GO:0006084

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Name acetyl-CoA metabolic process
Categary Process
Go Slim No
Go Link GO:0006084
Unique Molecular Interactions 31
Total Molecular Interactions 45
Total Single Events 195
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for acetyl-CoA metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for acetyl-CoA metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125574 CS Regulation of Ldha 1 0.02 0.23 0.42
2 INT272052 Binding of CS and Cfcd 1 0.00 0.54 0.4
3 INT127156 HSD17B10 Regulation of Acaa2 1 0.02 0 0.12
4 INT244452 CS Positive_regulation of Phosphorylation of EIF2S2 1 0.21 2.07 0.09
5 INT244449 CS Regulation of Gene_expression of ATF4 1 0.15 0.83 0.08
6 INT244461 CS Positive_regulation of ESR1 1 0.06 1.15 0.05
7 INT204172 Regulation of Binding of Cs and Nox1 1 0.08 1.01 0.04
8 INT204173 Binding of Cs and Nox1 1 0.07 1 0.04
9 INT313618 Binding of Acly and Pdgfb 1 0.00 0.18 0.03
10 INT244474 CS Regulation of XBP1 1 0.20 0.15 0
11 INT244480 CS Negative_regulation of Gene_expression of XBP1 1 0.16 0.11 0
12 INT244476 CS Positive_regulation of ATF3 1 0.13 0.13 0
13 INT64385 Cs Negative_regulation of PGC 1 0.00 0.15 0
14 INT244469 CS Positive_regulation of PPP1R15A 1 0.08 0.12 0
15 INT317769 Binding of Nfe2l2 and Acly 1 0.22 0.08 0
16 INT329215 Prkag1 Negative_regulation of Acaca 1 0.08 0.26 0
17 INT244457 CS Positive_regulation of Gene_expression of ESR1 1 0.07 0.67 0
18 INT244458 CS Positive_regulation of ERN1 1 0.17 0.71 0
19 INT244475 Binding of CS and Positive_regulation of EIF2S2 1 0.11 0.07 0
20 INT317768 Nfe2l2 Regulation of Acly 1 0.38 0.25 0
21 INT244477 CS Regulation of Gene_expression of ATF6 1 0.18 0.07 0
22 INT244453 CS Positive_regulation of Gene_expression of TMBIM6 1 0.07 1.3 0
23 INT244479 CS Positive_regulation of ATF6 1 0.17 1.02 0
24 INT244460 Binding of CS and Positive_regulation of Positive_regulation of EIF2S2 1 0.13 0.06 0
25 INT244468 CS Positive_regulation of EIF2S2 1 0.16 0.43 0
26 INT244467 Negative_regulation of CS Positive_regulation of EIF2S2 1 0.11 0.14 0
27 INT244478 Regulation of CS Regulation of XBP1 1 0.20 0.06 0
28 INT244482 CS Positive_regulation of Transcription of ATF3 1 0.13 0.13 0
29 INT244472 CS Negative_regulation of Binding of XBP1 1 0.19 1.07 0
30 INT295616 ACACB Regulation of INS 1 0.02 0.6 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for acetyl-CoA metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in acetyl-CoA metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT26363 Negative_regulation of CS 8 0.26 2.49 2.36
2 INT26364 Positive_regulation of CS 12 0.30 4.99 1.89
3 INT125573 Gene_expression of CS 26 0.41 8 0.98
4 INT9368 Regulation of CS 6 0.17 1.67 0.8
5 INT111199 Gene_expression of Acly 11 0.16 5.65 0.78
6 INT205905 Gene_expression of Acly 4 0.59 0.37 0.59
7 INT316558 Positive_regulation of ACACB 1 0.21 2.66 0.42
8 INT205274 Gene_expression of Cs 2 0.75 2.08 0.36
9 INT205897 Positive_regulation of Gene_expression of Acly 1 0.53 0.09 0.36
10 INT316557 Regulation of ACACB 1 0.14 3.3 0.29
11 INT145256 Binding of Acly 2 0.07 1.17 0.27
12 INT205532 Binding of CS 7 0.14 1.27 0.22
13 INT145257 Positive_regulation of Acly 1 0.03 1.39 0.18
14 INT244569 Phosphorylation of CS 1 0.31 2.96 0.15
15 INT244487 Regulation of Positive_regulation of CS 1 0.10 0.18 0.12
16 INT295619 Localization of ACACB 2 0.65 1.79 0.11
17 INT273675 Binding of ACACB 7 0.42 8.69 0.09
18 INT244553 Positive_regulation of Gene_expression of CS 6 0.22 3.07 0.09
19 INT336476 Positive_regulation of Binding of CS 1 0.09 0 0.09
20 INT329390 Negative_regulation of Gene_expression of Acly 1 0.10 0.83 0.09
21 INT310273 Negative_regulation of Acaca 1 0.19 1.08 0.07
22 INT127152 Negative_regulation of Acaa2 1 0.22 0.52 0.07
23 INT205533 Localization of CS 4 0.28 0.69 0.06
24 INT329391 Positive_regulation of Gene_expression of Acly 1 0.12 0.68 0.06
25 INT205887 Positive_regulation of Acly 1 0.31 0.37 0.06
26 INT244536 Negative_regulation of Gene_expression of CS 3 0.31 0.88 0.04
27 INT204165 Regulation of Cs 2 0.09 1.35 0.04
28 INT244518 Positive_regulation of Localization of CS 2 0.19 0.37 0.03
29 INT273677 Gene_expression of ACACB 15 0.67 9.36 0
30 INT192069 Localization of Acly 1 0.02 0.84 0
31 INT244530 Regulation of Binding of CS 1 0.17 0.06 0
32 INT295618 Positive_regulation of Gene_expression of ACACB 1 0.43 0.68 0
33 INT317762 Localization of Acly 1 0.40 0.12 0
34 INT301553 Positive_regulation of Acaca 1 0.18 0.45 0
35 INT317760 Binding of Acly 1 0.19 0.08 0
36 INT301545 Protein_catabolism of Acaca 1 0.20 0.44 0
37 INT329392 Negative_regulation of Acly 1 0.10 0.47 0
38 INT344633 Negative_regulation of Cs 1 0.42 0.82 0
39 INT244565 Negative_regulation of Phosphorylation of CS 1 0.16 0.24 0
40 INT192070 Positive_regulation of Localization of Acly 1 0.02 0.84 0
41 INT308737 Phosphorylation of Acaca 1 0.08 0 0
42 INT244515 Regulation of Gene_expression of CS 1 0.20 1.26 0
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