GO:0005923

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Name tight junction
Categary Component
Go Slim No
Go Link GO:0005923
Unique Molecular Interactions 417
Total Molecular Interactions 619
Total Single Events 3544
Pain Genes Associated 58

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tight junction. They are ordered first by their pain relevance and then by number of times they were reported for tight junction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
2 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
3 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
4 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
5 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
6 INT122432 Prkci Regulation of Negative_regulation of Oprd1 1 0.01 0 1.06
7 INT154778 Cldn11 Positive_regulation of Eae1 4 0.12 3.24 1.03
8 INT122429 Prkci Regulation of Gene_expression of Ighm 1 0.00 0 1.02
9 INT122431 Prkci Negative_regulation of Negative_regulation of Ighm 1 0.00 0 1.02
10 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
11 INT122433 Prkci Negative_regulation of Ighm 1 0.00 0 1.02
12 INT167767 Prkcz Positive_regulation of Phosphorylation of Sigmar1 1 0.04 0.23 0.9
13 INT167766 Prkcz Positive_regulation of Positive_regulation of Sigmar1 1 0.04 0.23 0.9
14 INT155761 Binding of Nos1 and Tjp1 1 0.13 1.01 0.82
15 INT167770 Sigmar1 Positive_regulation of Prkcz 1 0.04 0.34 0.77
16 INT167768 Regulation of Sigmar1 Positive_regulation of Prkcz 1 0.02 0.34 0.77
17 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
18 INT332538 Binding of AD5 and Cxadr 1 0.08 0.98 0.76
19 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
20 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73
21 INT120819 Binding of ASIC3 and Lin7b 1 0.01 0 0.73
22 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
23 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
24 INT120818 Lin7b Positive_regulation of ASIC3 1 0.01 0 0.71
25 INT232622 Magi2 Regulation of Cysltr1 1 0.01 0.58 0.67
26 INT310712 Gabrg1 Positive_regulation of Gene_expression of PMP22 1 0.35 0.56 0.61
27 INT138886 Binding of F11r and Tjp1 1 0.13 0.86 0.6
28 INT177269 Binding of CXADR and NR1H4 1 0.04 0 0.58
29 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
30 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
31 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48
32 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
33 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
34 INT332539 Regulation of Binding of AD5 and Cxadr 1 0.09 0.65 0.44
35 INT104447 Ido1 Negative_regulation of Binding of Atp7b 1 0.00 0.68 0.43
36 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
37 INT139683 Binding of Cldn11 and 2410016O06Rik 1 0.02 1.06 0.4
38 INT338044 F2 Positive_regulation of Pard3 1 0.08 0.38 0.4
39 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
40 INT137625 Ntf3 Positive_regulation of Atp7b 1 0.04 0 0.36
41 INT239398 Atp7b Regulation of OAP 1 0.03 1.1 0.35
42 INT120817 Binding of Dlg4 and Lin7b 1 0.00 0 0.34
43 INT149191 TNF Positive_regulation of Gene_expression of ESAM 1 0.47 0.68 0.33
44 INT195665 APC Negative_regulation of F8 1 0.04 1.53 0.32
45 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
