GO:0005911

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Name cell-cell junction
Categary Component
Go Slim No
Go Link GO:0005911
Unique Molecular Interactions 586
Total Molecular Interactions 859
Total Single Events 6052
Pain Genes Associated 97

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell-cell junction. They are ordered first by their pain relevance and then by number of times they were reported for cell-cell junction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125407 Binding of OPRL1 and PTPRM 1 0.03 0.72 4.67
2 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
3 INT87267 Binding of BMP8B and KRIT1 1 0.06 0.16 2.69
4 INT284860 Binding of Pdzd2 and Nav1 9 0.29 2.33 2.34
5 INT134742 Binding of OPRM1 and SV2A 1 0.33 0.18 1.64
6 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
7 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56
8 INT87266 Negative_regulation of Binding of BMP8B and KRIT1 1 0.05 0.07 1.37
9 INT122144 Binding of Trpv1 and Prkd1 1 0.02 0.39 0.96
10 INT167767 Prkcz Positive_regulation of Phosphorylation of Sigmar1 1 0.04 0.23 0.9
11 INT167766 Prkcz Positive_regulation of Positive_regulation of Sigmar1 1 0.04 0.23 0.9
12 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
13 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
14 INT155761 Binding of Nos1 and Tjp1 1 0.13 1.01 0.82
15 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
16 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
17 INT167770 Sigmar1 Positive_regulation of Prkcz 1 0.04 0.34 0.77
18 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
19 INT167768 Regulation of Sigmar1 Positive_regulation of Prkcz 1 0.02 0.34 0.77
20 INT332538 Binding of AD5 and Cxadr 1 0.08 0.98 0.76
21 INT23681 Negative_regulation of Binding of Stx3 and Chrna7 1 0.00 0 0.75
22 INT23680 Binding of Stx3 and Chrna7 1 0.00 0 0.75
23 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
24 INT120819 Binding of ASIC3 and Lin7b 1 0.01 0 0.73
25 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
26 INT337157 Iqgap1 Regulation of Gene_expression of Ros1 1 0.07 1.91 0.72
27 INT87275 KRIT1 Regulation of Oprd1 1 0.01 0.08 0.72
28 INT120818 Lin7b Positive_regulation of ASIC3 1 0.01 0 0.71
29 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
30 INT12238 CCK Positive_regulation of CDH2 1 0.02 0 0.7
31 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
32 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
33 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
34 INT74729 Binding of Mpz and Ptprj 1 0.06 0.15 0.66
35 INT2401 SCT Positive_regulation of SGCA 1 0.00 0 0.62
36 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
37 INT138886 Binding of F11r and Tjp1 1 0.13 0.86 0.6
38 INT346412 Binding of Tesc and Sv2a 1 0.02 0.6 0.59
39 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
40 INT177269 Binding of CXADR and NR1H4 1 0.04 0 0.58
41 INT118001 Csk Regulation of Trpv1 1 0.08 0.09 0.58
42 INT23679 Chrna7 Regulation of Binding of Stx3 1 0.00 0 0.56
43 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
44 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
45 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
46 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
47 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
48 INT144130 Binding of Gja1 and Prkcg 1 0.48 0.5 0.52
49 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
50 INT120384 PRKCD Positive_regulation of Localization of HSPG2 1 0.29 0.42 0.51
51 INT66188 Binding of ADRB2 and CDSN 1 0.01 0 0.51
