GO:0005932

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Name microtubule basal body
Categary Component
Go Slim No
Go Link GO:0005932
Unique Molecular Interactions 69
Total Molecular Interactions 99
Total Single Events 635
Pain Genes Associated 21

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for microtubule basal body. They are ordered first by their pain relevance and then by number of times they were reported for microtubule basal body. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7
2 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52
3 INT104016 RPGR Positive_regulation of Gene_expression of FOS 1 0.16 0 0.43
4 INT28237 BBS2 Positive_regulation of Localization of Cck 1 0.04 0.33 0.39
5 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
6 INT263072 Kncn Regulation of Transcription of Trpm8 1 0.08 0.99 0.36
7 INT93989 Rab8a Positive_regulation of Gene_expression of Il12a 1 0.10 0.48 0.3
8 INT93986 Rab8a Positive_regulation of Gene_expression of Il6 1 0.08 0.48 0.3
9 INT93988 Rab8a Regulation of Hand2 1 0.09 0.78 0.3
10 INT37157 Pir Positive_regulation of Kncn 1 0.01 0.38 0.3
11 INT93990 Rab8a Positive_regulation of Gene_expression of Il1 1 0.05 0.48 0.3
12 INT93987 Positive_regulation of Rab8a Positive_regulation of Localization of Ifng 1 0.10 0.38 0.29
13 INT353632 Binding of Shbdp1 and Kncn 1 0.05 0 0.28
14 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
15 INT215955 Binding of alp and Cys1 1 0.00 0.95 0.22
16 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
17 INT241250 Binding of Pkd2 and Trpc1 1 0.23 0.3 0.17
18 INT326390 Binding of PROC and Ezr 1 0.00 1 0.17
19 INT22320 Binding of Cys1 and sch 1 0.02 0.45 0.15
20 INT325952 Gene_expression of Ezr Positive_regulation of Mapk1 1 0.02 1.69 0.15
21 INT326379 Binding of Ezr and Slc9a3r2 2 0.03 0.34 0.13
22 INT241248 Binding of Pkd1 and Pkd2 3 0.22 1.52 0.1
23 INT352751 Pkd2 Regulation of Localization of Vegfa 1 0.11 0.47 0.1
24 INT352750 Pkd2 Positive_regulation of Vegfa 1 0.20 0.47 0.1
25 INT241249 Pkd2 Regulation of Trpc1 1 0.21 0.14 0.09
26 INT286565 Pkd2 Positive_regulation of Positive_regulation of Pkd1 1 0.21 0.11 0.09
27 INT241246 Pkd2 Negative_regulation of Gene_expression of Trpv4 1 0.48 0.47 0.07
28 INT175992 TNF Positive_regulation of Gene_expression of Cys1 1 0.01 0.34 0.07
29 INT325954 Binding of Cttn and Ezr 1 0.22 1.61 0.07
30 INT326377 Ezr Positive_regulation of Positive_regulation of Rhoa 1 0.05 0.16 0.06
31 INT350010 Binding of IL6 and AHI1 1 0.01 0.29 0.06
32 INT167271 Binding of Ezr and Clic5 1 0.54 0.07 0.06
33 INT326378 Binding of Rhoa and Ezr 1 0.04 0.17 0.06
34 INT340427 Positive_regulation of P2rx7 Positive_regulation of Regulation of Pkhd1 1 0.01 1 0.05
35 INT241253 Gene_expression of Trpv4 Positive_regulation of Gene_expression of Pkd2 1 0.52 0.29 0.03
36 INT241251 Pkd2 Negative_regulation of Gene_expression of Gopc 1 0.12 0.24 0.03
37 INT354617 Binding of Ezr and Gpbar1 1 0.02 0 0.03
