GO:0005891

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Name voltage-gated calcium channel complex
Categary Component
Go Slim No
Go Link GO:0005891
Unique Molecular Interactions 118
Total Molecular Interactions 168
Total Single Events 1217
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for voltage-gated calcium channel complex. They are ordered first by their pain relevance and then by number of times they were reported for voltage-gated calcium channel complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
2 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
3 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08
4 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
5 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
6 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
7 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
8 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
9 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
10 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
11 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34
12 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
13 INT74841 Binding of Cacna1a and Ea2 2 0.01 2.33 1.27
14 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
15 INT108729 Binding of CACNA1A and Cacna1a 3 0.13 1.21 0.95
16 INT336835 Binding of CACNG6 and Aia1 1 0.01 3.41 0.75
17 INT123077 Cacna1c Negative_regulation of Gene_expression of Dbi 1 0.05 0.71 0.7
18 INT214410 Binding of ATP1A4 and CACNA1A 1 0.26 0.95 0.7
19 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
20 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
21 INT244021 Positive_regulation of Binding of Cacnb3 and Prkaca 1 0.02 0.24 0.49
22 INT244036 Binding of Cacnb3 and Prkaca 1 0.01 0.24 0.49
23 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
24 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49
25 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45
26 INT155752 Binding of CACNA1A and ATCAY 1 0.04 0.86 0.42
27 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4
28 INT158355 Cacna1a Regulation of Alox5 1 0.01 0.7 0.37
29 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34
30 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34
31 INT101551 Binding of CACNA1A and CACNA1F 1 0.07 1.51 0.33
32 INT151258 Binding of Cacna1a and FCMTE1 1 0.00 0.57 0.3
33 INT77753 Abnormal Regulation of CACNA1S 1 0.00 0.78 0.28
34 INT142003 Binding of Cacna1a and Etax2 1 0.00 1.02 0.26
35 INT142004 Binding of Cacna1a and TGM6 1 0.00 1.02 0.26
36 INT354519 Cacna1c Regulation of Mri1 1 0.00 1.15 0.21
37 INT121807 CACNA1A Regulation of CAV2 1 0.01 0.25 0.2
38 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16
39 INT303866 Positive_regulation of NAA50 Negative_regulation of Gene_expression of CACNA1C 1 0.13 0.08 0.16
40 INT71329 Cacna1a Regulation of Ea2 1 0.01 0.71 0.15
41 INT71328 Cacna1a Regulation of Atxn2 1 0.00 0.71 0.15
42 INT244065 Negative_regulation of Bdnf Positive_regulation of Phosphorylation of Cacnb3 1 0.04 0.1 0.15
43 INT120559 Binding of Cacna1a and FCMTE1 1 0.02 0.25 0.1
44 INT196213 REST Regulation of Gene_expression of CACNA1A 1 0.46 0.08 0.08
45 INT236531 Binding of Cacna1f and Flna 1 0.08 0 0.07
46 INT111933 Cacna1c Positive_regulation of PENK 1 0.01 0 0.07
47 INT254463 Binding of Camk2a and Cacna1c 1 0.00 0.17 0.06
48 INT244041 Binding of Cacnb3 and Gabrg1 1 0.03 0 0.05
49 INT354983 Cacna1a Regulation of Mpo 1 0.02 0.41 0.04
50 INT354987 Cacna1a Regulation of Localization of LDHA 1 0.00 0.23 0.03
51 INT315034 Ass1 Positive_regulation of Cacna1f 1 0.00 0 0.03
