GO:0005905

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Name coated pit
Categary Component
Go Slim No
Go Link GO:0005905
Unique Molecular Interactions 442
Total Molecular Interactions 620
Total Single Events 6067
Pain Genes Associated 49

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for coated pit. They are ordered first by their pain relevance and then by number of times they were reported for coated pit. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
2 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64
3 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
4 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
5 INT305741 Binding of Kcnk2 and Sort1 1 0.54 1.01 1.8
6 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79
7 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
8 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
9 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
10 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
11 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
12 INT94367 Binding of ARRB1 and TP53INP2 1 0.25 0 1.3
13 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
14 INT301166 LRP2 Regulation of TRD@ 1 0.12 1.93 1.21
15 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
16 INT305734 Binding of Sort1 and Trpv1 1 0.01 0.5 1.08
17 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
18 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04
19 INT146098 Binding of Rgs9 and Arrb2 1 0.19 0 1.03
20 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1
21 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
22 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
23 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96
24 INT81329 Binding of ARRB1 and OPRK1 1 0.05 0.1 0.93
25 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
26 INT159993 App Regulation of Gene_expression of Bace1 1 0.46 0.32 0.92
27 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
28 INT305742 Binding of Sort1 and Gtf3a 1 0.01 0.64 0.88
29 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
30 INT77393 Binding of ARRB1 and OPRM1 1 0.15 0 0.82
31 INT139745 Positive_regulation of Binding of Oprm1 and Arrb2 1 0.28 0.14 0.81
32 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 0.01 1.2 0.79
33 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
34 INT346133 RAMP2 Regulation of ADM 1 0.13 2.06 0.78
35 INT66580 Binding of Ap1s1 and Rare2 1 0.00 0.07 0.76
36 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
37 INT44503 Cubn Positive_regulation of Prl 1 0.18 0 0.74
38 INT772 Tf Positive_regulation of Positive_regulation of Oprl1 1 0.11 0 0.7
39 INT778 Tf Positive_regulation of Gh1 1 0.14 0 0.7
40 INT782 Tf Positive_regulation of Prl 1 0.43 0 0.7
41 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
42 INT94366 Binding of ARRB1 and OPRD1 1 0.11 0 0.67
43 INT335054 LPL Positive_regulation of Localization of VLDLR 1 0.04 1.48 0.67
44 INT334128 Acsm3 Positive_regulation of Sele 1 0.16 1.6 0.66
45 INT176476 TNF Positive_regulation of Gene_expression of SELE 1 0.04 0.57 0.63
46 INT2700 Binding of App and Cpe 1 0.00 0 0.63
47 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
48 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
49 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
50 INT84771 Positive_regulation of Binding of App and Pag1 1 0.17 0.9 0.62
51 INT55919 Binding of Sigmar1 and Ap2s1 1 0.02 0.84 0.6
52 INT40901 Trf Regulation of Localization of POMC 1 0.07 0.56 0.6
53 INT120203 Binding of App and Il1 1 0.17 1.28 0.59
54 INT120204 Binding of App and Il1f5 1 0.09 1.28 0.59
