GO:0006355

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Name regulation of transcription, DNA-dependent
Categary Process
Go Slim No
Go Link GO:0006355
Unique Molecular Interactions 9926
Total Molecular Interactions 13072
Total Single Events 118907
Pain Genes Associated 878

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of transcription, DNA-dependent. They are ordered first by their pain relevance and then by number of times they were reported for regulation of transcription, DNA-dependent. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
3 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
4 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
5 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
6 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
7 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
8 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
9 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
10 INT32911 Binding of Insrr and Rbm39 2 0.00 0 3.95
11 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9
12 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
13 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81
14 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
15 INT104977 MITF Regulation of Gene_expression of MC1R 1 0.69 0.91 3.71
16 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
17 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
18 INT334928 Binding of pr and Aes 1 0.00 1.49 3.38
19 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
20 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
21 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
22 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
23 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23
24 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
25 INT202959 Binding of BAG3 and MCRS1 1 0.11 7.46 3.14
26 INT289979 Binding of Helt and Negative_regulation of Maoa 1 0.00 0.17 3.14
27 INT85042 Binding of CCT6A and MAX 1 0.00 0 3.13
28 INT94204 NCOR2 Regulation of Gene_expression of SP5 1 0.02 2.15 3.12
29 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
30 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
31 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
32 INT32656 Pomc Positive_regulation of Rbm39 1 0.08 0.42 2.84
33 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
34 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
35 INT91350 Binding of Pla2g4a and RYBP 1 0.00 1.15 2.65
36 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
37 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53
38 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
39 INT170038 Gtf3a Regulation of Gene_expression of DRGX 1 0.00 1.36 2.46
40 INT135867 Zfp821 Positive_regulation of Positive_regulation of Chrne 1 0.01 0 2.44
41 INT153728 RYBP Positive_regulation of Gpt 3 0.03 2.01 2.36
42 INT249013 Gabrg1 Negative_regulation of Per2 1 0.34 0.07 2.31
43 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
44 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
45 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
46 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
47 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
48 INT66157 Binding of ALB and BDP1 1 0.11 0 2.13
49 INT135868 Zfp821 Positive_regulation of Binding of ACAA1 1 0.00 0 2.11
50 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
51 INT133946 Binding of DNM2 and OPRK1 1 0.11 0 2.1
52 INT85041 Binding of IGHG3 and MAX 1 0.00 0 2.09
53 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
54 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
55 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
56 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06
57 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
58 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
59 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
60 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
61 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
62 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
63 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01
64 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
65 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
66 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
67 INT213973 Binding of Pax3 and Mthfd1 1 0.00 0.16 1.99
68 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
69 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
70 INT53751 Positive_regulation of Cyp2e1 Positive_regulation of RYBP 1 0.14 0.89 1.98
71 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
72 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
73 INT6320 Binding of Rbm39 and Scq1 1 0.03 0 1.92
74 INT116815 Binding of Pias1 and Ppbp 1 0.36 0.86 1.92
75 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9
76 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
77 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
78 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
79 INT113572 Binding of DMRT1 and OPRM1 1 0.01 0 1.9
80 INT129903 Nr1i2 Regulation of Cyp3a11 1 0.64 1.26 1.9
81 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89
82 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
83 INT169346 Nxn Negative_regulation of Dynll1 1 0.06 1.22 1.87
84 INT13940 DNM2 Regulation of Localization of CGA 1 0.11 0 1.86
85 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
86 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
87 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
88 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
89 INT334345 Binding of GRP and Helt 1 0.02 0 1.79
90 INT115048 Kcnip3 Regulation of Gene_expression of Pdyn 2 0.27 0.71 1.78
91 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
92 INT104710 Em Positive_regulation of Rbm39 1 0.02 0.07 1.76
93 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
94 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
95 INT104709 Msh3 Positive_regulation of Rbm39 1 0.01 0.07 1.76
96 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
97 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
98 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
99 INT142073 Binding of Helt and Nrm 1 0.00 0 1.74
100 INT157524 Binding of GRM5 and OPRM1 1 0.36 0 1.74
101 INT92369 Binding of CYP2D6 and RYBP 1 0.25 0.15 1.73
102 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
