GO:0005938

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Name cell cortex
Categary Component
Go Slim No
Go Link GO:0005938
Unique Molecular Interactions 728
Total Molecular Interactions 1009
Total Single Events 7522
Pain Genes Associated 114

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell cortex. They are ordered first by their pain relevance and then by number of times they were reported for cell cortex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
2 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
3 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38
4 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78
5 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
6 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
7 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34
8 INT314211 Ngf Positive_regulation of Gene_expression of Agtrap 1 0.04 1.15 1.3
9 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28
10 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
11 INT111211 Binding of Drd4 and Chdh 1 0.01 1.34 1.26
12 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24
13 INT139188 Binding of Daxx and Fas 1 0.03 0.55 1.14
14 INT1619 Binding of Gad1 and Oprl1 1 0.14 0 1.13
15 INT1620 Negative_regulation of Binding of Gad1 and Oprl1 1 0.16 0 1.13
16 INT79323 Abat Regulation of Vmn2r1 1 0.00 0 1.08
17 INT79322 Penk Regulation of Vmn2r1 1 0.00 0 1.08
18 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
19 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
20 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
21 INT122144 Binding of Trpv1 and Prkd1 1 0.02 0.39 0.96
22 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
23 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
24 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
25 INT63488 Sptan1 Positive_regulation of Rtcd1 1 0.03 0.34 0.91
26 INT167767 Prkcz Positive_regulation of Phosphorylation of Sigmar1 1 0.04 0.23 0.9
27 INT66334 Fgf2 Regulation of Fgf1 1 0.37 0.17 0.9
28 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
29 INT167766 Prkcz Positive_regulation of Positive_regulation of Sigmar1 1 0.04 0.23 0.9
30 INT52759 Oprd1 Regulation of Sptan1 1 0.03 0 0.9
31 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89
32 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
33 INT12137 Ngf Regulation of Gad1 1 0.27 0.67 0.83
34 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
35 INT190868 Binding of Marcks and Ltp 1 0.01 0.87 0.81
36 INT90381 Binding of GH1 and LAMC2 1 0.34 0.05 0.81
37 INT21233 Ngf Regulation of Fgf1 1 0.46 0.09 0.79
38 INT128180 Gna12 Regulation of Regulation of RHOA 1 0.00 0 0.78
39 INT167770 Sigmar1 Positive_regulation of Prkcz 1 0.04 0.34 0.77
40 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77
41 INT167768 Regulation of Sigmar1 Positive_regulation of Prkcz 1 0.02 0.34 0.77
42 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
43 INT4915 Binding of Tac2 and Gipc1 1 0.01 0 0.74
44 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
45 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
46 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
47 INT132696 Binding of Arc and Pag1 1 0.00 0.5 0.67
48 INT130353 spc Regulation of Fgg 1 0.02 0.2 0.66
49 INT130357 Adcy10 Regulation of Fgg 1 0.03 0.2 0.66
50 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
51 INT281083 Binding of Gria1 and Gipc1 1 0.01 0 0.65
52 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
53 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
54 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
55 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
56 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 0.05 0.05 0.59
57 INT111184 Binding of GIPC1 and CHCHD8 1 0.00 0 0.59
58 INT56700 Penk Regulation of FER 1 0.00 0 0.59
59 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
60 INT139189 Binding of Daxx and Fadd 1 0.03 0.27 0.57
61 INT77394 Binding of ARRB1 and GIPC1 1 0.01 0 0.56
62 INT253835 Binding of DST and Fos 1 0.02 0 0.55
63 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55
64 INT249717 Binding of NCL and MCF2L 1 0.23 0 0.54
65 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54
