GO:0006184

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Name GTP catabolic process
Categary Process
Go Slim No
Go Link GO:0006184
Unique Molecular Interactions 775
Total Molecular Interactions 1099
Total Single Events 6812
Pain Genes Associated 83

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for GTP catabolic process. They are ordered first by their pain relevance and then by number of times they were reported for GTP catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6
2 INT269444 Binding of RAB5A and HHIP 1 0.04 0 5.79
3 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18
4 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89
5 INT96465 Pnoc Positive_regulation of GEM 1 0.01 0.74 2.39
6 INT133946 Binding of DNM2 and OPRK1 1 0.11 0 2.1
7 INT13940 DNM2 Regulation of Localization of CGA 1 0.11 0 1.86
8 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
9 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67
10 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65
11 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65
12 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64
13 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54
14 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5
15 INT21425 Binding of Pomc and Gtpbp4 1 0.01 0.1 1.45
16 INT133933 Binding of DNM2 and TP53INP2 1 0.00 0 1.38
17 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
18 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
19 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
20 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
21 INT21424 Binding of Penk and Gtpbp4 1 0.02 0.16 1.2
22 INT65203 OPRL1 Negative_regulation of ADCY1 1 0.19 0 1.19
23 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
24 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19
25 INT264930 Gnaz Positive_regulation of Negative_regulation of Cnr1 1 0.20 0 1.14
26 INT65204 PNOC Negative_regulation of ADCY1 1 0.07 0 1.14
27 INT117504 OPA1 Positive_regulation of CPP 1 0.09 1.09 1.13
28 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
29 INT264931 Binding of Gnaz and Hrh1 1 0.01 0.83 1.12
30 INT64259 Binding of Gtpbp4 and Ptprg 1 0.06 0 1.1
31 INT269443 Positive_regulation of Binding of RAB5A and HHIP 1 0.04 0 1.06
32 INT18828 DNM2 Positive_regulation of Localization of LTB4R 1 0.01 0.07 1.06
33 INT118859 GNA14 Positive_regulation of STAT3 1 0.01 0.38 1.03
34 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 0.02 0.3 1.02
35 INT53052 ANTXRL Negative_regulation of Negative_regulation of ADCY1 1 0.01 0.66 0.99
36 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99
37 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 0.21 0.98 0.95
38 INT264926 Binding of Gnaz and Pag1 1 0.08 0.19 0.94
39 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
40 INT52114 Oprd1 Regulation of ADCY1 2 0.05 0.46 0.9
41 INT54200 Gnai1 Negative_regulation of Pag1 1 0.05 0.18 0.9
42 INT54197 Binding of Gnai1 and Pag1 1 0.04 0.18 0.9
43 INT53152 Rac1 Regulation of Scg2 1 0.03 0 0.9
44 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
45 INT301079 Binding of GNAT1 and INPP5E 1 0.00 0.59 0.89
46 INT52390 OPRD1 Regulation of ADCY1 1 0.09 0.13 0.86