46 INT190806 Ubd Regulation of Abp1 1 0.20 0.82 0.32
47 INT296459 Binding of Dlg1 and Gria1 1 0.02 0.23 0.31
48 INT195664 APC Negative_regulation of F5 1 0.08 1.51 0.31
49 INT296453 Binding of Gria1 and Mpdz 1 0.02 0.23 0.31
50 INT63122 Binding of APC and Man2a2 1 0.01 0.15 0.3
51 INT130128 Binding of Ocln and Tjp1 2 0.38 0.98 0.29
52 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28
53 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27
54 INT101371 Inadl Positive_regulation of Gene_expression of ASIC3 1 0.02 0.46 0.27
55 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
56 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
57 INT239396 Atp7b Negative_regulation of Gene_expression of Icam1 1 0.07 1.69 0.26
58 INT348755 Plat Regulation of Gene_expression of Cldn5 1 0.10 0.45 0.25
59 INT274942 Binding of Dlg1 and Ephb6 1 0.05 0 0.25
60 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24
61 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24
62 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
63 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
64 INT109408 Negative_regulation of APC Negative_regulation of Positive_regulation of RASGRP1 1 0.06 0.73 0.23
65 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
66 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23
67 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
68 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22
69 INT195663 APC Negative_regulation of Gene_expression of IL6 1 0.16 1.18 0.22
70 INT53902 Atp7b Positive_regulation of Scn7a 1 0.04 0 0.21
71 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2
72 INT273048 Adcyap1 Positive_regulation of Adcyap1r1 1 0.11 1.02 0.19
73 INT217528 Binding of Tjp1 and Vapb 1 0.00 1.6 0.19
74 INT308533 ITIH4 Positive_regulation of Protein_catabolism of Tjp2 1 0.01 1.28 0.18
75 INT149798 Atp7b Positive_regulation of Trpa1 1 0.23 0.18 0.17
76 INT256985 Binding of Dlg1 and Cd81 1 0.39 0.2 0.17
77 INT334106 APC Negative_regulation of NFKB1 1 0.25 1.37 0.17
78 INT334108 APC Negative_regulation of TNF 1 0.13 1.36 0.17
79 INT343850 Binding of TRAF4 and TICAM1 1 0.03 0.19 0.17
80 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16
81 INT239393 Atp7b Positive_regulation of Gene_expression of Amigo2 1 0.03 1.37 0.16
82 INT239395 Atp7b Positive_regulation of Amigo2 1 0.03 1.36 0.16
83 INT239394 Atp7b Positive_regulation of Positive_regulation of Amigo2 1 0.03 1.36 0.16
84 INT349850 Gfra1 Negative_regulation of Adcyap1r1 1 0.15 0.36 0.15
85 INT349851 Gfra3 Negative_regulation of Adcyap1r1 1 0.28 0.31 0.15
86 INT349849 Gfra2 Negative_regulation of Adcyap1r1 1 0.33 0.31 0.15
87 INT106994 PARD3 Positive_regulation of PAR4 1 0.21 0.28 0.14
88 INT345171 Binding of Trip6 and Magi3 1 0.03 1.65 0.14
89 INT107006 PARD3 Positive_regulation of SPG21 1 0.24 0.29 0.14
90 INT332540 Cxadr Regulation of Gene_expression of AD5 1 0.09 0.25 0.14
91 INT326385 Mtdh Regulation of Gdnf 1 0.00 0.41 0.14
92 INT289956 Binding of APC and ICAM1 1 0.04 0.5 0.13
93 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13
94 INT106997 PARD3 Positive_regulation of NR1I2 1 0.19 0.28 0.13
95 INT184603 APC Negative_regulation of Gene_expression of TNF 1 0.09 0.97 0.13