55 INT84770 Binding of App and Pag1 1 0.13 0.89 0.57
56 INT39210 TF Positive_regulation of Gene_expression of IL2 1 0.17 0.07 0.57
57 INT27871 Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
58 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
59 INT334013 Ccl25 Positive_regulation of Gene_expression of Lrp1 1 0.07 0.98 0.56
60 INT77394 Binding of ARRB1 and GIPC1 1 0.01 0 0.56
61 INT167618 Rho Regulation of App 1 0.17 0.88 0.55
62 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55
63 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
64 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54
65 INT187101 Selp Regulation of Sele 1 0.20 1.23 0.53
66 INT334901 LDLR Positive_regulation of Crp 1 0.00 1.48 0.51
67 INT139834 NFKB1 Regulation of Gene_expression of SELE 1 0.18 0.49 0.5
68 INT139835 NFKB1 Regulation of SELE 1 0.41 0.49 0.5
69 INT324816 Hspd1 Positive_regulation of Gene_expression of Ik 1 0.00 1.59 0.5
70 INT146113 Binding of Adra2a and Lrp1 1 0.01 1.07 0.48
71 INT81330 ARRB1 Regulation of OPRK1 1 0.04 0.09 0.47
72 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
73 INT132445 TF Positive_regulation of IL8 1 0.11 2.23 0.46
74 INT69638 Binding of TF and Zfp354a 1 0.00 0 0.46
75 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
76 INT167621 Psenen Positive_regulation of App 1 0.02 0.86 0.44
77 INT84517 IRF6 Positive_regulation of TF 1 0.14 0.19 0.44
78 INT167617 Bace2 Positive_regulation of App 1 0.06 0.87 0.44
79 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 0.00 0.88 0.44
80 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43
81 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42
82 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
83 INT237896 Epn1 Regulation of Nps 1 0.06 0.19 0.41
84 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
85 INT84516 NFKB1 Positive_regulation of Gene_expression of TF 1 0.10 0.09 0.41
86 INT84518 IRF6 Positive_regulation of Gene_expression of TF 1 0.14 0.09 0.41
87 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
88 INT58480 Agpat1 Regulation of TF 1 0.00 0.46 0.4
89 INT58481 Crp Regulation of TF 1 0.01 0.46 0.4
90 INT38269 Binding of TCN1 and CUBN 1 0.00 0.28 0.4
91 INT79577 APP Negative_regulation of PENK 1 0.12 0.35 0.4
92 INT78121 Positive_regulation of Binding of App and 20S 1 0.23 0.61 0.4
93 INT78122 Binding of App and 20S 1 0.16 0.61 0.4
94 INT288700 Binding of Cp and Tfrc 1 0.40 0 0.39
95 INT323967 Il6 Positive_regulation of Gene_expression of App 1 0.10 0.86 0.38
96 INT262153 Binding of Clta and Nr1i2 1 0.05 0.65 0.38
97 INT116678 Binding of ARRB1 and Oxtr 1 0.13 0.15 0.38
98 INT300610 Rorb Regulation of Dnm2 1 0.01 0.27 0.37
99 INT297314 Binding of Bsg and Sele 1 0.11 1.37 0.37
100 INT84521 Binding of F7 and TF 1 0.06 0.09 0.37
101 INT143917 Binding of Src and Arrb2 1 0.27 0.07 0.37
102 INT78854 APP Positive_regulation of Localization of IL6 1 0.14 0.79 0.37
103 INT143914 Binding of Rbm39 and Arrb2 1 0.03 0.07 0.37
104 INT300608 Arc Regulation of Dnm2 1 0.15 0.27 0.37
105 INT316672 Binding of LRP1 and SFTPD 1 0.35 0.96 0.37
106 INT193492 Binding of Icam1 and Sele 1 0.06 1.05 0.34
107 INT182126 IRF6 Positive_regulation of Gene_expression of SELE 1 0.03 0.86 0.34
108 INT124376 Prodh2 Positive_regulation of App 1 0.00 0.66 0.33
109 INT124379 Prodh2 Positive_regulation of Localization of App 1 0.00 0.66 0.33
110 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32
111 INT61265 Nfkb1 Regulation of Gene_expression of Sele 1 0.28 0.65 0.32
112 INT147434 Psenen Positive_regulation of APP 1 0.01 0.58 0.32
113 INT324830 Hspd1 Positive_regulation of IFNA1 1 0.04 0.46 0.3