103 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
104 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71
105 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
106 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
107 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
108 INT249005 Gabrg1 Positive_regulation of Per2 1 0.39 0 1.7
109 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
110 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
111 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69
112 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
113 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
114 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
115 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66
116 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
117 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
118 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
119 INT335405 Binding of Arntl and Npas2 1 0.28 1.82 1.61
120 INT167200 Gtf3a Regulation of Gene_expression of Ngf 1 0.08 1.47 1.6
121 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
122 INT48790 Negative_regulation of Rtcd1 Negative_regulation of Pax3 1 0.02 0 1.59
123 INT149632 Binding of HK1 and NCOR2 1 0.01 0.13 1.58
124 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
125 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
126 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
127 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
128 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56
129 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
130 INT333150 Tlx2 Regulation of asa 1 0.04 2.17 1.55
131 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
132 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54
133 INT100784 RYBP Positive_regulation of CYP3A4 1 0.44 0 1.54
134 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
135 INT32657 Positive_regulation of Pomc Positive_regulation of Rbm39 1 0.08 0.22 1.51
136 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
137 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
138 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
139 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
140 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
141 INT29093 Binding of H2-Ab1 and Rbm39 1 0.06 0 1.5
142 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
143 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
144 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
145 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
146 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
147 INT276687 Pax3 Positive_regulation of Nkx1-1 1 0.00 0.59 1.47
148 INT27932 Binding of CCK and NCOR2 1 0.01 0.91 1.47
149 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
150 INT104975 MITF Regulation of Transcription of PRSS1 1 0.68 0.35 1.46
151 INT104972 MITF Regulation of Transcription of TYR 1 0.20 0.35 1.45
152 INT6976 Helt Regulation of Gene_expression of St8sia1 1 0.00 0.07 1.45
153 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
154 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
155 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44
156 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
157 INT28992 Tmpo Positive_regulation of Pomc 1 0.36 3.18 1.41
158 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
159 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
160 INT93388 Rbm39 Positive_regulation of Positive_regulation of Pdyn 1 0.03 0.32 1.4
161 INT79745 Gtf3a Positive_regulation of Positive_regulation of Sst 1 0.09 0 1.4
162 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
163 INT161189 CRX Regulation of Gene_expression of Rvm 1 0.00 2 1.39
164 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
165 INT133933 Binding of DNM2 and TP53INP2 1 0.00 0 1.38
166 INT161191 CRX Regulation of Gene_expression of Trib3 1 0.00 2 1.38
167 INT162105 Nr4a3 Regulation of ACPT-I 1 0.10 0.26 1.38
168 INT50706 Phax Positive_regulation of Localization of Trib3 1 0.04 0.28 1.38
169 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
170 INT161185 NMS Regulation of Gene_expression of Trib3 1 0.03 2 1.38
171 INT167169 Nfkb1 Regulation of Gene_expression of Crp 1 0.09 1.76 1.38
172 INT26893 OGG1 Negative_regulation of Gh1 1 0.12 0 1.37
173 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
174 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
175 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
176 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
177 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
178 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
179 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
180 INT140532 Gtf3a Positive_regulation of DYT10 1 0.12 1.83 1.34
181 INT68071 Binding of Tic1 and Rbm39 1 0.01 2.54 1.33
182 INT126831 Binding of Oprk1 and Rbm39 1 0.05 0.88 1.33
183 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
184 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
185 INT59446 Rbm39 Positive_regulation of Negative_regulation of Pomc 1 0.03 0.19 1.32
186 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
187 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
188 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
189 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
190 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
191 INT148778 Binding of Usf1 and Rtn1 1 0.40 0.85 1.3
192 INT94367 Binding of ARRB1 and TP53INP2 1 0.25 0 1.3
193 INT95406 Trib3 Positive_regulation of Ephb1 2 0.08 0.96 1.29
194 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29
195 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
196 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
197 INT85742 Pdyn Positive_regulation of Rbm39 1 0.01 0.17 1.29
198 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
199 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
200 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of transcription, DNA-dependent. They are ordered first by their pain relevance and then by number of times they were reported in regulation of transcription, DNA-dependent. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
3 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
4 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
5 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54
6 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