96 INT315388 Binding of Adcyap1r1 and Adcyap1 1 0.02 0.5 0.12
97 INT316190 Apc Negative_regulation of Positive_regulation of Mapk1 1 0.33 0.66 0.12
98 INT354718 Binding of INADL and Myo18a 1 0.00 0.13 0.12
99 INT184608 APC Regulation of Gene_expression of Nppa 1 0.06 1.11 0.12
100 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11
101 INT338041 F2r Positive_regulation of Pard3 1 0.15 0.05 0.11
102 INT338048 F2rl3 Positive_regulation of Pard3 1 0.11 0.05 0.11
103 INT217530 Binding of Tjp1 and Tjp2 1 0.10 0.91 0.1
104 INT262255 Binding of APC and F2R 1 0.05 3 0.1
105 INT265346 Binding of Ocln and Tjp1 7 0.05 1.11 0.09
106 INT254492 Dtx1 Regulation of Cldn11 1 0.03 0 0.09
107 INT355584 VEGFA Positive_regulation of Positive_regulation of CDH5 1 0.06 1.35 0.09
108 INT312844 Pou3f1 Regulation of Gene_expression of Pmp22 1 0.27 0.16 0.09
109 INT177296 Binding of CXADR and CYP3A4 1 0.30 0 0.09
110 INT257665 Binding of Nphs1 and Pard3 1 0.39 0.67 0.09
111 INT312846 Egr2 Regulation of Gene_expression of Pmp22 1 0.35 0.16 0.09
112 INT307665 Binding of Mpz and Pmp22 1 0.34 0.39 0.08
113 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
114 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08
115 INT307666 Binding of Pmp22 and Gjb1 1 0.31 0.38 0.08
116 INT307663 Binding of Pmp22 and Egr2 1 0.33 0.39 0.08
117 INT307664 Binding of Pmp22 and LOC689781 1 0.03 0.39 0.08
118 INT270197 Binding of Apc and Cd86 1 0.02 0.58 0.08
119 INT270198 Binding of Apc and Cd80 1 0.02 0.58 0.08
120 INT205244 Cldn3 Regulation of Gene_expression of Ocln 1 0.04 0.29 0.07
121 INT205237 Cldn2 Regulation of Gene_expression of Cldn5 1 0.03 0.29 0.07
122 INT205238 Cldn3 Regulation of Gene_expression of Cldn2 1 0.03 0.29 0.07
123 INT205228 Cldn5 Regulation of Gene_expression of Cldn1 1 0.03 0.29 0.07
124 INT205245 Cldn5 Regulation of Gene_expression of Cldn3 1 0.02 0.29 0.07
125 INT205229 Cldn2 Regulation of Gene_expression of Ocln 1 0.07 0.29 0.07
126 INT205236 Cldn5 Regulation of Tjp1 1 0.03 0.28 0.07
127 INT205239 Cldn3 Regulation of Gene_expression of Cldn5 1 0.02 0.29 0.07
128 INT205240 Cldn3 Regulation of Tjp1 1 0.04 0.29 0.07
129 INT205231 Cldn2 Regulation of Tjp1 1 0.07 0.29 0.07
130 INT205248 Cldn2 Regulation of Gene_expression of Tjp1 1 0.07 0.29 0.07
131 INT205232 Cldn5 Regulation of Gene_expression of Cldn2 1 0.03 0.29 0.07
132 INT205235 Cldn2 Regulation of Gene_expression of Cldn1 1 0.06 0.29 0.07
133 INT205233 Cldn5 Regulation of Gene_expression of Ocln 1 0.03 0.28 0.07
134 INT205227 Cldn3 Regulation of Gene_expression of Cldn1 1 0.03 0.29 0.07
135 INT205247 Cldn3 Regulation of Gene_expression of Tjp1 1 0.04 0.29 0.07
136 INT205246 Cldn5 Regulation of Gene_expression of Tjp1 1 0.03 0.28 0.07
137 INT205234 Cldn2 Regulation of Gene_expression of Cldn3 1 0.03 0.29 0.07
138 INT311915 Tgfbr1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
139 INT156144 MLL Positive_regulation of Epcam 1 0.00 0.47 0.06
140 INT346752 Binding of Dlg1 and Gria1 1 0.02 0 0.06
141 INT190750 Adcyap1 Regulation of Positive_regulation of Adcyap1r1 1 0.11 0 0.06
142 INT178984 Gmeb1 Positive_regulation of CXADR 1 0.00 0 0.05
143 INT176095 Binding of Apc and EC 1 0.04 0.51 0.05
144 INT177260 CXADR Positive_regulation of SLCO1B1 1 0.34 0 0.05
