GO:0006281

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Name DNA repair
Categary Process
Go Slim No
Go Link GO:0006281
Unique Molecular Interactions 787
Total Molecular Interactions 1095
Total Single Events 7743
Pain Genes Associated 144

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA repair. They are ordered first by their pain relevance and then by number of times they were reported for DNA repair. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06
2 INT202959 Binding of BAG3 and MCRS1 1 0.11 7.46 3.14
3 INT123451 Binding of YY1 and Adra2a 1 0.37 0 2.98
4 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53
5 INT113715 Msh3 Positive_regulation of tf 1 0.11 0 2.47
6 INT39108 Binding of PDYN and YY1 2 0.50 0.44 2.14
7 INT227493 Binding of TCEA1 and SIRT2 1 0.01 1.55 1.93
8 INT104709 Msh3 Positive_regulation of Rbm39 1 0.01 0.07 1.76
9 INT62065 Binding of YY1 and Penk 3 0.14 0 1.69
10 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66
11 INT73116 TYMS Negative_regulation of DNMT3B 1 0.24 0 1.6
12 INT73115 TYMS Negative_regulation of Positive_regulation of DNMT3B 1 0.24 0 1.6
13 INT30042 Binding of YY1 and Gnrhr 1 0.18 0 1.47
14 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44
15 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
16 INT154114 PENK Positive_regulation of YY1 1 0.50 0.06 1.41
17 INT154113 POMC Positive_regulation of YY1 1 0.70 0.06 1.41
18 INT26893 OGG1 Negative_regulation of Gh1 1 0.12 0 1.37
19 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
20 INT83422 Binding of FANCB and IGHG3 3 0.12 5.09 1.22
21 INT59707 PSENEN Regulation of Negative_regulation of YY1 1 0.12 0.07 1.21
22 INT59203 ecs Positive_regulation of Negative_regulation of Ube2d3 1 0.00 1.93 1.15
23 INT202960 Binding of MCRS1 and CPP 1 0.14 2.49 1.13
24 INT56882 Binding of YY1 and Ppbp 1 0.01 0 1.11
25 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08
26 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06
27 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
28 INT59518 YY1 Positive_regulation of SGCG 1 0.50 0.32 0.99
29 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
30 INT106248 Binding of CCR5 and YY1 1 0.54 0.19 0.98
31 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
32 INT118204 ST14 Regulation of YY1 1 0.04 0 0.93
33 INT161915 Negative_regulation of Binding of POMC and YY1 1 0.33 0 0.88
34 INT30955 YY1 Negative_regulation of Negative_regulation of LH 1 0.23 0.47 0.87
35 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
36 INT151882 Binding of YY1 and DLL1 1 0.00 0 0.79
37 INT151883 Negative_regulation of Binding of YY1 and DLL1 1 0.00 0 0.79
38 INT29913 Binding of FANCB and Pomc 1 0.01 0 0.76
39 INT170369 Binding of Car2 and Nono 1 0.01 0 0.76
40 INT166672 YY1 Regulation of Binding of UGT1A6 1 0.48 0 0.76
41 INT117412 RYBP Negative_regulation of LIG4 1 0.00 0.42 0.76
42 INT166674 YY1 Regulation of Binding of PRKCA 1 0.38 0 0.75
43 INT150995 Sfpq Positive_regulation of Gene_expression of Il4 1 0.06 0.71 0.74
44 INT150997 Sfpq Positive_regulation of Gene_expression of Il10 1 0.09 0.71 0.74
45 INT251729 Binding of FEN1 and EXOSC1 1 0.19 1.13 0.74
46 INT202967 MCRS1 Negative_regulation of CPP 2 0.14 2.2 0.73
