GO:0006260

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Name DNA replication
Categary Process
Go Slim No
Go Link GO:0006260
Unique Molecular Interactions 549
Total Molecular Interactions 748
Total Single Events 5349
Pain Genes Associated 77

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA replication. They are ordered first by their pain relevance and then by number of times they were reported for DNA replication. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT123451 Binding of YY1 and Adra2a 1 0.37 0 2.98
2 INT25708 Oprl1 Positive_regulation of Adra2a 1 0.25 0.15 2.63
3 INT18786 Binding of Adra2a and Nisch 2 0.19 0 1.7
4 INT73116 TYMS Negative_regulation of DNMT3B 1 0.24 0 1.6
5 INT73115 TYMS Negative_regulation of Positive_regulation of DNMT3B 1 0.24 0 1.6
6 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
7 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
8 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
9 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18
10 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18
11 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18
12 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17
13 INT136989 EGF Negative_regulation of Positive_regulation of KCNJ2 1 0.04 1.09 1.1
14 INT136988 EGF Negative_regulation of KCNJ2 1 0.04 1.09 1.04
15 INT41175 Adra2a Regulation of Th 1 0.59 0 1.04
16 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
17 INT63543 Binding of Adra2a and Serpini1 1 0.13 0 1
18 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
19 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
20 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
21 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
22 INT220744 EGF Positive_regulation of Gene_expression of KRT20 1 0.01 1.26 0.9
23 INT28921 Adra2a Positive_regulation of Localization of Prl 1 0.24 0 0.9
24 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
25 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
26 INT43796 Binding of CDS1 and Adra2a 1 0.06 0 0.86
27 INT220739 EGF Positive_regulation of Transcription of NAV1 1 0.31 0.16 0.83
28 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
29 INT110118 A630055G03Rik Regulation of Car2 1 0.01 0.35 0.81
30 INT84039 EGF Positive_regulation of Gene_expression of CPOX 2 0.11 1.88 0.8
31 INT84040 EGF Positive_regulation of CPOX 2 0.07 1.91 0.8
32 INT220747 Binding of PCa and EGF 1 0.05 1.42 0.8
33 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
34 INT63544 Adra2a Regulation of Nisch 1 0.18 0 0.79
35 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
36 INT117412 RYBP Negative_regulation of LIG4 1 0.00 0.42 0.76
37 INT108611 Adra2a Regulation of Gene_expression of Nos1 1 0.10 0 0.75
38 INT84283 Binding of Adra2a and Htr1f 1 0.16 0.15 0.74
39 INT15221 RRM1 Regulation of Localization of VIP 1 0.12 0.08 0.74
40 INT251729 Binding of FEN1 and EXOSC1 1 0.19 1.13 0.74
41 INT15222 RRM1 Regulation of VIP 1 0.12 0.08 0.74
42 INT220746 EGF Positive_regulation of Gene_expression of GOPC 1 0.13 0 0.72
43 INT306263 Binding of NFIB and TFAM 1 0.00 1.74 0.7
44 INT142994 Binding of UPF1 and FCMTE1 1 0.00 0.91 0.7
45 INT20688 Adra2a Regulation of Localization of Gh1 1 0.26 0.37 0.7
