GO:0005901

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Name caveola
Categary Component
Go Slim No
Go Link GO:0005901
Unique Molecular Interactions 1729
Total Molecular Interactions 2329
Total Single Events 20451
Pain Genes Associated 108

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for caveola. They are ordered first by their pain relevance and then by number of times they were reported for caveola. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
2 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
3 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
4 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
5 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
6 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
7 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
8 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
9 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
10 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
11 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
12 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
13 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
14 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
15 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
16 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
17 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
18 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
19 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 0.14 0 1.7
20 INT105917 Binding of SLC22A6 and SLC22A8 2 0.31 0.34 1.67
21 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
22 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
23 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
24 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
25 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
26 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
27 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
28 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
29 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
30 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
31 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
32 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
33 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
34 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
35 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
36 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34
37 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
38 INT162165 WDTC1 Positive_regulation of PLD2 1 0.50 0 1.25
39 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
40 INT305408 Binding of KCNMA1 and ST8SIA2 1 0.01 0.09 1.24
41 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
42 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
43 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
44 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
45 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
46 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
47 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
48 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
49 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
50 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
51 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
52 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
53 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
54 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
55 INT139736 Htr1a Positive_regulation of Mapk3 1 0.54 0.13 1.19
56 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
57 INT62382 Binding of IGHG3 and SMPD2 1 0.02 0.37 1.17
58 INT62379 Negative_regulation of Binding of IGHG3 and SMPD2 1 0.03 0.37 1.17
59 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
60 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
61 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16
62 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
63 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
64 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
65 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
66 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
67 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
68 INT74185 Cck Negative_regulation of Drd1a 1 0.30 0.1 1.1
69 INT164378 MAPK3 Positive_regulation of Transcription of PDYN 1 0.50 0.2 1.09
70 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
71 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
72 INT107938 POMC Positive_regulation of Gene_expression of TGFBR2 1 0.42 1.09 1.07
73 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
74 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
75 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
76 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
77 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
78 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
79 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
80 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
81 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
82 INT320021 Prkaca Regulation of Positive_regulation of Kcnma1 1 0.00 0.54 1
83 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
84 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99
85 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99
86 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
87 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
88 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
89 INT128602 Binding of Kcnma1 and Gtf2ird2 1 0.00 0 0.97
90 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
91 INT87854 Binding of Drd1a and Positive_regulation of Localization of Abat 1 0.08 0 0.96
92 INT74184 Cck Regulation of Localization of Drd1a 1 0.32 0.06 0.95
93 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
94 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
95 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
96 INT144551 Binding of Lrp8 and Sepp1 1 0.55 1.73 0.93
97 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
98 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
99 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