47 INT7049 Binding of YY1 and Oprd1 1 0.01 0 0.73
48 INT157541 Binding of YY1 and Regulation of Gene_expression of OPRM1 1 0.31 1.21 0.72
49 INT145121 Msh3 Positive_regulation of Oprm1 1 0.06 0.15 0.72
50 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
51 INT150993 Sfpq Positive_regulation of Gene_expression of Il1b 1 0.04 0.7 0.72
52 INT150996 Sfpq Positive_regulation of Gene_expression of Il6 1 0.04 0.7 0.72
53 INT145120 Msh3 Negative_regulation of Positive_regulation of Oprm1 1 0.05 0.15 0.72
54 INT166671 YY1 Regulation of Positive_regulation of UGT1A6 1 0.48 0 0.7
55 INT142994 Binding of UPF1 and FCMTE1 1 0.00 0.91 0.7
56 INT133942 Binding of YY1 and ARFGEF1 1 0.05 0 0.69
57 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
58 INT133936 Binding of DNM2 and YY1 1 0.29 0 0.69
59 INT150998 Sfpq Negative_regulation of Gene_expression of Il6 1 0.05 0.69 0.69
60 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69
61 INT74599 YY1 Negative_regulation of ADCY1 2 0.36 0.31 0.67
62 INT150994 Sfpq Negative_regulation of Gene_expression of Il1b 1 0.03 0.69 0.66
63 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65
64 INT149684 Negative_regulation of Parp1 Positive_regulation of Oprm1 1 0.51 0 0.65
65 INT114950 YY1 Positive_regulation of Positive_regulation of PPARA 1 0.52 0.25 0.64
66 INT185997 Binding of FANCB and fc 2 0.01 2.51 0.63
67 INT145122 Oprm1 Negative_regulation of Msh3 1 0.06 0.15 0.63
68 INT149681 Parp1 Regulation of Transcription of Oprm1 1 0.67 0 0.63
69 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
70 INT34005 YY1 Regulation of KNG1 1 0.04 0.38 0.63
71 INT135498 Binding of YY1 and MRGPRX4 1 0.00 0.2 0.62
72 INT148352 Binding of MC1R and XRCC3 1 0.36 0.34 0.62
73 INT149682 Parp1 Negative_regulation of Oprm1 1 0.47 0 0.6
74 INT225065 Binding of ETF1 and FANCB 1 0.01 2.07 0.59
75 INT59202 ecs Positive_regulation of Ube2d3 1 0.00 0.98 0.59
76 INT149683 Parp1 Negative_regulation of Transcription of Oprm1 1 0.47 0 0.58
77 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
78 INT74656 YY1 Positive_regulation of Localization of IL2 1 0.07 0.09 0.58
79 INT202972 Positive_regulation of MCRS1 Negative_regulation of CPP 1 0.16 1.64 0.57
80 INT202961 MCRS1 Negative_regulation of STC2 1 0.00 1.63 0.57
81 INT131810 Nfkb1 Negative_regulation of Localization of Apex1 1 0.01 0.52 0.57
82 INT28119 Atm Negative_regulation of Cck 1 0.42 0 0.56
83 INT142868 YY1 Positive_regulation of Oprd1 1 0.01 0.1 0.55
84 INT57546 Binding of YY1 and GNPTAB 1 0.00 0 0.53
85 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
86 INT164265 TGM7 Negative_regulation of CDK2 1 0.26 1.08 0.53
87 INT160779 Cps1 Positive_regulation of ATM 1 0.01 0.94 0.53
88 INT240192 RBX1 Negative_regulation of BDNF 1 0.08 0.13 0.52
89 INT177504 Gabrg1 Positive_regulation of PCNA 1 0.07 0.22 0.52
90 INT135500 Positive_regulation of YY1 Positive_regulation of MRGPRX4 1 0.01 0.06 0.52
91 INT135501 MRGPRX4 Positive_regulation of YY1 1 0.00 0.06 0.52
92 INT135497 YY1 Positive_regulation of MRGPRX4 1 0.01 0.06 0.52
93 INT140841 Il24 Positive_regulation of Gene_expression of GADD45G 1 0.25 1.21 0.51
94 INT305851 Polk Positive_regulation of Gene_expression of Tslp 1 0.29 0.9 0.51