46 INT81968 Binding of PLEK and Adra2a 1 0.07 0.1 0.7
47 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
48 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
49 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
50 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
51 INT132152 Adra2a Regulation of Localization of Abat 1 0.03 0 0.66
52 INT153921 Positive_regulation of Adra2a Regulation of Ednrb 1 0.01 0 0.66
53 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
54 INT17187 Binding of Adra2a and Fabp6 1 0.16 0.69 0.61
55 INT17186 Positive_regulation of Binding of Adra2a and Fabp6 1 0.21 0.69 0.61
56 INT169287 EGF Positive_regulation of Localization of IL8 1 0.15 0.13 0.61
57 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
58 INT117958 Col4a4 Regulation of Repin1 1 0.01 0.39 0.6
59 INT199976 EGF Regulation of ITGB3BP 1 0.02 0.77 0.57
60 INT192291 OR5A1 Positive_regulation of Gene_expression of IGF1 1 0.02 0.93 0.57
61 INT41250 Binding of Adra2a and Eef1a1 1 0.06 0.4 0.56
62 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
63 INT121993 Binding of EGF and SGCG 1 0.40 0 0.55
64 INT164265 TGM7 Negative_regulation of CDK2 1 0.26 1.08 0.53
65 INT177504 Gabrg1 Positive_regulation of PCNA 1 0.07 0.22 0.52
66 INT220745 EGF Positive_regulation of Positive_regulation of PCa 1 0.05 0.79 0.52
67 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 0.06 0.57 0.52
68 INT305851 Polk Positive_regulation of Gene_expression of Tslp 1 0.29 0.9 0.51
69 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
70 INT98734 Egf Negative_regulation of Tk1 1 0.13 0.15 0.49
71 INT7851 Man2a2 Positive_regulation of Adra2a 1 0.13 0 0.49
72 INT295708 Binding of EGF and CCL2 1 0.01 0.79 0.49
73 INT108329 EGF Positive_regulation of Phosphorylation of EPHB2 4 0.48 3.96 0.48
74 INT146113 Binding of Adra2a and Lrp1 1 0.01 1.07 0.48
75 INT58578 Binding of RPA1 and TACR1 1 0.01 0 0.48
76 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
77 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46
78 INT39870 Odc1 Negative_regulation of Tk1 1 0.36 0.8 0.46
79 INT26448 Adra2a Regulation of Positive_regulation of Npy 1 0.06 0 0.46
80 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
81 INT237452 Binding of STAR and CHTF8 1 0.00 0.48 0.45
82 INT86380 Adra2a Regulation of Gene_expression of Tnf 1 0.15 0.79 0.44
83 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
84 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
85 INT311590 EGF Regulation of Gene_expression of CXCL10 1 0.23 0.51 0.43
86 INT56576 Adra2a Positive_regulation of Localization of Gnrh1 1 0.44 0 0.43
87 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
88 INT55395 Binding of Htr1a and Adra2a 1 0.42 0 0.43
89 INT311591 CXCL10 Regulation of Gene_expression of EGF 1 0.23 0.51 0.43
90 INT275849 PES1 Positive_regulation of Gene_expression of TNFAIP1 1 0.01 1.28 0.42
91 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41
92 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41
93 INT34987 Adra2a Positive_regulation of Localization of Gnrhr 1 0.43 0 0.4
94 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4
95 INT13715 PDYN Positive_regulation of TYMS 1 0.27 0 0.39
96 INT90807 EGF Positive_regulation of Oprd1 1 0.00 0.39 0.39