100 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92
101 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
102 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
103 INT136172 NPY Negative_regulation of Positive_regulation of Drd1a 1 0.21 0 0.91
104 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
105 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9
106 INT7292 Binding of Drd1a and Penk 1 0.14 0 0.9
107 INT52760 Oprd1 Regulation of Drd1a 1 0.02 0 0.9
108 INT112642 Positive_regulation of Kcnma1 Positive_regulation of Nav1 1 0.02 0 0.89
109 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
110 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
111 INT97738 Mdk Positive_regulation of Mapk3 1 0.08 0.66 0.87
112 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
113 INT97735 Trib3 Positive_regulation of Mapk3 1 0.05 0.66 0.87
114 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
115 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86
116 INT305406 Binding of CAV3 and ST8SIA2 1 0.16 0 0.86
117 INT130769 FASLG Negative_regulation of Binding of FAS 1 0.10 0.66 0.86
118 INT146495 Snta1 Positive_regulation of Adrbk1 1 0.14 0.68 0.85
119 INT42865 Binding of Adrb2 and Man2a2 1 0.23 1.03 0.85
120 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85
121 INT42864 Regulation of Binding of Adrb2 and Man2a2 1 0.28 1.03 0.85
122 INT29279 Binding of Drd1a and Htr1a 1 0.35 0.2 0.84
123 INT110236 Hk1 Regulation of CSAD 1 0.01 1.57 0.84
124 INT344101 Positive_regulation of Drd1a Positive_regulation of Localization of Abat 1 0.01 0 0.84
125 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84
126 INT102931 Nos3 Positive_regulation of Nos2 1 0.43 1.63 0.83
127 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82
128 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
129 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
130 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
131 INT102932 Nos3 Positive_regulation of NOS1 1 0.03 1.63 0.82
132 INT54559 KCNMA1 Positive_regulation of Localization of TBXA2R 1 0.01 0.07 0.81
133 INT107937 POMC Regulation of Gene_expression of TGFBR2 1 0.28 0.82 0.81
134 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79
135 INT114068 Agtr2 Regulation of Gene_expression of Insr 1 0.15 0.95 0.79
136 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
137 INT107739 Prkcg Negative_regulation of Positive_regulation of Pld2 1 0.46 0 0.79
138 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
139 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
140 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
141 INT124384 ADRBK1 Negative_regulation of MC1R 1 0.40 0.42 0.77
142 INT353721 Negative_regulation of Binding of Drd1a and Ghsr 1 0.16 0 0.76
143 INT353720 Binding of Drd1a and Ghsr 1 0.18 0 0.76
144 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
145 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
146 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
147 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
148 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
149 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
150 INT21260 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.05 0 0.76
151 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74
152 INT133675 NPY6R Negative_regulation of SRC 1 0.17 0.75 0.74
153 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
154 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73
155 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
156 INT228499 Binding of FAS and Fasl 1 0.15 2.75 0.73
157 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72
158 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
159 INT148453 Gene_expression of Inhbe Positive_regulation of Src 1 0.06 0.68 0.72
160 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71
161 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
162 INT338057 Positive_regulation of F2r Positive_regulation of Localization of Calca 1 0.05 0.28 0.71
163 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
164 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
165 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7
166 INT107741 Binding of OPRM1 and Pld2 1 0.01 0 0.69
167 INT99938 Drd1a Regulation of Transcription of Qrfp 1 0.03 0 0.69
168 INT140235 ADRBK1 Positive_regulation of Binding of MC1R 1 0.46 0.31 0.68
169 INT99743 Olr1742 Regulation of Gene_expression of Hmox1 1 0.00 0 0.68
170 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68
171 INT99939 Drd1a Regulation of Qrfp 1 0.03 0 0.68
172 INT140237 Gene_expression of ADRBK1 Positive_regulation of Gene_expression of MC1R 1 0.46 0.31 0.68
173 INT134286 PLD2 Regulation of Regulation of EDNRA 1 0.10 0 0.67
174 INT134287 PLD2 Regulation of Regulation of MRGPRX1 1 0.31 0 0.67
175 INT150338 Binding of F2 and F2R 1 0.11 0.4 0.67
176 INT220032 Nos1 Positive_regulation of Nos3 1 0.32 0.45 0.66
177 INT334128 Acsm3 Positive_regulation of Sele 1 0.16 1.6 0.66
178 INT211915 Fig4 Positive_regulation of Mapk3 1 0.12 0.25 0.66
179 INT86519 Binding of Hmox1 and Hmox2 1 0.08 0.1 0.66
180 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66
181 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
182 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
183 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
184 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
185 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65
186 INT115811 Binding of Slc22a6 and Mtx1 1 0.02 0.17 0.65
187 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64
188 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64
189 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64
190 INT99744 Calca Positive_regulation of Positive_regulation of Hmox1 1 0.48 0 0.64
191 INT103870 IRF6 Positive_regulation of Hmox1 1 0.14 0.83 0.64
192 INT176476 TNF Positive_regulation of Gene_expression of SELE 1 0.04 0.57 0.63
193 INT169296 PTPLA Positive_regulation of MAPK3 1 0.10 0.15 0.63
194 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63
195 INT160880 Pld2 Positive_regulation of Oprm1 1 0.07 0.08 0.63
196 INT160882 Pld2 Positive_regulation of Gene_expression of Oprm1 1 0.06 0.08 0.63