114 INT68977 App Positive_regulation of Localization of Mmp9 1 0.05 0.38 0.3
115 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
116 INT319220 FSIP1 Regulation of APP 1 0.29 1.46 0.29
117 INT262208 Clta Positive_regulation of Nr1i2 1 0.09 0.59 0.29
118 INT141871 Binding of Nos3 and Slc2a4 1 0.25 0.51 0.28
119 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
120 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
121 INT120975 Ins1 Positive_regulation of Gene_expression of Slc2a4 1 0.19 0.75 0.27
122 INT84523 TRAF3IP2 Regulation of Gene_expression of TF 1 0.05 0.1 0.27
123 INT84519 TRAF3IP2 Positive_regulation of Gene_expression of TF 1 0.05 0.1 0.27
124 INT79592 Binding of APP and Reg1 1 0.01 0.16 0.27
125 INT3577 Tf Negative_regulation of Positive_regulation of Gh1 1 0.49 0 0.27
126 INT25946 Regulation of Binding of Penk and App 1 0.18 0.19 0.27
127 INT45196 Cubn Negative_regulation of Prl 1 0.05 0 0.27
128 INT25944 Binding of Penk and App 1 0.15 0.19 0.27
129 INT356094 Binding of App and Tg 1 0.08 0.12 0.26
130 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26
131 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26
132 INT39010 App Negative_regulation of Gene_expression of Gnrh1 1 0.05 0.07 0.26
133 INT220635 Binding of Lrp1 and Kat5 2 0.09 0.71 0.25
134 INT114244 Cpox Negative_regulation of Gene_expression of APP 1 0.00 0.7 0.25
135 INT111909 Binding of HSPD1 and CCT4 1 0.29 0.48 0.25
136 INT111908 Binding of HSPD1 and AP4B1 1 0.03 0.48 0.25
137 INT198926 Binding of Apbb1 and Lrp1 5 0.12 2.18 0.24
138 INT78296 Negative_regulation of Binding of Ptpra and Ldlr 1 0.22 0.25 0.24
139 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
140 INT276952 Tlr2 Positive_regulation of Localization of Hspd1 1 0.25 0.16 0.24
141 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
142 INT78291 Binding of Ptpra and Ldlr 1 0.20 0.25 0.24
143 INT191619 Binding of App and Flna 1 0.04 0.18 0.24
144 INT224135 Binding of ARRB2 and Adora2b 1 0.14 0.07 0.23
145 INT132447 TF Positive_regulation of IL6 1 0.09 1.1 0.23
146 INT324835 Hspd1 Positive_regulation of Gene_expression of IFNA1 1 0.15 0.31 0.23
147 INT295329 ecs Positive_regulation of TF 1 0.00 1.2 0.23
148 INT70082 Binding of APP and TGM1 1 0.00 1.22 0.22
149 INT194404 Binding of RAMP2 and DCLK3 1 0.07 0 0.22
150 INT141623 OLR1 Positive_regulation of Gene_expression of TF 1 0.01 1.39 0.21
151 INT141625 Crp Positive_regulation of Gene_expression of TF 1 0.11 1.39 0.21
152 INT319971 App Regulation of Enpp1 1 0.02 0.72 0.21
153 INT151424 Tfrc Negative_regulation of Positive_regulation of Tnni3 1 0.21 0.98 0.2
154 INT55300 Slc2a1 Regulation of Gene_expression of Slc2a4 1 0.41 0.41 0.19
155 INT146687 Regulation of Binding of App and Aph1a 1 0.16 0.58 0.19
156 INT146686 Binding of App and Aph1a 1 0.14 0.58 0.19
157 INT55296 Slc2a4 Regulation of Ins1 1 0.17 0.41 0.19
158 INT82554 Sele Regulation of Il6 1 0.25 0.83 0.19
159 INT55299 Slc2a4 Regulation of Gene_expression of Slc2a1 1 0.41 0.41 0.19
160 INT231763 Binding of HSPD1 and TLR2 1 0.12 2 0.19
161 INT251492 Binding of HSPD1 and SOD1 1 0.02 1.45 0.18
162 INT276946 Hspd1 Positive_regulation of Tlr2 2 0.37 1.01 0.17
163 INT25945 Plat Regulation of App 1 0.15 0.25 0.17
164 INT132457 Binding of TF and Gtf3a 1 0.01 0.64 0.17
165 INT132446 Binding of TF and COBRA1 1 0.01 0.63 0.17
166 INT25947 Plat Regulation of Transcription of App 1 0.15 0.25 0.17
167 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
168 INT47965 Binding of TF and GORASP1 1 0.52 0.35 0.16
169 INT224136 ARRB2 Positive_regulation of Adora2b 1 0.19 0 0.16
170 INT319974 App Negative_regulation of Enpp1 1 0.02 0.58 0.16