97 INT182492 IL1B Regulation of Gene_expression of IGF1 1 0.01 0.83 0.38
98 INT70656 Adra2a Regulation of Gene_expression of Npy 1 0.23 0 0.38
99 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37
100 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37
101 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36
102 INT305853 Polk Regulation of Gene_expression of Hand2 1 0.12 0.93 0.35
103 INT278749 NUP98 Positive_regulation of Gene_expression of PTGS2 1 0.46 1.28 0.35
104 INT305856 Polk Regulation of Gene_expression of TH1L 1 0.43 0.93 0.35
105 INT280479 Binding of Mecp2 and Sin3a 1 0.00 1.54 0.35
106 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34
107 INT344238 MCRS1 Regulation of TREX1 1 0.08 1.02 0.34
108 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34
109 INT309192 Binding of Car2 and Rbms1 1 0.05 0 0.34
110 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33
111 INT67030 Negative_regulation of Adra2a Negative_regulation of Etf1 1 0.00 0.64 0.33
112 INT51630 Binding of ACHE and OPRM1 1 0.11 0 0.33
113 INT51628 Binding of ACHE and DRD3 1 0.15 0 0.33
114 INT67028 Adra2a Negative_regulation of Nts 1 0.06 0.64 0.33
115 INT175552 Binding of CASR and UPF1 1 0.01 0.89 0.33
116 INT297972 MAPK14 Negative_regulation of ING5 1 0.21 1.67 0.33
117 INT67029 Adra2a Negative_regulation of Etf1 1 0.00 0.64 0.33
118 INT31182 Adra2a Regulation of Localization of Gh 1 0.01 0.35 0.32
119 INT220740 EGF Positive_regulation of Regulation of NAV1 1 0.31 0.61 0.32
120 INT220749 EGF Positive_regulation of Positive_regulation of KRT20 1 0.01 0.61 0.32
121 INT173947 Il6 Positive_regulation of Gene_expression of IGF1 1 0.05 1.02 0.31
122 INT51275 IGF1 Negative_regulation of INS 2 0.35 0.98 0.29
123 INT100946 TNF Positive_regulation of Localization of NFIB 1 0.01 1.3 0.29
124 INT142885 Positive_regulation of IGF1 Positive_regulation of TRPV1 1 0.04 0.24 0.29
125 INT100945 TNF Positive_regulation of NFIB 1 0.00 1.29 0.29
126 INT177478 Gnrhr Positive_regulation of Localization of IGF1 1 0.04 1.01 0.28
127 INT173949 Binding of IGF1 and Atp6v1e1 1 0.01 0.89 0.28
128 INT243214 Myst2 Negative_regulation of Gene_expression of Ptgs2 1 0.01 1.4 0.28
129 INT142884 IGF1 Positive_regulation of TRPV1 1 0.04 0.24 0.28
130 INT193027 EGF Positive_regulation of Positive_regulation of MRGPRX1 1 0.02 0 0.27
131 INT285243 EGF Positive_regulation of Egf 1 0.00 1.55 0.27
132 INT285238 EGF Positive_regulation of VEGFA 1 0.01 1.55 0.27
133 INT144255 EGF Regulation of Positive_regulation of NFKB1 1 0.41 0.66 0.27
134 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
135 INT95061 Binding of Adra2a and ADHD1 1 0.02 0.8 0.27
136 INT305849 Polk Positive_regulation of Gene_expression of Hand2 1 0.08 0.76 0.27
137 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
138 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26
139 INT68872 Ghrh Regulation of IGF1 1 0.09 0.18 0.26
140 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26
141 INT42635 Adra2a Positive_regulation of epi 1 0.00 0 0.26
142 INT305854 Polk Regulation of Gene_expression of Atp11c 1 0.05 0.73 0.26
143 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
144 INT55641 Binding of CHRM1 and Adra2a 1 0.00 0 0.24