95 INT202957 CPP Negative_regulation of MCRS1 1 0.14 1.53 0.51
96 INT135503 MRGPRX4 Regulation of YY1 1 0.01 0.05 0.5
97 INT72525 Positive_regulation of TCEA1 Positive_regulation of Pomc 1 0.08 0 0.5
98 INT322048 Prkdc Negative_regulation of Col7a1 1 0.00 0.45 0.5
99 INT184405 CRP Positive_regulation of Gene_expression of ASF1A 1 0.03 1.17 0.49
100 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
101 INT132060 NBN Positive_regulation of Nos2 1 0.01 0.21 0.49
102 INT65185 Binding of ATRX and Ssr1 1 0.03 1.68 0.49
103 INT155921 PARP1 Positive_regulation of Gene_expression of IL6 1 0.49 0.44 0.48
104 INT72524 Positive_regulation of TCEA1 Positive_regulation of Localization of Pomc 1 0.08 0 0.48
105 INT34006 Binding of ITPR3 and YY1 1 0.22 0.33 0.48
106 INT58578 Binding of RPA1 and TACR1 1 0.01 0 0.48
107 INT202969 Positive_regulation of SGSM3 Positive_regulation of MCRS1 1 0.02 1.22 0.47
108 INT202964 SGSM3 Positive_regulation of MCRS1 1 0.03 1.21 0.47
109 INT338086 PYCARD Positive_regulation of TCEA1 1 0.10 0 0.47
110 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46
111 INT88080 Binding of Chrna4 and Psmb6 1 0.03 0.56 0.46
112 INT72203 GH1 Regulation of OGG1 1 0.10 0 0.46
113 INT95276 Obfc2a Negative_regulation of Nos3 1 0.02 1.02 0.46
114 INT168130 Mir190 Positive_regulation of Phosphorylation of Yy1 1 0.54 0 0.45
115 INT128521 Binding of YY1 and IGKV2-26 1 0.12 0 0.45
116 INT168131 Phosphorylation of Yy1 Positive_regulation of Gene_expression of Mir190 1 0.32 0 0.45
117 INT227495 Regulation of Binding of TCEA1 and SIRT2 1 0.01 0.45 0.45
118 INT168129 Binding of Yy1 and Positive_regulation of Transcription of Tln2 1 0.02 0 0.44
119 INT8356 Binding of YY1 and Smpd1 1 0.32 0 0.43
120 INT168132 Binding of Yy1 and Tln2 1 0.01 0 0.43
121 INT240193 RBX1 Positive_regulation of Gene_expression of BDNF 1 0.10 0 0.43
122 INT20221 Binding of Grcc10 and Fbxo6 1 0.00 0 0.42
123 INT121378 Fancl Positive_regulation of MIF 1 0.01 0.92 0.42
124 INT62066 Binding of YY1 and Pdyn 1 0.00 0 0.42
125 INT343916 Hspa1a Positive_regulation of Gene_expression of TNF 1 0.16 1.17 0.41
126 INT343919 Hspa1a Positive_regulation of Gene_expression of IL6 1 0.02 1.17 0.4
127 INT343907 Hspa1a Positive_regulation of Gene_expression of Cxcl2 1 0.01 1.17 0.4
128 INT7636 RFC1 Negative_regulation of Localization of Oxt 1 0.14 0 0.39
129 INT13715 PDYN Positive_regulation of TYMS 1 0.27 0 0.39
130 INT7634 RFC1 Negative_regulation of Localization of AVP 1 0.46 0 0.39
131 INT263433 Abl1 Regulation of Abl1 1 0.04 0.28 0.38
132 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36
133 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
134 INT305853 Polk Regulation of Gene_expression of Hand2 1 0.12 0.93 0.35
135 INT305856 Polk Regulation of Gene_expression of TH1L 1 0.43 0.93 0.35
136 INT344238 MCRS1 Regulation of TREX1 1 0.08 1.02 0.34
137 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34
138 INT175552 Binding of CASR and UPF1 1 0.01 0.89 0.33
139 INT214987 Binding of FANCC and Sigmar1 1 0.06 0.34 0.32
140 INT253766 Binding of Apex1 and Tlr4 1 0.03 0.53 0.32
141 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32
142 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