52 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
53 INT120382 PRKCD Positive_regulation of Localization of DYT10 1 0.29 0.42 0.51
54 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5
55 INT122107 Plbd2 Negative_regulation of Cdh2 1 0.03 0.42 0.5
56 INT161166 Binding of Aqp4 and Igh-6 1 0.03 2.58 0.49
57 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48
58 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
59 INT220188 EC Positive_regulation of CADM1 1 0.00 1.72 0.44
60 INT332539 Regulation of Binding of AD5 and Cxadr 1 0.09 0.65 0.44
61 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43
62 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
63 INT338044 F2 Positive_regulation of Pard3 1 0.08 0.38 0.4
64 INT264209 Binding of Igh-Lev and Sv2a 1 0.17 1.78 0.38
65 INT118002 Binding of Trpv1 and Csk 1 0.06 0.08 0.38
66 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
67 INT245343 Prkd1 Regulation of Slc3a1 1 0.29 0.47 0.36
68 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
69 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
70 INT342687 Pdzd2 Regulation of Gene_expression of Nav1 1 0.19 0.3 0.35
71 INT120817 Binding of Dlg4 and Lin7b 1 0.00 0 0.34
72 INT342691 Pdzd2 Regulation of Nav1 1 0.19 0.48 0.34
73 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
74 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
75 INT88252 Binding of RAP1A and Krit1 1 0.36 2.25 0.33
76 INT181896 TNF Regulation of TEK 1 0.03 1.21 0.33
77 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
78 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
79 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
80 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
81 INT259132 KLK7 Positive_regulation of Binding of DSG2 1 0.51 0.91 0.31
82 INT259130 KLK7 Positive_regulation of Binding of DSG1 1 0.51 0.91 0.31
83 INT259133 KLK7 Positive_regulation of DSG2 1 0.51 0.91 0.31
84 INT259131 KLK7 Positive_regulation of DSG1 1 0.51 0.91 0.31
85 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3
86 INT130128 Binding of Ocln and Tjp1 2 0.38 0.98 0.29
87 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
88 INT309063 Binding of Trpc3 and Trpc4 1 0.11 0.23 0.28
89 INT309056 Binding of Trpc4 and Trpc6 1 0.15 0.23 0.28
90 INT174311 Binding of Krit1 and Rap1a 1 0.04 1.08 0.28
91 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
92 INT337162 Binding of Kdr and Iqgap1 1 0.32 0.98 0.28
93 INT337161 Binding of Diap1 and Iqgap1 1 0.29 0.78 0.28
94 INT166094 Negative_regulation of CSK Negative_regulation of Positive_regulation of EGFR 1 0.02 0.33 0.28
95 INT238632 Binding of EPB41 and Cask 1 0.44 0.78 0.27
96 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26
97 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26
98 INT198648 VCAM1 Positive_regulation of CADM1 1 0.00 1.1 0.25
99 INT348755 Plat Regulation of Gene_expression of Cldn5 1 0.10 0.45 0.25
100 INT259937 Binding of CSK and PTPN22 1 0.21 1.69 0.25
101 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25
102 INT198644 TNF Positive_regulation of CADM1 1 0.02 1.07 0.24
103 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24
104 INT198643 CD36 Positive_regulation of CADM1 1 0.01 1.07 0.24
105 INT122145 Prkd1 Positive_regulation of Phosphorylation of Trpv1 1 0.02 0.09 0.23
106 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
107 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22
108 INT303029 Binding of TEK and Angpt1 1 0.26 1.82 0.22
109 INT337158 Binding of Iqgap1 and Wasl 1 0.09 0.55 0.22
110 INT190045 Binding of Ebp and Scrib 1 0.10 0.79 0.22