145 INT7869 Gh Negative_regulation of IGF1 1 0.39 0.47 0.23
146 INT220750 EGF Positive_regulation of PCa 1 0.05 0.45 0.23
147 INT173294 LPA Positive_regulation of EGF 1 0.01 0.07 0.23
148 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23
149 INT173292 F2 Positive_regulation of EGF 1 0.00 0.07 0.23
150 INT193033 Binding of CHRM1 and EGF 1 0.01 1.96 0.22
151 INT173946 Igf1 Regulation of Gene_expression of IGF1 1 0.08 0.68 0.21
152 INT173944 IGF1 Regulation of Gene_expression of Igf1 1 0.08 0.68 0.21
153 INT193035 Positive_regulation of PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
154 INT305850 Polk Positive_regulation of Gene_expression of dp 1 0.07 0.64 0.21
155 INT173945 Hrt1 Positive_regulation of Positive_regulation of IGF1 1 0.01 0.32 0.21
156 INT188203 EGF Positive_regulation of Protein_catabolism of OSM 1 0.30 0.17 0.21
157 INT331602 Binding of SSRP1 and Tlr4 1 0.03 0.9 0.21
158 INT277318 Upf1 Positive_regulation of Atxn8os 1 0.01 0.77 0.21
159 INT322017 RPA1 Positive_regulation of IL1B 1 0.00 0 0.21
160 INT193025 PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
161 INT314076 Peo1 Negative_regulation of Il6 1 0.35 0.62 0.21
162 INT193036 EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
163 INT193032 Positive_regulation of EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
164 INT320492 KRT7 Positive_regulation of Pip 1 0.00 1.02 0.2
165 INT145152 Binding of EGF and EGFR 4 0.15 2.45 0.19
166 INT220146 Binding of IGF1 and IGFBP1 2 0.10 1.57 0.19
167 INT14869 Binding of EGF and TGFB3 1 0.14 0.69 0.19
168 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
169 INT153460 Inhba Positive_regulation of Gene_expression of Ctgf 1 0.77 1.14 0.19
170 INT305848 Polk Positive_regulation of dp 1 0.09 0 0.19
171 INT91862 RPA1 Negative_regulation of Transcription of ATG9B 1 0.03 0.46 0.19
172 INT153461 Tnf Positive_regulation of Gene_expression of Ctgf 1 0.48 1.13 0.19
173 INT173943 Binding of IGF1 and Il6 1 0.04 0.11 0.19
174 INT355733 Pdgfb Regulation of Transcription of Bdnf 1 0.10 0.86 0.19
175 INT186098 EGF Positive_regulation of MAP2K5 1 0.01 0.19 0.18
176 INT345209 Repin1 Positive_regulation of Positive_regulation of Trib3 1 0.00 0.88 0.18
177 INT345924 IL6 Regulation of Gene_expression of SPHAR 1 0.00 0.21 0.18
178 INT280487 Negative_regulation of Binding of Mecp2 and Sin3a 1 0.00 0.77 0.18
179 INT58579 Binding of INSRR and RPA1 1 0.00 0 0.18
180 INT300305 Mapk14 Positive_regulation of Gene_expression of Ctgf 1 0.19 1.25 0.17
181 INT314078 Peo1 Negative_regulation of Stat1 1 0.31 1.23 0.17
182 INT355829 Binding of SETBP1 and LIN9 1 0.00 0.06 0.17
183 INT305857 Polk Regulation of Gene_expression of IFN1@ 1 0.31 0.74 0.17
184 INT245332 ATR Regulation of IL6 1 0.03 0.35 0.17
185 INT355732 Pdgfb Negative_regulation of Bdnf 1 0.13 0.87 0.17
186 INT265892 IGF1 Positive_regulation of PIK3CG 1 0.18 1.96 0.16
187 INT59952 Gh Positive_regulation of IGF1 1 0.46 0.84 0.16
188 INT24668 Binding of COL7A1 and EGF 1 0.14 0.25 0.16
189 INT269758 Negative_regulation of IGF1 Negative_regulation of Positive_regulation of IGFBP2 1 0.10 2.15 0.16
190 INT73076 IGF1 Positive_regulation of GH1 4 0.45 0.99 0.15
191 INT293712 Binding of Adra2a and Atl1 1 0.06 0.83 0.15
192 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