143 INT35963 Binding of ALB and MPG 1 0.40 0 0.3
144 INT281797 Positive_regulation of Chrna4 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.43 0.3
145 INT56250 Binding of NBN and NCOR2 1 0.00 0 0.3
146 INT121186 Binding of Msh3 and Em 1 0.02 0.1 0.3
147 INT130107 YY1 Positive_regulation of MAPK1 1 0.45 0 0.28
148 INT18499 Binding of SUMO1 and SEC1 1 0.12 0 0.28
149 INT130106 Regulation of YY1 Positive_regulation of MAPK1 1 0.41 0 0.28
150 INT29914 FANCB Negative_regulation of Binding of Pomc 1 0.01 0 0.27
151 INT305849 Polk Positive_regulation of Gene_expression of Hand2 1 0.08 0.76 0.27
152 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
153 INT237919 BAX Positive_regulation of Protein_catabolism of PARP1 1 0.03 1.41 0.26
154 INT125514 Positive_regulation of PRKDC Positive_regulation of Positive_regulation of NFKB1 1 0.07 0.44 0.26
155 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26
156 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
157 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26
158 INT156156 Positive_regulation of Binding of NGF and SMG1 1 0.03 0.41 0.26
159 INT305854 Polk Regulation of Gene_expression of Atp11c 1 0.05 0.73 0.26
160 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
161 INT243640 Binding of Twist1 and Stub1 1 0.08 0.34 0.24
162 INT281798 CFD Regulation of Positive_regulation of Chrna4 1 0.01 0.24 0.24
163 INT253765 Apex1 Positive_regulation of Hmgb1 1 0.09 1.27 0.24
164 INT287101 Binding of Bdnf and Mutyh 1 0.04 0.58 0.24
165 INT156157 Binding of NGF and SMG1 1 0.02 0.4 0.23
166 INT151884 Binding of PRLR and YY1 1 0.01 0 0.23
167 INT61346 Positive_regulation of YY1 Positive_regulation of Localization of SST 1 0.54 0 0.22
168 INT341378 Positive_regulation of Ros1 Positive_regulation of Parp1 1 0.01 1.08 0.22
169 INT305850 Polk Positive_regulation of Gene_expression of dp 1 0.07 0.64 0.21
170 INT64382 Positive_regulation of Binding of YY1 and Tyr 1 0.11 0 0.21
171 INT297965 MAPK14 Negative_regulation of GADD45A 1 0.05 1 0.21
172 INT331602 Binding of SSRP1 and Tlr4 1 0.03 0.9 0.21
173 INT81159 Binding of PARP1 and IgG-2a 1 0.00 1.02 0.21
174 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21
175 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
176 INT277318 Upf1 Positive_regulation of Atxn8os 1 0.01 0.77 0.21
177 INT322017 RPA1 Positive_regulation of IL1B 1 0.00 0 0.21
178 INT64383 Binding of YY1 and Tyr 1 0.09 0 0.21
179 INT159132 Klf9 Positive_regulation of Smc5 1 0.01 0.48 0.2
180 INT132054 NBN Positive_regulation of NOS1 1 0.00 0.08 0.2
181 INT39318 Binding of MPG and PTAFR 1 0.54 0.36 0.2
182 INT68510 Binding of ATM and PRLR 1 0.01 0 0.19
183 INT168828 Binding of DDB1 and UBR1 1 0.00 0.67 0.19
184 INT28432 ADRA1D Positive_regulation of MPG 1 0.54 0.2 0.19
185 INT305848 Polk Positive_regulation of dp 1 0.09 0 0.19
186 INT79206 Binding of MGP and YY1 1 0.34 0 0.19
187 INT91862 RPA1 Negative_regulation of Transcription of ATG9B 1 0.03 0.46 0.19
188 INT179158 ATM Regulation of Gene_expression of GOPC 1 0.01 0 0.18
189 INT58579 Binding of INSRR and RPA1 1 0.00 0 0.18
190 INT179163 ATM Regulation of Gene_expression of IL13 1 0.01 0 0.18
191 INT179161 ATM Regulation of Gene_expression of IL6 1 0.02 0 0.18