66 INT240808 Arc Regulation of Ins1 1 0.09 1.41 0.54
67 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53
68 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
69 INT103535 Obfc1 Negative_regulation of Positive_regulation of Gad1 1 0.03 0.07 0.49
70 INT172207 Binding of Drd4 and ADHD1 2 0.03 1.56 0.48
71 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
72 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
73 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
74 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
75 INT117888 Gfap Regulation of Arc 1 0.05 0.37 0.46
76 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
77 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
78 INT168699 Binding of Nedd4 and Tyr 1 0.02 0.45 0.46
79 INT117887 Glul Regulation of Arc 1 0.02 0.37 0.46
80 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
81 INT155086 CASP1 Negative_regulation of DAXX 1 0.21 1.26 0.45
82 INT13247 Binding of Arc and Helt 1 0.00 0.37 0.45
83 INT66335 Fgf1 Regulation of Fgf2 1 0.10 0.08 0.45
84 INT151958 Negative_regulation of Agt Positive_regulation of Agtrap 1 0.39 0 0.44
85 INT151959 Agt Positive_regulation of Agtrap 1 0.63 0 0.44
86 INT265137 Olah Positive_regulation of Localization of Marcks 1 0.03 0 0.42
87 INT12139 Ins1 Regulation of Gad1 1 0.15 0.33 0.42
88 INT332248 Ccl2 Positive_regulation of Ctgf 1 0.04 1.13 0.42
89 INT244421 Binding of DST and Ctss 1 0.02 0.42 0.41
90 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
91 INT160971 Gm2111 Positive_regulation of Grm7 1 0.01 0.16 0.41
92 INT205567 Regulation of Binding of Fgf1 and Chat 1 0.29 0.28 0.41
93 INT67633 Binding of DST and Gabrd 1 0.03 0 0.41
94 INT205566 Binding of Fgf1 and Chat 1 0.24 0.28 0.41
95 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4
96 INT338044 F2 Positive_regulation of Pard3 1 0.08 0.38 0.4
97 INT55588 Drd2 Regulation of Transcription of Gad1 1 0.15 0.07 0.4
98 INT55589 Drd2 Regulation of Gad1 1 0.15 0.07 0.4
99 INT346222 Positive_regulation of Braf Positive_regulation of Map2k1 1 0.15 0.67 0.39
100 INT346221 Positive_regulation of Braf Positive_regulation of Positive_regulation of Map2k2 1 0.11 0.67 0.39
101 INT346219 Positive_regulation of Braf Positive_regulation of Map2k2 1 0.11 0.67 0.39
102 INT79504 Binding of Gad1 and Chat 1 0.35 0 0.38
103 INT180442 Acot1 Positive_regulation of Rhoa 1 0.08 1.03 0.38
104 INT183645 Ppp1r14b Positive_regulation of Macf1 1 0.00 1.23 0.38
105 INT183647 Dss1 Positive_regulation of Macf1 1 0.01 1.23 0.38
106 INT183646 Negative_regulation of Ppp1r14b Positive_regulation of Macf1 1 0.00 1.29 0.38
107 INT149221 Binding of Ryr1 and Trpc3 5 0.40 0 0.37
108 INT353391 Binding of DRD4 and GRB2 1 0.37 0.62 0.37
109 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
110 INT353392 Binding of DRD4 and NCK1 1 0.37 0.62 0.37
111 INT300608 Arc Regulation of Dnm2 1 0.15 0.27 0.37
112 INT353390 Binding of DRD4 and SRC 1 0.25 0.62 0.37
113 INT245343 Prkd1 Regulation of Slc3a1 1 0.29 0.47 0.36
114 INT343912 Fgg Positive_regulation of Gene_expression of IL6 1 0.00 0.83 0.35
115 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
116 INT117589 Binding of C5AR1 and GIPC1 1 0.10 0.39 0.34
117 INT124475 MAP2K1 Positive_regulation of Positive_regulation of CPOX 1 0.04 0.68 0.33
118 INT113950 FLNA Regulation of Oprd1 1 0.00 0.16 0.32
119 INT55087 Binding of Gad1 and Penk 1 0.08 0 0.32
120 INT203089 Binding of Il1a and Traf6 1 0.04 0.66 0.32
121 INT344036 Binding of NOS1 and SPTB 1 0.01 0.31 0.32
122 INT203086 Positive_regulation of Binding of Il1a and Traf6 1 0.06 0.67 0.32
123 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31
124 INT258764 Binding of Drd4 and ADHD1 1 0.08 1.11 0.31
125 INT172822 Binding of Fga and T2dm2 1 0.01 2.24 0.31
126 INT42253 Bbx Regulation of Gad1 1 0.15 0 0.3
127 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3
128 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
129 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
130 INT244422 Binding of DST and Fig4 1 0.01 0.42 0.29
131 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
132 INT323710 TRAF6 Regulation of MIR146A 1 0.06 0.55 0.28
