GO:0006352

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Name transcription initiation, DNA-dependent
Categary Process
Go Slim No
Go Link GO:0006352
Unique Molecular Interactions 117
Total Molecular Interactions 222
Total Single Events 782
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for transcription initiation, DNA-dependent. They are ordered first by their pain relevance and then by number of times they were reported for transcription initiation, DNA-dependent. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
2 INT116269 Binding of Myc and Mycbp2 1 0.19 0.5 0.87
3 INT125568 Binding of Casr and Ncoa6 3 0.50 1.13 0.46
4 INT125567 Ncoa6 Positive_regulation of Casr 1 0.52 0.46 0.3
5 INT327300 Binding of Hnrnpd and Myc 1 0.12 1.02 0.25
6 INT213813 Binding of Tcf4 and Tfeb 1 0.14 0.81 0.24
7 INT213805 Binding of Tcf12 and Tcf4 1 0.00 0.79 0.23
8 INT225607 Ncoa6 Regulation of Gene_expression of Casr 1 0.15 0.68 0.17
9 INT116268 Binding of Myc and Acsl1 1 0.08 0.19 0.16
10 INT225608 Ppara Regulation of Ncoa6 1 0.27 0.44 0.14
11 INT201722 Myc Regulation of Gene_expression of Ccnd1 1 0.03 0.79 0.13
12 INT320261 Binding of Myc and Ntrk2 1 0.01 0.36 0.13
13 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
14 INT339116 CNA1 Regulation of RSF1 1 0.00 0.3 0.13
15 INT136880 Pebp1 Positive_regulation of Localization of Ncoa6 1 0.33 0.06 0.13
16 INT173200 PPA1 Positive_regulation of Myc 1 0.08 0.5 0.12
17 INT136876 Ncoa6 Regulation of Localization of Casr 1 0.62 0 0.12
18 INT216943 Rtf1 Regulation of Localization of Il10 1 0.02 0.35 0.09
19 INT221653 Binding of Myc and Gopc 2 0.12 0.51 0.08
20 INT67243 Ncoa6 Positive_regulation of Localization of Ins1 1 0.22 0.1 0.08
21 INT136875 Pebp1 Regulation of Localization of Ncoa6 1 0.37 0 0.06
22 INT136881 Ncoa6 Regulation of Pebp1 1 0.22 0 0.06
23 INT136879 Ncoa6 Regulation of Localization of Pebp1 1 0.37 0 0.06
24 INT125570 Ncoa6 Positive_regulation of Nr1i3 1 0.12 0 0.05
25 INT284449 Il11 Positive_regulation of TCF4 1 0.00 0.42 0.05
26 INT253023 Binding of PTTG1 and Myc 1 0.16 0.22 0.04
27 INT225556 Binding of Ncoa6 and Cytip 1 0.12 1.7 0.04
28 INT175083 TAF6L Regulation of Gene_expression of PENK 1 0.00 0.05 0.04
29 INT302291 Positive_regulation of EGFR Positive_regulation of Myc 1 0.18 1.3 0.04
30 INT225569 Binding of Ncoa6 and Ep300 1 0.18 0.63 0.04
31 INT202270 Pttg1 Positive_regulation of Myc 1 0.28 0.84 0.03
32 INT175946 RSF1 Positive_regulation of Positive_regulation of CASP3 1 0.01 0.41 0.03
33 INT173199 CNOT4 Regulation of Regulation of Myc 1 0.01 0.66 0.03
34 INT236720 Binding of Ctnnd2 and Tcf4 3 0.24 2.8 0
35 INT225485 Binding of Acsl1 and Ncoa6 1 0.01 0 0
36 INT225610 Ncoa6 Regulation of Rb1 1 0.03 0.21 0
37 INT225559 Binding of Esr1 and Ncoa6 1 0.18 0 0
38 INT225565 Ncoa6 Regulation of Creb1 1 0.06 0.21 0
39 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
40 INT225520 Binding of Ncoa2 and Ncoa6 1 0.05 0.11 0
41 INT225606 Ncoa6 Regulation of Atf2 1 0.05 0.21 0
42 INT225560 Ncoa6 Positive_regulation of nr 1 0.09 0 0
43 INT329898 MIRLET7C Regulation of Myc 1 0.49 0.62 0
44 INT225589 Ncoa6 Positive_regulation of Binding of nr 1 0.10 0 0
45 INT179095 Myc Positive_regulation of Gene_expression of Trp53 1 0.43 0.83 0
46 INT225505 Ncoa6 Positive_regulation of Positive_regulation of Tfrc 1 0.10 0 0