192 INT179162 ATM Regulation of Gene_expression of IL8 1 0.01 0 0.18
193 INT74600 Negative_regulation of YY1 Negative_regulation of ADCY1 1 0.36 0.25 0.17
194 INT161144 MPG Regulation of Gene_expression of COMMD3 1 0.14 0 0.17
195 INT161143 MPG Regulation of ALB 1 0.16 0 0.17
196 INT305857 Polk Regulation of Gene_expression of IFN1@ 1 0.31 0.74 0.17
197 INT161146 MPG Regulation of OXA1L 1 0.27 0 0.17
198 INT245332 ATR Regulation of IL6 1 0.03 0.35 0.17
199 INT310303 Serpina10 Positive_regulation of Hspa1a 1 0.02 0.53 0.16
200 INT305846 Polk Positive_regulation of Gene_expression of Il4 1 0.13 0.24 0.15

Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA repair. They are ordered first by their pain relevance and then by number of times they were reported in DNA repair. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6437 Binding of YY1 154 0.47 26.3 90.46
2 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16
3 INT48642 Positive_regulation of TCEA1 92 0.70 24.59 53.64
4 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06
5 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36
6 INT6717 Negative_regulation of YY1 45 0.57 15.35 27.8
7 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44
8 INT3359 Regulation of YY1 32 0.60 8.19 19.2
9 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42
10 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78
11 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29
12 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94
13 INT18647 Localization of YY1 16 0.78 4.04 9.77
14 INT71494 Positive_regulation of Hspa1b 14 0.67 8.5 9.19
15 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98
16 INT49866 Negative_regulation of Parp1 53 0.58 35.37 8.84
17 INT113845 Protein_catabolism of PARP1 54 0.88 43.86 8.77
18 INT175554 Binding of MCRS1 21 0.23 25.2 8.59
19 INT123813 Positive_regulation of Parp1 74 0.70 65.36 8.56
20 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78
21 INT162393 Gene_expression of SMUG1 58 0.75 38.78 7.7
22 INT72523 Regulation of TCEA1 18 0.45 3.19 7.6
23 INT33419 Positive_regulation of Gene_expression of YY1 10 0.67 4.15 7.08
24 INT88079 Gene_expression of Chrna4 20 0.76 8.52 6.98
25 INT25647 Negative_regulation of Binding of YY1 10 0.57 1.47 6.77
26 INT42132 Negative_regulation of TCEA1 13 0.51 4.12 6.28
27 INT73179 Gene_expression of Hspa1b 10 0.73 6.24 6.04
28 INT42133 Gene_expression of TCEA1 17 0.60 5.61 5.55
29 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
30 INT12412 Binding of MPG 21 0.47 3.92 4.94
31 INT131808 Localization of Apex1 2 0.16 13.46 4.61
32 INT52203 Negative_regulation of Positive_regulation of TCEA1 5 0.51 3.27 4.48
33 INT58435 Gene_expression of Hspa1a 19 0.78 15.35 4.45
34 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39
35 INT19449 Binding of FANCB 22 0.47 7.4 4.27
36 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
37 INT59836 Positive_regulation of Upf1 24 0.02 4.42 3.99
38 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96
39 INT73750 Regulation of Gene_expression of YY1 7 0.44 0.28 3.91
40 INT94303 Gene_expression of Upf1 44 0.04 11.62 3.87
41 INT48643 Regulation of Positive_regulation of TCEA1 6 0.53 1.94 3.83