171 INT231765 Binding of HSPD1 and TLR4 1 0.13 1.94 0.16
172 INT204478 Fmr1 Regulation of Gene_expression of App 1 0.50 1.44 0.16
173 INT47964 Binding of REL and TF 1 0.52 0.35 0.16
174 INT201744 Ngf Regulation of Transcription of App 1 0.06 0.39 0.15
175 INT201728 Ntrk1 Regulation of Transcription of App 1 0.03 0.39 0.15
176 INT224132 ARRB2 Negative_regulation of Positive_regulation of Adora2b 1 0.14 0.28 0.15
177 INT63981 Sele Regulation of Positive_regulation of Icam1 1 0.17 0.71 0.15
178 INT131304 Binding of Serping1 and Sele 1 0.01 1.07 0.15
179 INT319972 App Negative_regulation of Gene_expression of Enpp1 1 0.02 1.87 0.15
180 INT63980 Icam1 Regulation of Positive_regulation of Sele 1 0.17 0.71 0.15
181 INT286476 Binding of App and Itm2b 1 0.47 5.24 0.14
182 INT94763 PSEN2 Regulation of Positive_regulation of App 1 0.11 0.72 0.14
183 INT139849 Binding of App and Bace1 7 0.41 0.85 0.13
184 INT204489 Fmr1 Regulation of App 1 0.50 1.71 0.13
185 INT324804 Binding of Hspd1 and Tlr4 1 0.14 0.36 0.13
186 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13
187 INT310412 Binding of CP and TF 1 0.14 1.66 0.13
188 INT276950 Hspd1 Positive_regulation of Positive_regulation of Tlr2 1 0.22 1.25 0.13
189 INT220622 App Positive_regulation of Rip 2 0.14 0.24 0.12
190 INT270723 Negative_regulation of HMGCR Positive_regulation of LDLR 1 0.02 0.52 0.12
191 INT21620 Binding of Ttpa and Vldlr 1 0.22 0.27 0.12
192 INT308660 Binding of Ager and App 1 0.08 1.22 0.12
193 INT149792 Binding of Reln and Vldlr 3 0.51 0.35 0.11
194 INT70084 Negative_regulation of Binding of APP and TGM1 1 0.00 0.61 0.11
195 INT70083 TGM1 Positive_regulation of Binding of APP 1 0.00 0.61 0.11
196 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11
197 INT99140 LDLR Positive_regulation of Localization of VCAM1 1 0.05 0.44 0.11
198 INT269783 Crp Positive_regulation of Sele 1 0.00 1.69 0.11
199 INT126922 Ins1 Positive_regulation of Localization of Slc2a4 1 0.23 0.75 0.11
200 INT210899 Binding of SELE and IGHD1-14 1 0.39 3.31 0.11

Single Events

The table below shows the top 100 pain related interactions that have been reported for coated pit. They are ordered first by their pain relevance and then by number of times they were reported in coated pit. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65500 Gene_expression of App 605 0.78 429.94 98.31
2 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
3 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
4 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
5 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
6 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92
7 INT11625 Localization of App 98 0.78 55.46 20.86
8 INT16794 Binding of App 103 0.48 64.87 19.79
9 INT65502 Regulation of App 77 0.62 52.05 19.44
10 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41
11 INT61257 Gene_expression of Sele 79 0.77 70.97 17.78
12 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
13 INT54052 Gene_expression of App 33 0.78 25.08 14.7
14 INT29745 Binding of APP 47 0.48 26.49 12.4
15 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38
16 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75
17 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48
18 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15
19 INT13240 Gene_expression of TF 94 0.76 57.81 10.99
20 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38
21 INT48131 Gene_expression of Slc2a4 32 0.78 14.64 10.16
22 INT41569 Regulation of APP 32 0.62 17.15 9.4
23 INT8249 Positive_regulation of Cubn 15 0.66 4.05 9.35
