 2.5
21 INT89137 Negative_regulation of Nefl 4 0.55 0.71 2.48
22 INT14282 Regulation of INA 5 0.23 0.87 2.42
23 INT95503 Regulation of Nefh 2 0.43 2.23 2.35
24 INT70297 Gene_expression of NEFH 12 0.75 4.85 2.33
25 INT12451 Positive_regulation of Nefm 3 0.46 0.86 2.25
26 INT240113 Gene_expression of Nrp1 11 0.30 10.88 2.24
27 INT56029 Gene_expression of Nefm 8 0.52 2.83 2.23
28 INT89551 Gene_expression of NEFM 13 0.44 4.74 2.22
29 INT50226 Negative_regulation of Negative_regulation of Ina 2 0.18 0.08 2.05
30 INT70210 Negative_regulation of NEFL 3 0.30 1.11 1.8
31 INT35391 Negative_regulation of Nefm 7 0.27 3.17 1.73
32 INT89542 Phosphorylation of NEFM 1 0.61 0.48 1.72
33 INT113676 Gene_expression of NRP1 22 0.72 10.81 1.71
34 INT13144 Regulation of Positive_regulation of Ina 5 0.22 0.4 1.67
35 INT95502 Localization of Nefh 4 0.70 0.84 1.64
36 INT94030 Binding of Nefh 3 0.48 1.93 1.57
37 INT95497 Positive_regulation of Gene_expression of Nefh 2 0.50 0.37 1.57
38 INT104731 Positive_regulation of NEFL 13 0.67 9.22 1.37
39 INT95501 Negative_regulation of Positive_regulation of Nefh 1 0.43 0.08 1.28
40 INT95498 Negative_regulation of Negative_regulation of Nefh 1 0.43 0.08 1.27
41 INT95493 Positive_regulation of Localization of Nefh 1 0.47 0.08 1.27
42 INT55289 Positive_regulation of Gene_expression of INA 2 0.67 0.22 1.19
43 INT109218 Negative_regulation of Phosphorylation of Nefh 2 0.36 0.76 1.19
44 INT282878 Localization of INA 3 0.59 1.51 1.12
45 INT282875 Negative_regulation of Gene_expression of INA 1 0.33 0 1.11
46 INT95496 Positive_regulation of Positive_regulation of Nefh 1 0.50 0.09 1.1
47 INT95494 Phosphorylation of Nefm 2 0.40 0.48 1.08
48 INT70300 Negative_regulation of NEFH 2 0.54 0.37 1.05
49 INT152125 Negative_regulation of Gene_expression of Prph 6 0.57 3.28 1.01
50 INT30886 Positive_regulation of Ina 5 0.62 1.35 0.96
51 INT310857 Positive_regulation of Gene_expression of Prph 1 0.14 1.89 0.96
52 INT89547 Negative_regulation of Gene_expression of NEFL 2 0.36 0.57 0.95
53 INT42819 Positive_regulation of Negative_regulation of Ina 4 0.40 0.07 0.92
54 INT152841 Positive_regulation of Nefl 2 0.28 0.38 0.92
55 INT30885 Positive_regulation of Nefl 6 0.36 6.99 0.9
56 INT135635 Binding of Ina 2 0.41 8.28 0.88
57 INT89552 Positive_regulation of NEFM 1 0.34 0.23 0.87
58 INT89545 Positive_regulation of Phosphorylation of NEFM 1 0.34 0.23 0.87
59 INT89550 Positive_regulation of Gene_expression of NEFM 1 0.34 0.23 0.87
60 INT89549 Positive_regulation of NEFH 2 0.43 1.42 0.86
61 INT89544 Phosphorylation of NEFL 2 0.79 1.05 0.86
62 INT149291 Negative_regulation of NRP1 5 0.40 2.64 0.84
63 INT149298 Protein_catabolism of NRP1 2 0.82 1.52 0.77
64 INT49593 Regulation of Prph 2 0.26 0.93 0.73
65 INT355995 Positive_regulation of Prph 1 0.21 1 0.73
66 INT318458 Transcription of Prph 1 0.22 0.77 0.72
67 INT139205 Binding of NRP1 27 0.45 4.34 0.71
68 INT3536 Positive_regulation of Nrp1 2 0.19 0.93 0.7
69 INT89548 Negative_regulation of Phosphorylation of NEFH 1 0.40 0.1 0.7
70 INT265800 Localization of NRP1 14 0.75 3.66 0.69
71 INT196155 Binding of Nrp1 5 0.16 2.38 0.69