145 INT265564 Ocln Regulation of Gene_expression of Cdh5 1 0.01 1.03 0.05
146 INT177276 Positive_regulation of Binding of CXADR and NR1H4 1 0.04 0 0.05
147 INT178985 Positive_regulation of Gmeb1 Positive_regulation of CXADR 1 0.00 0 0.05
148 INT177282 Regulation of Binding of CXADR and NR1H4 1 0.02 0 0.05
149 INT177291 CXADR Positive_regulation of ABCC2 1 0.22 0 0.05
150 INT177295 Binding of CXADR and ABCB1 1 0.30 0 0.05
151 INT120574 Binding of Apc and Egfr 1 0.27 1.02 0.05
152 INT177288 Binding of CXADR and SV2A 1 0.32 0 0.04
153 INT334107 Binding of APC and APCS 1 0.16 1.52 0.04
154 INT177279 Binding of CXADR and TNFRSF25 1 0.18 0 0.04
155 INT177268 Binding of CXADR and HLA-DRB4 1 0.20 0 0.04
156 INT177281 Binding of CA2 and CXADR 1 0.31 0 0.04
157 INT305876 ras Regulation of Regulation of Tjp2 1 0.00 0.39 0.04
158 INT355224 Phosphorylation of Ocln Negative_regulation of Binding of Tjp2 1 0.06 0.09 0.04
159 INT355219 Phosphorylation of Ocln Positive_regulation of Binding of Tjp2 1 0.07 0.09 0.04
160 INT217529 Dss1 Negative_regulation of Gene_expression of Tjp1 1 0.07 0.54 0.04
161 INT268652 Binding of CLDN4 and LIF 1 0.35 0.44 0.04
162 INT305883 Pcx Negative_regulation of Binding of Tjp1 1 0.04 0.11 0.04
163 INT305875 Pcx Negative_regulation of Binding of Ocln 1 0.03 0.11 0.04
164 INT247819 Cxadr Regulation of Gene_expression of Rasa1 1 0.06 1.04 0.04
165 INT177253 Binding of CXADR and FAUP1 1 0.02 0 0.04
166 INT317959 Negative_regulation of Ephb1 Negative_regulation of Cldn4 1 0.10 0.27 0.03
167 INT266617 Binding of GJC1 and Tjp1 1 0.41 0.28 0.03
168 INT217858 AD5 Positive_regulation of Gene_expression of CXADR 1 0.17 0.65 0.03
169 INT265347 Binding of Ocln and Tgfbr1 1 0.18 0.06 0.03
170 INT177258 SV2A Regulation of CXADR 1 0.63 0 0.03
171 INT265345 Binding of Tgfbr1 and Tjp1 1 0.09 0.06 0.03
172 INT251074 Cldn3 Regulation of Protein_catabolism of Alms1 1 0.09 0 0.03
173 INT348757 Plat Negative_regulation of Cldn5 1 0.16 0.3 0.03
174 INT317961 Negative_regulation of Ephb1 Negative_regulation of Negative_regulation of Cldn4 1 0.10 0.27 0.03
175 INT265343 Positive_regulation of Binding of Tgfbr1 and Tjp1 1 0.12 0.06 0.03
176 INT330484 Binding of Cxadr and Hspg2 1 0.18 0.52 0.03
177 INT311732 Plat Positive_regulation of Gene_expression of Esam 1 0.07 0.59 0.03
178 INT265348 Positive_regulation of Binding of Ocln and Tgfbr1 1 0.25 0.06 0.03
179 INT298858 Positive_regulation of Binding of VAPA and RILP 1 0.07 0.54 0
180 INT251071 Cldn3 Negative_regulation of Alms1 1 0.09 0.26 0
181 INT290592 Binding of KDR and Cdh5 1 0.07 0.08 0
182 INT213034 Hdl1 Positive_regulation of Apc 1 0.08 1.21 0
183 INT251073 Cldn3 Negative_regulation of Localization of Cldn5 1 0.35 0.26 0
184 INT177277 CXADR Positive_regulation of CYP2B6 1 0.47 0 0
185 INT177254 Binding of CXADR and NCOA2 1 0.19 0 0
186 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
187 INT263726 Binding of Dlg1 and Dlg4 1 0.04 0 0
188 INT217857 Binding of CXADR and AD5 1 0.18 3.55 0
189 INT247821 Binding of Tjp1 and Gopc 1 0.03 0.4 0
190 INT341502 Negative_regulation of Binding of Apc and Pdcd1 1 0.00 0.53 0
191 INT290590 Binding of Cdh5 and Prom1 1 0.05 0.08 0
192 INT238575 Binding of Cask and Magi1 1 0.04 0.17 0