111 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21
112 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
113 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21
114 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2
115 INT352518 Binding of FAT1 and Adipoq 1 0.01 2.79 0.2
116 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
117 INT55300 Slc2a1 Regulation of Gene_expression of Slc2a4 1 0.41 0.41 0.19
118 INT217528 Binding of Tjp1 and Vapb 1 0.00 1.6 0.19
119 INT23585 Binding of KRIT1 and CCR1 1 0.40 0.97 0.19
120 INT55295 Slc2a1 Regulation of Ins1 1 0.17 0.41 0.19
121 INT23586 Binding of CALCR and KRIT1 1 0.40 0.97 0.19
122 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19
123 INT55299 Slc2a4 Regulation of Gene_expression of Slc2a1 1 0.41 0.41 0.19
124 INT287145 Binding of PNN and Shbg 1 0.07 0.14 0.18
125 INT337154 Binding of Iqgap1 and Braf 1 0.13 0.64 0.18
126 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
127 INT289630 Binding of CDSN and RS1 1 0.02 1.1 0.17
128 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16
129 INT141760 Nfkb1 Regulation of CADM1 1 0.02 1.18 0.16
130 INT259135 Gene_expression of KLK7 Positive_regulation of DSG2 1 0.47 1.21 0.16
131 INT141761 Nfkb1 Regulation of Positive_regulation of CADM1 1 0.01 1.21 0.16
132 INT284858 Binding of Gabbr1 and Pdzd2 1 0.03 0.24 0.15
133 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15
134 INT138305 Binding of PNN and Agtr2 1 0.01 0.73 0.15
135 INT316482 Il6 Positive_regulation of Cdh1 1 0.03 0.33 0.15
136 INT284856 Regulation of Binding of Gabbr1 and Pdzd2 1 0.04 0.24 0.15
137 INT106994 PARD3 Positive_regulation of PAR4 1 0.21 0.28 0.14
138 INT337164 Binding of DIAPH1 and Iqgap1 1 0.53 0.37 0.14
139 INT327879 Binding of Itgb1 and Postn 1 0.02 1.05 0.14
140 INT148800 VEGFA Positive_regulation of Positive_regulation of Csk 1 0.06 0 0.14
141 INT345171 Binding of Trip6 and Magi3 1 0.03 1.65 0.14
142 INT148802 Negative_regulation of VEGFA Positive_regulation of Csk 1 0.05 0 0.14
143 INT148801 VEGFA Positive_regulation of Csk 1 0.06 0 0.14
144 INT107006 PARD3 Positive_regulation of SPG21 1 0.24 0.29 0.14
145 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14
146 INT332540 Cxadr Regulation of Gene_expression of AD5 1 0.09 0.25 0.14
147 INT148330 Binding of Prkd1 and Trpv1 1 0.03 0.47 0.13
148 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
149 INT148328 Prkd1 Positive_regulation of Trpv1 1 0.31 0.39 0.13
150 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
151 INT327877 Itgb1 Negative_regulation of Gene_expression of Dlk1 1 0.02 0.99 0.13
152 INT106997 PARD3 Positive_regulation of NR1I2 1 0.19 0.28 0.13
153 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
154 INT337676 Binding of TIMP1 and Scrib 1 0.01 1.24 0.13
155 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13
156 INT208207 Binding of Cadm1 and Pvrl3 1 0.12 1.06 0.12
157 INT253328 Binding of IL8 and Scrib 1 0.04 0.79 0.12
158 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 0.14 0.18 0.12
159 INT340421 Il1a Positive_regulation of Csk 1 0.00 0.98 0.12
160 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
161 INT284854 Pdzd2 Positive_regulation of Gene_expression of Nav1 1 0.42 0 0.11
162 INT281301 Stx2 Positive_regulation of Localization of F3 1 0.10 0.19 0.11
163 INT74504 Binding of P2rx7 and Rp2 1 0.02 0.19 0.11
164 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
165 INT257467 Fat1 Regulation of Gene_expression of Adipoq 1 0.08 0.56 0.11
166 INT338041 F2r Positive_regulation of Pard3 1 0.15 0.05 0.11