47 INT225584 Ncoa6 Negative_regulation of Gfer 1 0.04 0.2 0
48 INT225645 Binding of TAF1 and Acp5 1 0.01 0 0
49 INT225570 Ncoa6 Regulation of Sox9 1 0.16 0.72 0
50 INT225593 Ncoa6 Positive_regulation of Prkdc 1 0.02 0 0
51 INT225539 D0Nrs1 Positive_regulation of Ncoa6 1 0.03 0.37 0
52 INT225581 Binding of Emr1 and Ncoa6 1 0.01 0 0
53 INT221648 Binding of Myc and Sh2 1 0.05 0 0
54 INT315159 Erbb2 Negative_regulation of Myc 1 0.43 0.84 0
55 INT326898 Positive_regulation of Tcf4 Regulation of PLD2 1 0.26 0.33 0
56 INT220819 Myc Regulation of Transcription of Tert 1 0.44 0.1 0
57 INT260522 Binding of Myc and Prnp 1 0.30 0.35 0
58 INT326893 Binding of Tcf4 and Wnt3a 1 0.13 0 0
59 INT225500 Negative_regulation of Ncoa6 Positive_regulation of gr 1 0.09 0 0
60 INT225561 Binding of Tfrc and Ncoa6 1 0.07 0 0
61 INT260520 Binding of Myc and Scarb1 1 0.33 0.16 0
62 INT337408 Binding of TCF4 and KLF4 1 0.09 0 0
63 INT225575 Ncoa6 Positive_regulation of gr 1 0.10 0 0
64 INT326899 Tcf4 Positive_regulation of PLD2 1 0.28 0.49 0
65 INT322597 Myc Negative_regulation of Gene_expression of CFLAR 1 0.11 1.35 0
66 INT225564 Ncoa6 Regulation of Trp53 1 0.04 0.93 0
67 INT225601 Binding of D0Nrs1 and Ncoa6 1 0.04 0.84 0
68 INT225566 Ncoa6 Regulation of Stat2 1 0.14 0.21 0
69 INT225509 Negative_regulation of Binding of nr and Ncoa6 1 0.11 0.79 0
70 INT179093 Myc Positive_regulation of Vps54 1 0.02 2.31 0
71 INT326895 Binding of PLD2 and Tcf4 1 0.27 0.39 0
72 INT179094 Gene_expression of Myc Positive_regulation of Vps54 1 0.02 0.54 0
73 INT172464 Binding of Rab27a and Myc 1 0.13 0.69 0
74 INT225609 Negative_regulation of Binding of Ncoa6 and Asc2 1 0.14 0.79 0
75 INT225536 Ncoa6 Positive_regulation of Localization of Ide 1 0.02 0.41 0
76 INT225516 Ncoa6 Positive_regulation of D0Nrs1 1 0.04 0.3 0
77 INT225590 Ncoa6 Regulation of Srf 1 0.08 0.21 0
78 INT225532 Ncoa6 Regulation of Jun 1 0.03 0.21 0
79 INT326900 Tcf4 Regulation of PLD2 1 0.15 0.33 0
80 INT179090 Positive_regulation of Myc Regulation of Gene_expression of Trp53 1 0.23 0.69 0
81 INT225594 Ncoa6 Positive_regulation of Positive_regulation of Rars 1 0.28 0 0
82 INT179091 Binding of Max and Myc 1 0.16 0.52 0
83 INT225595 Ncoa6 Regulation of Nfkb1 1 0.04 0.21 0
84 INT225551 Binding of Paxip1 and Ncoa6 1 0.26 0.47 0
85 INT179096 Positive_regulation of Myc Positive_regulation of Positive_regulation of Vps54 1 0.02 1.14 0
86 INT225600 Binding of Ncoa6 and Asc2 1 0.12 0.78 0
87 INT225508 Ncoa6 Positive_regulation of Jun 1 0.13 0 0
88 INT225530 Binding of Gfer and Ncoa6 1 0.04 0.46 0
89 INT220822 Binding of Myc and LEF1 1 0.26 0.08 0
90 INT225557 Ncoa6 Positive_regulation of Pprc1 1 0.01 0.3 0
91 INT225604 Ncoa6 Positive_regulation of Positive_regulation of gr 1 0.12 0 0
92 INT225528 Ncoa6 Positive_regulation of Nfkb1 1 0.08 0 0
93 INT225515 Binding of Ncoa6 and Rbm39 1 0.14 0.26 0
94 INT220816 Tert Regulation of Myc 1 0.44 0.1 0
95 INT225558 Binding of Ncoa6 and Pprc1 1 0.01 0.47 0
96 INT220809 Tert Regulation of Regulation of Myc 1 0.32 0.25 0
97 INT326892 Tcf4 Positive_regulation of Pld1 1 0.28 0.05 0
98 INT315160 Egfr Negative_regulation of Myc 1 0.45 0.84 0
99 INT225526 Binding of Ncoa6 and Zfp335 1 0.04 0.26 0
100 INT225552 Binding of nr and Ncoa6 1 0.09 1.04 0
101 INT326902 Binding of HNF4A and Tcf4 1 0.02 0.35 0
102 INT225599 Ncoa6 Negative_regulation of Paxip1 1 0.26 0.2 0