193 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
194 INT153458 Ctgf Positive_regulation of Gene_expression of Il6 1 0.34 1.03 0.15
195 INT305846 Polk Positive_regulation of Gene_expression of Il4 1 0.13 0.24 0.15
196 INT182659 Positive_regulation of Gins4 Positive_regulation of Rem1 1 0.00 0.1 0.15
197 INT238329 EGF Regulation of Negative_regulation of ADAMTS5 1 0.03 0 0.14
198 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14
199 INT238338 Binding of EGF and Regulation of Gene_expression of GOPC 1 0.05 0 0.14
200 INT88410 BMP7 Negative_regulation of CDK2 1 0.35 0 0.14

Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA replication. They are ordered first by their pain relevance and then by number of times they were reported in DNA replication. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
2 INT7059 Regulation of Adra2a 89 0.62 18.24 48.43
3 INT7608 Positive_regulation of Adra2a 66 0.70 17.81 35.15
4 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47
5 INT7779 Negative_regulation of Adra2a 47 0.58 9.45 28
6 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32
7 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
8 INT8248 Binding of Adra2a 43 0.48 6.72 22.17
9 INT11157 Binding of EGF 88 0.48 53.73 21.25
10 INT3030 Gene_expression of Adra2a 37 0.68 5.58 19.76
11 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
12 INT14114 Binding of Adra2a 30 0.48 4.24 18.53
13 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42
14 INT12875 Regulation of Adra2a 26 0.45 7.51 17.35
15 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
16 INT5674 Gene_expression of Adra2a 34 0.77 6.14 15.13
17 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68
18 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
19 INT12455 Negative_regulation of Adra2a 30 0.54 5.63 10.14
20 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94
21 INT2036 Localization of EGF 42 0.77 21.5 9.74
22 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
23 INT34777 Localization of IGF1 82 0.80 42.68 8.62
24 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62
25 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36
26 INT6576 Localization of Adra2a 11 0.71 1.49 7.18
27 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81
28 INT185879 Gene_expression of CDC6 9 0.39 5.18 6.46
29 INT37227 Regulation of EGF 19 0.45 11.16 5.17
30 INT13650 Positive_regulation of Gene_expression of Adra2a 6 0.50 0.69 4.94
31 INT7716 Positive_regulation of Positive_regulation of Adra2a 9 0.68 0.8 4.69
32 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
33 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07
34 INT59836 Positive_regulation of Upf1 24 0.02 4.42 3.99
35 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96
36 INT94303 Gene_expression of Upf1 44 0.04 11.62 3.87
37 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57
38 INT8096 Positive_regulation of Gene_expression of EGF 21 0.69 13.43 3.47
39 INT138319 Positive_regulation of Rpa1 3 0.07 2.75 3.07
40 INT17389 Negative_regulation of Positive_regulation of Adra2a 6 0.58 0.99 3.06
41 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
42 INT16130 Binding of IGF1 67 0.48 27.43 2.95