193 INT256988 Binding of Dlg1 and Rpe 1 0.06 0 0
194 INT241852 Binding of EPO and EPCAM 1 0.06 0.84 0
195 INT349050 Binding of EPCAM and ZNF845 1 0.02 1.54 0
196 INT355220 Negative_regulation of Binding of Ocln and Tjp1 1 0.21 0.14 0
197 INT104029 RPGRIP1L Negative_regulation of Gene_expression of LTB 1 0.16 0.06 0
198 INT337915 Tgfbr1 Positive_regulation of Negative_regulation of Smad2 1 0.05 0.15 0
199 INT177283 Binding of CXADR and GOPC 1 0.16 0 0
200 INT265344 sb Negative_regulation of Tgfbr1 1 0.00 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for tight junction. They are ordered first by their pain relevance and then by number of times they were reported in tight junction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11897 Gene_expression of Atp7b 25 0.13 7.85 12.5
2 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
3 INT78320 Gene_expression of EPCAM 57 0.75 50.34 7.53
4 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
5 INT21938 Positive_regulation of Atp7b 26 0.10 11.33 7.1
6 INT83952 Gene_expression of Cxadr 24 0.75 22.38 6.77
7 INT118151 Positive_regulation of Prkcz 5 0.12 2.35 6.41
8 INT11896 Negative_regulation of Atp7b 15 0.11 6.01 6.09
9 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
10 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
11 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
12 INT105284 Gene_expression of Ocln 39 0.78 14.98 5.08
13 INT105289 Gene_expression of Tjp1 28 0.76 11.72 4.67
14 INT20196 Negative_regulation of Gene_expression of Atp7b 8 0.07 2.49 4.63
15 INT63651 Gene_expression of Adcyap1r1 17 0.77 2.57 4.58
16 INT36767 Localization of Atp7b 11 0.20 4.13 4.5
17 INT125447 Positive_regulation of CLDN4 14 0.70 4.71 4.45
18 INT119203 Gene_expression of CXADR 64 0.74 11.37 4.41
19 INT64157 Positive_regulation of EPCAM 11 0.44 9.09 4.24
20 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
21 INT63121 Binding of APC 29 0.41 23.02 3.8
22 INT78203 Gene_expression of PMP22 12 0.63 7.49 3.58
23 INT817 Negative_regulation of Abp1 15 0.49 4.25 3.56
24 INT93468 Gene_expression of Cldn1 15 0.27 10.12 3.51
25 INT28583 Positive_regulation of Gene_expression of Atp7b 4 0.06 0.34 3.24
26 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
27 INT125901 Gene_expression of Cldn3 10 0.41 7.27 3.06
28 INT118156 Binding of Prkcz 2 0.08 2.68 2.89
29 INT14106 Positive_regulation of Abp1 4 0.51 3.85 2.78
30 INT169323 Positive_regulation of Gene_expression of Cxadr 4 0.67 4.09 2.77
31 INT138882 Gene_expression of F11r 3 0.48 4.73 2.72
32 INT125905 Gene_expression of Cldn5 7 0.57 4.33 2.66
33 INT5432 Regulation of Atp7b 7 0.36 0.87 2.65
34 INT122424 Gene_expression of Prkci 1 0.58 0 2.56
35 INT139169 Gene_expression of Pmp22 10 0.68 8.37 2.5
36 INT177328 Positive_regulation of CXADR 9 0.48 4.29 2.27
37 INT125902 Positive_regulation of Gene_expression of Cldn5 5 0.51 3.13 2.16
38 INT205216 Gene_expression of Cldn4 47 0.53 9.47 2.08
39 INT149031 Gene_expression of Tjp1 43 0.75 19.1 2.06
40 INT122423 Negative_regulation of Gene_expression of Prkci 1 0.43 0 2.04
41 INT125451 Gene_expression of CLDN4 5 0.78 4.75 2.01
42 INT152771 Gene_expression of TJP1 19 0.75 14.95 1.98
43 INT181107 Gene_expression of Epcam 45 0.73 44.33 1.96