72 INT69989 Negative_regulation of Gene_expression of Nefl 2 0.43 0.44 0.67
73 INT64882 Positive_regulation of Regulation of Ina 1 0.07 0.35 0.67
74 INT260823 Positive_regulation of Gene_expression of Nrp1 3 0.19 2.14 0.65
75 INT22714 Binding of Nefl 1 0.32 0 0.64
76 INT57429 Localization of Ina 6 0.50 0 0.62
77 INT65616 Binding of Ina 3 0.08 0 0.6
78 INT208612 Binding of Prph 2 0.12 0.54 0.57
79 INT58084 Regulation of Nefm 2 0.17 0.41 0.54
80 INT183172 Positive_regulation of Gene_expression of Ina 5 0.34 0.94 0.53
81 INT194335 Gene_expression of Nefl 15 0.51 5.64 0.51
82 INT238699 Negative_regulation of Gene_expression of Ina 1 0.29 0 0.51
83 INT82335 Negative_regulation of Ina 3 0.36 1.11 0.5
84 INT79935 Negative_regulation of Nrp1 3 0.17 1.36 0.46
85 INT68062 Regulation of Gene_expression of INA 1 0.23 0 0.46
86 INT356335 Positive_regulation of Localization of INA 1 0.19 4.21 0.45
87 INT288505 Regulation of Regulation of Nefh 1 0.26 0.91 0.45
88 INT70302 Transcription of NEFH 3 0.66 0.24 0.44
89 INT149293 Negative_regulation of Protein_catabolism of NRP1 1 0.05 0.93 0.44
90 INT288508 Negative_regulation of Gene_expression of Nefh 1 0.49 1.62 0.42
91 INT159651 Negative_regulation of GAN 1 0.41 1.1 0.4
92 INT159650 Gene_expression of GAN 1 0.65 1.11 0.4
93 INT159649 Negative_regulation of Gene_expression of GAN 1 0.41 1.11 0.4
94 INT81624 Positive_regulation of Gene_expression of Nefm 2 0.40 1.3 0.37
95 INT243089 Gene_expression of Ldlrap1 2 0.65 0.14 0.35
96 INT143442 Positive_regulation of NRP1 11 0.57 2.62 0.3
97 INT238698 Regulation of Gene_expression of Ina 1 0.30 0 0.29
98 INT95476 Localization of NEFL 2 0.33 0.42 0.28
99 INT179967 Regulation of Ina 2 0.38 0.32 0.28
100 INT86055 Transcription of Nefl 1 0.12 0.09 0.28
101 INT140122 Transcription of Nefl 3 0.62 0.16 0.27
102 INT288504 Negative_regulation of Regulation of Nefh 1 0.42 0.52 0.26
103 INT264305 Negative_regulation of Gene_expression of NRP1 3 0.40 1.4 0.25
104 INT288507 Regulation of Gene_expression of Nefh 1 0.38 0.48 0.24
105 INT57428 Positive_regulation of Localization of Ina 1 0.34 0 0.2
106 INT70299 Negative_regulation of Transcription of NEFH 1 0.40 0.12 0.19
107 INT140124 Transcription of Nefh 1 0.62 0.16 0.19
108 INT140125 Transcription of Nefm 1 0.62 0.16 0.19
109 INT333077 Localization of NEFM 1 0.05 1.99 0.19
110 INT288506 Negative_regulation of Localization of Nefh 1 0.36 0.37 0.18
111 INT70301 Regulation of Gene_expression of NEFH 1 0.56 0.11 0.18
112 INT291970 Binding of INA 2 0.16 0.52 0.17
113 INT315717 Positive_regulation of Gene_expression of Ina 1 0.59 1.67 0.17
114 INT142818 Regulation of GAN 1 0.44 0.41 0.16
115 INT315715 Negative_regulation of Binding of Ina 1 0.42 1.68 0.16
116 INT356334 Regulation of Localization of INA 1 0.17 1.54 0.15
117 INT229457 Binding of Nefl 1 0.07 0.98 0.15
118 INT356339 Negative_regulation of Localization of INA 1 0.16 1.4 0.15
119 INT243075 Regulation of Gene_expression of Ldlrap1 2 0.44 0.15 0.13
120 INT265792 Regulation of Localization of NRP1 1 0.22 0.21 0.13
121 INT265797 Regulation of Protein_catabolism of NRP1 1 0.51 0.21 0.13
