GO:0006195

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Name purine nucleotide catabolic process
Categary Process
Go Slim No
Go Link GO:0006195
Unique Molecular Interactions 22
Total Molecular Interactions 28
Total Single Events 502
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for purine nucleotide catabolic process. They are ordered first by their pain relevance and then by number of times they were reported for purine nucleotide catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT253863 Binding of LBP and PNP 1 0.13 1.5 1.5
2 INT42580 CAT Negative_regulation of POMC 1 0.20 0.42 1.26
3 INT164722 Avp Regulation of NT5C 1 0.06 0.88 1.15
4 INT287132 Binding of NT5E and Comt 1 0.03 0.11 0.73
5 INT164721 Binding of NT5C and Acot1 1 0.04 0.45 0.65
6 INT164723 Binding of Avp and NT5C 1 0.07 0.45 0.65
7 INT150965 NT5C2 Positive_regulation of PRKG1 1 0.04 0.07 0.62
8 INT287131 Negative_regulation of Binding of NT5E and Comt 1 0.03 0.06 0.23
9 INT287130 Positive_regulation of Binding of NT5E and Comt 1 0.04 0 0.12
10 INT62775 Regulation of Binding of NT5E and OPRK1 1 0.03 0 0.1
11 INT186246 Binding of CAT and SCN5A 1 0.03 0.47 0.1
12 INT62776 Binding of NT5E and OPRK1 1 0.02 0 0.1
13 INT186245 Binding of AGRP and CAT 1 0.02 0.53 0.1
14 INT31987 NTS Positive_regulation of Binding of GDA 1 0.50 0 0.08
15 INT166919 Binding of CAT and GSTK1 1 0.09 0.16 0.07
16 INT267998 Binding of XDH and Nos1 1 0.02 0.46 0.06
17 INT316185 NUDT1 Regulation of ENO2 1 0.11 2.83 0.05
18 INT252767 CAT Regulation of Gpx1 1 0.00 0.25 0.04
19 INT311144 CAT Positive_regulation of APRT 1 0.01 0 0.03
20 INT285403 Binding of CAT and MPO 1 0.30 0.9 0
21 INT311145 CAT Positive_regulation of Protein_catabolism of APRT 1 0.01 0 0
22 INT232056 Binding of DDR1 and PNP 1 0.01 0.55 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for purine nucleotide catabolic process. They are ordered first by their pain relevance and then by number of times they were reported in purine nucleotide catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67
2 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18
3 INT253864 Negative_regulation of PNP 13 0.26 6.84 6.67
4 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38
5 INT62784 Gene_expression of NT5E 46 0.65 15.95 3.72
6 INT174232 Gene_expression of PNP 36 0.30 8.74 3.17
7 INT14902 Negative_regulation of XDH 38 0.55 24.19 2.86
8 INT22129 Positive_regulation of Gene_expression of CAT 11 0.67 4.23 2.37
9 INT57115 Negative_regulation of NT5E 8 0.57 4.35 2.03
10 INT48035 Positive_regulation of NT5C2 5 0.67 2.42 1.91
11 INT3892 Positive_regulation of XDH 8 0.67 8.57 1.5
12 INT164720 Positive_regulation of Localization of NT5C 1 0.06 0.87 1.39
13 INT96420 Positive_regulation of NT5E 9 0.49 3.7 1.38
14 INT155036 Localization of NT5E 6 0.73 4.1 1.35
15 INT110569 Gene_expression of XDH 31 0.75 18.35 1.34
16 INT91122 Localization of CAT 6 0.78 4.13 1.19
17 INT53682 Regulation of Gene_expression of CAT 2 0.60 0.36 0.96
18 INT66314 Negative_regulation of Positive_regulation of CAT 4 0.42 0.8 0.91