103 INT220820 Binding of Myc and Tert 1 0.26 0.19 0
104 INT287874 Binding of TCF4 and TP53 1 0.02 0.54 0
105 INT352620 Gnb5 Positive_regulation of Gene_expression of Myc 1 0.01 1.09 0
106 INT179097 Binding of Myc and Vps54 1 0.01 2.42 0
107 INT225602 Positive_regulation of Binding of Ncoa6 and Cytip 1 0.17 0 0
108 INT303168 Binding of Myc and Dlgap1 1 0.10 0 0
109 INT225598 Binding of Set and Ncoa6 1 0.10 0.26 0
110 INT225625 Binding of MED23 and Ncoa6 1 0.40 0.41 0
111 INT225577 Ncoa6 Positive_regulation of Localization of D0Nrs1 1 0.03 0.17 0
112 INT225527 Ncoa6 Positive_regulation of Creb1 1 0.12 0 0
113 INT225605 Binding of Ncoa6 and Positive_regulation of Esr1 1 0.25 0 0
114 INT225514 Negative_regulation of Binding of D0Nrs1 and Ncoa6 1 0.02 0 0
115 INT225499 Ncoa6 Positive_regulation of Positive_regulation of D0Nrs1 1 0.03 0 0
116 INT337406 Binding of TCF4 and TNIK 1 0.18 0 0
117 INT326897 Tcf4 Positive_regulation of Gene_expression of PLD2 1 0.26 0.41 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for transcription initiation, DNA-dependent. They are ordered first by their pain relevance and then by number of times they were reported in transcription initiation, DNA-dependent. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82
2 INT36886 Transcription of Myc 6 0.69 3.16 2.86
3 INT73460 Positive_regulation of Gene_expression of Myc 26 0.67 20.44 2.61
4 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36
5 INT116265 Binding of Myc 9 0.36 4.28 1.36
6 INT71848 Positive_regulation of Transcription of Myc 1 0.67 0.16 1.11
7 INT102070 Regulation of Gene_expression of Myc 4 0.60 2.68 0.96
8 INT17894 Regulation of Myc 10 0.60 5.65 0.93
9 INT125565 Gene_expression of Ncoa6 3 0.75 10.15 0.59
10 INT67242 Localization of Ncoa6 6 0.72 2.21 0.52
11 INT175960 Positive_regulation of RSF1 4 0.50 3.88 0.48
12 INT125559 Positive_regulation of Ncoa6 7 0.59 3.98 0.47
13 INT125566 Binding of Ncoa6 2 0.47 5.64 0.43
14 INT90354 Negative_regulation of Myc 6 0.57 4.24 0.4
15 INT234421 Binding of TCF4 13 0.18 2.3 0.37
16 INT98598 Negative_regulation of Positive_regulation of TCF4 1 0.22 0.57 0.28
17 INT98596 Positive_regulation of TCF4 3 0.26 1.13 0.27
18 INT187547 Localization of Myc 1 0.68 0.92 0.26
19 INT187548 Regulation of Transcription of Myc 1 0.44 0.68 0.26
20 INT172445 Positive_regulation of Gene_expression of Myc 58 0.70 39.62 0.25
21 INT114369 Positive_regulation of Tcf4 6 0.40 2.7 0.25
22 INT125562 Positive_regulation of Gene_expression of Ncoa6 2 0.67 4.05 0.24
23 INT239796 Binding of TAF1 1 0.01 0.33 0.23
24 INT102071 Negative_regulation of Gene_expression of Myc 8 0.57 3.5 0.22
25 INT114372 Negative_regulation of Tcf4 2 0.25 0.7 0.2
26 INT197429 Gene_expression of TCF4 6 0.33 3.8 0.18
27 INT136871 Positive_regulation of Localization of Ncoa6 1 0.47 0.08 0.18
28 INT216933 Gene_expression of Rtf1 1 0.13 0.67 0.17
29 INT114370 Negative_regulation of Positive_regulation of Tcf4 1 0.10 0.63 0.17
30 INT210249 Gene_expression of Tcf4 14 0.66 4.32 0.16
31 INT175956 Gene_expression of RSF1 3 0.49 0.94 0.13
32 INT179083 Positive_regulation of Myc 65 0.70 38.78 0.1
33 INT236704 Binding of Tcf4 3 0.28 3.3 0.1
34 INT225342 Negative_regulation of Ncoa6 1 0.49 1.75 0.1
35 INT326846 Negative_regulation of Binding of Tcf4 1 0.25 0.26 0.1
36 INT234413 Transcription of TCF4 3 0.34 1 0.09
