GO:0006098

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Name pentose-phosphate shunt
Categary Process
Go Slim No
Go Link GO:0006098
Unique Molecular Interactions 58
Total Molecular Interactions 74
Total Single Events 1087
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for pentose-phosphate shunt. They are ordered first by their pain relevance and then by number of times they were reported for pentose-phosphate shunt. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT31776 Positive_regulation of Gclc Positive_regulation of G6pd 1 0.29 0.19 0.75
2 INT288323 Glyr1 Regulation of Sds 1 0.05 0.2 0.72
3 INT288326 Sds Positive_regulation of Glyr1 1 0.10 0.12 0.68
4 INT288324 Sds Positive_regulation of Gene_expression of Glyr1 1 0.10 0.12 0.68
5 INT309370 Positive_regulation of Glyr1 Positive_regulation of Positive_regulation of Gphn 1 0.01 0 0.47
6 INT13548 Binding of PDYN and TALDO1 1 0.40 0 0.35
7 INT46788 Chrna7 Positive_regulation of G6pd 1 0.50 0 0.33
8 INT109901 RPE Positive_regulation of Positive_regulation of MAP3K14 1 0.54 0.15 0.33
9 INT109902 RPE Positive_regulation of Gene_expression of CCL16 1 0.07 0.15 0.33
10 INT288325 Binding of Glyr1 and Sds 1 0.07 0 0.3
11 INT156661 Binding of Pgls and Sdhb 1 0.01 1.43 0.25
12 INT263366 Dlat Regulation of Glyr1 1 0.03 0 0.22
13 INT161746 Binding of G6PD and HBG2 1 0.21 0.36 0.19
14 INT263365 Glyr1 Regulation of Dlat 1 0.03 0.18 0.17
15 INT252575 Rpe Negative_regulation of SOD1 1 0.03 2.39 0.14
16 INT252571 Rpe Positive_regulation of Positive_regulation of Sdcbp 1 0.04 2.27 0.13
17 INT252573 Rpe Negative_regulation of Gpx1 1 0.07 2.34 0.13
18 INT315829 Binding of EGFR and TKT 1 0.03 1.14 0.12
19 INT161747 Positive_regulation of Binding of G6PD and HBG2 1 0.28 0.18 0.1
20 INT349340 SRI Regulation of Rpe 1 0.02 0.05 0.09
21 INT252572 Rpe Positive_regulation of Sdcbp 1 0.04 1.12 0.09
22 INT339583 Binding of ABCA1 and RPE 1 0.03 1.38 0.05
23 INT339587 Positive_regulation of Binding of ABCA1 and RPE 1 0.04 1.38 0.05
24 INT349339 Rpe Regulation of Per2 1 0.30 0 0.04
25 INT349338 Regulation of Rpe Regulation of Gene_expression of Per2 1 0.21 0.06 0.03
26 INT262617 Ager Positive_regulation of Rpe 1 0.00 0.81 0
27 INT235596 HNF4A Regulation of Gene_expression of TPI1 1 0.00 0.25 0
28 INT256982 Binding of Cd81 and Rpe 1 0.13 0 0
29 INT256988 Binding of Dlg1 and Rpe 1 0.06 0 0
30 INT330048 G6pd Positive_regulation of Gene_expression of Ros1 1 0.03 0.61 0
31 INT262750 GLYR1 Positive_regulation of THBS1 1 0.01 0.99 0
32 INT290104 Myo7a Regulation of RPE 1 0.03 0.75 0
33 INT290046 RAB27A Regulation of RPE 1 0.03 0.75 0
34 INT243120 Binding of amd and Rpe 1 0.26 1.18 0
35 INT256980 Binding of Slc9a3r1 and Rpe 1 0.08 0.13 0
36 INT277896 EGF Positive_regulation of TKT 1 0.02 0.76 0
37 INT243118 amd Regulation of Rpe 1 0.20 1.16 0
38 INT339586 TIMP3 Positive_regulation of RPE 1 0.16 0.72 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for pentose-phosphate shunt. They are ordered first by their pain relevance and then by number of times they were reported in pentose-phosphate shunt. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85
2 INT5409 Negative_regulation of G6pd 33 0.57 29.21 7.64
3 INT112873 Gene_expression of Glyr1 28 0.76 2.88 5.94
4 INT5411 Positive_regulation of G6pd 20 0.70 4.74 5.11
5 INT112872 Negative_regulation of Glyr1 9 0.42 2.4 3.59
6 INT65072 Gene_expression of TKT 16 0.65 17.58 3.55
7 INT164087 Gene_expression of TPI1 42 0.78 5.39 3.21