133 INT349951 Grm7 Regulation of pcp 1 0.00 0.56 0.28
134 INT291641 Binding of DST and ESRRG 1 0.16 1.8 0.28
135 INT240807 Arc Regulation of Gene_expression of Lepr 1 0.05 0.72 0.28
136 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
137 INT238632 Binding of EPB41 and Cask 1 0.44 0.78 0.27
138 INT231035 Arc Regulation of Gene_expression of Fos 1 0.17 0.31 0.27
139 INT262354 TRIP10 Negative_regulation of Cyp4a3 1 0.00 0.8 0.26
140 INT262353 TRIP10 Negative_regulation of Cyp1a2 1 0.03 0.8 0.26
141 INT262329 TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26
142 INT262330 Positive_regulation of TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26
143 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
144 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
145 INT60524 IFNGR2 Positive_regulation of FERMT2 1 0.04 1.87 0.25
146 INT316815 Ctgf Negative_regulation of Gene_expression of Sparc 1 0.47 0.64 0.24
147 INT193029 CHRM2 Positive_regulation of RHOA 1 0.01 0.12 0.24
148 INT140376 TGM1 Positive_regulation of Rhoa 1 0.01 0 0.24
149 INT356231 Binding of Gabrb3 and Gad1 1 0.32 1.25 0.23
150 INT269561 TMPO Positive_regulation of RHOA 1 0.22 0 0.23
151 INT122145 Prkd1 Positive_regulation of Phosphorylation of Trpv1 1 0.02 0.09 0.23
152 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
153 INT346224 Braf Negative_regulation of Phosphorylation of Map2k1 1 0.14 0.62 0.22
154 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22
155 INT180247 Binding of Gad1 and Tbca 1 0.02 0.22 0.22
156 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21
157 INT180248 Binding of Gad1 and Plp1 1 0.08 0.22 0.21
158 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
159 INT250853 Binding of Fgf1 and Mtpn 1 0.00 0.28 0.21
160 INT283373 Pcbd1 Regulation of RYR1 1 0.00 1.45 0.21
161 INT183644 Nos2 Positive_regulation of Gene_expression of Macf1 1 0.05 0.84 0.21
162 INT274080 Binding of ARHGAP4 and Map3k5 1 0.41 1.92 0.2
163 INT279964 STAT3 Regulation of Transcription of FGG 1 0.22 1.37 0.2
164 INT254687 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Mmp13 1 0.06 0.2 0.2
165 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
166 INT102743 Binding of SEPT5 and Vwf 1 0.01 0.35 0.2
167 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2
168 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
169 INT180435 Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
170 INT291642 Binding of DST and GGT1 1 0.00 1.4 0.19
171 INT180444 Positive_regulation of Acot1 Positive_regulation of Rhoa 1 0.08 0.43 0.19
172 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
173 INT153460 Inhba Positive_regulation of Gene_expression of Ctgf 1 0.77 1.14 0.19
174 INT319311 Binding of Glud1 and Ptk2b 1 0.36 0 0.19
175 INT180437 Positive_regulation of Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
176 INT153461 Tnf Positive_regulation of Gene_expression of Ctgf 1 0.48 1.13 0.19
177 INT259813 Binding of Egr1 and Arc 1 0.32 0.55 0.19
178 INT66279 Binding of FLNB and HLA-B 1 0.41 0.57 0.19
179 INT322237 Binding of Agtrap and Hcm 1 0.14 2.3 0.19
180 INT254683 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Plaur 1 0.01 0.07 0.18
181 INT254691 Gopc Positive_regulation of Positive_regulation of Map2k2 1 0.07 0.07 0.18
182 INT254698 Gopc Positive_regulation of Positive_regulation of Map2k1 1 0.06 0.07 0.18
183 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
184 INT130932 Negative_regulation of Cpox Positive_regulation of Gene_expression of TSC1 1 0.00 0.42 0.18
185 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
186 INT254685 Map2k2 Positive_regulation of Mmp3 1 0.04 0.08 0.18
187 INT338443 Binding of Gad1 and Slc32a1 1 0.31 0.64 0.18
188 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17
189 INT300305 Mapk14 Positive_regulation of Gene_expression of Ctgf 1 0.19 1.25 0.17
190 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
191 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17
192 INT220520 Ugt1a6b Positive_regulation of Gene_expression of Cav1 1 0.01 0.81 0.17
193 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
194 INT335131 PPARA Negative_regulation of Gene_expression of Fgg 1 0.01 0.59 0.17