167 INT338048 F2rl3 Positive_regulation of Pard3 1 0.11 0.05 0.11
168 INT271525 ITGB1 Positive_regulation of Gopc 1 0.02 0.57 0.11
169 INT352500 Binding of FAT1 and INS 1 0.01 1.38 0.1
170 INT111134 Binding of Krit1 and Rap1a 1 0.07 0.81 0.1
171 INT217530 Binding of Tjp1 and Tjp2 1 0.10 0.91 0.1
172 INT342694 Binding of Pdzd2 and Gopc 1 0.03 0.15 0.1
173 INT334865 Binding of Cadm3 and Cadm4 1 0.00 0.42 0.1
174 INT265346 Binding of Ocln and Tjp1 7 0.05 1.11 0.09
175 INT259129 KLK7 Regulation of DSG2 1 0.24 0.61 0.09
176 INT342690 Binding of Sft2d3 and Pdzd2 1 0.00 0.15 0.09
177 INT355584 VEGFA Positive_regulation of Positive_regulation of CDH5 1 0.06 1.35 0.09
178 INT260944 Mapk14 Positive_regulation of Transcription of Aqp3 1 0.29 0.21 0.09
179 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09
180 INT337165 Iqgap1 Positive_regulation of Gene_expression of VEGFA 1 0.03 0.27 0.09
181 INT142002 Trav9n-1 Negative_regulation of CDC42BPA 1 0.00 0 0.09
182 INT284853 Binding of S100a10 and Pdzd2 1 0.21 0.08 0.09
183 INT260947 Mapk14 Positive_regulation of Aqp3 1 0.29 0.21 0.09
184 INT252421 Gja1 Regulation of P2ry1 1 0.00 0.28 0.09
185 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 0.02 0 0.09
186 INT270824 Binding of P2rx7 and Panx1 1 0.34 0.15 0.09
187 INT177296 Binding of CXADR and CYP3A4 1 0.30 0 0.09
188 INT281312 Stx2 Positive_regulation of Gene_expression of F3 1 0.10 0.15 0.09
189 INT180443 Rhoa Regulation of Negative_regulation of Mlc1 1 0.04 0 0.09
190 INT257665 Binding of Nphs1 and Pard3 1 0.39 0.67 0.09
191 INT260945 Mapk14 Positive_regulation of Gene_expression of Aqp3 1 0.29 0.21 0.09
192 INT20959 Binding of PTPRC and Pak1 1 0.01 0.76 0.09
193 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09
194 INT141257 Binding of S100A8 and VCL 1 0.36 0.97 0.09
195 INT322851 Binding of KRIT1 and OSM 1 0.04 1.42 0.09
196 INT262335 Binding of Sv2a and Bri3 1 0.01 0.71 0.08
197 INT325295 Binding of SGCA and C14orf166 1 0.04 0.54 0.08
198 INT107885 Negative_regulation of TRPC6 Negative_regulation of Trpc4 1 0.01 0 0.08
199 INT353070 ADAM17 Positive_regulation of TNF 1 0.19 1.66 0.08
200 INT20957 Binding of Pak1 and Pak2 1 0.27 0.65 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell-cell junction. They are ordered first by their pain relevance and then by number of times they were reported in cell-cell junction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
2 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63
3 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
4 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72
5 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
6 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
7 INT36715 Gene_expression of Trpc4 50 0.68 4.18 11.13
8 INT109651 Negative_regulation of Aqp4 23 0.53 8.5 10.7
9 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
10 INT63701 Localization of KRIT1 11 0.78 2.02 9.17
11 INT22481 Gene_expression of CADM1 28 0.65 30.26 8.5
12 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
13 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4
14 INT83952 Gene_expression of Cxadr 24 0.75 22.38 6.77
15 INT87775 Phosphorylation of Gja1 13 0.82 2.75 6.56
16 INT130875 Gene_expression of ADAM17 13 0.78 15.46 6.41
17 INT118151 Positive_regulation of Prkcz 5 0.12 2.35 6.41
18 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
19 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
20 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
21 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56