8 INT5412 Regulation of G6pd 9 0.62 1.64 2.87
9 INT105532 Positive_regulation of Glyr1 2 0.34 1.29 2.36
10 INT5998 Negative_regulation of Glyr1 4 0.32 0.47 2.2
11 INT164085 Positive_regulation of Gene_expression of TPI1 4 0.60 0.06 2.09
12 INT117799 Positive_regulation of Glyr1 4 0.46 0.42 1.98
13 INT105531 Positive_regulation of Positive_regulation of Glyr1 2 0.31 0.74 1.6
14 INT46786 Positive_regulation of Positive_regulation of G6pd 3 0.47 0.47 1.52
15 INT14048 Negative_regulation of TKT 13 0.34 5.05 1.51
16 INT5997 Regulation of Glyr1 3 0.38 0.34 1.38
17 INT5410 Gene_expression of G6pd 15 0.75 4.59 1.28
18 INT72997 Negative_regulation of GLYR1 2 0.41 1.03 1.2
19 INT36451 Gene_expression of G6PD 26 0.75 7.2 1.09
20 INT143208 Negative_regulation of TPI1 30 0.59 7.54 1.08
21 INT5999 Gene_expression of Glyr1 2 0.20 0.74 1.08
22 INT288317 Positive_regulation of Gene_expression of Glyr1 2 0.13 0.36 0.9
23 INT341863 Negative_regulation of Localization of RPE 1 0.03 7.39 0.9
24 INT309353 Positive_regulation of Positive_regulation of Glyr1 1 0.03 0 0.9
25 INT105530 Regulation of Negative_regulation of Glyr1 1 0.28 0.06 0.85
26 INT51262 Positive_regulation of TKT 7 0.69 4.31 0.82
27 INT4103 Regulation of G6PD 6 0.60 0.78 0.82
28 INT17855 Binding of G6pd 4 0.34 1.42 0.8
29 INT251224 Negative_regulation of Gene_expression of Glyr1 3 0.12 0.17 0.75
30 INT152523 Gene_expression of Rpe 5 0.56 2.55 0.74
31 INT137555 Regulation of GLYR1 2 0.37 0.69 0.73
32 INT72995 Gene_expression of GLYR1 2 0.75 0.16 0.71
33 INT164089 Positive_regulation of Transcription of TPI1 1 0.43 0 0.71
34 INT164088 Positive_regulation of TPI1 8 0.50 1.26 0.7
35 INT164090 Transcription of TPI1 2 0.71 0.08 0.7
36 INT109925 Gene_expression of RPE 11 0.65 12.46 0.68
37 INT143207 Binding of TPI1 9 0.42 0.65 0.64
38 INT213410 Localization of TKT 3 0.71 1.89 0.61
39 INT200754 Gene_expression of Rpe 35 0.51 6.3 0.58
40 INT106246 Positive_regulation of GLYR1 2 0.23 0.29 0.57
41 INT109904 Localization of RPE 5 0.73 4.9 0.56
42 INT118549 Negative_regulation of Phosphorylation of Glyr1 1 0.32 0.35 0.54
43 INT118550 Phosphorylation of Glyr1 1 0.61 0.35 0.53
44 INT150503 Regulation of Negative_regulation of TKT 1 0.18 0 0.52
45 INT309344 Regulation of Glyr1 2 0.13 0.36 0.51
46 INT309340 Negative_regulation of Negative_regulation of Glyr1 1 0.03 0.47 0.49
47 INT309336 Localization of Glyr1 1 0.05 0.09 0.48
48 INT109903 Positive_regulation of Gene_expression of RPE 3 0.49 0.59 0.46
49 INT36450 Regulation of Negative_regulation of G6PD 2 0.40 1.59 0.46
50 INT4553 Binding of G6PD 7 0.37 3 0.44
51 INT31603 Regulation of Gene_expression of G6pd 1 0.59 0 0.43
52 INT161027 Negative_regulation of RPE 7 0.37 4.34 0.38
53 INT46787 Regulation of Regulation of G6pd 1 0.24 0 0.36
54 INT156655 Positive_regulation of Pgls 2 0.38 3.11 0.35
55 INT139779 Negative_regulation of Negative_regulation of G6PD 1 0.42 0.29 0.35
56 INT309356 Binding of Glyr1 1 0.02 0.36 0.34
57 INT228433 Negative_regulation of Gene_expression of TKT 2 0.35 1.13 0.32
58 INT137905 Regulation of TKT 2 0.13 1.05 0.32
59 INT80664 Phosphorylation of G6PD 3 0.08 0.58 0.3
60 INT210228 Positive_regulation of Rpe 15 0.52 8.78 0.26
61 INT263352 Positive_regulation of Gene_expression of Glyr1 1 0.07 0 0.26
62 INT72996 Binding of GLYR1 2 0.03 0 0.25
63 INT263357 Regulation of Gene_expression of Glyr1 1 0.04 0 0.22
64 INT175220 Binding of TKT 3 0.25 1.21 0.19
65 INT118575 Positive_regulation of G6PD 9 0.50 3.35 0.18