195 INT274353 DST Regulation of Gopc 1 0.00 0 0.17
196 INT320884 Agtrap Positive_regulation of Localization of VEGFA 1 0.10 2.81 0.17
197 INT168700 Positive_regulation of Binding of Nedd4 and Tyr 1 0.03 0.19 0.17
198 INT304537 Map2k1 Positive_regulation of PRKG1 1 0.01 0.66 0.16
199 INT241967 Binding of Grm7 and Acpt 1 0.17 0 0.16
200 INT304503 Map2k1 Positive_regulation of Nos1 1 0.07 0.66 0.16

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell cortex. They are ordered first by their pain relevance and then by number of times they were reported in cell cortex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT26788 Gene_expression of Gad1 93 0.78 27.05 42.71
2 INT10453 Positive_regulation of Gad1 65 0.70 10.75 31.9
3 INT1616 Regulation of Gad1 46 0.61 10.2 28.64
4 INT4459 Positive_regulation of Arc 74 0.69 33.61 28.29
5 INT73314 Gene_expression of Arc 133 0.78 67.78 27.44
6 INT16326 Transcription of Gad1 58 0.71 15.78 20.45
7 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
8 INT22143 Gene_expression of Gad1 35 0.76 14.4 15.4
9 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
10 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09
11 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
12 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93
13 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
14 INT47702 Gene_expression of Sptan1 24 0.76 7.6 11.36
15 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
16 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
17 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55
18 INT336 Negative_regulation of Gad1 19 0.58 7.71 9.51
19 INT26789 Positive_regulation of Gene_expression of Gad1 22 0.70 7.39 9.02
20 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
21 INT73544 Gene_expression of Grm7 34 0.64 31.28 8.04
22 INT135443 Phosphorylation of Map2k1 11 0.80 2.44 8.01
23 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
24 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
25 INT135441 Positive_regulation of Map2k1 15 0.67 6.6 7.87
26 INT119940 Positive_regulation of Gene_expression of Arc 36 0.70 18.87 7.85
27 INT4457 Regulation of Arc 27 0.60 14.96 7.83
28 INT18393 Negative_regulation of Ryr1 15 0.43 3.63 7.57
29 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06
30 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
31 INT93137 Negative_regulation of Map2k1 17 0.42 4.51 6.49
32 INT118151 Positive_regulation of Prkcz 5 0.12 2.35 6.41
33 INT49011 Regulation of Gene_expression of Gad1 10 0.62 0.55 6.07
34 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
35 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
36 INT19768 Negative_regulation of LAMC2 11 0.57 10.54 5.32
37 INT135440 Positive_regulation of Phosphorylation of Map2k1 5 0.49 1.32 5.22
38 INT139162 Localization of Marcks 1 0.34 0 5.1
39 INT59555 Binding of RYR1 39 0.42 8.65 4.92
40 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81
41 INT87156 Phosphorylation of Marcks 8 0.40 2.48 4.8
42 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
43 INT66388 Positive_regulation of Transcription of Gad1 14 0.67 2.45 4.67
44 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
45 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
46 INT92682 Positive_regulation of Gene_expression of Ctgf 17 0.69 12.16 4.51
47 INT79682 Gene_expression of Grm7 6 0.75 4.74 4.5
48 INT239217 Gene_expression of Agtrap 47 0.78 48.8 4.44
49 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
50 INT39948 Binding of FLNA 45 0.42 58.05 4.27
51 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
52 INT138872 Gene_expression of SPINK5 21 0.58 30.11 4.12
53 INT88274 Positive_regulation of Drd4 7 0.69 3.48 4.1
54 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
55 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
56 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97
57 INT106065 Negative_regulation of MAP2K1 27 0.57 12.69 3.97
58 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
59 INT179391 Phosphorylation of Map2k2 1 0.02 7.01 3.89
60 INT22838 Gene_expression of Fgg 26 0.25 19.9 3.88
61 INT190858 Phosphorylation of Marcks 1 0.33 6.29 3.86
62 INT207426 Gene_expression of COL10A1 27 0.65 12.02 3.85