47 INT114324 RAF1 Positive_regulation of Phosphorylation of ADCY6 1 0.02 0.05 0.85
48 INT124878 Gnat3 Negative_regulation of Gene_expression of FOS 1 0.09 0.16 0.85
49 INT114323 Binding of ADCY6 and RAF1 1 0.02 0.05 0.85
50 INT80877 Negative_regulation of PCDHB17 Negative_regulation of ADCY1 1 0.01 0.08 0.84
51 INT80878 PCDHB17 Negative_regulation of ADCY1 1 0.01 0.08 0.84
52 INT74383 Sst Positive_regulation of GEM 1 0.01 0.09 0.82
53 INT269455 Binding of RAB5A and GOPC 1 0.08 0 0.82
54 INT74382 Negative_regulation of Sst Positive_regulation of GEM 1 0.00 0.09 0.82
55 INT124877 Gnat3 Negative_regulation of FOS 1 0.09 0.15 0.82
56 INT124876 Gnat3 Negative_regulation of Positive_regulation of FOS 1 0.09 0.15 0.82
57 INT74384 Regulation of Sst Positive_regulation of GEM 1 0.00 0.09 0.82
58 INT128180 Gna12 Regulation of Regulation of RHOA 1 0.00 0 0.78
59 INT142454 Npff Positive_regulation of Gtpbp4 1 0.56 0 0.78
60 INT142455 Binding of Npff and Gtpbp4 1 0.40 0 0.78
61 INT81976 Binding of GNA15 and OPRL1 1 0.02 0 0.77
62 INT118854 GNA14 Positive_regulation of Positive_regulation of STAT3 1 0.02 0.31 0.76
63 INT133935 DNM2 Positive_regulation of OPRK1 1 0.11 0 0.76
64 INT65593 CALCA Negative_regulation of Positive_regulation of ADCY1 1 0.23 0.07 0.76
65 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
66 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
67 INT148909 Binding of GNA13 and TP53INP2 1 0.06 0.31 0.73
68 INT133943 Binding of DNM2 and OPRL1 1 0.00 0 0.73
69 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72
70 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
71 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
72 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
73 INT123869 Binding of GNAS and OPRK1 1 0.00 0.37 0.7
74 INT133936 Binding of DNM2 and YY1 1 0.29 0 0.69
75 INT74599 YY1 Negative_regulation of ADCY1 2 0.36 0.31 0.67
76 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
77 INT113931 Mors1 Positive_regulation of Gtpbp4 1 0.02 0 0.67
78 INT264927 Cnr1 Regulation of Gnaz 1 0.23 0.05 0.66
79 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 0.03 0.24 0.65
80 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
81 INT34211 DNM2 Regulation of Localization of Crh 1 0.01 0.09 0.63
82 INT334594 Binding of GNAI1 and MRGPRD 1 0.01 0.19 0.63
83 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
84 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
85 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 0.05 0.05 0.59
86 INT161387 Binding of PNOC and GTPBP4 1 0.03 1.05 0.59
87 INT210830 OPRM1 Negative_regulation of ADCY1 1 0.00 0.06 0.55
88 INT59635 Binding of Adarb1 and Gnaz 1 0.01 0 0.55
89 INT32908 Binding of ADCY1 and Drd2 1 0.00 0 0.54
90 INT64744 OR5D2P Negative_regulation of ADCY1 1 0.00 0 0.54
91 INT164971 Binding of Rgs7 and Gnai2 1 0.01 0 0.54
92 INT269449 Positive_regulation of Binding of RAB5A and GOPC 1 0.11 0 0.53
93 INT164970 Binding of Rgs8 and Gnai2 1 0.01 0 0.53
94 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
95 INT77218 Binding of NFKBIL1 and NKIRAS2 1 0.00 0.27 0.51
96 INT93265 Binding of ADCY1 and OPRL1 1 0.13 0.17 0.51
97 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