43 INT7931 Positive_regulation of Protein_catabolism of Adra2a 1 0.70 0 2.9
44 INT31923 Positive_regulation of Positive_regulation of Adra2a 7 0.44 1.88 2.89
45 INT77339 Positive_regulation of RRM2 5 0.41 1.36 2.88
46 INT156148 Gene_expression of CTGF 16 0.78 9.98 2.87
47 INT117785 Regulation of Gene_expression of EGF 7 0.44 4.22 2.87
48 INT53707 Negative_regulation of RRM1 4 0.59 0.44 2.87
49 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81
50 INT31451 Negative_regulation of Gene_expression of Adra2a 4 0.43 1.03 2.72
51 INT221269 Binding of BRCA1 14 0.40 31.77 2.7
52 INT200963 Regulation of UPF1 10 0.01 2.18 2.67
53 INT11892 Gene_expression of ACHE 10 0.68 1.32 2.63
54 INT125439 Positive_regulation of NFIB 4 0.67 6.71 2.52
55 INT43212 Regulation of Gene_expression of Adra2a 4 0.45 0.24 2.48
56 INT213681 Gene_expression of TYMS 9 0.33 8.96 2.45
57 INT12456 Negative_regulation of Positive_regulation of Adra2a 4 0.37 1.35 2.42
58 INT140091 Gene_expression of Ctgf 26 0.78 14.21 2.39
59 INT27338 Regulation of ACHE 6 0.62 1.25 2.38
60 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3
61 INT53587 Positive_regulation of Binding of Adra2a 1 0.12 0 2.26
62 INT101572 Negative_regulation of Gene_expression of PCNA 24 0.53 13.87 2.21
63 INT156694 Binding of SET 10 0.36 3.77 2.21
64 INT14890 Localization of ACHE 5 0.80 0.47 2.21
65 INT117415 Negative_regulation of LIG4 4 0.04 1.59 2.17
66 INT112868 Gene_expression of Pcna 21 0.75 8.6 2.15
67 INT74425 Gene_expression of SPHAR 8 0.08 7.81 2.15
68 INT120650 Negative_regulation of UPF1 14 0.02 6.86 2.14
69 INT82226 Negative_regulation of Gene_expression of EGF 11 0.58 6.36 2.13
70 INT34196 Regulation of Binding of Adra2a 2 0.45 0 2.12
71 INT108335 Phosphorylation of EGF 17 0.80 7.3 2.09
72 INT31262 Positive_regulation of Binding of Adra2a 4 0.10 1.02 2.04
73 INT132971 Negative_regulation of Localization of IGF1 5 0.42 3.98 1.94
74 INT309185 Gene_expression of Rbms1 16 0.24 0.87 1.93
75 INT148702 Positive_regulation of UPF1 29 0.31 12.9 1.91
76 INT275860 Negative_regulation of Localization of TNFAIP1 1 0.03 4.41 1.91
77 INT306836 Negative_regulation of Gene_expression of CDC6 1 0.19 1.28 1.88
78 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85
79 INT213676 Negative_regulation of Gene_expression of TYMS 2 0.08 1.95 1.83
80 INT174240 Negative_regulation of TYMS 12 0.57 6.35 1.82
81 INT35368 Positive_regulation of Tk1 9 0.53 4.68 1.81
82 INT68952 Localization of PCNA 17 0.62 5.64 1.78
83 INT90800 Negative_regulation of Positive_regulation of EGF 5 0.40 2.78 1.77
84 INT8757 Binding of ACHE 10 0.48 5.84 1.72
85 INT127145 Gene_expression of SET 46 0.65 10.39 1.7
86 INT88412 Positive_regulation of CDK2 17 0.57 8.49 1.66
87 INT66709 Transcription of IGF1 13 0.71 5.65 1.64
88 INT14891 Positive_regulation of ACHE 10 0.70 5.37 1.64
89 INT305832 Gene_expression of Polk 1 0.48 0.49 1.64
90 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53
91 INT306875 Localization of CDC6 1 0.34 1.51 1.52
92 INT7780 Positive_regulation of Negative_regulation of Adra2a 2 0.50 0.09 1.48
93 INT59837 Regulation of Upf1 5 0.03 1.37 1.45
94 INT58581 Binding of RPA1 8 0.44 1.68 1.44
95 INT86382 Negative_regulation of Localization of EGF 5 0.43 1.75 1.44
96 INT10669 Localization of Fen1 3 0.57 0.36 1.44