24 INT13893 Negative_regulation of Cubn 9 0.36 1.78 9.24
25 INT15805 Gene_expression of TFRC 35 0.75 17.44 8.52
26 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87
27 INT99430 Positive_regulation of Gene_expression of Slc2a4 18 0.66 10.45 7.79
28 INT56031 Positive_regulation of App 25 0.69 13.46 7.37
29 INT77404 Gene_expression of ARRB1 19 0.62 1.53 7.22
30 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
31 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05
32 INT81880 Positive_regulation of Gene_expression of Sele 30 0.48 27.54 7.05
33 INT100079 Positive_regulation of Gene_expression of Arrb2 7 0.63 2.26 6.77
34 INT77408 Binding of ARRB1 11 0.36 0.31 6.51
35 INT94979 Regulation of Arrb2 6 0.54 0.51 6.45
36 INT80447 Negative_regulation of ARRB2 5 0.39 3.12 6.3
37 INT94986 Positive_regulation of Arrb2 5 0.61 1.3 6.24
38 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
39 INT74109 Positive_regulation of Sele 26 0.48 22.32 5.84
40 INT102836 Binding of LRP2 12 0.38 11.27 5.58
41 INT107173 Phosphorylation of App 20 0.82 12.64 5.3
42 INT62525 Positive_regulation of SELE 38 0.70 46 5.25
43 INT22597 Positive_regulation of TF 43 0.68 27.27 5.17
44 INT85685 Gene_expression of Arrb2 5 0.74 0.66 5.13
45 INT62832 Negative_regulation of Gene_expression of SELE 16 0.49 10.6 5.12
46 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
47 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
48 INT62822 Positive_regulation of Gene_expression of SELE 22 0.66 28.04 4.97
49 INT201653 Gene_expression of Sort1 6 0.75 6.29 4.89
50 INT131692 Negative_regulation of Localization of App 9 0.53 4.69 4.82
51 INT85681 Negative_regulation of Arrb2 5 0.47 0.79 4.71
52 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56
53 INT78116 Positive_regulation of Gene_expression of App 12 0.70 10.78 4.52
54 INT108935 Transcription of Arrb2 5 0.59 0.5 4.38
55 INT11565 Gene_expression of Tf 24 0.68 5.89 4.36
56 INT148901 Binding of Sort1 2 0.39 3.65 4.32
57 INT92797 Regulation of Arrb2 4 0.44 0.81 4.28
58 INT58003 Localization of APP 32 0.80 13.75 4.2
59 INT94985 Regulation of Gene_expression of Arrb2 2 0.40 0.43 4.2
60 INT62526 Negative_regulation of SELE 17 0.51 15.24 4.19
61 INT63977 Positive_regulation of Sele 28 0.68 18.49 4.17
62 INT173910 Gene_expression of LRP2 24 0.75 19.99 4.09
63 INT99821 Negative_regulation of Gene_expression of APP 20 0.42 15.21 3.94
64 INT85679 Binding of Arrb2 4 0.39 0.79 3.82
65 INT102452 Gene_expression of RAMP2 6 0.69 7.11 3.77
66 INT129746 Positive_regulation of Gene_expression of Tfrc 4 0.18 2.15 3.74
67 INT18822 Regulation of Cubn 4 0.27 0.17 3.74
68 INT73981 Gene_expression of Hspd1 18 0.75 5.69 3.72
69 INT63979 Regulation of Sele 13 0.54 10.64 3.7
70 INT11627 Positive_regulation of Localization of App 14 0.62 6.27 3.64
71 INT99819 Negative_regulation of Positive_regulation of APP 6 0.58 4.41 3.64
72 INT61253 Negative_regulation of Sele 13 0.57 11.68 3.56
73 INT94983 Negative_regulation of Arrb2 2 0.52 0.26 3.47
74 INT57728 Regulation of LDLR 25 0.41 13.18 3.46
75 INT148899 Regulation of Sort1 2 0.50 2.72 3.46
76 INT70089 Negative_regulation of Binding of APP 7 0.59 6.45 3.44
77 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32
78 INT5166 Binding of Ldlr 14 0.48 11.95 3.32
79 INT15801 Positive_regulation of TFRC 11 0.33 6.35 3.3
80 INT68846 Gene_expression of Tfrc 22 0.32 10.1 3.06
81 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05
82 INT85682 Positive_regulation of Arrb2 4 0.46 0.22 3.05
83 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04
84 INT108773 Negative_regulation of Binding of App 10 0.42 7.26 2.96