98 INT81004 Htr1a Positive_regulation of Gtpbp4 1 0.20 0 0.5
99 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 1 0.42 0.21 0.48
100 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 1 0.38 0.21 0.48
101 INT89647 OPRM1 Regulation of ADCY1 1 0.09 0.09 0.47
102 INT153658 PRKCA Negative_regulation of GEM 1 0.01 0.22 0.46
103 INT258584 ADORA3 Negative_regulation of ADCY1 1 0.02 0 0.44
104 INT111275 BRI3P1 Positive_regulation of Negative_regulation of ADCY1 1 0.06 0 0.44
105 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
106 INT89649 INSRR Regulation of ADCY1 1 0.00 0.07 0.44
107 INT111274 C2 Positive_regulation of Negative_regulation of ADCY1 1 0.14 0 0.44
108 INT72016 Positive_regulation of Binding of Gnai2 and Ptprg 1 0.02 0 0.44
109 INT73832 Pld1 Positive_regulation of ADCY1 1 0.00 0.16 0.44
110 INT251430 Gnat3 Positive_regulation of Gucy1b2 1 0.04 0.48 0.42
111 INT346218 Positive_regulation of Kras Positive_regulation of Phosphorylation of Mdk 1 0.01 0.71 0.42
112 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
113 INT269448 HHIP Positive_regulation of Binding of RAB5A 1 0.04 0 0.42
114 INT131505 Rac1 Regulation of Gene_expression of Trpv1 1 0.55 0.39 0.42
115 INT68526 Binding of ADCY1 and DIO2 1 0.01 0.07 0.41
116 INT80233 Positive_regulation of OPRM1 Positive_regulation of GNAI1 1 0.23 0 0.41
117 INT72018 Binding of Gnai2 and Ptprg 1 0.01 0 0.41
118 INT68527 Binding of ADCY1 and OPRD1 1 0.06 0.07 0.41
119 INT105170 OPRD1 Positive_regulation of Phosphorylation of ADCY1 1 0.08 0 0.41
120 INT80232 OPRM1 Positive_regulation of GNAI1 1 0.23 0 0.41
121 INT11425 OR2A12 Positive_regulation of Negative_regulation of ADCY1 1 0.01 0 0.4
122 INT105169 RAF1 Regulation of Positive_regulation of ADCY1 1 0.12 0 0.4
123 INT124799 PRKCA Positive_regulation of Localization of ADCY6 1 0.19 0 0.4
124 INT56876 Regulation of Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
125 INT56875 Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
126 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
127 INT269456 RAB5A Regulation of Binding of HHIP 1 0.04 0 0.38
128 INT180442 Acot1 Positive_regulation of Rhoa 1 0.08 1.03 0.38
129 INT300610 Rorb Regulation of Dnm2 1 0.01 0.27 0.37
130 INT300608 Arc Regulation of Dnm2 1 0.15 0.27 0.37
131 INT173356 Gnaq Positive_regulation of CDK20 1 0.06 0 0.37
132 INT251426 Gnat3 Negative_regulation of Aldh2 1 0.22 0 0.35
133 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
134 INT134080 OPA1 Negative_regulation of Phosphorylation of Gnb2l1 1 0.03 0.22 0.34
135 INT88252 Binding of RAP1A and Krit1 1 0.36 2.25 0.33
136 INT109282 Gdi2 Negative_regulation of Gtpbp4 1 0.01 0.13 0.32
137 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
138 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32
139 INT295722 PTGER2 Positive_regulation of RAC1 1 0.02 2.14 0.32
140 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
141 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 0.02 0.21 0.32
142 INT295725 PTGER2 Positive_regulation of RAC2 1 0.05 1.92 0.32
143 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
144 INT152061 Binding of SEPT9 and CD177 1 0.00 1.76 0.31