19 INT58405 Gene_expression of GDA 3 0.75 0.24 0.86
20 INT287128 Protein_catabolism of NT5E 2 0.11 0.64 0.76
21 INT294133 Regulation of Gene_expression of NT5E 4 0.12 1.36 0.71
22 INT164717 Localization of NT5C 1 0.09 0.43 0.69
23 INT150966 Positive_regulation of Positive_regulation of NT5C2 1 0.49 0.07 0.63
24 INT164718 Regulation of NT5C 3 0.19 1.36 0.62
25 INT107417 Regulation of CAT 8 0.60 2.4 0.61
26 INT155035 Binding of NT5E 3 0.36 1.78 0.61
27 INT42882 Positive_regulation of GDA 2 0.45 1.26 0.58
28 INT164719 Regulation of Regulation of NT5C 1 0.03 0.44 0.58
29 INT130387 Binding of CAT 4 0.36 2.39 0.55
30 INT179373 Localization of XDH 3 0.20 1.97 0.54
31 INT251661 Phosphorylation of NT5E 2 0.21 1.59 0.46
32 INT96419 Positive_regulation of Gene_expression of NT5E 3 0.49 1.46 0.41
33 INT201844 Transcription of GDA 1 0.05 1.2 0.38
34 INT201848 Negative_regulation of GDA 1 0.06 1.21 0.38
35 INT201849 Negative_regulation of Transcription of GDA 1 0.04 1.21 0.38
36 INT84981 Negative_regulation of Gene_expression of CAT 3 0.41 0.35 0.35
37 INT126817 Phosphorylation of GDA 1 0.79 0 0.35
38 INT287129 Regulation of NT5E 3 0.12 1.02 0.32
39 INT261239 Binding of XDH 10 0.34 3.16 0.31
40 INT354743 Gene_expression of NT5C 1 0.20 1.72 0.25
41 INT294138 Positive_regulation of Localization of NT5E 1 0.14 0.41 0.21
42 INT294141 Regulation of Localization of NT5E 1 0.12 0.42 0.21
43 INT44173 Regulation of GDA 1 0.44 0 0.19
44 INT267995 Negative_regulation of Negative_regulation of XDH 2 0.30 0.77 0.15
45 INT223026 Regulation of XDH 2 0.32 2.38 0.15
46 INT181919 Protein_catabolism of CAT 1 0.15 0.54 0.12
47 INT263205 Negative_regulation of Gene_expression of XDH 2 0.41 0.63 0.1
48 INT320095 Negative_regulation of Binding of XDH 1 0.16 0.46 0.1
49 INT110568 Positive_regulation of Gene_expression of XDH 7 0.49 5.14 0.09
50 INT266463 Positive_regulation of Positive_regulation of CAT 2 0.49 1.85 0.09
51 INT31988 Binding of GDA 1 0.36 0 0.08
52 INT354744 Binding of NT5C 1 0.10 0.29 0.08
53 INT267994 Positive_regulation of Negative_regulation of XDH 1 0.33 0.37 0.07
54 INT267997 Positive_regulation of Positive_regulation of XDH 1 0.35 0.83 0.03
55 INT271152 Positive_regulation of NUDT1 4 0.17 1.34 0
56 INT224345 Gene_expression of NUDT1 4 0.17 4.46 0
57 INT232066 Binding of PNP 3 0.13 0.28 0
58 INT110570 Regulation of Gene_expression of XDH 3 0.32 1.36 0
59 INT232073 Regulation of PNP 2 0.12 0.33 0
60 INT271153 Binding of NUDT1 2 0.09 2.44 0
61 INT174238 Positive_regulation of Gene_expression of PNP 2 0.16 0.69 0
62 INT110572 Transcription of XDH 1 0.52 0.15 0
63 INT285458 Negative_regulation of Gene_expression of PNP 1 0.11 0 0
64 INT107418 Negative_regulation of Regulation of CAT 1 0.31 0 0
65 INT285456 Positive_regulation of PNP 1 0.13 0.08 0
66 INT285457 Localization of PNP 1 0.21 0 0
67 INT110571 Positive_regulation of Transcription of XDH 1 0.45 0 0
68 INT329193 Regulation of Binding of NT5E 1 0.07 0.67 0
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