22 INT155348 Positive_regulation of Aqp4 14 0.63 9.92 5.53
23 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
24 INT105284 Gene_expression of Ocln 39 0.78 14.98 5.08
25 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
26 INT105289 Gene_expression of Tjp1 28 0.76 11.72 4.67
27 INT119203 Gene_expression of CXADR 64 0.74 11.37 4.41
28 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
29 INT143337 Binding of Aqp4 30 0.40 23.73 4.24
30 INT87780 Gene_expression of Gja1 22 0.77 5.84 4.24
31 INT160023 Regulation of Aqp4 9 0.45 8.41 4.19
32 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
33 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79
34 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77
35 INT225965 Localization of Aqp4 26 0.81 18.85 3.75
36 INT130836 Transcription of Aqp4 6 0.72 5.93 3.52
37 INT134747 Gene_expression of SV2A 10 0.72 0.44 3.48
38 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
39 INT130835 Positive_regulation of Transcription of Aqp4 3 0.68 4.5 3.28
40 INT284848 Gene_expression of Pdzd2 23 0.74 1.36 3.25
41 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22
42 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
43 INT276520 Gene_expression of Iqgap1 2 0.76 8.67 3.1
44 INT155349 Positive_regulation of Gene_expression of Aqp4 8 0.70 6.26 2.94
45 INT152961 Negative_regulation of Gene_expression of Aqp4 13 0.59 10.01 2.92
46 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
47 INT118156 Binding of Prkcz 2 0.08 2.68 2.89
48 INT102157 Gene_expression of Adam17 3 0.58 4.17 2.86
49 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81
50 INT169323 Positive_regulation of Gene_expression of Cxadr 4 0.67 4.09 2.77
51 INT103020 Gene_expression of SGCA 22 0.56 14.29 2.75
52 INT145328 Negative_regulation of Scrib 25 0.16 26.79 2.66
53 INT125905 Gene_expression of Cldn5 7 0.57 4.33 2.66
54 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
55 INT104563 Localization of Aqp4 10 0.73 7.82 2.54
56 INT129695 Binding of Sv2a 6 0.47 4.96 2.51
57 INT2405 Negative_regulation of SGCA 15 0.57 6.04 2.45
58 INT183668 Binding of SGCA 15 0.36 9.86 2.42
59 INT225966 Regulation of Gene_expression of Aqp4 18 0.62 20.39 2.3
60 INT156373 Binding of Sv2a 4 0.39 1.54 2.3
61 INT177328 Positive_regulation of CXADR 9 0.48 4.29 2.27
62 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19
63 INT55291 Gene_expression of Slc2a1 20 0.68 11.46 2.16
64 INT125902 Positive_regulation of Gene_expression of Cldn5 5 0.51 3.13 2.16
65 INT49433 Binding of PTPRM 2 0.02 0.26 2.15
66 INT87778 Positive_regulation of Gene_expression of Gja1 6 0.69 1.46 2.14
67 INT14010 Gene_expression of SLC2A1 19 0.78 15.22 2.12
68 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
69 INT169705 Negative_regulation of Gene_expression of Cdh1 10 0.57 8.8 2.1
70 INT236959 Localization of PDZD2 7 0.16 5.77 2.1
71 INT149031 Gene_expression of Tjp1 43 0.75 19.1 2.06
72 INT155344 Phosphorylation of Aqp4 1 0.82 4 2.05
73 INT284846 Binding of Pdzd2 10 0.46 2.25 2.02
74 INT104564 Gene_expression of Aqp3 8 0.65 4.92 1.99
75 INT140171 Binding of Aqp4 7 0.36 11.63 1.98
76 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
77 INT138878 Negative_regulation of Gene_expression of Cldn5 4 0.37 2.81 1.96
78 INT87779 Positive_regulation of Gja1 4 0.53 0.9 1.95
79 INT238608 Gene_expression of Cask 1 0.73 2.74 1.9
80 INT148788 Binding of Csk 2 0.12 2.14 1.89
81 INT153719 Gene_expression of TEK 10 0.49 9.82 1.88
82 INT49432 Gene_expression of PTPRM 2 0.04 0.27 1.87
83 INT109059 Gene_expression of PRKCZ 2 0.65 0.64 1.87