145 INT303105 CAMK4 Positive_regulation of Hras1 1 0.04 0.16 0.31
146 INT169612 OGFR Regulation of RAN 1 0.23 0.14 0.3
147 INT260438 Binding of Cd4 and Mx1 1 0.00 1.52 0.29
148 INT260434 Binding of Cd8a and Mx1 1 0.00 1.52 0.29
149 INT339001 GSX1 Positive_regulation of ADCY1 1 0.01 0 0.29
150 INT141438 Gnai2 Positive_regulation of Localization of ADCY1 1 0.01 0.43 0.29
151 INT251420 Aldh3a1 Regulation of Gene_expression of Gnat3 1 0.09 0.08 0.28
152 INT71550 GTPBP4 Regulation of Localization of INS 1 0.00 0.16 0.28
153 INT346220 Binding of Kras and Braf 1 0.03 0.58 0.28
154 INT64892 ANTXR1 Regulation of Gtpbp4 1 0.00 0.47 0.28
155 INT174311 Binding of Krit1 and Rap1a 1 0.04 1.08 0.28
156 INT210828 POMC Positive_regulation of ADCY1 1 0.03 0.34 0.28
157 INT118852 Positive_regulation of GNA14 Positive_regulation of CAMK2G 1 0.01 0.09 0.27
158 INT265831 BGN Positive_regulation of ADCY1 1 0.01 0.41 0.27
159 INT118855 Binding of SRC and GNA14 1 0.01 0.13 0.27
160 INT229785 Binding of RAB7A and SPTLC1 1 0.40 1.5 0.27
161 INT118846 GNA14 Positive_regulation of CAMK2G 1 0.01 0.09 0.27
162 INT93952 CGA Positive_regulation of ADCY1 1 0.03 0 0.27
163 INT215279 Siglec1 Regulation of Rac2 1 0.01 0.74 0.27
164 INT93953 Negative_regulation of CGA Positive_regulation of ADCY1 1 0.03 0 0.27
165 INT118848 GNA14 Positive_regulation of RAC1 1 0.01 0.14 0.26
166 INT118856 Positive_regulation of GNA14 Positive_regulation of STAT3 1 0.01 0.14 0.26
167 INT118849 GNA14 Positive_regulation of MAPK1 1 0.00 0.14 0.26
168 INT118851 GNA14 Positive_regulation of RAF1 1 0.00 0.14 0.26
169 INT223042 AR Positive_regulation of ADCY1 1 0.01 0.41 0.25
170 INT223036 SLURP1 Regulation of Positive_regulation of ADCY1 1 0.00 0.42 0.25
171 INT193029 CHRM2 Positive_regulation of RHOA 1 0.01 0.12 0.24
172 INT140376 TGM1 Positive_regulation of Rhoa 1 0.01 0 0.24
173 INT269561 TMPO Positive_regulation of RHOA 1 0.22 0 0.23
174 INT292561 MAP3K5 Positive_regulation of Positive_regulation of RAC1 1 0.03 0 0.23
175 INT34499 ADRB3 Positive_regulation of ADCY1 1 0.07 0.19 0.23
176 INT118850 GNA14 Positive_regulation of Phosphorylation of SRC 1 0.02 0.15 0.23
177 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
178 INT173358 Gnaq Positive_regulation of SMPD1 1 0.01 0.13 0.23
179 INT169611 Binding of RAN and OGFR 1 0.24 0.19 0.23
180 INT298876 RAB7A Positive_regulation of Protein_catabolism of NTRK1 1 0.14 0.44 0.22
181 INT354544 Avp Positive_regulation of ADCY1 1 0.24 2.23 0.22
182 INT224130 Positive_regulation of Adora2a Positive_regulation of ADCY1 1 0.01 0.11 0.22
183 INT146826 Binding of Galr1 and Gtpbp4 1 0.03 0.17 0.22
184 INT173357 Gnaq Positive_regulation of PRKCA 1 0.01 0 0.22
185 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21
186 INT72015 Binding of Adora2a and Gnai2 1 0.01 0 0.21
187 INT7332 CALM3 Positive_regulation of ADCY1 1 0.46 0.13 0.21
188 INT356089 Positive_regulation of Binding of Tg and Rab11a 1 0.00 0.07 0.21
189 INT181765 WISP3 Regulation of Gene_expression of RHOC 1 0.49 1.46 0.21
190 INT356099 Binding of Tg and Rab11a 1 0.00 0.07 0.21
191 INT72019 Binding of Gnaq and Ptprg 1 0.01 0 0.21
192 INT224133 Negative_regulation of Adora2b Positive_regulation of ADCY1 1 0.01 0.1 0.2