42 INT10992 Gene_expression of PARP1 32 0.76 22.22 3.74
43 INT181249 Binding of TCEA1 8 0.32 2.12 3.66
44 INT53891 Positive_regulation of Positive_regulation of YY1 5 0.49 0.24 3.65
45 INT26891 Gene_expression of OGG1 21 0.74 2.08 3.64
46 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57
47 INT19538 Positive_regulation of MPG 8 0.67 3.21 3.57
48 INT104705 Regulation of Msh3 4 0.28 0.1 3.51
49 INT29356 Positive_regulation of Binding of YY1 8 0.67 0.22 3.49
50 INT99348 Negative_regulation of PARP1 38 0.58 30.96 3.36
51 INT184894 Localization of MCRS1 9 0.47 10.04 3.31
52 INT104708 Gene_expression of Msh3 6 0.72 0.07 3.17
53 INT155091 Localization of PARP1 15 0.63 13.34 3.15
54 INT107962 Gene_expression of Pttg1 34 0.53 34.05 3.11
55 INT138319 Positive_regulation of Rpa1 3 0.07 2.75 3.07
56 INT53889 Negative_regulation of Positive_regulation of YY1 6 0.41 0.57 3.05
57 INT123815 Gene_expression of Parp1 42 0.67 27.82 3.02
58 INT82719 Positive_regulation of ASF1A 2 0.08 9.55 3
59 INT305617 Positive_regulation of Gene_expression of MCRS1 1 0.05 7.16 2.91
60 INT53890 Transcription of YY1 8 0.67 1.53 2.88
61 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81
62 INT121493 Gene_expression of XRCC1 55 0.65 73.43 2.76
63 INT73175 Positive_regulation of Gene_expression of Hspa1b 3 0.48 2.53 2.72
64 INT221269 Binding of BRCA1 14 0.40 31.77 2.7
65 INT200963 Regulation of UPF1 10 0.01 2.18 2.67
66 INT163359 Gene_expression of RFC1 9 0.65 3.34 2.64
67 INT181250 Localization of TCEA1 6 0.75 1.54 2.61
68 INT168116 Phosphorylation of Yy1 1 0.71 0 2.57
69 INT59709 Negative_regulation of Negative_regulation of YY1 3 0.57 0.07 2.55
70 INT303796 Gene_expression of Tdp1 1 0.77 70.15 2.55
71 INT75813 Positive_regulation of Positive_regulation of TCEA1 1 0.50 1.28 2.49
72 INT213681 Gene_expression of TYMS 9 0.33 8.96 2.45
73 INT139556 Positive_regulation of Chrna4 10 0.25 4.52 2.36
74 INT108148 Positive_regulation of Prkdc 2 0.16 0.49 2.31
75 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3
76 INT97973 Positive_regulation of XRCC1 24 0.40 30.95 2.26
77 INT101572 Negative_regulation of Gene_expression of PCNA 24 0.53 13.87 2.21
78 INT117415 Negative_regulation of LIG4 4 0.04 1.59 2.17
79 INT120650 Negative_regulation of UPF1 14 0.02 6.86 2.14
80 INT163833 Positive_regulation of Localization of PARP1 7 0.28 7.54 2.14
81 INT16656 Negative_regulation of Gene_expression of YY1 8 0.57 2.62 2.12
82 INT155928 Positive_regulation of Gene_expression of PARP1 13 0.68 6.54 2.1
83 INT123253 Localization of Chrna4 4 0.44 1.31 1.99
84 INT100046 Gene_expression of BTG2 16 0.20 10.81 1.95
85 INT12413 Gene_expression of MPG 11 0.76 3.13 1.94
86 INT184410 Gene_expression of ASF1A 6 0.11 5.51 1.94
87 INT148702 Positive_regulation of UPF1 29 0.31 12.9 1.91
88 INT58438 Positive_regulation of Hspa1a 8 0.68 6.24 1.91
89 INT153800 Positive_regulation of Protein_catabolism of PARP1 18 0.49 16.16 1.89
90 INT10993 Regulation of PARP1 4 0.26 2.04 1.89
91 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87
92 INT253756 Gene_expression of Apex1 1 0.14 7.47 1.84
93 INT213676 Negative_regulation of Gene_expression of TYMS 2 0.08 1.95 1.83
94 INT174240 Negative_regulation of TYMS 12 0.57 6.35 1.82
95 INT68952 Localization of PCNA 17 0.62 5.64 1.78