97 INT7932 Protein_catabolism of Adra2a 1 1.00 0 1.44
98 INT53632 Regulation of Negative_regulation of Adra2a 1 0.23 0.08 1.41
99 INT103907 Negative_regulation of Upf1 15 0.37 4.3 1.4
100 INT243339 Localization of TNFAIP1 4 0.41 3.7 1.39
101 INT29262 Negative_regulation of Binding of Adra2a 4 0.40 0.25 1.37
102 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36
103 INT97280 Gene_expression of Tk1 11 0.77 16.17 1.32
104 INT95815 Regulation of Positive_regulation of Adra2a 4 0.45 1.45 1.32
105 INT200979 Regulation of Gene_expression of UPF1 4 0.28 2.19 1.31
106 INT219492 Negative_regulation of CDC6 2 0.20 1.74 1.31
107 INT214704 Phosphorylation of Tk1 4 0.80 4.27 1.29
108 INT7847 Positive_regulation of Localization of Adra2a 2 0.40 0.22 1.28
109 INT200972 Positive_regulation of Gene_expression of UPF1 6 0.31 1.51 1.23
110 INT103164 Binding of UPF1 4 0.29 4.15 1.22
111 INT79489 Transcription of Adra2a 2 0.61 2.38 1.22
112 INT58311 Regulation of Localization of EGF 3 0.54 1.06 1.16
113 INT192807 Gene_expression of SSRP1 14 0.49 19.28 1.15
114 INT115982 Positive_regulation of KRT7 18 0.50 19.81 1.14
115 INT88568 Positive_regulation of RRM1 4 0.41 1.81 1.14
116 INT91872 Gene_expression of RPA1 9 0.77 5.28 1.12
117 INT167477 Regulation of TREX1 1 0.24 1.04 1.12
118 INT28949 Negative_regulation of Positive_regulation of IGF1 11 0.42 5.03 1.11
119 INT151261 Negative_regulation of Nfib 2 0.47 2.12 1.11
120 INT281849 Binding of RRM2 5 0.17 0.43 1.07
121 INT151260 Gene_expression of Nfib 5 0.75 1.83 1.06
122 INT13817 Protein_catabolism of EGF 3 1.00 1.44 1.06
123 INT117955 Gene_expression of Repin1 2 0.29 1.14 1.06
124 INT72129 Positive_regulation of Positive_regulation of IGF1 11 0.50 4.61 1.05
125 INT105860 Positive_regulation of Positive_regulation of EGF 6 0.64 2.37 1.05
126 INT151262 Binding of Nfib 1 0.36 1.02 1.03
127 INT106735 Phosphorylation of CDK2 11 0.79 4.03 1.02
128 INT158278 Positive_regulation of Myst2 2 0.41 0.89 1.02
129 INT169407 Phosphorylation of IGF1 4 0.63 0.83 1.01
130 INT306847 Positive_regulation of Gene_expression of CDC6 1 0.23 0.16 0.99
131 INT306295 Regulation of NFIB 1 0.13 2.43 0.97
132 INT193846 Gene_expression of Nfix 42 0.78 5.64 0.96
133 INT167702 Negative_regulation of Rpa1 3 0.06 1.16 0.96
134 INT184992 Positive_regulation of CDC6 2 0.28 0.7 0.96
135 INT20687 Positive_regulation of Regulation of Adra2a 1 0.35 1.07 0.95
136 INT306882 Transcription of CDC6 1 0.24 0.57 0.92
137 INT18801 Negative_regulation of Negative_regulation of Adra2a 2 0.43 0 0.91
138 INT110116 Negative_regulation of A630055G03Rik 1 0.04 0.47 0.91
139 INT56816 Gene_expression of Tk1 7 0.59 4.92 0.9
140 INT164079 Regulation of Gene_expression of CTGF 4 0.44 2 0.9
141 INT163795 Negative_regulation of Repin1 2 0.37 1.46 0.9
142 INT81103 Phosphorylation of Tk1 4 0.40 3.07 0.87
143 INT118290 Regulation of Phosphorylation of EGF 1 0.32 0.72 0.87
144 INT28885 Regulation of Tk1 6 0.47 2.53 0.82
145 INT202241 Positive_regulation of Negative_regulation of IGF1 5 0.48 1.56 0.82
146 INT74421 Positive_regulation of Gene_expression of SPHAR 2 0.06 0.99 0.81
147 INT332756 Localization of TREX1 1 0.01 0 0.81
148 INT86957 Gene_expression of Peo1 3 0.55 2.61 0.78
149 INT14770 Localization of Adra2a 2 0.60 0.1 0.78