193 INT302731 Binding of Gfm1 and Hk 1 0.01 1 0.2
194 INT102743 Binding of SEPT5 and Vwf 1 0.01 0.35 0.2
195 INT143973 Rac1 Positive_regulation of Vti1b 1 0.00 0.16 0.2
196 INT224134 Adora2b Positive_regulation of ADCY1 1 0.01 0.1 0.2
197 INT302732 Positive_regulation of Binding of Gfm1 and Hk 1 0.01 1 0.2
198 INT95896 Npy Positive_regulation of Positive_regulation of Gtpbp4 1 0.12 0 0.2
199 INT180435 Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
200 INT180444 Positive_regulation of Acot1 Positive_regulation of Rhoa 1 0.08 0.43 0.19

Single Events

The table below shows the top 100 pain related interactions that have been reported for GTP catabolic process. They are ordered first by their pain relevance and then by number of times they were reported in GTP catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96
2 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9
3 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97
4 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
5 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
6 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53
7 INT12617 Regulation of ADCY1 41 0.61 7.38 15.94
8 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
9 INT27627 Binding of Rac1 41 0.41 22.88 13.68
10 INT21421 Regulation of Gtpbp4 15 0.30 2.7 13.49
11 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21
12 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
13 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93
14 INT40486 Positive_regulation of Positive_regulation of ADCY1 20 0.48 4.29 11.33
15 INT204112 Gene_expression of GEM 43 0.75 38.74 11.23
16 INT67915 Negative_regulation of Gtpbp4 18 0.33 6.31 10.17
17 INT139443 Positive_regulation of GCH1 9 0.69 8.2 10.14
18 INT12620 Negative_regulation of Negative_regulation of ADCY1 16 0.44 2.98 10.1
19 INT62919 Regulation of Gnas 22 0.43 5.61 9.55
20 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
21 INT1682 Negative_regulation of Rem1 28 0.37 7.38 8.4
22 INT54681 Negative_regulation of Positive_regulation of ADCY1 16 0.38 2.7 8.14
23 INT68434 Gene_expression of Gtpbp4 15 0.54 5.5 7.91
24 INT264910 Positive_regulation of Gnaz 1 0.30 0 7.82
25 INT14207 Gene_expression of DNM2 20 0.67 5.76 7.64
26 INT152347 Binding of GCH1 8 0.37 6.13 7.36
27 INT6341 Binding of Gtpbp4 11 0.44 1.54 7.3
28 INT77756 Positive_regulation of GTPBP4 16 0.11 2.6 7.29
29 INT234813 Gene_expression of RAB5A 58 0.66 3.67 6.48
30 INT103723 Regulation of Positive_regulation of Gtpbp4 5 0.22 1.56 6.35
31 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33
32 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32
33 INT163776 Regulation of GCH1 7 0.27 4.58 6.16
34 INT20899 Negative_regulation of GNAI1 12 0.57 4.24 6.07
35 INT34742 Gene_expression of Gnat3 44 0.67 6.83 5.65
36 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54
37 INT72000 Gene_expression of Gnaq 17 0.75 3.12 5.48
38 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45
39 INT80881 Phosphorylation of ADCY1 7 0.69 1.22 5.29
40 INT33854 Localization of OPA1 19 0.65 10.55 5.04
41 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5