85 INT54055 Regulation of Gene_expression of App 7 0.62 4.04 2.93
86 INT46650 Localization of Trf 13 0.61 4.4 2.91
87 INT51460 Negative_regulation of Gene_expression of Sele 8 0.52 10.18 2.89
88 INT178772 Transcription of App 17 0.70 10.79 2.79
89 INT147429 Negative_regulation of Positive_regulation of App 8 0.40 8.73 2.78
90 INT54054 Binding of App 4 0.48 10.89 2.78
91 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73
92 INT80880 Gene_expression of ARRB2 4 0.65 3.51 2.71
93 INT106833 Positive_regulation of ARRB1 4 0.39 1.21 2.71
94 INT81411 Negative_regulation of Sele 8 0.38 7 2.7
95 INT17033 Positive_regulation of Trf 21 0.62 11.76 2.68
96 INT100360 Negative_regulation of TF 19 0.42 10.43 2.68
97 INT115250 Positive_regulation of Slc2a4 16 0.67 8.13 2.64
98 INT51753 Negative_regulation of Tfrc 7 0.41 3.47 2.62
99 INT48130 Transcription of Slc2a4 9 0.69 5.58 2.46
100 INT237875 Gene_expression of Epn1 1 0.10 1.26 2.4
101 INT73671 Regulation of Gene_expression of Sele 8 0.45 7.01 2.39
102 INT21726 Gene_expression of Tfrc 10 0.74 7.38 2.36
103 INT162513 Regulation of Protein_catabolism of APP 5 0.51 1.79 2.36
104 INT11626 Regulation of Localization of App 4 0.45 1.51 2.34
105 INT56030 Regulation of App 8 0.62 4.06 2.32
106 INT108937 Negative_regulation of Transcription of Arrb2 1 0.38 0.31 2.31
107 INT27880 Positive_regulation of HSPD1 17 0.65 18.16 2.23
108 INT77396 Regulation of ARRB1 6 0.35 2.04 2.22
109 INT195191 Gene_expression of Cubn 2 0.06 0 2.17
110 INT152436 Positive_regulation of Gene_expression of HSPD1 12 0.67 10.06 2.16
111 INT66881 Positive_regulation of Sort1 2 0.57 0.99 2.16
112 INT108939 Regulation of Transcription of Arrb2 1 0.24 0.19 2.1
113 INT124772 Regulation of Binding of App 6 0.45 4.92 2.09
114 INT39008 Localization of App 13 0.77 9.07 2.05
115 INT82543 Negative_regulation of Gene_expression of TFRC 4 0.57 1.27 2.03
116 INT83332 Regulation of Gene_expression of TFRC 5 0.22 3.03 1.99
117 INT77410 Positive_regulation of Gene_expression of ARRB1 3 0.55 0.21 1.98
118 INT262364 Positive_regulation of LRP2 6 0.39 4.44 1.97
119 INT66882 Gene_expression of Sort1 3 0.73 0.64 1.97
120 INT83329 Regulation of Gene_expression of Tf 4 0.16 1.83 1.93
121 INT142774 Regulation of Phosphorylation of App 1 0.59 2.27 1.93
122 INT198885 Gene_expression of Lrp1 33 0.57 10.2 1.91
123 INT237873 Regulation of Epn1 1 0.07 2.12 1.91
124 INT41633 Positive_regulation of Positive_regulation of Cubn 2 0.48 0.1 1.89
125 INT36499 Negative_regulation of Tf 6 0.38 3.02 1.85
126 INT80885 Positive_regulation of Gene_expression of ARRB2 3 0.49 1.36 1.82
127 INT121117 Regulation of Protein_catabolism of App 10 0.62 6.41 1.78
128 INT27881 Binding of HSPD1 10 0.31 9.2 1.78
129 INT107915 Regulation of Negative_regulation of App 6 0.45 4.47 1.76
130 INT115256 Localization of Slc2a4 13 0.77 8.06 1.72
131 INT113539 Positive_regulation of Binding of ARRB1 1 0.02 0.11 1.72
132 INT125844 Positive_regulation of Gene_expression of Arrb2 2 0.48 0.45 1.66
133 INT48126 Negative_regulation of Gene_expression of Slc2a4 5 0.59 1.79 1.63
134 INT61256 Negative_regulation of Transcription of Sele 2 0.43 1.24 1.6
135 INT48128 Regulation of Gene_expression of Slc2a4 5 0.62 1.25 1.59
136 INT61261 Transcription of Sele 2 0.53 1.24 1.58
137 INT133863 Positive_regulation of Protein_catabolism of App 12 0.59 7.53 1.52
138 INT58004 Positive_regulation of Localization of APP 5 0.46 2.1 1.5
139 INT230805 Localization of Slc2a4 23 0.46 11 1.48
140 INT59795 Regulation of Tfrc 5 0.43 4.43 1.48
141 INT158184 Localization of ARRB2 2 0.52 1.3 1.47
142 INT25943 Transcription of App 5 0.53 1.79 1.44
