GO:0006283

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Name transcription-coupled nucleotide-excision repair
Categary Process
Go Slim No
Go Link GO:0006283
Unique Molecular Interactions 93
Total Molecular Interactions 128
Total Single Events 1107
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for transcription-coupled nucleotide-excision repair. They are ordered first by their pain relevance and then by number of times they were reported for transcription-coupled nucleotide-excision repair. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT227493 Binding of TCEA1 and SIRT2 1 0.01 1.55 1.93
2 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
3 INT177504 Gabrg1 Positive_regulation of PCNA 1 0.07 0.22 0.52
4 INT72525 Positive_regulation of TCEA1 Positive_regulation of Pomc 1 0.08 0 0.5
5 INT72524 Positive_regulation of TCEA1 Positive_regulation of Localization of Pomc 1 0.08 0 0.48
6 INT58578 Binding of RPA1 and TACR1 1 0.01 0 0.48
7 INT338086 PYCARD Positive_regulation of TCEA1 1 0.10 0 0.47
8 INT227495 Regulation of Binding of TCEA1 and SIRT2 1 0.01 0.45 0.45
9 INT7636 RFC1 Negative_regulation of Localization of Oxt 1 0.14 0 0.39
10 INT7634 RFC1 Negative_regulation of Localization of AVP 1 0.46 0 0.39
11 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
12 INT322017 RPA1 Positive_regulation of IL1B 1 0.00 0 0.21
13 INT91862 RPA1 Negative_regulation of Transcription of ATG9B 1 0.03 0.46 0.19
14 INT58579 Binding of INSRR and RPA1 1 0.00 0 0.18
15 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
16 INT184953 Binding of CDC6 and PCNA 1 0.05 0.19 0.13
17 INT166785 NSMAF Negative_regulation of Gene_expression of PCNA 1 0.30 1.26 0.08
18 INT227836 Binding of ERCC6 and GPER 1 0.21 0.27 0.08
19 INT308831 Binding of RFC1 and IGKV2D-29 1 0.02 0 0.06
20 INT176224 Binding of CDKN1A and PCNA 4 0.08 2.52 0.03
21 INT326051 Csf2 Positive_regulation of PCNA 1 0.04 0.17 0.03
22 INT326052 Epo Positive_regulation of PCNA 1 0.04 0.17 0.03
23 INT219412 CDK2 Regulation of PCNA 1 0.20 0.11 0
24 INT189375 Rpa1 Regulation of ERCC6 1 0.04 0.05 0
25 INT227830 CSH1 Regulation of ERCC6 1 0.11 0 0
26 INT227837 Positive_regulation of Binding of CSH1 and ERCC6 1 0.20 0.15 0
27 INT330697 PCNA Regulation of INCENP 1 0.00 0.3 0
28 INT189373 Rpa1 Negative_regulation of ERCC6 1 0.03 0 0
29 INT326017 Binding of PCNA and HCC 1 0.00 0.99 0
30 INT219405 CCNF Regulation of PCNA 1 0.20 0.11 0
31 INT217779 POLR2B Regulation of Gene_expression of RASGRP1 1 0.01 0.2 0
32 INT219417 CCNA2 Regulation of PCNA 1 0.10 0.11 0
33 INT217785 POLR2B Regulation of Gene_expression of MAP3K3 1 0.06 0.2 0
34 INT227829 CFC1 Positive_regulation of Gene_expression of ERCC6 1 0.03 0 0
35 INT218976 Dlst Positive_regulation of Gene_expression of PCNA 1 0.05 0.06 0
36 INT227838 Binding of ERCC6 and PGBD3 1 0.40 0.23 0
37 INT285772 ERCC1 Positive_regulation of Binding of RAD51 1 0.05 0 0
38 INT189330 PPA1 Positive_regulation of ERCC6 1 0.10 0 0
39 INT227832 Binding of CSH1 and ERCC6 1 0.15 0.15 0
40 INT330698 PCNA Regulation of RB1 1 0.00 0.3 0
41 INT227841 PGBD1 Positive_regulation of ERCC6 1 0.44 0.29 0
42 INT338970 Binding of ING1 and PCNA 1 0.11 0.98 0
43 INT283062 ERCC8 Positive_regulation of CFH 1 0.02 1.88 0
44 INT315169 Egfr Negative_regulation of PCNA 1 0.03 0.84 0
45 INT219407 Binding of ESR1 and PCNA 1 0.31 0.31 0
46 INT285771 ERCC1 Regulation of Binding of RAD51 1 0.05 0 0
47 INT189333 CSNK2A1 Positive_regulation of Phosphorylation of ERCC6 1 0.10 0 0
48 INT227833 Positive_regulation of CFC1 Positive_regulation of Gene_expression of ERCC6 1 0.03 0 0