42 INT62920 Regulation of Gnai1 3 0.52 0.08 4.78
43 INT255981 Localization of RAB5A 3 0.68 0.88 4.76
44 INT269476 Binding of RAB5A 1 0.41 0 4.76
45 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
46 INT17391 Gene_expression of GNAI1 11 0.75 5.26 4.7
47 INT17393 Positive_regulation of GNAI1 17 0.49 2.42 4.66
48 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54
49 INT14574 Positive_regulation of Negative_regulation of ADCY1 9 0.66 2.45 4.39
50 INT96464 Positive_regulation of GEM 7 0.45 5.48 4.37
51 INT98357 Binding of Gnas 11 0.41 1.87 4.35
52 INT34829 Positive_regulation of Gnat3 27 0.46 5.24 4.14
53 INT74203 Positive_regulation of Positive_regulation of Gtpbp4 6 0.50 0.33 4.13
54 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03
55 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
56 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75
57 INT87408 Negative_regulation of ADCY2 3 0.01 0.1 3.68
58 INT25136 Localization of Gnat3 23 0.75 5.01 3.65
59 INT126685 Gene_expression of Rem1 30 0.65 11.21 3.61
60 INT53706 Positive_regulation of Kras 13 0.67 9.26 3.57
61 INT24883 Regulation of OPA1 14 0.45 9.73 3.44
62 INT87281 Localization of ADCY1 7 0.64 1.84 3.42
63 INT121967 Regulation of RAC1 9 0.45 6.14 3.41
64 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
65 INT135815 Transcription of Gch1 1 0.60 0 3.32
66 INT139010 Regulation of Gfm1 16 0.32 5.02 3.27
67 INT137679 Localization of Gfm1 18 0.08 9.58 3.24
68 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
69 INT19393 Gene_expression of Gfm1 31 0.51 18.9 3.2
70 INT58475 Localization of Rac1 12 0.75 5.94 3.2
71 INT28166 Positive_regulation of Rem1 8 0.40 7.96 3.19
72 INT13179 Regulation of Positive_regulation of ADCY1 5 0.34 0.89 3.08
73 INT128179 Gene_expression of RHOA 7 0.64 2.48 3.01
74 INT301081 Positive_regulation of GNAT1 1 0.12 4.16 3
75 INT59309 Negative_regulation of Gene_expression of ADCY1 3 0.42 1.04 2.98
76 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
77 INT5913 Binding of OPA1 12 0.41 9.33 2.92
78 INT69641 Positive_regulation of ADCY2 5 0.32 0.18 2.87
79 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84
80 INT109833 Binding of GNB3 7 0.48 8.83 2.84
81 INT30815 Binding of ADCY1 7 0.36 0.21 2.79
82 INT150933 Negative_regulation of Positive_regulation of GCH1 3 0.58 1.8 2.77
83 INT13943 Localization of DNM2 4 0.52 0.07 2.75
84 INT234825 Positive_regulation of Gene_expression of RAB5A 16 0.59 1.15 2.71
85 INT11196 Negative_regulation of Gnat3 26 0.37 3.14 2.69
86 INT264915 Positive_regulation of Localization of Gnaz 1 0.19 0 2.68
87 INT80884 Positive_regulation of Phosphorylation of ADCY1 4 0.43 0.24 2.64
88 INT11426 Positive_regulation of Gene_expression of ADCY1 5 0.29 0.68 2.63
89 INT204116 Regulation of Gene_expression of GEM 8 0.29 8.66 2.6
90 INT204110 Positive_regulation of Gene_expression of GEM 11 0.67 8.85 2.57
91 INT150932 Positive_regulation of Gene_expression of GCH1 3 0.70 2.07 2.57
92 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
93 INT72013 Negative_regulation of Gnai2 5 0.35 0.09 2.44
94 INT111039 Gene_expression of Kras 20 0.60 15.42 2.39
95 INT128174 Positive_regulation of Gene_expression of RHOA 7 0.36 1.5 2.36