96 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78
97 INT131818 Binding of Parp1 14 0.46 8.74 1.76
98 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7
99 INT79802 Phosphorylation of YY1 2 0.80 0.07 1.7
100 INT63586 Regulation of Parp1 5 0.43 3.28 1.68
101 INT88412 Positive_regulation of CDK2 17 0.57 8.49 1.66
102 INT305832 Gene_expression of Polk 1 0.48 0.49 1.64
103 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6
104 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53
105 INT120519 Localization of XRCC1 15 0.78 17.03 1.51
106 INT18503 Binding of SUMO1 7 0.27 6.21 1.48
107 INT122449 Localization of SMUG1 10 0.67 7.97 1.47
108 INT184529 Negative_regulation of SMUG1 8 0.49 7.06 1.46
109 INT184532 Binding of SMUG1 7 0.21 5.73 1.45
110 INT59837 Regulation of Upf1 5 0.03 1.37 1.45
111 INT58581 Binding of RPA1 8 0.44 1.68 1.44
112 INT10669 Localization of Fen1 3 0.57 0.36 1.44
113 INT97053 Transcription of Parp1 3 0.66 2.04 1.43
114 INT58109 Positive_regulation of Positive_regulation of MPG 2 0.49 0.37 1.42
115 INT112597 Positive_regulation of Msh3 2 0.25 0 1.42
116 INT118155 Regulation of Positive_regulation of Prkdc 1 0.10 0.49 1.42
117 INT189948 Gene_expression of Pttg1 106 0.76 104.68 1.41
118 INT103907 Negative_regulation of Upf1 15 0.37 4.3 1.4
119 INT128322 Gene_expression of Cry1 11 0.60 1.03 1.4
120 INT48269 Negative_regulation of FANCB 16 0.56 5.34 1.38
121 INT128321 Regulation of Gene_expression of Cry1 2 0.34 0.09 1.38
122 INT121307 Gene_expression of Ercc1 4 0.73 12.69 1.37
123 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36
124 INT200979 Regulation of Gene_expression of UPF1 4 0.28 2.19 1.31
125 INT159360 Positive_regulation of SMG1 11 0.67 2.01 1.29
126 INT214983 Positive_regulation of FANCC 11 0.15 1.81 1.29
127 INT71926 Gene_expression of Smc1b 6 0.35 3.64 1.27
128 INT152255 Gene_expression of ATM 14 0.71 12.53 1.26
129 INT26890 Negative_regulation of Gene_expression of OGG1 2 0.34 0.13 1.26
130 INT958 Negative_regulation of ATRX 6 0.58 2.92 1.25
131 INT74018 Binding of XRCC1 19 0.31 24.78 1.24
132 INT200972 Positive_regulation of Gene_expression of UPF1 6 0.31 1.51 1.23
133 INT325005 Positive_regulation of Gene_expression of SMUG1 3 0.25 0.93 1.23
134 INT59200 Negative_regulation of Ube2d3 3 0.13 2.37 1.23
135 INT305616 Negative_regulation of Gene_expression of MCRS1 1 0.04 3.56 1.23
136 INT103164 Binding of UPF1 4 0.29 4.15 1.22
137 INT314186 Gene_expression of Npm1 1 0.01 1.78 1.22
138 INT125525 Positive_regulation of PRKDC 7 0.45 2.72 1.21
139 INT59708 Regulation of Negative_regulation of YY1 1 0.44 0.07 1.21
140 INT81768 Negative_regulation of Chrna4 5 0.42 1.97 1.2
141 INT100044 Regulation of BTG2 3 0.23 1.78 1.2
142 INT15896 Gene_expression of FANCB 18 0.65 6.44 1.18
143 INT79721 Positive_regulation of Gene_expression of Hspa1a 13 0.69 10.69 1.17
144 INT76305 Negative_regulation of Positive_regulation of Hspa1b 1 0.09 0.49 1.17
145 INT192807 Gene_expression of SSRP1 14 0.49 19.28 1.15
146 INT159361 Negative_regulation of Positive_regulation of SMG1 1 0.57 0.98 1.15
147 INT142950 Protein_catabolism of ERCC2 2 0.25 1.45 1.14
148 INT131475 Regulation of Hspa1b 1 0.31 2.01 1.14