122 INT337866 Binding of Ldlrap1 1 0.18 0.56 0.12
123 INT143446 Positive_regulation of Gene_expression of NRP1 1 0.45 1.02 0.12
124 INT70298 Regulation of NEFH 1 0.41 0.1 0.12
125 INT339798 Transcription of Ina 1 0.07 0.06 0.11
126 INT35392 Binding of Nefm 1 0.23 0.17 0.11
127 INT137830 Binding of NEFH 2 0.32 1.13 0.1
128 INT356338 Regulation of Phosphorylation of INA 1 0.17 0.7 0.08
129 INT356337 Phosphorylation of INA 1 0.31 0.7 0.08
130 INT140120 Positive_regulation of Transcription of Nefl 1 0.43 0.09 0.08
131 INT137829 Negative_regulation of Gene_expression of NEFH 1 0.38 0.31 0.08
132 INT140123 Positive_regulation of Transcription of Nefh 1 0.43 0.09 0.08
133 INT315716 Localization of Ina 1 0.68 1.01 0.08
134 INT140121 Positive_regulation of Transcription of Nefm 1 0.60 0.09 0.08
135 INT356336 Positive_regulation of Phosphorylation of INA 1 0.19 0.77 0.08
136 INT144613 Regulation of NEFL 2 0.31 1.55 0.07
137 INT229474 Positive_regulation of Gene_expression of Nefl 1 0.09 0.32 0.07
138 INT229477 Negative_regulation of Gene_expression of Nefl 1 0.08 0.32 0.07
139 INT229453 Positive_regulation of Positive_regulation of Nefl 1 0.08 0.22 0.06
140 INT137130 Positive_regulation of Positive_regulation of Nefm 1 0.32 0.24 0.06
141 INT208616 Positive_regulation of Binding of Prph 1 0.08 0 0.06
142 INT182679 Positive_regulation of Gene_expression of NEFH 2 0.34 0.17 0.05
143 INT135636 Negative_regulation of Positive_regulation of Ina 1 0.38 0.33 0.05
144 INT261207 Binding of NEFL 2 0.06 1.09 0.04
145 INT315719 Regulation of Localization of Ina 1 0.23 0.51 0.04
146 INT238697 Regulation of Localization of Ina 2 0.30 0 0.03
147 INT315718 Positive_regulation of Positive_regulation of Ina 1 0.59 0.37 0.03
148 INT192589 Negative_regulation of NEFM 1 0.00 1.13 0.03
149 INT243236 Localization of Nefl 3 0.73 1.57 0
150 INT235629 Phosphorylation of NRP1 2 0.76 0.81 0
151 INT249340 Localization of NEFH 1 0.29 0.59 0
152 INT113675 Regulation of Gene_expression of NRP1 1 0.00 1.62 0
153 INT272795 Negative_regulation of Gene_expression of NEFM 1 0.04 0.45 0
154 INT70608 Positive_regulation of Protein_catabolism of Nefm 1 0.18 0.43 0
155 INT315923 Negative_regulation of Positive_regulation of NRP1 1 0.40 0.19 0
156 INT73282 Regulation of Negative_regulation of INA 1 0.03 0 0
157 INT275207 Binding of NEFM 1 0.01 0.5 0
158 INT70607 Protein_catabolism of Nefm 1 0.26 0.43 0
159 INT182680 Positive_regulation of Gene_expression of NEFL 1 0.22 0.16 0
160 INT302041 Negative_regulation of Gene_expression of Nrp1 1 0.07 0.14 0
161 INT282041 Positive_regulation of Positive_regulation of Ina 1 0.07 0 0
162 INT249341 Positive_regulation of Localization of NEFH 1 0.18 0.59 0
163 INT265785 Positive_regulation of Localization of NRP1 1 0.41 0 0
164 INT243249 Regulation of Nefl 1 0.18 3.85 0
165 INT265793 Regulation of NRP1 1 0.22 0 0
166 INT353775 Negative_regulation of Ldlrap1 1 0.02 1 0
167 INT265798 Positive_regulation of Binding of NRP1 1 0.41 0 0
168 INT243095 Positive_regulation of Ldlrap1 1 0.49 0.18 0
169 INT243072 Transcription of Ldlrap1 1 0.67 0 0
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