96 INT139008 Positive_regulation of Gfm1 21 0.35 7.79 2.34
97 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
98 INT283973 Transcription of GCH1 1 0.61 1.99 2.33
99 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
100 INT131850 Gene_expression of RHOC 17 0.72 29.06 2.28
101 INT283975 Negative_regulation of Localization of GCH1 1 0.38 1.99 2.27
102 INT135827 Positive_regulation of Transcription of Gch1 1 0.58 0 2.2
103 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
104 INT70987 Binding of RAC1 14 0.37 12.14 2.13
105 INT179311 Transcription of GNAS 2 0.10 0.67 2.08
106 INT69196 Positive_regulation of Rap1a 2 0.29 1.18 2.06
107 INT108903 Negative_regulation of GNAS 7 0.57 1.58 2.04
108 INT17390 Regulation of GNAI1 5 0.04 3.58 2.03
109 INT258637 Regulation of Gene_expression of GCH1 1 0.62 1.77 2.02
110 INT65993 Localization of Gnai1 1 0.46 0.08 2
111 INT112880 Positive_regulation of Gnaq 17 0.49 1.97 1.95
112 INT68435 Regulation of Gene_expression of Gtpbp4 4 0.34 0.96 1.89
113 INT9297 Localization of Gtpbp4 4 0.17 0.88 1.89
114 INT25871 Negative_regulation of Gnaz 3 0.23 0 1.89
115 INT117980 Regulation of Rac1 10 0.45 3.72 1.88
116 INT135820 Regulation of Gch1 1 0.59 0 1.88
117 INT126626 Positive_regulation of Rhoa 14 0.69 4.43 1.87
118 INT57618 Binding of GTPBP4 9 0.43 1.61 1.87
119 INT301080 Binding of GNAT1 1 0.10 2.04 1.85
120 INT146193 Negative_regulation of Positive_regulation of Rhoa 3 0.42 3 1.84
121 INT240058 Gene_expression of RHOB 2 0.55 4.29 1.84
122 INT85348 Localization of RHOA 12 0.59 4.81 1.83
123 INT17387 Gene_expression of Gnaz 3 0.50 0.4 1.81
124 INT128168 Positive_regulation of Gna12 1 0.01 0 1.76
125 INT134991 Regulation of Rem1 4 0.28 3.45 1.71
126 INT25192 Positive_regulation of Gene_expression of GNAI1 5 0.49 1.08 1.7
127 INT234827 Positive_regulation of RAB5A 3 0.59 0.54 1.69
128 INT109975 Positive_regulation of Kras 14 0.45 12.72 1.68
129 INT96823 Positive_regulation of Positive_regulation of GTPBP4 3 0.05 0.41 1.67
130 INT174656 Binding of NCF1 5 0.37 6.46 1.65
131 INT87289 Positive_regulation of Localization of ADCY1 3 0.43 0.36 1.65
132 INT31616 Protein_catabolism of DNM2 5 0.75 1.61 1.63
133 INT110189 Regulation of Gnaq 3 0.02 0.26 1.63
134 INT240059 Binding of RHOB 7 0.48 3.96 1.59
135 INT6438 Positive_regulation of RAN 6 0.42 2.09 1.59
136 INT80890 Negative_regulation of Phosphorylation of ADCY1 2 0.36 0.24 1.57
137 INT71999 Negative_regulation of Gene_expression of Gnaq 3 0.41 0.08 1.56
138 INT72310 Regulation of Regulation of ADCY1 6 0.24 1.24 1.55
139 INT128170 Gene_expression of Gna12 1 0.01 0 1.54
140 INT93624 Negative_regulation of Kras 3 0.41 1.15 1.52
141 INT9953 Positive_regulation of Gnas 10 0.34 3.21 1.51
142 INT146190 Negative_regulation of Localization of Rhoa 4 0.42 1.64 1.5
143 INT72008 Gene_expression of Gnai2 4 0.38 0.42 1.49
144 INT121347 Binding of GNAS 8 0.13 3.99 1.47
145 INT54190 Binding of Gnai1 2 0.34 0.28 1.47
146 INT94639 Negative_regulation of Gene_expression of Gnai1 1 0.02 0.08 1.46
147 INT254072 Gene_expression of SEPT5 23 0.16 8.29 1.43
148 INT58930 Negative_regulation of RAC1 14 0.55 7.55 1.4
149 INT162308 Phosphorylation of GNAS 3 0.01 1.71 1.4