44 INT138878 Negative_regulation of Gene_expression of Cldn5 4 0.37 2.81 1.96
45 INT109059 Gene_expression of PRKCZ 2 0.65 0.64 1.87
46 INT118511 Gene_expression of Pard3 5 0.57 0.76 1.86
47 INT14914 Regulation of Cdh5 5 0.52 4.59 1.85
48 INT44320 Positive_regulation of Cldn11 5 0.39 2.95 1.81
49 INT124077 Negative_regulation of Ocln 13 0.57 8.62 1.8
50 INT67253 Gene_expression of Pmp22 4 0.33 6.48 1.79
51 INT247811 Regulation of Gene_expression of Cxadr 2 0.34 2.61 1.77
52 INT241858 Localization of EPCAM 3 0.47 5.27 1.76
53 INT231373 Negative_regulation of Pmp22 1 0.26 2.98 1.75
54 INT3818 Regulation of Apc 13 0.39 12.52 1.68
55 INT38998 Negative_regulation of Localization of Atp7b 4 0.11 1.72 1.6
56 INT64156 Negative_regulation of EPCAM 7 0.37 4.24 1.54
57 INT118149 Positive_regulation of Binding of Prkcz 1 0.09 0.58 1.54
58 INT120227 Binding of Cxadr 17 0.45 8.02 1.51
59 INT177305 Positive_regulation of Gene_expression of CXADR 7 0.48 1.1 1.51
60 INT118150 Positive_regulation of Positive_regulation of Prkcz 1 0.08 0.49 1.42
61 INT62820 Gene_expression of ESAM 8 0.76 3.2 1.41
62 INT72249 Negative_regulation of ABP1 6 0.36 1.08 1.41
63 INT18937 Positive_regulation of Cldn3 4 0.28 0.82 1.39
64 INT220177 Binding of Apc 21 0.37 15.34 1.37
65 INT72248 Binding of ABP1 7 0.29 4.33 1.36
66 INT105286 Negative_regulation of Gene_expression of Ocln 7 0.31 2.52 1.35
67 INT161903 Regulation of Cxadr 4 0.43 1.9 1.32
68 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
69 INT125446 Negative_regulation of Positive_regulation of CLDN4 2 0.59 2.14 1.3
70 INT138884 Positive_regulation of Gene_expression of F11r 1 0.29 1.81 1.25
71 INT182474 Gene_expression of Cdh5 17 0.57 14.58 1.23
72 INT241861 Regulation of EPCAM 7 0.17 7.23 1.22
73 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
74 INT102073 Regulation of Gene_expression of APC 5 0.45 6.09 1.15
75 INT78319 Binding of EPCAM 8 0.36 10.12 1.14
76 INT113865 Binding of CXADR 35 0.46 3.18 1.12
77 INT62440 Localization of Abp1 1 0.37 1.12 1.11
78 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1
79 INT101364 Gene_expression of Inadl 8 0.06 1.84 1.09
80 INT231379 Negative_regulation of Negative_regulation of Pmp22 1 0.26 1.72 1.09
81 INT105285 Regulation of Gene_expression of Tjp1 6 0.26 2.73 1.08
82 INT125904 Positive_regulation of Ocln 6 0.45 2.06 1.06
83 INT238495 Negative_regulation of Gene_expression of TJP1 5 0.18 9.51 1.05
84 INT209218 Gene_expression of Dlg1 3 0.54 0.42 1.03
85 INT125448 Positive_regulation of Gene_expression of CLDN4 3 0.70 1.01 1.02
86 INT122421 Phosphorylation of Prkci 1 0.47 0 1.02
87 INT105283 Positive_regulation of Gene_expression of Tjp1 4 0.68 1.86 1.01
88 INT142813 Localization of RPGRIP1L 1 0.59 0.99 1.01
89 INT28582 Positive_regulation of Positive_regulation of Atp7b 1 0.04 0.1 1
90 INT254471 Gene_expression of Cldn11 1 0.49 0.8 0.96
91 INT117254 Regulation of Gene_expression of PMP22 2 0.37 0.81 0.93
92 INT148293 Positive_regulation of Gene_expression of Pmp22 1 0.30 1.58 0.92
93 INT217506 Gene_expression of Tjp2 8 0.32 5.26 0.89
94 INT242134 Localization of Apc 8 0.74 4.83 0.88
95 INT210276 Positive_regulation of Gene_expression of PMP22 3 0.46 1.58 0.88
96 INT167763 Negative_regulation of Prkcz 1 0.04 0.32 0.88