84 INT117346 Positive_regulation of ADAM17 5 0.50 6.69 1.86
85 INT118511 Gene_expression of Pard3 5 0.57 0.76 1.86
86 INT87776 Positive_regulation of Phosphorylation of Gja1 3 0.62 0.71 1.86
87 INT14914 Regulation of Cdh5 5 0.52 4.59 1.85
88 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
89 INT48218 Gene_expression of KRIT1 16 0.75 7.59 1.8
90 INT124077 Negative_regulation of Ocln 13 0.57 8.62 1.8
91 INT22482 Negative_regulation of Gene_expression of CADM1 6 0.49 3.2 1.8
92 INT236956 Gene_expression of PDZD2 6 0.53 6.13 1.8
93 INT132837 Positive_regulation of Csk 5 0.45 1.75 1.79
94 INT98580 Positive_regulation of CADM1 11 0.49 10.16 1.78
95 INT247811 Regulation of Gene_expression of Cxadr 2 0.34 2.61 1.77
96 INT130874 Negative_regulation of Gene_expression of ADAM17 3 0.43 5.03 1.76
97 INT168602 Negative_regulation of Itgb1 3 0.21 1.29 1.73
98 INT111944 Phosphorylation of VCL 3 0.73 5.23 1.72
99 INT115309 Gene_expression of Slc2a1 6 0.75 2.85 1.64
100 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
101 INT148937 Positive_regulation of Csk 2 0.13 2.25 1.63
102 INT114628 Positive_regulation of Gene_expression of SGCA 4 0.42 2.2 1.62
103 INT346404 Gene_expression of Sv2a 1 0.72 3.2 1.62
104 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
105 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
106 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
107 INT118149 Positive_regulation of Binding of Prkcz 1 0.09 0.58 1.54
108 INT164480 Negative_regulation of Gene_expression of Aqp4 14 0.58 10.84 1.52
109 INT209307 Positive_regulation of Gene_expression of Trpc4 1 0.58 0.59 1.52
110 INT120227 Binding of Cxadr 17 0.45 8.02 1.51
111 INT177305 Positive_regulation of Gene_expression of CXADR 7 0.48 1.1 1.51
112 INT87272 Binding of KRIT1 4 0.47 1.2 1.48
113 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
114 INT62015 Gene_expression of Sv2a 3 0.30 0.99 1.45
115 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
116 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
117 INT118150 Positive_regulation of Positive_regulation of Prkcz 1 0.08 0.49 1.42
118 INT21523 Positive_regulation of Ctnnd1 1 0.27 0.35 1.4
119 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39
120 INT155345 Negative_regulation of Phosphorylation of Aqp4 1 0.43 2.86 1.37
121 INT105286 Negative_regulation of Gene_expression of Ocln 7 0.31 2.52 1.35
122 INT152964 Regulation of Gene_expression of Aqp4 3 0.56 4.18 1.34
123 INT140647 Gene_expression of DSG1 45 0.75 27.95 1.33
124 INT161903 Regulation of Cxadr 4 0.43 1.9 1.32
125 INT78861 Negative_regulation of Transcription of Adam17 2 0.29 1.4 1.32
126 INT78859 Transcription of Adam17 2 0.47 1.39 1.31
127 INT23668 Binding of Stx3 1 0.01 0 1.31
128 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
129 INT118682 Positive_regulation of KRIT1 4 0.67 1.25 1.24
130 INT182474 Gene_expression of Cdh5 17 0.57 14.58 1.23
131 INT60756 Gene_expression of Prkd1 2 0.58 0.14 1.23
132 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
133 INT122103 Negative_regulation of Cdh1 5 0.49 2.05 1.18
134 INT236958 Positive_regulation of PDZD2 1 0.07 4.24 1.17
135 INT98595 Regulation of ILK 6 0.62 3.84 1.16
136 INT337151 Positive_regulation of Gene_expression of Iqgap1 1 0.68 3.69 1.16
137 INT214235 Binding of CDSN 3 0.34 3.5 1.15
138 INT113865 Binding of CXADR 35 0.46 3.18 1.12
139 INT163914 Positive_regulation of Prkcd 1 0.67 1.43 1.12
140 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12
141 INT11934 Regulation of Sv2a 4 0.44 1.72 1.1
