GO:0006268

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Name DNA unwinding involved in replication
Categary Process
Go Slim No
Go Link GO:0006268
Unique Molecular Interactions 24
Total Molecular Interactions 31
Total Single Events 195
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA unwinding involved in replication. They are ordered first by their pain relevance and then by number of times they were reported for DNA unwinding involved in replication. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT314076 Peo1 Negative_regulation of Il6 1 0.35 0.62 0.21
2 INT314078 Peo1 Negative_regulation of Stat1 1 0.31 1.23 0.17
3 INT69909 Binding of MYC and PURA 1 0.24 0 0.1
4 INT314075 Peo1 Regulation of Positive_regulation of Stat1 1 0.37 0.43 0.08
5 INT314072 Peo1 Negative_regulation of Cxcl10 1 0.24 0.39 0.07
6 INT333849 Binding of Mcm4 and Mir17 1 0.03 0.52 0.05
7 INT333841 Binding of Rad51 and Mir17 1 0.02 0.52 0.05
8 INT314073 Peo1 Negative_regulation of Nos2 1 0.11 0.32 0.04
9 INT314074 Peo1 Regulation of Cxcl10 1 0.25 0.21 0.03
10 INT314065 Peo1 Regulation of Nos2 1 0.18 0.2 0.03
11 INT314077 Peo1 Negative_regulation of Positive_regulation of Stat1 1 0.31 0.33 0.03
12 INT314742 Binding of RAD51 and Brca2 1 0.06 1.05 0
13 INT314743 Binding of RAD51 and Brca1 1 0.06 1.06 0
14 INT285772 ERCC1 Positive_regulation of Binding of RAD51 1 0.05 0 0
15 INT285771 ERCC1 Regulation of Binding of RAD51 1 0.05 0 0
16 INT268317 Cdk1 Positive_regulation of Mcm7 1 0.33 0.25 0
17 INT268324 Cdc20 Positive_regulation of Mcm7 1 0.09 0.25 0
18 INT189374 Binding of RAD51 and Rad54l 1 0.01 0 0
19 INT251822 Binding of POLG and C10orf2 1 0.42 0.29 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA unwinding involved in replication. They are ordered first by their pain relevance and then by number of times they were reported in DNA unwinding involved in replication. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86957 Gene_expression of Peo1 3 0.55 2.61 0.78
2 INT69914 Binding of PURA 1 0.29 0.1 0.73
3 INT137223 Binding of Peo1 4 0.31 0.47 0.58
4 INT314059 Negative_regulation of Peo1 1 0.31 2.22 0.44
5 INT251828 Negative_regulation of C10orf2 3 0.37 2.87 0.41
6 INT69910 Positive_regulation of PURA 1 0.25 0.1 0.34
7 INT69921 Positive_regulation of Binding of PURA 1 0.26 0.1 0.34
8 INT314063 Regulation of Peo1 1 0.22 0.64 0.32
9 INT69919 Regulation of PURA 1 0.37 0.1 0.26
10 INT86958 Positive_regulation of Peo1 1 0.36 0.33 0.18
11 INT226416 Negative_regulation of Mcm4 1 0.13 1.29 0.17
12 INT236392 Regulation of Rad51 1 0.00 0.3 0.14
13 INT302693 Localization of C10orf2 1 0.59 1 0.11
14 INT302695 Negative_regulation of Localization of C10orf2 1 0.33 1 0.11
15 INT251831 Positive_regulation of C10orf2 1 0.50 1.23 0.08
16 INT333790 Localization of Mcm4 1 0.34 0.52 0.05
17 INT333807 Localization of Rad51 1 0.24 0.52 0.05
18 INT314062 Phosphorylation of Peo1 1 0.45 0.3 0.04
19 INT182414 Gene_expression of RAD51 25 0.65 2.14 0.03
20 INT189353 Binding of RAD51 11 0.40 0.93 0
21 INT230323 Positive_regulation of RAD51 11 0.58 0.51 0
22 INT230316 Localization of RAD51 5 0.67 0.07 0
23 INT230328 Negative_regulation of RAD51 4 0.36 0 0
24 INT346635 Gene_expression of PURA 1 0.37 0.73 0
25 INT230311 Transcription of RAD51 1 0.69 0 0
26 INT296158 Negative_regulation of Rad51 1 0.17 0.11 0
27 INT230318 Regulation of RAD51 1 0.38 0 0
28 INT268314 Gene_expression of Mcm7 1 0.38 0.26 0
29 INT251833 Binding of C10orf2 1 0.37 0.47 0
30 INT262399 Negative_regulation of Localization of Peo1 1 0.19 0.77 0
31 INT262398 Localization of Peo1 1 0.34 0.77 0
32 INT256909 Positive_regulation of Mcm7 1 0.41 1.08 0
33 INT230301 Positive_regulation of Gene_expression of RAD51 1 0.58 0.16 0
34 INT296159 Gene_expression of Rad51 1 0.11 0.11 0
35 INT251826 Gene_expression of C10orf2 1 0.67 0.28 0
36 INT230321 Regulation of Binding of RAD51 1 0.38 0 0
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