38 INT325945 Binding of Cd44 and Ezr 1 0.25 0.39 0
39 INT200058 Binding of Ndn and Bbs4 1 0.30 0.29 0
40 INT352148 Ift88 Negative_regulation of Bcl2l2 1 0.00 0.19 0
41 INT325942 Binding of Icam1 and Ezr 1 0.15 0.39 0
42 INT325949 Binding of Spn and Ezr 1 0.14 0.39 0
43 INT273106 Binding of Mtor and Cby1 1 0.01 0 0
44 INT104029 RPGRIP1L Negative_regulation of Gene_expression of LTB 1 0.16 0.06 0
45 INT200062 Binding of Ngfr and Bbs4 1 0.30 0.3 0
46 INT325948 Ezr Regulation of Pcx 1 0.00 0.84 0
47 INT261883 PKD2 Positive_regulation of Localization of Ca2 1 0.02 0.67 0
48 INT289510 Binding of ODF2 and Ezr 1 0.10 0.47 0
49 INT186401 Binding of MKKS and MKS1 1 0.09 0.07 0
50 INT286570 Pkd2 Positive_regulation of Binding of Pkd1 1 0.21 0.73 0
51 INT325953 Ezr Positive_regulation of Mapk1 1 0.02 0.4 0
52 INT321968 Rock1 Positive_regulation of EZR 1 0.42 1.02 0
53 INT325955 Ezr Regulation of Mia1 1 0.09 1.68 0
54 INT286589 Binding of PKHD1 and Pkd2 1 0.09 0.52 0
55 INT325946 Gene_expression of Ezr Positive_regulation of Positive_regulation of Mapk1 1 0.02 0.28 0
56 INT256983 Binding of Cd9 and Ezr 1 0.06 0.12 0
57 INT180470 Cdh23 Positive_regulation of Lpl 1 0.06 1.23 0
58 INT286573 Pkd2 Regulation of Pkd1 1 0.12 0.25 0
59 INT352150 Ift88 Negative_regulation of Bcl2 1 0.00 0.19 0
60 INT286590 Binding of ID2 and Pkd2 1 0.13 0.13 0
61 INT325947 Ezr Regulation of Zfp369 1 0.00 0.84 0
62 INT256989 Binding of Ezr and Slc9a3r1 1 0.10 0 0
63 INT325950 Binding of Icam2 and Ezr 1 0.17 0.39 0
64 INT186402 Binding of KCNA1 and MKS1 1 0.05 0.07 0
65 INT352149 Ift88 Negative_regulation of Bcl2l1 1 0.00 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for microtubule basal body. They are ordered first by their pain relevance and then by number of times they were reported in microtubule basal body. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47
2 INT9349 Gene_expression of BBS2 15 0.49 12.77 4.22
3 INT325930 Gene_expression of Ezr 75 0.77 59.77 4.06
4 INT199798 Positive_regulation of BBS2 2 0.50 5.85 2.55
5 INT4686 Gene_expression of Cys1 32 0.66 36.24 2.49
6 INT45202 Regulation of Cys1 8 0.08 5.62 2.23
7 INT263065 Gene_expression of Kncn 4 0.34 3.01 2.19
8 INT325940 Positive_regulation of Gene_expression of Ezr 42 0.69 27.79 1.56
9 INT263069 Regulation of Kncn 1 0.11 3.66 1.47
10 INT93980 Gene_expression of Rab8a 1 0.74 2.72 1.21
11 INT177481 Negative_regulation of BBS2 6 0.31 5.34 1.06
12 INT142813 Localization of RPGRIP1L 1 0.59 0.99 1.01
13 INT52595 Positive_regulation of Positive_regulation of Cys1 5 0.47 5.12 0.9
14 INT229278 Positive_regulation of Cby1 5 0.67 8.07 0.85
15 INT28236 Localization of BBS2 2 0.54 1.9 0.83
16 INT274178 Binding of BBS2 1 0.27 2.12 0.82
17 INT287270 Binding of Ezr 8 0.36 1.78 0.76
18 INT123290 Phosphorylation of Mks1 1 0.02 0.36 0.72
19 INT263063 Regulation of Gene_expression of Kncn 2 0.22 1.33 0.71
20 INT174517 Localization of AHI1 2 0.24 1.62 0.68