52 INT329993 Binding of CACNA1C and KCNMA1 1 0.32 0.19 0
53 INT196208 REST Regulation of CACNA1A 1 0.46 0.06 0
54 INT325589 Nppa Regulation of Cacna1c 1 0.05 0 0
55 INT196216 Binding of CACNA1A and REST 1 0.28 0 0
56 INT261963 Binding of Cacna1a and Tgm2 1 0.08 1.19 0
57 INT250496 Gopc Regulation of Positive_regulation of Cacna1a 1 0.37 0 0
58 INT314986 Ins1 Negative_regulation of CACNA1S 1 0.00 0.08 0
59 INT241443 Binding of Tgtp1 and Cacna1d 1 0.00 0 0
60 INT315029 Binding of Calm3 and Cacna1f 1 0.04 0 0
61 INT336179 Binding of CACNA1F and DLST 1 0.01 1.6 0
62 INT315031 Binding of Cacna1f and Vsig2 1 0.02 0 0
63 INT336829 RS1 Regulation of CACNG6 1 0.15 0.15 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for voltage-gated calcium channel complex. They are ordered first by their pain relevance and then by number of times they were reported in voltage-gated calcium channel complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
2 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
3 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
4 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
5 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43
6 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91
7 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65
8 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37
9 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13
10 INT110796 Positive_regulation of Positive_regulation of Cacna1a 1 0.49 0.51 4.84
11 INT82731 Transcription of Cacna1a 5 0.56 3.41 4.27
12 INT287526 Negative_regulation of Gene_expression of CACNA1A 1 0.42 4.25 3.81
13 INT48122 Regulation of Cacna1h 5 0.42 3 3.37
14 INT53516 Binding of CACNA1A 9 0.47 6.86 3.36
15 INT167913 Gene_expression of CACNA1C 3 0.75 0.38 3.34
16 INT94045 Regulation of Cacna1a 5 0.42 3.56 3.33
17 INT78317 Regulation of CACNA1A 8 0.62 7.68 3.08
18 INT85572 Gene_expression of Cacna1a 11 0.66 5.72 3.02
19 INT142940 Positive_regulation of Negative_regulation of Cacna1a 3 0.50 1.65 2.97
20 INT86341 Positive_regulation of Cacnb3 3 0.44 0.91 2.79
21 INT355244 Negative_regulation of Negative_regulation of Cacna1a 1 0.04 0 2.67
22 INT161575 Localization of CACNA1A 4 0.75 5.28 2.26
23 INT19286 Negative_regulation of Cacna1c 11 0.46 5.12 2.22
24 INT48120 Positive_regulation of Cacna1h 5 0.34 1.2 2.22
25 INT110795 Regulation of Positive_regulation of Cacna1a 2 0.26 0.65 2.07
26 INT112368 Positive_regulation of Cacna1c 8 0.46 2.94 1.97
27 INT354979 Positive_regulation of Localization of Cacna1a 2 0.05 0.86 1.79
28 INT355239 Negative_regulation of Positive_regulation of Cacna1a 1 0.04 0 1.79
29 INT71327 Localization of Cacna1a 3 0.60 2.51 1.7
30 INT123076 Gene_expression of Cacna1c 7 0.37 1.91 1.56
31 INT15048 Regulation of Cacna1c 4 0.29 3.26 1.47
32 INT355242 Negative_regulation of Binding of Cacna1a 1 0.04 0.17 1.47
33 INT65452 Negative_regulation of Cacna1c 8 0.09 0.8 1.44
34 INT355245 Regulation of Localization of Cacna1a 1 0.04 0 1.43
35 INT90740 Negative_regulation of Cacna1a 3 0.23 1.43 1.38
36 INT86342 Negative_regulation of Cacnb3 1 0.40 0.41 1.38
37 INT77752 Binding of Cacna1c 3 0.22 0.22 1.31
38 INT48121 Negative_regulation of Cacna1h 3 0.11 1.86 1.28
39 INT82727 Positive_regulation of Transcription of Cacna1a 1 0.01 1.07 1.25
40 INT85571 Positive_regulation of Cacna1a 3 0.50 2.06 1.18
41 INT355243 Negative_regulation of Regulation of Cacna1a 1 0.04 0 1.16
42 INT66452 Positive_regulation of Cacna1c 6 0.19 2.56 1.08
43 INT336832 Gene_expression of CACNG6 1 0.78 2.88 1.01
44 INT336833 Binding of CACNG6 1 0.37 6.91 0.99
45 INT78935 Localization of Cacna1c 3 0.48 1.25 0.97
