GO:0006208

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Name pyrimidine base catabolic process
Categary Process
Go Slim No
Go Link GO:0006208
Unique Molecular Interactions 44
Total Molecular Interactions 51
Total Single Events 451
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for pyrimidine base catabolic process. They are ordered first by their pain relevance and then by number of times they were reported for pyrimidine base catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT178576 CNTN2 Positive_regulation of DPYD 1 0.05 2.18 0.76
2 INT49904 Gtf3a Regulation of Dpys 1 0.02 0.06 0.28
3 INT221627 Binding of Dpysl2 and Fer 1 0.21 0.27 0.2
4 INT221641 Binding of Dpysl2 and Fes 1 0.23 0.27 0.2
5 INT24475 Dpys Regulation of Brs3 1 0.18 0 0.18
6 INT135973 Dpys Negative_regulation of Gene_expression of Nos2 1 0.06 0.26 0.17
7 INT135970 Dpys Negative_regulation of Nos2 1 0.05 0.25 0.17
8 INT221662 Fes Positive_regulation of Phosphorylation of Dpysl2 1 0.24 0.14 0.14
9 INT221615 Dpysl2 Positive_regulation of Gene_expression of Fes 1 0.21 0.14 0.13
10 INT221636 Dpysl2 Positive_regulation of Fer 1 0.21 0.14 0.13
11 INT268943 Binding of Crmp1 and Positive_regulation of Regulation of Ros1 1 0.00 0.2 0.11
12 INT221659 Binding of Fes and Dpysl5 1 0.16 0.58 0.11
13 INT335742 Binding of PDB1 and Dpyd 1 0.02 1.75 0.09
14 INT221631 Dpysl2 Negative_regulation of Fes 1 0.21 0.42 0.07
15 INT221646 Dpysl2 Negative_regulation of Fer 1 0.08 0.42 0.07
16 INT221658 Sema3a Positive_regulation of Phosphorylation of Crmp1 1 0.12 0.4 0.05
17 INT221654 Fes Positive_regulation of Phosphorylation of Crmp1 1 0.18 0.37 0.04
18 INT241450 Binding of Rhoa and Dpysl3 1 0.02 0 0.03
19 INT268942 Binding of Crmp1 and Fig4 1 0.01 0.28 0.03
20 INT337066 Binding of DPYD and FRA1E 1 0.19 0.8 0
21 INT268945 Ros1 Regulation of Binding of Crmp1 1 0.00 0.21 0
22 INT268948 Regulation of Ros1 Positive_regulation of Localization of Crmp1 1 0.00 0.54 0
23 INT268944 Ros1 Regulation of Localization of Crmp1 1 0.00 0.21 0
24 INT294880 DPYD Positive_regulation of Ephb1 1 0.00 0.53 0
25 INT303469 CDH3 Negative_regulation of Dpyd 1 0.01 0 0
26 INT294828 DPYD Positive_regulation of PIK3CB 1 0.00 0.51 0
27 INT221616 Binding of Dpysl2 and Sh2 1 0.06 0 0
28 INT163633 Col4a4 Regulation of Dpyd 1 0.04 0.06 0
29 INT221629 Dpysl2 Negative_regulation of Phosphorylation of Fer 1 0.18 0 0
30 INT221622 Dpysl2 Positive_regulation of Fes 1 0.24 0 0
31 INT294827 DPYD Positive_regulation of Gene_expression of REXO1 1 0.01 0.47 0
32 INT294831 DPYD Positive_regulation of Positive_regulation of RASGRP1 1 0.00 0.53 0
33 INT221635 Dpysl2 Negative_regulation of Phosphorylation of Fes 1 0.20 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for pyrimidine base catabolic process. They are ordered first by their pain relevance and then by number of times they were reported in pyrimidine base catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49464 Positive_regulation of Dpys 7 0.47 0.5 6.96
2 INT143623 Binding of Dpysl2 7 0.48 3.18 3.93
3 INT49896 Regulation of Dpys 5 0.58 0.16 2.41
4 INT221573 Gene_expression of Dpysl2 9 0.78 4.32 1.88
5 INT70781 Positive_regulation of Dpyd 6 0.54 2.51 1.26
6 INT106261 Negative_regulation of DPYD 16 0.59 15.02 1.19
7 INT94690 Gene_expression of DPYD 12 0.75 4.6 1.07
8 INT22991 Gene_expression of Dpys 3 0.73 0.08 0.91
9 INT108520 Negative_regulation of Dpys 2 0.12 0.21 0.9