197 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
198 INT139079 Tnip1 Negative_regulation of Ptch1 1 0.20 0.63 0.62
199 INT71942 Negative_regulation of PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.62
200 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62

Single Events

The table below shows the top 100 pain related interactions that have been reported for caveola. They are ordered first by their pain relevance and then by number of times they were reported in caveola. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
2 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
3 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
4 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
5 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
6 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
7 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
8 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
9 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
10 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
11 INT5858 Positive_regulation of Drd1a 66 0.69 4.51 51.73
12 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
13 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
14 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
15 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
16 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56
17 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46
18 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92
19 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
20 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05
21 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
22 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17
23 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
24 INT8691 Localization of Insr 85 0.80 9.27 30.32
25 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27
26 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
27 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56
28 INT5300 Regulation of Insr 54 0.60 11.33 29.26
29 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
30 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85
31 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
32 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11
33 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43
34 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19
35 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
36 INT13838 Positive_regulation of Drd1a 48 0.70 9.83 23.42
37 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92
38 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
39 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
40 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
41 INT17848 Binding of PTGS2 70 0.46 32.1 20.6
42 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
43 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41
44 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
45 INT7680 Regulation of Drd1a 27 0.45 4.52 18.86
46 INT118512 Gene_expression of F2r 33 0.63 26.56 18.26
47 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88
48 INT61257 Gene_expression of Sele 79 0.77 70.97 17.78
49 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71
50 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64
51 INT51779 Gene_expression of Drd1a 46 0.66 11.18 17.51
52 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15
53 INT7020 Negative_regulation of Drd1a 25 0.57 1.84 17.1
54 INT5859 Positive_regulation of Positive_regulation of Drd1a 20 0.55 2.05 15.61
55 INT52591 Gene_expression of KCNMA1 78 0.76 13.95 15.55
56 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
57 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38
58 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44
59 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
60 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01
61 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
62 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52
63 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
64 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99
65 INT48927 Regulation of Mapk3 25 0.60 14.06 12.82
66 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8
67 INT121242 Positive_regulation of Gene_expression of Nos3 37 0.69 31.96 12.71
68 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
69 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39
70 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
71 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04
72 INT7682 Binding of Drd1a 22 0.48 1.8 11.83
73 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
74 INT73431 Positive_regulation of Nos3 82 0.65 53.22 11.61
75 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39
76 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
77 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
78 INT36715 Gene_expression of Trpc4 50 0.68 4.18 11.13
79 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92
80 INT11479 Positive_regulation of KCNMA1 30 0.68 10.07 10.82
81 INT54706 Regulation of Adrbk1 11 0.62 0.89 10.69
82 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
83 INT48921 Regulation of Mapk1 25 0.49 19.51 10.41
84 INT7458 Negative_regulation of Kcnma1 30 0.43 6.61 10.4
85 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39
86 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
87 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71
88 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53
89 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51
90 INT86851 Gene_expression of Faslg 45 0.75 24.42 9.21
91 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
92 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
93 INT109432 Negative_regulation of Phosphorylation of Mapk1 19 0.54 7.01 8.98
94 INT111133 Negative_regulation of Mapk3 31 0.57 10.89 8.9
95 INT29411 Positive_regulation of ADRB2 13 0.65 5.42 8.78
96 INT3622 Regulation of CTSB 34 0.58 16.08 8.76
97 INT168096 Transcription of Cav3 1 0.72 7.23 8.58
98 INT16735 Localization of Drd1a 11 0.61 0.35 8.42
99 INT15592 Positive_regulation of F2r 17 0.67 8.66 8.36
