GO:0006270

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Name DNA-dependent DNA replication initiation
Categary Process
Go Slim No
Go Link GO:0006270
Unique Molecular Interactions 23
Total Molecular Interactions 27
Total Single Events 109
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA-dependent DNA replication initiation. They are ordered first by their pain relevance and then by number of times they were reported for DNA-dependent DNA replication initiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
2 INT304277 CCNE1 Positive_regulation of IL1RN 1 0.00 1.93 0.31
3 INT304278 CCNE1 Positive_regulation of IL8 1 0.02 1.93 0.31
4 INT304280 CCNE1 Positive_regulation of IL6 1 0.00 1.93 0.31
5 INT69909 Binding of MYC and PURA 1 0.24 0 0.1
6 INT333849 Binding of Mcm4 and Mir17 1 0.03 0.52 0.05
7 INT250151 Binding of GSS and MCM3 1 0.01 1.38 0.04
8 INT170858 Binding of IFI27 and Ccne2 1 0.01 0.17 0
9 INT268316 Cdk1 Positive_regulation of Mcm3 1 0.28 0.25 0
10 INT268321 Cdc20 Positive_regulation of Mcm5 1 0.09 0.25 0
11 INT333843 Ccne1 Regulation of Regulation of Mir103-2 1 0.06 0 0
12 INT196434 Binding of Ccne2 and Cdc25a 1 0.01 0.48 0
13 INT314688 Binding of CCNE1 and CDK2 1 0.04 1.41 0
14 INT314678 Binding of CCNE1 and CCNE2 1 0.03 1.41 0
15 INT268317 Cdk1 Positive_regulation of Mcm7 1 0.33 0.25 0
16 INT274387 Binding of POLA1 and IGSF9 1 0.01 0.58 0
17 INT268324 Cdc20 Positive_regulation of Mcm7 1 0.09 0.25 0
18 INT322544 Binding of CDK2 and Ccne1 1 0.16 0 0
19 INT333850 Binding of Ccne1 and Cdk2 1 0.26 0 0
20 INT268323 Cdc20 Positive_regulation of Mcm3 1 0.08 0.25 0
21 INT268315 Cdk1 Positive_regulation of Mcm5 1 0.33 0.25 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA-dependent DNA replication initiation. They are ordered first by their pain relevance and then by number of times they were reported in DNA-dependent DNA replication initiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT146013 Negative_regulation of Gene_expression of Ccne1 4 0.21 1.19 0.85
2 INT146014 Gene_expression of Ccne1 5 0.54 1.31 0.84
3 INT146012 Negative_regulation of Ccne2 1 0.20 0.13 0.84
4 INT69914 Binding of PURA 1 0.29 0.1 0.73
5 INT58987 Positive_regulation of Ccne1 1 0.49 0 0.59
6 INT58988 Positive_regulation of Gene_expression of Ccne1 1 0.67 0 0.59
7 INT58989 Gene_expression of Ccne1 2 0.75 0.79 0.58
8 INT153763 Gene_expression of Mcm3 2 0.33 1.39 0.4
9 INT153764 Positive_regulation of Gene_expression of Mcm3 1 0.03 1.14 0.4
10 INT69910 Positive_regulation of PURA 1 0.25 0.1 0.34
11 INT69921 Positive_regulation of Binding of PURA 1 0.26 0.1 0.34
12 INT304298 Positive_regulation of CCNE1 2 0.46 2.95 0.31
13 INT69919 Regulation of PURA 1 0.37 0.1 0.26
14 INT264095 Negative_regulation of Gene_expression of Ccne2 1 0.02 0.34 0.22
15 INT170847 Gene_expression of Ccne2 6 0.58 2.98 0.21
16 INT42569 Binding of Ccne1 1 0.21 0.38 0.19
17 INT226416 Negative_regulation of Mcm4 1 0.13 1.29 0.17
18 INT268205 Gene_expression of Mcm5 4 0.65 2.62 0.1
19 INT302244 Negative_regulation of CCNE1 1 0.01 1.03 0.1
20 INT173183 Regulation of CCNE1 1 0.05 0.4 0.06
21 INT333790 Localization of Mcm4 1 0.34 0.52 0.05
22 INT290786 Phosphorylation of Ccne2 1 0.05 0.08 0.04
23 INT290804 Positive_regulation of Phosphorylation of Ccne2 1 0.03 0.08 0.04
24 INT302266 Negative_regulation of Phosphorylation of CCNE1 1 0.02 0.29 0.03
25 INT268211 Transcription of Mcm5 1 0.52 1.82 0.03
26 INT314725 Gene_expression of CCNE1 3 0.52 2.45 0
27 INT269897 Positive_regulation of Ccne1 2 0.35 0 0
28 INT282087 Regulation of Ccne1 2 0.19 1.44 0
29 INT310442 Gene_expression of POLA1 1 0.30 0.97 0
30 INT346635 Gene_expression of PURA 1 0.37 0.73 0
31 INT333800 Localization of Ccne1 1 0.53 0.22 0
32 INT250154 Binding of MCM3 1 0.01 0.57 0
33 INT277667 Positive_regulation of Gene_expression of Ccne2 1 0.01 0.52 0
34 INT333815 Regulation of Gene_expression of Ccne1 1 0.43 0 0
35 INT268314 Gene_expression of Mcm7 1 0.38 0.26 0
36 INT256915 Regulation of Ccne2 1 0.34 0.98 0
37 INT310440 Positive_regulation of POLA1 1 0.18 0.09 0
38 INT256905 Positive_regulation of Ccne2 1 0.52 1.08 0
39 INT310439 Regulation of POLA1 1 0.24 2.21 0
40 INT256909 Positive_regulation of Mcm7 1 0.41 1.08 0
41 INT282081 Positive_regulation of Gene_expression of Ccne1 1 0.04 0.29 0
42 INT310443 Negative_regulation of POLA1 1 0.16 0.31 0
43 INT204068 Negative_regulation of Gene_expression of Ccne1 1 0.03 0.47 0
44 INT333824 Transcription of Ccne1 1 0.48 0 0
45 INT314716 Positive_regulation of Gene_expression of CCNE1 1 0.16 1.48 0
46 INT322520 Binding of Ccne1 1 0.35 0 0
47 INT196432 Binding of Ccne2 1 0.03 0.48 0
48 INT302253 Phosphorylation of CCNE1 1 0.03 0.29 0
49 INT219491 Negative_regulation of MCM3 1 0.14 0.36 0
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