149 INT107592 Gene_expression of SMG1 42 0.74 11.16 1.13
150 INT91872 Gene_expression of RPA1 9 0.77 5.28 1.12
151 INT167477 Regulation of TREX1 1 0.24 1.04 1.12
152 INT175508 Protein_catabolism of Parp1 30 0.85 30 1.09
153 INT46734 Positive_regulation of Stub1 6 0.16 1.44 1.09
154 INT11331 Positive_regulation of FANCB 5 0.49 2.23 1.09
155 INT107961 Positive_regulation of Gene_expression of Pttg1 2 0.38 11.69 1.09
156 INT74879 Regulation of MPG 6 0.44 0.8 1.08
157 INT74020 Negative_regulation of XRCC1 16 0.35 17.18 1.06
158 INT123816 Positive_regulation of Gene_expression of Parp1 9 0.50 6.64 1.04
159 INT202264 Positive_regulation of Pttg1 8 0.45 8.03 1.04
160 INT113712 Positive_regulation of Gene_expression of Msh3 2 0.43 0 1.04
161 INT106735 Phosphorylation of CDK2 11 0.79 4.03 1.02
162 INT202981 Positive_regulation of Binding of MCRS1 3 0.18 4.05 1.02
163 INT19849 Positive_regulation of Smc1b 8 0.50 4.09 1.01
164 INT131474 Regulation of Gene_expression of Hspa1b 1 0.31 1.51 1
165 INT305620 Regulation of Positive_regulation of MCRS1 1 0.17 2.48 0.99
166 INT153125 Negative_regulation of Protein_catabolism of PARP1 8 0.32 6.57 0.98
167 INT58107 Negative_regulation of MPG 2 0.41 0.92 0.98
168 INT167702 Negative_regulation of Rpa1 3 0.06 1.16 0.96
169 INT114830 Positive_regulation of Regulation of TCEA1 2 0.41 0.11 0.94
170 INT86907 Negative_regulation of MSH6 8 0.33 6.76 0.93
171 INT230779 Negative_regulation of Positive_regulation of MCRS1 2 0.04 3.78 0.92
172 INT108012 Regulation of Localization of YY1 1 0.26 0 0.91
173 INT166935 Gene_expression of Prkdc 10 0.65 3.14 0.9
174 INT959 Regulation of ATRX 5 0.47 5.04 0.89
175 INT168123 Positive_regulation of Phosphorylation of Yy1 1 0.60 0 0.89
176 INT74021 Regulation of XRCC1 15 0.44 16.91 0.88
177 INT237413 Binding of Fancd2 3 0.09 1.75 0.88
178 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87
179 INT51790 Negative_regulation of ASF1A 2 0.17 2.73 0.86
180 INT168114 Binding of Yy1 1 0.32 0 0.85
181 INT252442 Binding of RFC1 3 0.05 0.3 0.84
182 INT147616 Negative_regulation of Positive_regulation of Parp1 3 0.43 2.53 0.84
183 INT193019 Positive_regulation of Positive_regulation of SMUG1 6 0.39 4.7 0.83
184 INT182077 Positive_regulation of RFC1 3 0.07 1.65 0.81
185 INT332756 Localization of TREX1 1 0.01 0 0.81
186 INT117083 Localization of RTEL1 5 0.60 9.1 0.8
187 INT220605 Positive_regulation of Fancd2 2 0.09 0.1 0.8
188 INT237405 Positive_regulation of Binding of Fancd2 1 0.09 0 0.8
189 INT147433 Gene_expression of BRCA2 7 0.62 7.02 0.79
190 INT131384 Binding of Mutyh 5 0.26 2.41 0.78
191 INT114880 Negative_regulation of Cdk2 7 0.35 3.89 0.77
192 INT123254 Regulation of Chrna4 3 0.27 0.84 0.76
193 INT306520 Negative_regulation of Msh3 2 0.40 0.22 0.76
194 INT199573 Gene_expression of Abl1 33 0.65 20.79 0.75
195 INT241499 Binding of Abl1 23 0.47 8.86 0.75
196 INT92142 Binding of MSH2 5 0.46 5.64 0.75
197 INT252975 Positive_regulation of Gene_expression of PTTG1 36 0.28 31.96 0.74
198 INT258791 Positive_regulation of CDK1 14 0.45 5.73 0.74
199 INT125526 Gene_expression of PRKDC 5 0.58 4 0.74
200 INT206929 Negative_regulation of Gene_expression of XRCC1 4 0.25 6.14 0.74
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