142 INT169704 Regulation of Gene_expression of Cdh1 4 0.35 1.75 1.09
143 INT105285 Regulation of Gene_expression of Tjp1 6 0.26 2.73 1.08
144 INT154437 Positive_regulation of Slc2a1 4 0.26 2.67 1.08
145 INT116406 Negative_regulation of CDSN 2 0.02 0.23 1.08
146 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
147 INT125904 Positive_regulation of Ocln 6 0.45 2.06 1.06
148 INT115481 Gene_expression of CDSN 6 0.10 2.53 1.03
149 INT151689 Positive_regulation of Gene_expression of CADM1 6 0.08 4.31 1.02
150 INT202378 Transcription of Aqp4 5 0.65 1.7 1.02
151 INT107874 Positive_regulation of Trpc4 3 0.58 0.09 1.02
152 INT132435 Negative_regulation of ADAM17 2 0.50 3.75 1.02
153 INT87273 Positive_regulation of Localization of KRIT1 1 0.67 0.1 1.02
154 INT190031 Binding of Scrib 19 0.36 21.9 1.01
155 INT105283 Positive_regulation of Gene_expression of Tjp1 4 0.68 1.86 1.01
156 INT242171 Protein_catabolism of JUP 4 0.96 0.91 1.01
157 INT142813 Localization of RPGRIP1L 1 0.59 0.99 1.01
158 INT134822 Gene_expression of Gja1 18 0.72 4.2 1
159 INT136271 Gene_expression of PNN 9 0.63 5.44 1
160 INT122141 Binding of Prkd1 4 0.27 0.66 1
161 INT122106 Localization of Cdh2 3 0.69 0.95 1
162 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
163 INT234952 Protein_catabolism of DSG1 3 0.96 5.86 0.98
164 INT78014 Negative_regulation of ITGA5 1 0.01 1.71 0.98
165 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
166 INT337150 Negative_regulation of Iqgap1 1 0.42 2.47 0.92
167 INT290265 Positive_regulation of FAT1 11 0.67 5.93 0.91
168 INT169592 Localization of FAT1 3 0.51 3.21 0.91
169 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
170 INT167763 Negative_regulation of Prkcz 1 0.04 0.32 0.88
171 INT148271 Regulation of SGCA 10 0.37 5.89 0.86
172 INT276620 Negative_regulation of Cdh1 7 0.57 6.48 0.86
173 INT113672 Positive_regulation of Gene_expression of ITGB1 3 0.49 1.4 0.86
174 INT120393 Negative_regulation of PRKCD 3 0.22 1.07 0.86
175 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
176 INT120396 Positive_regulation of Localization of PRKCD 1 0.26 0.42 0.85
177 INT132835 Phosphorylation of Csk 2 0.36 0 0.83
178 INT109060 Regulation of Gene_expression of PRKCZ 1 0.03 0 0.83
179 INT120392 Localization of PRKCD 1 0.39 0.4 0.83
180 INT167424 Positive_regulation of Pak1 1 0.14 1.43 0.83
181 INT141628 Gene_expression of Cadm1 22 0.78 4.71 0.82
182 INT259149 Gene_expression of DSG2 13 0.74 9.73 0.82
183 INT134748 Positive_regulation of SV2A 7 0.46 2.89 0.82
184 INT87777 Regulation of Gja1 1 0.62 0.76 0.81
185 INT111941 Regulation of Phosphorylation of VCL 1 0.27 0.66 0.8
186 INT111942 Positive_regulation of Phosphorylation of VCL 1 0.30 0.67 0.8
187 INT251063 Gene_expression of Cldn5 12 0.59 3.73 0.79
188 INT112780 Positive_regulation of Slc2a1 6 0.46 1.85 0.78
189 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
190 INT284840 Negative_regulation of Pdzd2 1 0.41 0.52 0.78
191 INT169591 Gene_expression of FAT1 23 0.67 10.73 0.77
192 INT65187 Positive_regulation of PNN 2 0.02 1.12 0.77
193 INT245796 Phosphorylation of Ocln 6 0.33 2.76 0.76
194 INT235953 Regulation of Binding of Aqp4 4 0.45 4.4 0.76
195 INT129556 Transcription of Trpc4 3 0.60 0.23 0.76
196 INT235951 Positive_regulation of Positive_regulation of Aqp4 4 0.57 5.13 0.75
197 INT143306 Positive_regulation of Gja1 3 0.50 0.42 0.75
198 INT23671 Negative_regulation of Stx3 1 0.01 0 0.75
199 INT172412 Negative_regulation of SV2A 6 0.47 0.88 0.74
200 INT128402 Negative_regulation of Phosphorylation of Gja1 1 0.58 0.73 0.73
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