37 INT287943 Negative_regulation of Transcription of TCF4 1 0.15 0 0.09
38 INT287918 Negative_regulation of Binding of TCF4 1 0.15 0 0.09
39 INT172453 Binding of Myc 6 0.48 2.36 0.08
40 INT179085 Regulation of Myc 6 0.28 2.83 0.06
41 INT17893 Positive_regulation of Myc 4 0.67 3.28 0.06
42 INT201778 Positive_regulation of Phosphorylation of Myc 1 0.49 1.02 0.05
43 INT201776 Phosphorylation of Myc 1 0.80 1.01 0.05
44 INT178299 Transcription of Myc 4 0.63 0.82 0.04
45 INT178287 Positive_regulation of Transcription of Myc 2 0.47 0.49 0.04
46 INT178288 Regulation of Transcription of Myc 1 0.19 0.14 0.04
47 INT332334 Regulation of Binding of Myc 1 0.44 0 0.04
48 INT179080 Positive_regulation of Positive_regulation of Myc 1 0.70 5.2 0.03
49 INT175957 Regulation of RSF1 1 0.06 0.39 0.03
50 INT175959 Negative_regulation of RSF1 1 0.05 0.38 0.03
51 INT175964 Positive_regulation of Positive_regulation of RSF1 1 0.06 0.35 0.03
52 INT179078 Regulation of Gene_expression of Myc 6 0.62 3.02 0
53 INT210244 Positive_regulation of Gene_expression of Tcf4 4 0.59 1.49 0
54 INT179079 Negative_regulation of Myc 3 0.37 1.92 0
55 INT210250 Negative_regulation of Gene_expression of Tcf4 3 0.36 0.26 0
56 INT337481 Positive_regulation of Binding of TCF4 3 0.25 0.47 0
57 INT179077 Negative_regulation of Gene_expression of Myc 3 0.59 1.36 0
58 INT179081 Negative_regulation of Positive_regulation of Myc 2 0.37 1.27 0
59 INT210257 Regulation of Tcf4 2 0.27 0.59 0
60 INT236690 Transcription of Tcf4 2 0.41 0.98 0
61 INT337480 Phosphorylation of TCF4 1 0.40 0.06 0
62 INT142711 Negative_regulation of Transcription of Myc 1 0.41 0.45 0
63 INT225415 Negative_regulation of Localization of Ncoa6 1 0.36 0.46 0
64 INT225390 Positive_regulation of Binding of Ncoa6 1 0.49 0.26 0
65 INT225387 Negative_regulation of Gene_expression of Ncoa6 1 0.41 0.76 0
66 INT260509 Localization of Myc 1 0.60 0.35 0
67 INT175962 Positive_regulation of Gene_expression of RSF1 1 0.05 0.56 0
68 INT225401 Phosphorylation of Ncoa6 1 0.79 0.43 0
69 INT179075 Positive_regulation of Binding of Myc 1 0.50 0.14 0
70 INT326839 Positive_regulation of Positive_regulation of Tcf4 1 0.29 0.4 0
71 INT292838 Gene_expression of TAF1 1 0.04 0.48 0
72 INT326841 Negative_regulation of Transcription of Tcf4 1 0.25 0 0
73 INT339169 Binding of RSF1 1 0.27 0.19 0
74 INT225425 Transcription of Ncoa6 1 0.69 1.34 0
75 INT225320 Regulation of Ncoa6 1 0.60 2.67 0
76 INT287939 Positive_regulation of Negative_regulation of TCF4 1 0.17 0.52 0
77 INT225340 Negative_regulation of Binding of Ncoa6 1 0.42 0.05 0
78 INT287916 Negative_regulation of TCF4 1 0.20 0.52 0
79 INT337485 Positive_regulation of Transcription of TCF4 1 0.25 0.26 0
80 INT210253 Regulation of Gene_expression of Tcf4 1 0.23 0.09 0
81 INT287952 Positive_regulation of Gene_expression of TCF4 1 0.17 0.69 0
82 INT225351 Regulation of Phosphorylation of Ncoa6 1 0.44 0 0
83 INT225407 Regulation of Binding of Ncoa6 1 0.44 0.16 0
84 INT172440 Negative_regulation of Binding of Myc 1 0.15 0.55 0
85 INT225343 Regulation of Positive_regulation of Ncoa6 1 0.44 0 0
86 INT179087 Regulation of Positive_regulation of Myc 1 0.45 0.8 0
87 INT236696 Positive_regulation of Transcription of Tcf4 1 0.08 0.98 0
88 INT326840 Positive_regulation of Binding of Tcf4 1 0.29 0.07 0
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