21 INT95337 Negative_regulation of AHI1 2 0.02 0.75 0.68
22 INT93981 Positive_regulation of Rab8a 1 0.66 1.41 0.67
23 INT1939 Localization of Cys1 6 0.73 5.9 0.64
24 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63
25 INT251632 Positive_regulation of Cdh23 1 0.00 0.27 0.63
26 INT46134 Positive_regulation of Gene_expression of Cys1 4 0.50 11.52 0.61
27 INT155210 Positive_regulation of Phosphorylation of MKS1 1 0.00 0.07 0.58
28 INT241235 Binding of Pkd2 11 0.48 2.43 0.55
29 INT155209 Phosphorylation of MKS1 1 0.00 0.07 0.55
30 INT241243 Gene_expression of Pkd2 30 0.77 9.05 0.53
31 INT180459 Gene_expression of Cdh23 4 0.14 5.11 0.52
32 INT175068 Localization of Ezr 1 0.19 0 0.5
33 INT274177 Positive_regulation of Gene_expression of BBS2 2 0.36 1.55 0.49
34 INT93985 Positive_regulation of Gene_expression of Rab8a 1 0.39 1.08 0.45
35 INT26601 Negative_regulation of Gene_expression of Cys1 1 0.36 2.26 0.45
36 INT93983 Binding of Rab8a 1 0.31 1.05 0.44
37 INT93982 Negative_regulation of Rab8a 1 0.35 1.08 0.44
38 INT2545 Negative_regulation of Cys1 6 0.17 3.22 0.43
39 INT93979 Negative_regulation of Gene_expression of Rab8a 1 0.48 1.03 0.42
40 INT130966 Binding of EZR 2 0.36 0.24 0.41
41 INT241236 Negative_regulation of Pkd2 11 0.43 1.82 0.39
42 INT289505 Negative_regulation of Ezr 2 0.43 3.04 0.35
43 INT14382 Regulation of BBS2 3 0.43 2.07 0.33
44 INT180456 Regulation of Cdh23 3 0.06 2.83 0.32
45 INT229279 Negative_regulation of Cby1 15 0.42 9.4 0.31
46 INT274176 Negative_regulation of Gene_expression of BBS2 1 0.31 0.94 0.29
47 INT93984 Positive_regulation of Positive_regulation of Rab8a 1 0.48 0.34 0.27
48 INT325934 Localization of Ezr 1 0.80 3.78 0.27
49 INT241238 Positive_regulation of Pkd2 5 0.46 1.44 0.24
50 INT151978 Negative_regulation of Positive_regulation of Cys1 3 0.41 4.15 0.24
51 INT241244 Localization of Pkd2 1 0.74 0.35 0.24
52 INT284157 Regulation of Negative_regulation of BBS2 1 0.08 1.08 0.21
53 INT16306 Binding of Cdh23 2 0.15 1.76 0.2
54 INT356020 Binding of MKS1 1 0.02 1.36 0.2
55 INT325939 Regulation of Gene_expression of Ezr 1 0.61 5.27 0.19
56 INT152521 Gene_expression of Ezr 1 0.47 2.95 0.18
57 INT296875 Positive_regulation of AHI1 2 0.15 3.53 0.16
58 INT272845 Transcription of BBS2 1 0.04 0.42 0.16
59 INT251975 Positive_regulation of Pkhd1 5 0.10 8.98 0.15
60 INT4173 Binding of Cys1 3 0.37 2.8 0.15
61 INT168523 Localization of Cdh23 2 0.22 0.27 0.15
62 INT353628 Positive_regulation of Kncn 1 0.20 0 0.15
63 INT76794 Gene_expression of AHI1 3 0.04 1.69 0.14
64 INT354535 Regulation of Negative_regulation of Pkd2 1 0.15 1.03 0.14
65 INT163225 Gene_expression of Bbs4 1 0.60 0.09 0.13
66 INT287283 Gene_expression of EZR 1 0.01 0.14 0.12
67 INT208920 Regulation of Ezr 6 0.61 2.97 0.11
68 INT325927 Phosphorylation of Ezr 1 0.82 2.74 0.09
69 INT235892 Gene_expression of Cby1 1 0.65 0 0.08
70 INT152522 Regulation of Gene_expression of Ezr 1 0.16 1.03 0.08