10 INT93908 Negative_regulation of Dpyd 9 0.45 3.19 0.78
11 INT178587 Positive_regulation of DPYD 4 0.50 4.7 0.74
12 INT49903 Transcription of Dpys 1 0.67 0.25 0.74
13 INT119633 Transcription of Dpyd 4 0.72 0.68 0.54
14 INT283084 Regulation of Dpysl2 1 0.38 0 0.53
15 INT221564 Phosphorylation of Dpysl2 8 0.36 1.48 0.5
16 INT49465 Binding of Dpys 1 0.26 0.1 0.49
17 INT342920 Localization of Dpys 1 0.73 1.41 0.44
18 INT178586 Localization of DPYD 1 0.36 0.76 0.42
19 INT147959 Localization of Dpyd 2 0.53 1.37 0.4
20 INT221544 Phosphorylation of Crmp1 1 0.29 1.33 0.4
21 INT94691 Binding of DPYD 2 0.47 0 0.39
22 INT241416 Negative_regulation of Dpysl2 2 0.41 0.17 0.36
23 INT163630 Negative_regulation of Dpyd 3 0.58 0.52 0.34
24 INT49898 Positive_regulation of Positive_regulation of Dpys 1 0.47 0.07 0.29
25 INT154137 Regulation of Dpyd 2 0.18 0.82 0.28
26 INT49901 Regulation of Gene_expression of Dpys 1 0.42 0.08 0.28
27 INT163628 Regulation of Transcription of Dpyd 1 0.27 0.25 0.27
28 INT97149 Binding of Dpyd 3 0.14 1.73 0.25
29 INT49900 Positive_regulation of Transcription of Dpys 1 0.65 0.09 0.25
30 INT221569 Phosphorylation of Dpysl5 1 0.32 0.88 0.22
31 INT268967 Binding of Crmp1 1 0.05 2.66 0.22
32 INT268958 Localization of Crmp1 1 0.08 2.45 0.22
33 INT49895 Regulation of Transcription of Dpys 1 0.25 0.1 0.2
34 INT129365 Negative_regulation of Dpys 1 0.38 0.08 0.17
35 INT221584 Regulation of Crmp1 1 0.08 0.37 0.12
36 INT221580 Regulation of Dpysl5 1 0.11 0.37 0.12
37 INT221559 Positive_regulation of Phosphorylation of Dpysl5 1 0.18 0.38 0.12
38 INT221525 Binding of Dpysl5 1 0.15 0.26 0.1
39 INT335728 Positive_regulation of Dpyd 1 0.17 1.74 0.09
40 INT268965 Negative_regulation of Crmp1 1 0.04 1.28 0.07
41 INT221551 Binding of Crmp1 1 0.11 0.06 0.03
42 INT268962 Phosphorylation of Crmp1 1 0.08 0.3 0.03
43 INT221566 Negative_regulation of Gene_expression of Dpysl2 1 0.19 0.11 0.03
44 INT241406 Positive_regulation of Phosphorylation of Dpysl2 1 0.13 0.34 0.03
45 INT221528 Gene_expression of Dpysl5 1 0.27 0.05 0.03
46 INT70782 Gene_expression of Dpyd 5 0.53 2.44 0
47 INT119632 Gene_expression of Dpyd 4 0.77 0.4 0
48 INT181315 Regulation of DPYD 2 0.54 3.64 0
49 INT268966 Gene_expression of Crmp1 2 0.07 1.13 0
50 INT268964 Regulation of Gene_expression of Crmp1 1 0.04 0.73 0
51 INT268970 Positive_regulation of Crmp1 1 0.05 0.22 0
52 INT258773 Negative_regulation of Binding of Dpyd 1 0.11 0.6 0
53 INT268959 Regulation of Binding of Crmp1 1 0.04 0.45 0
54 INT223288 Protein_catabolism of DPYD 1 0.46 0.11 0
55 INT337068 Transcription of DPYD 1 0.60 0 0
56 INT268968 Transcription of Crmp1 1 0.07 0.36 0
57 INT162118 Regulation of Transcription of Dpyd 1 0.18 0.1 0
58 INT163631 Regulation of Dpyd 1 0.45 0.06 0
59 INT120740 Gene_expression of Dpys 1 0.34 0.34 0
60 INT221568 Localization of Dpysl2 1 0.33 0 0
61 INT268961 Positive_regulation of Binding of Crmp1 1 0.05 0.85 0
62 INT154142 Regulation of Gene_expression of Dpyd 1 0.03 0.26 0
63 INT268960 Positive_regulation of Localization of Crmp1 1 0.07 0.34 0
64 INT162119 Transcription of Dpyd 1 0.36 0.1 0
65 INT268957 Negative_regulation of Transcription of Crmp1 1 0.04 0.36 0
66 INT268963 Regulation of Crmp1 1 0.04 1.02 0
67 INT221529 Positive_regulation of Gene_expression of Dpysl2 1 0.22 0 0
68 INT268969 Negative_regulation of Gene_expression of Crmp1 1 0.04 0.94 0
69 INT241408 Binding of Dpysl3 1 0.05 0 0
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