150 INT306276 Binding of NFIB 1 0.14 1.73 0.77
151 INT144540 Negative_regulation of Gene_expression of Sin3a 1 0.57 0.85 0.75
152 INT258791 Positive_regulation of CDK1 14 0.45 5.73 0.74
153 INT181326 Binding of TNFAIP1 2 0.29 0.81 0.74
154 INT144544 Gene_expression of Sin3a 1 0.75 0.84 0.74
155 INT251735 Binding of FEN1 1 0.17 1.13 0.74
156 INT120239 Gene_expression of NFIB 3 0.65 1.01 0.72
157 INT44409 Gene_expression of Fen1 3 0.59 0 0.72
158 INT11102 Negative_regulation of Regulation of Adra2a 2 0.42 1.5 0.71
159 INT70652 Negative_regulation of Binding of EGF 7 0.43 4.23 0.7
160 INT276010 Regulation of Positive_regulation of Rpa1 1 0.06 0.72 0.7
161 INT62273 Gene_expression of CDK1 19 0.75 8.43 0.68
162 INT160736 Negative_regulation of KRT7 9 0.41 10.08 0.68
163 INT105330 Gene_expression of CDK2 31 0.63 13.7 0.67
164 INT200961 Transcription of UPF1 2 0.01 0.52 0.67
165 INT7609 Regulation of Positive_regulation of Adra2a 3 0.32 0.59 0.66
166 INT158279 Regulation of Myst2 2 0.37 0.51 0.65
167 INT28886 Negative_regulation of Tk1 5 0.45 1.66 0.64
168 INT200949 Negative_regulation of Gene_expression of UPF1 1 0.01 0.81 0.64
169 INT230410 Negative_regulation of Gene_expression of TNFAIP1 3 0.16 3.67 0.63
170 INT124211 Protein_catabolism of IGF1 2 1.00 1.29 0.63
171 INT100948 Localization of NFIB 2 0.12 1.8 0.62
172 INT76623 Negative_regulation of Fen1 1 0.33 0.63 0.62
173 INT81102 Positive_regulation of Positive_regulation of Tk1 2 0.35 1.45 0.61
174 INT167701 Phosphorylation of Rpa1 1 0.01 0.16 0.61
175 INT217091 Positive_regulation of Rrm2 5 0.33 4.12 0.6
176 INT44413 Regulation of Fen1 2 0.39 0.44 0.6
177 INT113846 Negative_regulation of Positive_regulation of CDK2 1 0.48 0.39 0.6
178 INT277699 Gene_expression of Pdgfb 5 0.20 4.84 0.59
179 INT137223 Binding of Peo1 4 0.31 0.47 0.58
180 INT333877 Protein_catabolism of LIG4 2 0.03 2.03 0.57
181 INT260422 Positive_regulation of Localization of EGF 3 0.10 1.58 0.56
182 INT169957 Transcription of PCNA 7 0.34 0.94 0.55
183 INT221420 Positive_regulation of Gene_expression of BRCA1 2 0.24 2.17 0.55
184 INT82128 Negative_regulation of Transcription of Adra2a 1 0.18 1.32 0.55
185 INT59394 Regulation of Regulation of Adra2a 1 0.17 0 0.55
186 INT31363 Positive_regulation of Regulation of Adra2a 1 0.04 0 0.55
187 INT125578 Positive_regulation of Localization of IGF1 6 0.60 7.59 0.53
188 INT144394 Protein_catabolism of ACHE 1 0.89 0.24 0.53
189 INT181325 Positive_regulation of TNFAIP1 4 0.36 4.64 0.52
190 INT176264 Binding of PCNA 21 0.21 9.08 0.51
191 INT131931 Binding of KRT7 13 0.36 19.24 0.5
192 INT77904 Negative_regulation of Gene_expression of Adra2a 2 0.43 0.87 0.5
193 INT13717 Positive_regulation of TYMS 3 0.40 1.64 0.49
194 INT77338 Negative_regulation of RRM2 2 0.38 0 0.49
195 INT41146 Negative_regulation of Localization of Adra2a 1 0.37 0.1 0.49
196 INT44410 Binding of Fen1 1 0.42 0.19 0.49
197 INT163285 Negative_regulation of Phosphorylation of CDK2 2 0.32 0.52 0.48
198 INT217083 Gene_expression of Rrm2 10 0.47 4.16 0.47
199 INT158296 Positive_regulation of Gene_expression of Ctgf 5 0.47 4.82 0.47
200 INT241674 Negative_regulation of Transcription of PCNA 1 0.11 0.33 0.47
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