46 INT321650 Negative_regulation of Gene_expression of Cacna1a 2 0.04 0.13 0.95
47 INT94046 Protein_catabolism of Cacna1a 1 0.70 0.83 0.9
48 INT131964 Positive_regulation of CACNA1A 5 0.61 0.73 0.85
49 INT77610 Gene_expression of Cacna1h 6 0.65 0.47 0.8
50 INT236517 Gene_expression of Cacna1f 8 0.65 5.18 0.77
51 INT76487 Localization of Cacna1h 3 0.48 0.98 0.77
52 INT108765 Binding of Cacna1d 1 0.06 0 0.74
53 INT123075 Positive_regulation of Gene_expression of Cacna1c 1 0.05 0.73 0.73
54 INT68589 Gene_expression of Cacna1c 14 0.58 6.36 0.69
55 INT70104 Positive_regulation of CACNA1S 6 0.47 5.92 0.68
56 INT103336 Transcription of Cacna1a 2 0.69 1.17 0.68
57 INT141227 Phosphorylation of CACNA1A 1 0.55 0.78 0.66
58 INT189813 Negative_regulation of CACNA1A 4 0.57 3.07 0.55
59 INT122930 Positive_regulation of Gene_expression of CACNA1A 2 0.49 0.91 0.54
60 INT243917 Binding of Cacnb3 1 0.05 0.24 0.49
61 INT96574 Transcription of Cacna1h 1 0.05 0.29 0.42
62 INT130556 Binding of CACNA1C 3 0.22 1.84 0.4
63 INT303879 Positive_regulation of Gene_expression of CACNA1C 2 0.49 0.08 0.34
64 INT99962 Positive_regulation of Gene_expression of Cacna1a 1 0.01 1.1 0.34
65 INT155753 Regulation of Gene_expression of CACNA1A 1 0.27 0.66 0.32
66 INT101552 Binding of CACNA1F 2 0.17 1.95 0.26
67 INT264627 Positive_regulation of CACNA1C 1 0.22 0.1 0.26
68 INT243910 Phosphorylation of Cacnb3 1 0.11 0.06 0.24
69 INT101742 Regulation of Cacna1c 3 0.22 1.35 0.23
70 INT246083 Positive_regulation of Cacna1d 1 0.02 0.89 0.22
71 INT224030 Localization of Cacna1c 1 0.01 2.01 0.18
72 INT101741 Binding of Cacna1c 3 0.28 1.49 0.17
73 INT296813 Positive_regulation of Gene_expression of Cacna1h 1 0.06 0.19 0.17
74 INT315024 Positive_regulation of Cacna1f 1 0.41 0.5 0.17
75 INT216261 Regulation of Gene_expression of Cacna1c 3 0.25 1.12 0.15
76 INT199810 Positive_regulation of Gene_expression of Cacna1c 2 0.43 0.81 0.13
77 INT315027 Positive_regulation of Gene_expression of Cacna1f 1 0.41 0.27 0.12
78 INT250736 Protein_catabolism of Cacna1c 1 0.14 0.06 0.12
79 INT172390 Negative_regulation of Gene_expression of Cacna1c 2 0.17 2.33 0.11
80 INT16175 Positive_regulation of CACNA1F 2 0.11 2.75 0.1
81 INT236521 Negative_regulation of Cacna1f 2 0.36 0.07 0.09
82 INT196235 Negative_regulation of Transcription of CACNA1A 1 0.36 0.1 0.07
83 INT196229 Transcription of CACNA1A 1 0.60 0.24 0.07
84 INT170506 Positive_regulation of Positive_regulation of Cacna1c 1 0.04 0.09 0.05
85 INT108117 Regulation of CACNA1S 1 0.39 0.25 0.05
86 INT309389 Phosphorylation of Cacna1a 1 0.01 0.54 0.05
87 INT172389 Regulation of Binding of Cacna1c 1 0.07 0.19 0.05
88 INT309386 Positive_regulation of Phosphorylation of Cacna1a 1 0.01 0.54 0.05
89 INT207781 Gene_expression of CACNA1S 3 0.63 0.9 0.03
90 INT170512 Regulation of Gene_expression of Cacna1c 1 0.04 0.1 0.03
91 INT207782 Binding of CACNA1S 1 0.30 0.53 0.03
92 INT236525 Binding of Cacna1f 5 0.39 0.07 0
93 INT236516 Regulation of Cacna1f 3 0.44 0.23 0
94 INT236526 Phosphorylation of Cacna1f 1 0.79 0 0
95 INT236522 Negative_regulation of Phosphorylation of Cacna1f 1 0.41 0 0
96 INT325563 Negative_regulation of Positive_regulation of Cacna1c 1 0.05 0 0
97 INT333531 Regulation of CACNA1C 1 0.60 0.69 0
98 INT315019 Regulation of Binding of Cacna1f 1 0.37 0.07 0
99 INT243942 Negative_regulation of Gene_expression of Cacnb3 1 0.05 0 0
100 INT325551 Positive_regulation of Negative_regulation of Cacna1c 1 0.06 0 0
101 INT196237 Positive_regulation of Transcription of CACNA1A 1 0.39 0.14 0
102 INT243920 Gene_expression of Cacnb3 1 0.08 0 0
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