71 INT229283 Negative_regulation of Positive_regulation of Cby1 1 0.42 0.18 0.07
72 INT76793 Regulation of Gene_expression of AHI1 1 0.00 0.13 0.07
73 INT145889 Positive_regulation of Gene_expression of AHI1 1 0.01 0.47 0.07
74 INT353627 Positive_regulation of Gene_expression of Kncn 1 0.25 0 0.07
75 INT263071 Transcription of Kncn 2 0.34 1.06 0.06
76 INT286583 Localization of PKD2 1 0.35 0.17 0.06
77 INT261879 Binding of PKD2 3 0.13 2.59 0.05
78 INT352129 Negative_regulation of Ift88 1 0.00 0.72 0.05
79 INT340406 Regulation of Pkhd1 1 0.01 0.99 0.05
80 INT325931 Negative_regulation of Gene_expression of Ezr 1 0.58 3.57 0.04
81 INT241241 Positive_regulation of Gene_expression of Pkd2 3 0.50 1.3 0.03
82 INT325937 Positive_regulation of Ezr 1 0.50 2.17 0.03
83 INT351638 Gene_expression of Cby1 1 0.00 0.68 0.03
84 INT286581 Gene_expression of PKHD1 1 0.24 0.19 0.03
85 INT340405 Gene_expression of Pkhd1 1 0.03 1.14 0.03
86 INT286580 Positive_regulation of Gene_expression of PKHD1 1 0.16 0.1 0.03
87 INT292996 Binding of Pkhd1 3 0.07 3.12 0
88 INT241239 Regulation of Pkd2 2 0.27 0.55 0
89 INT241245 Negative_regulation of PKD2 2 0.42 2.35 0
90 INT175071 Binding of Ezr 2 0.12 0.07 0
91 INT286546 Negative_regulation of Gene_expression of Pkd2 2 0.27 0.57 0
92 INT356021 Gene_expression of MKS1 1 0.04 3.38 0
93 INT352724 Regulation of Gene_expression of Pkd2 1 0.10 0 0
94 INT235893 Negative_regulation of Cby1 1 0.42 0.42 0
95 INT291287 Positive_regulation of Positive_regulation of RPGR 1 0.45 0.13 0
96 INT268410 Positive_regulation of MKS1 1 0.03 0 0
97 INT352716 Negative_regulation of Regulation of Pkd2 1 0.15 0.08 0
98 INT268404 Regulation of MKS1 1 0.04 1.15 0
99 INT286555 Binding of Ift88 1 0.30 0.08 0
100 INT286588 Positive_regulation of Localization of PKHD1 1 0.16 0.79 0
101 INT178413 Binding of Cby1 1 0.01 0.51 0
102 INT291286 Positive_regulation of RPGR 1 0.45 0.13 0
103 INT203359 Protein_catabolism of Cdh23 1 0.09 0.52 0
104 INT286576 Binding of PKHD1 1 0.12 0.63 0
105 INT325935 Regulation of Regulation of Ezr 1 0.45 0.14 0
106 INT232493 Negative_regulation of Positive_regulation of PKD2 1 0.23 0.61 0
107 INT304591 Protein_catabolism of MKS1 1 0.86 0.49 0
108 INT177482 Negative_regulation of Negative_regulation of BBS2 1 0.03 0.73 0
109 INT268408 Transcription of MKS1 1 0.04 0.1 0
110 INT261878 Negative_regulation of Binding of PKD2 1 0.14 0.6 0
111 INT232491 Positive_regulation of PKD2 1 0.27 0.56 0
112 INT180455 Negative_regulation of Cdh23 1 0.09 0.62 0
113 INT286544 Localization of Ift88 1 0.52 1.26 0
114 INT325933 Regulation of Phosphorylation of Ezr 1 0.45 0.75 0
115 INT325932 Positive_regulation of Positive_regulation of Ezr 1 0.50 0.28 0
116 INT325936 Positive_regulation of Phosphorylation of Ezr 1 0.69 0.62 0
117 INT286584 Positive_regulation of PKHD1 1 0.13 1.01 0
118 INT286579 Localization of PKHD1 1 0.24 0.79 0
119 INT321966 Positive_regulation of EZR 1 0.45 1 0
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