49 INT315170 Erbb2 Negative_regulation of PCNA 1 0.03 0.84 0
50 INT149429 ERCC2 Negative_regulation of Localization of IL8 1 0.05 0.38 0
51 INT188272 Binding of KITLG and PCNA 1 0.01 0.17 0
52 INT238394 Binding of PCNA and SRA1 1 0.00 0.07 0
53 INT227840 Binding of ERCC2 and ERCC6 1 0.11 0.66 0
54 INT149431 ERCC2 Negative_regulation of Localization of Il6 1 0.14 0.2 0
55 INT227831 Binding of ERCC2 and PGBD3 1 0.07 0.23 0
56 INT352860 Positive_regulation of POLR2B Positive_regulation of Positive_regulation of IKBKAP 1 0.03 0.74 0
57 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0
58 INT219422 CCNE2 Regulation of PCNA 1 0.10 0.11 0
59 INT238391 ELANE Positive_regulation of PCNA 1 0.01 0.07 0
60 INT227843 Binding of ERCC6 and MLL 1 0.00 0.34 0
61 INT189331 PPA1 Negative_regulation of Phosphorylation of ERCC6 1 0.06 0 0
62 INT177783 Binding of HDAC1 and PCNA 1 0.09 0.5 0
63 INT149432 ERCC2 Regulation of Localization of Il6 1 0.15 1.06 0
64 INT149428 ERCC2 Regulation of Localization of IL8 1 0.05 0.53 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for transcription-coupled nucleotide-excision repair. They are ordered first by their pain relevance and then by number of times they were reported in transcription-coupled nucleotide-excision repair. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48642 Positive_regulation of TCEA1 92 0.70 24.59 53.64
2 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42
3 INT72523 Regulation of TCEA1 18 0.45 3.19 7.6
4 INT42132 Negative_regulation of TCEA1 13 0.51 4.12 6.28
5 INT42133 Gene_expression of TCEA1 17 0.60 5.61 5.55
6 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
7 INT52203 Negative_regulation of Positive_regulation of TCEA1 5 0.51 3.27 4.48
8 INT48643 Regulation of Positive_regulation of TCEA1 6 0.53 1.94 3.83
9 INT181249 Binding of TCEA1 8 0.32 2.12 3.66
10 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57
11 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81
12 INT163359 Gene_expression of RFC1 9 0.65 3.34 2.64
13 INT181250 Localization of TCEA1 6 0.75 1.54 2.61
14 INT75813 Positive_regulation of Positive_regulation of TCEA1 1 0.50 1.28 2.49
15 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3
16 INT101572 Negative_regulation of Gene_expression of PCNA 24 0.53 13.87 2.21
17 INT68952 Localization of PCNA 17 0.62 5.64 1.78
18 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78
19 INT58581 Binding of RPA1 8 0.44 1.68 1.44
20 INT142950 Protein_catabolism of ERCC2 2 0.25 1.45 1.14
21 INT91872 Gene_expression of RPA1 9 0.77 5.28 1.12
22 INT114830 Positive_regulation of Regulation of TCEA1 2 0.41 0.11 0.94
23 INT252442 Binding of RFC1 3 0.05 0.3 0.84
24 INT182077 Positive_regulation of RFC1 3 0.07 1.65 0.81
25 INT40476 Negative_regulation of RFC1 5 0.18 2.85 0.72
26 INT130385 Gene_expression of ERCC6 7 0.77 8.36 0.63
27 INT252443 Regulation of RFC1 1 0.03 0.35 0.59
28 INT169957 Transcription of PCNA 7 0.34 0.94 0.55
29 INT176264 Binding of PCNA 21 0.21 9.08 0.51
30 INT134070 Binding of ERCC2 3 0.27 0.76 0.51
31 INT241674 Negative_regulation of Transcription of PCNA 1 0.11 0.33 0.47
32 INT130141 Phosphorylation of POLR2B 1 0.29 0.57 0.47
33 INT139399 Regulation of Gene_expression of PCNA 14 0.56 6.06 0.43
34 INT103901 Regulation of ERCC2 1 0.23 0.51 0.4
35 INT219001 Gene_expression of ERCC1 12 0.54 3.77 0.38
36 INT58580 Positive_regulation of Binding of RPA1 2 0.43 0 0.38
37 INT139391 Regulation of PCNA 10 0.60 3.12 0.33
38 INT118955 Phosphorylation of PCNA 4 0.29 1.54 0.33
39 INT229244 Positive_regulation of Gene_expression of RFC1 1 0.09 0.07 0.3