66 INT149764 Negative_regulation of Rpe 3 0.49 2.07 0.16
67 INT252569 Positive_regulation of Rpe 8 0.38 1.26 0.15
68 INT109930 Positive_regulation of RPE 4 0.49 5.88 0.15
69 INT349337 Transcription of Rpe 1 0.45 0.08 0.15
70 INT65071 Positive_regulation of Gene_expression of TKT 4 0.18 4.44 0.14
71 INT260172 Localization of Rpe 11 0.49 3.53 0.12
72 INT109934 Positive_regulation of Localization of RPE 1 0.49 0.09 0.12
73 INT349336 Regulation of Transcription of Rpe 1 0.30 0.08 0.12
74 INT288311 Transcription of Glyr1 1 0.14 0 0.11
75 INT243112 Regulation of Rpe 5 0.40 3.14 0.1
76 INT118574 Positive_regulation of Gene_expression of G6PD 2 0.49 0.33 0.1
77 INT309349 Regulation of Binding of Glyr1 1 0.02 0.28 0.1
78 INT268715 Binding of RPE 3 0.09 2.36 0.09
79 INT213412 Phosphorylation of TKT 3 0.13 1.94 0.09
80 INT144322 Regulation of RPE 1 0.24 1.9 0.08
81 INT329916 Localization of Pgls 1 0.61 1.33 0.07
82 INT288315 Regulation of Gene_expression of Glyr1 1 0.12 0 0.06
83 INT320587 Localization of Glyr1 1 0.07 0.2 0.06
84 INT256957 Positive_regulation of Gene_expression of Rpe 2 0.28 0 0.04
85 INT329915 Gene_expression of Pgls 1 0.51 1.21 0.04
86 INT200759 Positive_regulation of Gene_expression of Rpe 5 0.21 0.88 0.03
87 INT174190 Regulation of Gene_expression of TKT 4 0.43 2.99 0.03
88 INT172456 Negative_regulation of Rpe 2 0.32 1.18 0.03
89 INT256963 Binding of Rpe 2 0.27 0.06 0.03
90 INT229428 Localization of G6pd 2 0.73 0 0.03
91 INT297433 Phosphorylation of G6pd 1 0.06 0.12 0.03
92 INT252570 Regulation of Rpe 1 0.33 0.88 0.03
93 INT349335 Regulation of Regulation of Rpe 1 0.40 0 0.03
94 INT200712 Regulation of TPI1 8 0.62 1.64 0
95 INT234281 Binding of Rpe 5 0.10 2.03 0
96 INT262586 Regulation of Binding of Rpe 2 0.09 1.9 0
97 INT203778 Regulation of Gene_expression of G6PD 1 0.20 0 0
98 INT200708 Localization of TPI1 1 0.65 0.08 0
99 INT304334 Positive_regulation of Positive_regulation of Rpe 1 0.28 0 0
100 INT210227 Regulation of Positive_regulation of Rpe 1 0.19 0.74 0
101 INT291149 Positive_regulation of Positive_regulation of G6PD 1 0.04 0 0
102 INT200705 Negative_regulation of Transcription of TPI1 1 0.58 0.08 0
103 INT200707 Positive_regulation of Negative_regulation of TPI1 1 0.40 0.07 0
104 INT189275 Transcription of G6PD 1 0.68 0.06 0
105 INT239792 Regulation of Localization of RPE 1 0.15 0.17 0
106 INT203777 Negative_regulation of Gene_expression of G6PD 1 0.14 0 0
107 INT200709 Positive_regulation of Positive_regulation of TPI1 1 0.50 0.4 0
108 INT185701 Negative_regulation of Gene_expression of G6pd 1 0.12 0.23 0
109 INT200706 Regulation of Negative_regulation of TPI1 1 0.39 0.15 0
110 INT200703 Negative_regulation of Binding of TPI1 1 0.42 0.07 0
111 INT262890 Positive_regulation of Transcription of TALDO1 1 0.09 0 0
112 INT200704 Negative_regulation of Gene_expression of TPI1 1 0.51 0.07 0
113 INT235597 Regulation of Gene_expression of TPI1 1 0.45 0.25 0
114 INT290088 Protein_catabolism of RPE 1 0.07 1.06 0
115 INT200711 Protein_catabolism of TPI1 1 0.57 0 0
116 INT277666 Negative_regulation of Positive_regulation of TKT 1 0.08 0.5 0
117 INT262889 Transcription of TALDO1 1 0.12 0.12 0
118 INT277903 Positive_regulation of Phosphorylation of TKT 1 0.05 0.83 0
119 INT349334 Positive_regulation of Localization of Rpe 1 0.33 0 0
120 INT229780 Localization of G6PD 1 0.16 0.67 0
121 INT267539 Regulation of Gene_expression of Rpe 1 0.06 0.19 0
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