63 INT52755 Positive_regulation of Sptan1 6 0.67 1.57 3.82
64 INT106095 Localization of Arc 17 0.80 7.61 3.74
65 INT48143 Gene_expression of Fgf1 32 0.78 8.2 3.72
66 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
67 INT79680 Binding of Grm7 6 0.47 2.83 3.58
68 INT107555 Gene_expression of Marcks 8 0.58 1.22 3.56
69 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
70 INT102076 Regulation of DST 15 0.22 10 3.5
71 INT92681 Positive_regulation of Ctgf 13 0.69 9.78 3.47
72 INT42251 Regulation of Gad1 10 0.44 5.25 3.45
73 INT113604 Negative_regulation of Gene_expression of Ctgf 19 0.58 9.37 3.43
74 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
75 INT18396 Positive_regulation of Ryr1 10 0.58 2.45 3.38
76 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
77 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26
78 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
79 INT18394 Regulation of Ryr1 6 0.60 0.28 3.26
80 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
81 INT52756 Negative_regulation of Sptan1 7 0.42 1.31 3.19
82 INT109095 Binding of Drd4 7 0.40 3.6 3.18
83 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11
84 INT130441 Phosphorylation of MARCKS 8 0.37 3.24 3.09
85 INT92355 Negative_regulation of Marcks 4 0.48 0 3.07
86 INT81734 Regulation of Gene_expression of Arc 12 0.43 7.77 3.06
87 INT123595 Regulation of Snca 7 0.62 4.3 3.06
88 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
89 INT134470 Positive_regulation of Map2k1 74 0.49 46.07 3.02
90 INT128179 Gene_expression of RHOA 7 0.64 2.48 3.01
91 INT88273 Gene_expression of Drd4 6 0.54 1.84 3.01
92 INT67952 Regulation of Transcription of Gad1 6 0.51 1.23 2.98
93 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
94 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
95 INT639 Regulation of LAMC2 8 0.44 4.68 2.92
96 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
97 INT54170 Positive_regulation of Positive_regulation of Gad1 5 0.69 0 2.89
98 INT118156 Binding of Prkcz 2 0.08 2.68 2.89
99 INT156148 Gene_expression of CTGF 16 0.78 9.98 2.87
100 INT147412 Binding of DRD4 11 0.47 7.57 2.77
101 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
102 INT10851 Negative_regulation of Gene_expression of LAMC2 2 0.57 2.54 2.68
103 INT211733 Phosphorylation of Gipc1 2 0.01 0 2.68
104 INT209889 Gene_expression of TRAF6 13 0.63 6.85 2.67
105 INT189863 Gene_expression of DRD4 11 0.68 7.65 2.66
106 INT151037 Gene_expression of Col10a1 13 0.68 4.47 2.64
107 INT99550 Regulation of FLNA 51 0.54 27.88 2.58
108 INT82284 Negative_regulation of Gene_expression of Arc 10 0.41 4.26 2.58
109 INT179396 Positive_regulation of Map2k2 7 0.30 2.84 2.56
110 INT66002 Binding of LAMC2 9 0.47 4.5 2.54
111 INT42255 Negative_regulation of Gad1 7 0.56 4.83 2.54
112 INT46646 Localization of FLNA 19 0.73 18.83 2.53
113 INT88272 Gene_expression of Drd4 5 0.66 1.07 2.53
114 INT262339 Positive_regulation of TRIP10 2 0.26 2.07 2.5
115 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
116 INT190863 Negative_regulation of Phosphorylation of Marcks 1 0.23 4.71 2.47
117 INT54435 Binding of Sptan1 8 0.36 4.7 2.44
118 INT163544 Binding of Psen1 40 0.36 15.28 2.42
119 INT90566 Positive_regulation of Gene_expression of Gad1 5 0.48 1.46 2.42
120 INT140091 Gene_expression of Ctgf 26 0.78 14.21 2.39
121 INT128174 Positive_regulation of Gene_expression of RHOA 7 0.36 1.5 2.36
122 INT65034 Regulation of Fgf1 7 0.61 2.42 2.34
123 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
124 INT95621 Gene_expression of Gck 6 0.64 1.06 2.26
125 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
126 INT129871 Positive_regulation of Gene_expression of Gck 1 0.28 0.15 2.19
127 INT70789 Negative_regulation of Agtrap 26 0.48 16.39 2.18
128 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
129 INT67951 Negative_regulation of Gene_expression of Gad1 4 0.43 1.08 2.13
130 INT161978 Positive_regulation of Localization of GIPC1 1 0.19 1.98 2.12
131 INT664 Positive_regulation of Fgg 14 0.46 8.75 2.11
132 INT42256 Positive_regulation of Gad1 4 0.66 1.1 2.09
133 INT107554 Transcription of Marcks 1 0.59 0 2.06
134 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04