40 INT189346 Positive_regulation of ERCC6 6 0.60 3.37 0.23
41 INT40477 Negative_regulation of Negative_regulation of RFC1 1 0.18 0.4 0.22
42 INT227876 Transcription of ERCC6 1 0.68 1.87 0.17
43 INT189355 Phosphorylation of ERCC6 1 0.79 1.11 0.16
44 INT91870 Negative_regulation of Gene_expression of RPA1 1 0.58 0.4 0.16
45 INT91871 Transcription of RPA1 1 0.69 0.38 0.15
46 INT91866 Positive_regulation of Gene_expression of RPA1 1 0.69 0.38 0.15
47 INT182408 Localization of ERCC6 4 0.72 2.31 0.14
48 INT238422 Positive_regulation of Positive_regulation of PCNA 4 0.20 2.92 0.13
49 INT226076 Regulation of RPA1 1 0.25 0.43 0.1
50 INT151702 Binding of ERCC6 6 0.37 1.47 0.09
51 INT194320 Localization of RPA1 2 0.06 0.17 0.09
52 INT227880 Positive_regulation of Transcription of ERCC6 1 0.50 0.52 0.09
53 INT285813 Negative_regulation of ERCC1 13 0.30 2.03 0.08
54 INT182074 Negative_regulation of Gene_expression of RFC1 1 0.03 0.76 0.08
55 INT200136 Negative_regulation of ERCC2 1 0.37 1.91 0.07
56 INT93917 Transcription of TCEA1 1 0.13 0 0.05
57 INT273404 Positive_regulation of Localization of PCNA 2 0.36 0.09 0.03
58 INT175888 Gene_expression of POLR2B 2 0.04 0.32 0.03
59 INT266166 Negative_regulation of RPA1 2 0.08 1.65 0.03
60 INT306289 Regulation of Positive_regulation of PCNA 1 0.06 0.07 0.03
61 INT291906 Positive_regulation of Negative_regulation of ERCC2 1 0.40 0 0.03
62 INT141562 Negative_regulation of ERCC6 11 0.50 3.04 0
63 INT141563 Regulation of ERCC6 6 0.59 2.54 0
64 INT298408 Transcription of POLR2B 3 0.12 2.78 0
65 INT175893 Regulation of POLR2B 2 0.08 1.34 0
66 INT169956 Positive_regulation of Transcription of PCNA 2 0.10 0.09 0
67 INT238425 Negative_regulation of Positive_regulation of PCNA 2 0.05 1.39 0
68 INT227856 Regulation of Transcription of ERCC6 1 0.45 0 0
69 INT93632 Negative_regulation of Gene_expression of TCEA1 1 0.14 0.09 0
70 INT189352 Negative_regulation of Gene_expression of ERCC6 1 0.36 0 0
71 INT175901 Negative_regulation of POLR2B 1 0.00 0.34 0
72 INT299146 Positive_regulation of RPA1 1 0.01 0.15 0
73 INT189345 Negative_regulation of Localization of ERCC6 1 0.41 0.06 0
74 INT298404 Regulation of Transcription of POLR2B 1 0.05 1.02 0
75 INT285815 Binding of ERCC1 1 0.26 0 0
76 INT285814 Positive_regulation of ERCC1 1 0.35 0.14 0
77 INT189344 Positive_regulation of Phosphorylation of ERCC6 1 0.58 0 0
78 INT189354 Negative_regulation of Phosphorylation of ERCC6 1 0.49 0 0
79 INT352861 Positive_regulation of Transcription of POLR2B 1 0.04 0.73 0
80 INT189358 Negative_regulation of Regulation of ERCC6 1 0.36 0 0
81 INT346970 Binding of POLR2B 1 0.03 0.36 0
82 INT227866 Positive_regulation of Regulation of ERCC6 1 0.50 0.58 0
83 INT189357 Positive_regulation of Binding of ERCC6 1 0.42 0.15 0
84 INT352872 Positive_regulation of POLR2B 1 0.05 0.72 0
85 INT216318 Localization of RFC1 1 0.01 0.26 0
86 INT149430 Localization of ERCC2 1 0.43 0.76 0
87 INT227883 Positive_regulation of Gene_expression of ERCC6 1 0.60 0.4 0
88 INT285819 Negative_regulation of Negative_regulation of ERCC1 1 0.30 0.18 0
89 INT150198 Gene_expression of ERCC8 1 0.09 0.12 0
90 INT227879 Regulation of Protein_catabolism of ERCC6 1 0.27 0.38 0
91 INT189356 Regulation of Regulation of ERCC6 1 0.59 0 0
92 INT252988 Negative_regulation of Binding of PCNA 1 0.06 1.25 0
93 INT150197 Regulation of ERCC8 1 0.03 0.13 0
94 INT288825 Positive_regulation of Binding of PCNA 1 0.06 1.29 0
95 INT189361 Regulation of Phosphorylation of ERCC6 1 0.38 0.07 0
96 INT227875 Protein_catabolism of ERCC6 1 0.65 0.81 0
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