97 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
98 INT71970 Positive_regulation of Adcyap1r1 6 0.14 0.49 0.84
99 INT109060 Regulation of Gene_expression of PRKCZ 1 0.03 0 0.83
100 INT93467 Positive_regulation of Gene_expression of Cldn1 2 0.17 1.49 0.82
101 INT32188 Regulation of Atp7b 7 0.04 3.01 0.81
102 INT205213 Positive_regulation of Gene_expression of Cldn4 12 0.47 3.37 0.8
103 INT251063 Gene_expression of Cldn5 12 0.59 3.73 0.79
104 INT52373 Positive_regulation of Adcyap1r1 1 0.00 0.3 0.78
105 INT245796 Phosphorylation of Ocln 6 0.33 2.76 0.76
106 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
107 INT171585 Positive_regulation of INADL 3 0.40 0.61 0.75
108 INT174158 Negative_regulation of Cxadr 23 0.55 13.74 0.72
109 INT153565 Gene_expression of PRKCI 1 0.75 0 0.72
110 INT261004 Negative_regulation of Cldn1 3 0.19 3.27 0.71
111 INT120815 Gene_expression of Lin7b 1 0.01 0 0.71
112 INT201257 Positive_regulation of VAPA 1 0.01 0 0.71
113 INT57062 Regulation of APC 24 0.58 14.3 0.7
114 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69
115 INT87445 Localization of TJP1 2 0.45 0.55 0.68
116 INT120816 Binding of Lin7b 1 0.01 0 0.68
117 INT113866 Regulation of CXADR 7 0.59 1.67 0.67
118 INT152775 Regulation of Gene_expression of TJP1 1 0.44 2.05 0.67
119 INT205206 Gene_expression of Cldn2 17 0.27 3.4 0.66
120 INT305872 Negative_regulation of Gene_expression of Cldn5 2 0.20 2.49 0.65
121 INT177316 Localization of CXADR 9 0.77 1.05 0.64
122 INT209898 Gene_expression of TRAF4 1 0.52 2.11 0.64
123 INT138885 Negative_regulation of Gene_expression of F11r 1 0.25 0.93 0.64
124 INT159141 Negative_regulation of Gene_expression of Tjp1 7 0.57 5.44 0.62
125 INT149155 Positive_regulation of Pmp22 1 0.15 0.08 0.62
126 INT149154 Positive_regulation of Gene_expression of Pmp22 1 0.15 0.08 0.62
127 INT125449 Regulation of Gene_expression of CLDN4 2 0.60 1.07 0.61
128 INT153568 Binding of PRKCI 1 0.36 0 0.6
129 INT190734 Transcription of Adcyap1r1 1 0.19 0.1 0.6
130 INT139677 Localization of Cldn11 3 0.59 1.42 0.58
131 INT122420 Regulation of Prkci 1 0.44 0 0.58
132 INT159143 Gene_expression of Ocln 14 0.42 5.25 0.57
133 INT256048 Negative_regulation of Gene_expression of EPCAM 7 0.41 4.37 0.57
134 INT158898 Positive_regulation of Gene_expression of Ocln 5 0.22 2.06 0.57
135 INT144922 Gene_expression of TGFBR1 4 0.72 0.19 0.57
136 INT72869 Regulation of Negative_regulation of APC 2 0.36 1.7 0.54
137 INT125135 Regulation of Gene_expression of ESAM 1 0.23 1.56 0.54
138 INT104446 Binding of Atp7b 2 0.09 0.77 0.53
139 INT62825 Positive_regulation of Gene_expression of ESAM 2 0.40 0.81 0.53
140 INT125445 Positive_regulation of Positive_regulation of CLDN4 1 0.70 0.52 0.53
141 INT191287 Positive_regulation of ABP1 6 0.39 3.72 0.51
142 INT154775 Binding of Cldn11 1 0.36 1.92 0.51
143 INT159140 Positive_regulation of Gene_expression of Tjp1 11 0.61 5.04 0.5
144 INT242444 Positive_regulation of Cldn5 2 0.24 0.99 0.5
145 INT101365 Binding of Tjp1 8 0.11 1.66 0.49
146 INT81550 Binding of Pmp22 4 0.35 4.2 0.49
147 INT158891 Positive_regulation of Gene_expression of Cldn3 3 0.25 1.23 0.49
148 INT239390 Positive_regulation of Phosphorylation of Atp7b 1 0.39 3.49 0.49