150 INT15990 Binding of Gfm1 10 0.31 8.53 1.37
151 INT242902 Gene_expression of NCF1 12 0.78 9.34 1.36
152 INT131848 Positive_regulation of Gene_expression of RHOC 9 0.64 15.43 1.36
153 INT135822 Gene_expression of Gch1 2 0.50 0.77 1.35
154 INT69195 Negative_regulation of Rap1a 1 0.10 0.34 1.33
155 INT264906 Localization of Gnaz 1 0.28 0 1.33
156 INT148562 Positive_regulation of GNAS 13 0.16 5.31 1.32
157 INT264899 Positive_regulation of Positive_regulation of Gnaz 1 0.19 0 1.32
158 INT79099 Negative_regulation of Positive_regulation of Gtpbp4 4 0.20 0.06 1.31
159 INT229794 Positive_regulation of RAB7A 2 0.65 11.68 1.31
160 INT54587 Positive_regulation of Hras1 12 0.27 5.54 1.3
161 INT94640 Gene_expression of Gnai1 1 0.04 0.08 1.29
162 INT142992 Phosphorylation of RHOA 3 0.80 0.87 1.28
163 INT128176 Regulation of RHOA 13 0.44 4.35 1.26
164 INT80887 Negative_regulation of Regulation of ADCY1 3 0.35 0.1 1.26
165 INT25806 Binding of GNAI1 5 0.47 0.15 1.24
166 INT21167 Regulation of NCF1 3 0.15 0.75 1.24
167 INT111859 Regulation of Rhoa 3 0.61 0.23 1.22
168 INT110188 Regulation of Gene_expression of Gnaq 2 0.25 0.85 1.22
169 INT16013 Gene_expression of Rac1 52 0.75 23.79 1.21
170 INT98062 Regulation of Gene_expression of Rac1 4 0.39 1.41 1.21
171 INT229791 Gene_expression of RAB7A 2 0.73 6.48 1.21
172 INT57619 Gene_expression of GTPBP4 3 0.04 0.22 1.2
173 INT158831 Phosphorylation of Gfm1 10 0.58 5.99 1.19
174 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
175 INT75891 Regulation of ADCY2 3 0.06 0.06 1.17
176 INT229792 Negative_regulation of Positive_regulation of RAB7A 1 0.40 1.49 1.17
177 INT96463 Regulation of Positive_regulation of GEM 1 0.01 0.32 1.16
178 INT122891 Negative_regulation of Gch1 4 0.16 1.83 1.15
179 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13
180 INT77356 Positive_regulation of Gnai1 2 0.63 0.09 1.13
181 INT283974 Negative_regulation of Transcription of GCH1 1 0.38 0.99 1.13
182 INT283972 Localization of GCH1 1 0.67 0.99 1.13
183 INT283976 Positive_regulation of Binding of GCH1 1 0.45 1.27 1.13
184 INT114326 Phosphorylation of ADCY6 2 0.70 0.05 1.11
185 INT81440 Regulation of GTPBP4 3 0.02 0.09 1.1
186 INT25451 Negative_regulation of Gfm1 13 0.27 8.22 1.06
187 INT124810 Gene_expression of ADCY6 6 0.65 0 1.06
188 INT150931 Negative_regulation of GCH1 6 0.59 1.23 1.05
189 INT136817 Negative_regulation of Positive_regulation of RHOA 8 0.57 0 1.04
190 INT72868 Transcription of ADCY1 4 0.57 0.69 1.04
191 INT158833 Regulation of Gene_expression of Gfm1 3 0.32 1.34 1.04
192 INT72002 Negative_regulation of Gnaq 7 0.35 0.2 1.02
193 INT127714 Negative_regulation of GEM 6 0.37 2.24 1.01
194 INT204058 Regulation of Gene_expression of Kras 4 0.24 7.54 1.01
195 INT86798 Positive_regulation of Binding of Gtpbp4 1 0.29 0 1.01
196 INT67174 Negative_regulation of Rac1 22 0.56 10.72 0.99
197 INT111035 Positive_regulation of Gene_expression of Kras 5 0.31 3.31 0.99
198 INT204108 Negative_regulation of Gene_expression of GEM 1 0.31 2.93 0.99
199 INT180423 Positive_regulation of Gene_expression of Rhoa 7 0.40 6.22 0.98
200 INT79081 Negative_regulation of Gene_expression of Gnaz 1 0.03 0 0.98
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