143 INT54593 Positive_regulation of Gene_expression of TF 16 0.68 9.05 1.43
144 INT15798 Positive_regulation of Gene_expression of TFRC 9 0.46 4.99 1.42
145 INT125796 Regulation of Gene_expression of APP 8 0.59 5.95 1.41
146 INT129700 Regulation of Positive_regulation of App 3 0.43 1.86 1.41
147 INT108936 Positive_regulation of Positive_regulation of Arrb2 1 0.41 0.25 1.4
148 INT53775 Gene_expression of Hspd1 21 0.78 31.25 1.38
149 INT10829 Regulation of Ldlr 12 0.34 8.12 1.35
150 INT16239 Negative_regulation of Trf 9 0.32 4.06 1.35
151 INT141529 Regulation of Positive_regulation of APP 3 0.44 0.31 1.34
152 INT158183 Positive_regulation of Negative_regulation of ARRB2 1 0.35 1.13 1.33
153 INT61263 Negative_regulation of Gene_expression of Sele 6 0.43 5.65 1.31
154 INT77398 Negative_regulation of ARRB1 1 0.47 0 1.31
155 INT305718 Localization of Sort1 1 0.73 0.83 1.3
156 INT36500 Negative_regulation of Gene_expression of Tf 4 0.38 1.22 1.29
157 INT103488 Positive_regulation of Localization of App 5 0.50 3.05 1.28
158 INT106830 Positive_regulation of Positive_regulation of ARRB1 1 0.16 0.13 1.28
159 INT55916 Binding of Ap2s1 4 0.14 6.56 1.27
160 INT63978 Regulation of Gene_expression of Sele 5 0.18 4.59 1.24
161 INT53776 Positive_regulation of Hspd1 17 0.70 10.64 1.23
162 INT132453 Binding of TF 31 0.36 12.98 1.22
163 INT73176 Positive_regulation of Hspd1 5 0.35 3.96 1.22
164 INT257952 Positive_regulation of CUBN 1 0.07 0.61 1.22
165 INT48129 Negative_regulation of Slc2a4 7 0.59 3.19 1.21
166 INT106832 Localization of ARRB1 2 0.22 0.3 1.21
167 INT6996 Positive_regulation of Tfrc 6 0.70 2.22 1.2
168 INT44498 Localization of Cubn 2 0.34 0.38 1.19
169 INT116537 Binding of ARRB2 1 0.34 0.3 1.19
170 INT302068 Phosphorylation of Arrb2 1 0.01 0.27 1.19
171 INT36443 Regulation of Trf 4 0.61 1.65 1.18
172 INT769 Regulation of Tf 3 0.30 1 1.18
173 INT112891 Regulation of Gene_expression of HSPD1 2 0.43 3.98 1.17
174 INT23199 Binding of LDLR 22 0.47 17.08 1.16
175 INT100137 Positive_regulation of Negative_regulation of App 2 0.41 1.26 1.16
176 INT72864 Positive_regulation of Gene_expression of Sele 9 0.68 7.46 1.14
177 INT173916 Regulation of LRP2 6 0.44 7.96 1.14
178 INT135899 Regulation of Binding of APP 3 0.45 1.22 1.14
179 INT82703 Transcription of LDLR 6 0.64 0.4 1.13
180 INT77411 Regulation of Gene_expression of ARRB1 3 0.36 0.61 1.12
181 INT41333 Negative_regulation of Positive_regulation of Cubn 2 0.15 0.47 1.12
182 INT55294 Gene_expression of Slc2a4 17 0.70 6.84 1.11
183 INT198879 Localization of Vldlr 6 0.39 0.58 1.1
184 INT305721 Binding of Sort1 1 0.47 0.92 1.1
185 INT83465 Positive_regulation of Localization of Sele 1 0.09 2.81 1.08
186 INT83463 Localization of Sele 1 0.14 2.81 1.08
187 INT39009 Negative_regulation of App 6 0.38 3.37 1.07
188 INT82540 Negative_regulation of TFRC 3 0.41 0.77 1.07
189 INT106835 Positive_regulation of Localization of ARRB1 1 0.15 0.11 1.04
190 INT198904 Localization of Lrp1 11 0.62 3.25 1.01
191 INT184479 Regulation of Tfrc 3 0.09 3.97 1.01
192 INT148900 Localization of Sort1 1 0.44 0.5 1.01
193 INT3568 Localization of Tf 4 0.62 1.27 1
194 INT215363 Regulation of HSPD1 4 0.51 2.74 0.99
195 INT82707 Positive_regulation of Transcription of LDLR 1 0.62 0.34 0.98
196 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97
197 INT108943 Positive_regulation of Negative_regulation of Arrb2 1 0.61 0.06 0.97
198 INT272918 Positive_regulation of Positive_regulation of SELE 2 0.03 2.24 0.96
199 INT82702 Positive_regulation of Positive_regulation of LDLR 4 0.45 1.08 0.95
200 INT115471 Binding of Sele 5 0.36 4.06 0.94
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