149 INT120226 Positive_regulation of Cxadr 4 0.44 2.54 0.48
150 INT304633 Positive_regulation of Phosphorylation of Ocln 2 0.28 0.19 0.47
151 INT62659 Regulation of Localization of Atp7b 1 0.00 0.45 0.47
152 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46
153 INT125450 Negative_regulation of Gene_expression of CLDN4 1 0.43 0.47 0.46
154 INT44319 Positive_regulation of Positive_regulation of Cldn11 1 0.39 0.12 0.46
155 INT159146 Regulation of Gene_expression of Tjp1 13 0.44 6.91 0.45
156 INT61822 Negative_regulation of Ocln 8 0.41 5.33 0.45
157 INT247794 Localization of Cxadr 4 0.76 3.17 0.45
158 INT110477 Positive_regulation of Localization of PRKCZ 1 0.20 0.07 0.45
159 INT304648 Negative_regulation of Cldn3 1 0.23 1.22 0.45
160 INT304642 Negative_regulation of F11r 1 0.12 1.22 0.45
161 INT188173 Gene_expression of CDH5 14 0.49 3.17 0.44
162 INT34154 Regulation of Gene_expression of Atp7b 1 0.00 0.28 0.44
163 INT110479 Localization of PRKCZ 1 0.35 0.07 0.43
164 INT152151 Regulation of Gene_expression of Apc 4 0.44 3.87 0.42
165 INT191288 Gene_expression of ABP1 7 0.52 6.61 0.4
166 INT2018 Regulation of Adcyap1r1 2 0.44 0.3 0.4
167 INT348754 Negative_regulation of Cldn5 1 0.17 0.75 0.4
168 INT292484 Negative_regulation of TGFBR1 3 0.19 0.75 0.39
169 INT215086 Positive_regulation of Inadl 2 0.01 2.13 0.39
170 INT110478 Regulation of PRKCZ 1 0.20 0.1 0.37
171 INT245272 Gene_expression of Cldn3 8 0.62 1.73 0.36
172 INT158887 Negative_regulation of Gene_expression of Cldn3 2 0.27 0.7 0.36
173 INT73145 Binding of Abp1 2 0.07 0.17 0.36
174 INT205205 Regulation of Gene_expression of Cldn4 1 0.42 1.27 0.36
175 INT205215 Localization of Tjp1 2 0.29 0.95 0.35
176 INT220170 Regulation of Positive_regulation of Apc 1 0.10 0.46 0.35
177 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34
178 INT159145 Negative_regulation of Gene_expression of Ocln 4 0.32 3.07 0.34
179 INT62828 Negative_regulation of Gene_expression of ESAM 3 0.57 0.4 0.34
180 INT153495 Binding of Pmp22 3 0.37 2.51 0.34
181 INT124076 Binding of Ocln 3 0.37 1.01 0.34
182 INT118243 Transcription of APC 4 0.45 3.33 0.33
183 INT184605 Positive_regulation of Transcription of APC 2 0.19 2.39 0.33
184 INT239386 Gene_expression of Atp7b 4 0.52 3.24 0.32
185 INT205218 Localization of Ocln 3 0.46 1.71 0.32
186 INT225667 Transcription of Apc 3 0.52 3.73 0.32
187 INT101366 Regulation of Inadl 2 0.02 0.48 0.32
188 INT190805 Positive_regulation of Positive_regulation of Abp1 1 0.39 0.82 0.32
189 INT190725 Regulation of Gene_expression of Adcyap1r1 1 0.13 0 0.32
190 INT284117 Protein_catabolism of Epcam 2 0.43 3.01 0.31
191 INT205217 Negative_regulation of Gene_expression of Cldn4 1 0.40 1.22 0.31
192 INT195672 Localization of APC 7 0.74 3.76 0.3
193 INT110772 Binding of Tjp1 2 0.32 1.12 0.3
194 INT101367 Transcription of Inadl 1 0.05 0.49 0.3
195 INT339435 Binding of Cdh5 1 0.31 3.37 0.3
196 INT264637 Localization of CLDN4 3 0.73 0.85 0.29
197 INT291084 Localization of Cldn5 1 0.31 0.84 0.29
198 INT311881 Regulation of Positive_regulation of Tgfbr1 1 0.22 0.97 0.29
199 INT34827 Regulation of ABP1 1 0.62 0.24 0.29
200 INT217501 Positive_regulation of Tjp1 8 0.49 2.91 0.28
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