100 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34
101 INT71785 Gene_expression of MAPK3 22 0.75 11.35 8.21
102 INT117497 Positive_regulation of F2r 18 0.57 14.45 8.13
103 INT82450 Negative_regulation of Hmox1 33 0.55 19.07 8.12
104 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
105 INT82762 Positive_regulation of Positive_regulation of Mapk3 23 0.67 7.72 7.91
106 INT81345 Gene_expression of ADRBK1 21 0.70 2.89 7.9
107 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87
108 INT172789 Regulation of Gene_expression of Nos3 15 0.53 16.23 7.86
109 INT72372 Positive_regulation of Phosphorylation of Mapk3 30 0.67 13.6 7.69
110 INT91618 Positive_regulation of Phosphorylation of MAPK3 21 0.67 7.99 7.65
111 INT65246 Negative_regulation of Nos3 36 0.50 25.65 7.62
112 INT84162 Negative_regulation of KCNMA1 26 0.58 5.05 7.58
113 INT7168 Positive_regulation of Ctsb 9 0.70 0.3 7.58
114 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
115 INT95133 Gene_expression of FASLG 38 0.75 44.09 7.51
116 INT7883 Binding of ADRB2 18 0.47 5.49 7.37
117 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
118 INT98856 Negative_regulation of Gene_expression of Adrbk1 5 0.56 0.43 7.29
119 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27
120 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25
121 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
122 INT50779 Positive_regulation of Gene_expression of Adrbk1 9 0.56 2.79 7.23
123 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05
124 INT81880 Positive_regulation of Gene_expression of Sele 30 0.48 27.54 7.05
125 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92
126 INT22369 Negative_regulation of Drd1a 15 0.47 6.13 6.87
127 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
128 INT90097 Localization of PTGS2 15 0.69 6.14 6.63
129 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59
130 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52
131 INT107737 Positive_regulation of Pld2 11 0.67 0.33 6.45
132 INT134290 Positive_regulation of PLD2 10 0.68 3.06 6.44
133 INT83712 Transcription of Nos3 19 0.69 13.09 6.31
134 INT94197 Negative_regulation of Phosphorylation of MAPK3 13 0.57 5.51 6.18
135 INT67656 Positive_regulation of Positive_regulation of PTGS2 12 0.46 4.83 6.17
136 INT48926 Positive_regulation of Gene_expression of Mapk3 12 0.46 6.02 6.13
137 INT139964 Regulation of Phosphorylation of Mapk1 12 0.58 10.04 6.1
138 INT21552 Regulation of Drd1a 10 0.57 3.7 6.05
139 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
140 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9
141 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86
142 INT74109 Positive_regulation of Sele 26 0.48 22.32 5.84
143 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
144 INT82451 Negative_regulation of HMOX1 18 0.51 13.29 5.74
145 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71
146 INT1243 Regulation of ADRB2 16 0.54 1.84 5.66
147 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
148 INT18366 Negative_regulation of Positive_regulation of Drd1a 6 0.42 0.49 5.54
149 INT72000 Gene_expression of Gnaq 17 0.75 3.12 5.48
150 INT9325 Gene_expression of Igf1r 14 0.77 8.74 5.48
151 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47
152 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39
153 INT99487 Negative_regulation of MAPK3 15 0.57 7.13 5.39
154 INT100222 Binding of Src 9 0.26 5.41 5.37
155 INT62525 Positive_regulation of SELE 38 0.70 46 5.25
156 INT50105 Localization of CTSB 29 0.78 10.98 5.21
157 INT62832 Negative_regulation of Gene_expression of SELE 16 0.49 10.6 5.12
158 INT13885 Positive_regulation of Adrb2 9 0.49 1.11 5.12
159 INT13051 Regulation of Kcnma1 12 0.12 2.09 5.06
160 INT88019 Positive_regulation of Gene_expression of Faslg 16 0.67 11.31 5.05
161 INT62822 Positive_regulation of Gene_expression of SELE 22 0.66 28.04 4.97
162 INT114058 Negative_regulation of Gene_expression of Insr 13 0.31 9.23 4.97
163 INT101925 Binding of Drd1a 9 0.43 1.82 4.97
164 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
165 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
166 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87
167 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
168 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84
169 INT136754 Gene_expression of SCARB1 64 0.77 43.28 4.82
170 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
171 INT7170 Positive_regulation of Positive_regulation of Ctsb 1 0.40 0 4.76
172 INT90852 Gene_expression of F2r 26 0.78 5.5 4.66
173 INT98453 Positive_regulation of Src 19 0.47 7.84 4.62
174 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
175 INT63651 Gene_expression of Adcyap1r1 17 0.77 2.57 4.58
176 INT48567 Transcription of Drd1a 7 0.51 2.44 4.54
177 INT115805 Gene_expression of PLD2 7 0.76 12.49 4.51
178 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5
179 INT113078 Phosphorylation of Drd1a 4 0.30 0.77 4.45
180 INT24930 Binding of Adrb2 6 0.26 4.18 4.44
181 INT6967 Regulation of KCNMA1 28 0.61 3.37 4.3
182 INT13333 Regulation of Gene_expression of Drd1a 8 0.36 3.37 4.28
183 INT51084 Binding of Insr 13 0.30 4.25 4.23
184 INT64338 Negative_regulation of Hmox1 16 0.56 12.72 4.2
185 INT62526 Negative_regulation of SELE 17 0.51 15.24 4.19
186 INT63977 Positive_regulation of Sele 28 0.68 18.49 4.17
187 INT230796 Phosphorylation of Irs1 70 0.81 31.73 4.13
188 INT52616 Negative_regulation of Positive_regulation of PTGS2 13 0.43 4.95 4.13
189 INT83035 Binding of INSR 16 0.47 9.29 4.11
190 INT83991 Regulation of Nos3 25 0.44 9.89 4.06
191 INT133244 Regulation of Positive_regulation of Mapk1 11 0.43 3.52 4.03
192 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
193 INT102515 Binding of Nos3 19 0.45 9.41 4.01
194 INT112782 Localization of Mapk3 8 0.78 1.87 3.98
195 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
196 INT100741 Positive_regulation of ADRBK1 10 0.64 1.01 3.95
197 INT484 Negative_regulation of ADRB2 13 0.59 2.85 3.94
198 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
199 INT97096 Regulation of Hmox1 18 0.61 6.42 3.9
200 INT115773 Negative_regulation of Localization of Ptgs2 6 0.43 2.99 3.81
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