135 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
136 INT127756 Negative_regulation of Map2k1 10 0.41 6.69 2.04
137 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
138 INT54433 Transcription of Sptan1 1 0.69 0 2.03
139 INT60723 Localization of Psen2 5 0.68 2.11 2.02
140 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
141 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
142 INT44109 Localization of Gad1 7 0.74 1.06 1.97
143 INT112372 Positive_regulation of GPSM2 8 0.41 5.49 1.94
144 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
145 INT161979 Positive_regulation of Gene_expression of GIPC1 1 0.19 1.96 1.93
146 INT265157 Positive_regulation of Localization of Marcks 1 0.23 0 1.91
147 INT127125 Localization of Snca 6 0.81 8.24 1.88
148 INT109071 Positive_regulation of Phosphorylation of Marcks 2 0.20 0.48 1.88
149 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
150 INT126626 Positive_regulation of Rhoa 14 0.69 4.43 1.87
151 INT109059 Gene_expression of PRKCZ 2 0.65 0.64 1.87
152 INT118511 Gene_expression of Pard3 5 0.57 0.76 1.86
153 INT146193 Negative_regulation of Positive_regulation of Rhoa 3 0.42 3 1.84
154 INT153044 Negative_regulation of Gene_expression of Marcks 2 0.37 0 1.84
155 INT85348 Localization of RHOA 12 0.59 4.81 1.83
156 INT55587 Negative_regulation of Positive_regulation of Gad1 6 0.49 1.1 1.82
157 INT122435 Positive_regulation of Grm7 3 0.00 1.89 1.79
158 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
159 INT135444 Regulation of Map2k1 4 0.44 1.15 1.77
160 INT79683 Negative_regulation of Grm7 3 0.41 2.22 1.75
161 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
162 INT52758 Negative_regulation of Positive_regulation of Sptan1 2 0.57 0.33 1.73
163 INT257820 Positive_regulation of PAFAH1B1 1 0.68 11.09 1.69
164 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
165 INT17905 Binding of Fgg 9 0.05 4.79 1.68
166 INT254045 Gene_expression of TRIP10 4 0.29 3.04 1.67
167 INT11713 Localization of RYR1 22 0.76 10.42 1.64
168 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
169 INT181266 Gene_expression of GPSM2 18 0.32 0.54 1.64
170 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
171 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
172 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
173 INT42277 Gene_expression of GIPC1 6 0.25 2.06 1.61
174 INT179420 Positive_regulation of Phosphorylation of Map2k2 1 0.01 2.17 1.58
175 INT154687 Negative_regulation of Fga 1 0.11 1.09 1.58
176 INT4458 Positive_regulation of Positive_regulation of Arc 5 0.49 2.19 1.55
177 INT138083 Positive_regulation of Gene_expression of Drd4 2 0.40 1.34 1.55
178 INT118149 Positive_regulation of Binding of Prkcz 1 0.09 0.58 1.54
179 INT153045 Negative_regulation of Negative_regulation of Marcks 1 0.37 0 1.54
180 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
181 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
182 INT72329 Transcription of Arc 20 0.67 12.52 1.51
183 INT146190 Negative_regulation of Localization of Rhoa 4 0.42 1.64 1.5
184 INT73816 Positive_regulation of Fgf1 5 0.70 2.31 1.49
185 INT111186 Positive_regulation of GIPC1 4 0.67 1.44 1.46
186 INT201271 Phosphorylation of Snca 3 0.82 4.22 1.45
187 INT92685 Transcription of Ctgf 7 0.72 3.92 1.44
188 INT254072 Gene_expression of SEPT5 23 0.16 8.29 1.43
189 INT103531 Regulation of Positive_regulation of Gad1 3 0.61 0.31 1.43
190 INT78646 Regulation of Psen2 4 0.20 1.78 1.42
191 INT118150 Positive_regulation of Positive_regulation of Prkcz 1 0.08 0.49 1.42
192 INT104121 Positive_regulation of MAP2K1 8 0.61 4.84 1.41
193 INT63328 Binding of Fgf1 10 0.37 1.5 1.4
194 INT124247 Negative_regulation of Gene_expression of Snca 12 0.59 3.87 1.39
195 INT175525 Positive_regulation of Phosphorylation of Map2k1 8 0.33 7.02 1.37
196 INT71782 Gene_expression of MAP2K1 7 0.68 3.17 1.37
197 INT90567 Negative_regulation of Gene_expression of Gad1 4 0.41 2.88 1.36
198 INT96641 Transcription of Gad1 3 0.60 0.84 1.36
199 INT254666 Positive_regulation of Map2k2 37 0.56 23.85 1.35
200 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
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