7 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
8 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
9 INT812 Localization of INS 1026 0.81 515.6 145.31
10 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
11 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05
12 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
13 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73
14 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
15 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
16 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06
17 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
18 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
19 INT5587 Regulation of Fos 191 0.62 40.81 99.7
20 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31
21 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
22 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
23 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28
24 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01
25 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
26 INT22967 Positive_regulation of RYBP 94 0.56 37.04 85.92
27 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
28 INT8534 Localization of Pax3 85 0.59 28.71 82.82
29 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
30 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48
31 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
32 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16
33 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
34 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
35 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47
36 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
37 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
38 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
39 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
40 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44
41 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
42 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
43 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89
44 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
45 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
46 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
47 INT18883 Negative_regulation of RYBP 53 0.56 21.14 57.52
48 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
49 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6
50 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5
51 INT5770 Binding of Rbm39 88 0.41 13.23 55.5
52 INT251 Regulation of INS 398 0.62 232.47 55.04
53 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53
54 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
55 INT122041 Binding of Ppara 308 0.48 189.17 51.48
56 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
57 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
58 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17
59 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
60 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
61 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47
62 INT4656 Localization of RYBP 49 0.77 5.28 46.21
63 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
64 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
65 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
66 INT935 Localization of Gtf3a 124 0.70 35.72 43.3
67 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9
68 INT4913 Binding of Pax3 52 0.28 9.57 42.67
69 INT11180 Binding of RYBP 52 0.46 13.86 42.53
70 INT60388 Gene_expression of Helt 90 0.07 19.18 41.72
71 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95
72 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
73 INT107576 Gene_expression of Atf3 114 0.78 72.42 38.64
74 INT18774 Gene_expression of RYBP 67 0.65 47.66 37.59
75 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
76 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
77 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
78 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
79 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94
80 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
81 INT103094 Binding of PPARA 308 0.47 177.26 34.75
82 INT1163 Negative_regulation of Rbm39 64 0.29 16.8 34.74
83 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
84 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6
85 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
86 INT95789 Positive_regulation of Grm5 42 0.55 20.1 33.72
87 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69
88 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
89 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
90 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
91 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33
92 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58
93 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
94 INT6053 Transcription of Fos 107 0.72 20.97 31.88
95 INT47764 Binding of Jun 106 0.48 22.62 31.39
96 INT6058 Localization of Fos 73 0.81 16.7 30.84
97 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36
98 INT8691 Localization of Insr 85 0.80 9.27 30.32
99 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25
100 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
101 INT15296 Regulation of Rbm39 45 0.29 10.66 29.27
102 INT5300 Regulation of Insr 54 0.60 11.33 29.26
103 INT11796 Positive_regulation of Helt 52 0.31 11.7 29.22
104 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
105 INT6855 Binding of NCOR2 71 0.41 15.64 28.96
106 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
107 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
108 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45
109 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31
110 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97
111 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
112 INT37296 Binding of Esr1 117 0.43 62.51 27.33
113 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
114 INT10799 Localization of ENG 63 0.78 18.67 27.28
115 INT51602 Gene_expression of Grm5 59 0.75 17.29 26.99
116 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67
117 INT12681 Regulation of Trib3 76 0.53 23.92 26.58
118 INT5378 Regulation of Gene_expression of Fos 47 0.60 14.47 26.41
119 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35
120 INT20462 Binding of ESR1 210 0.44 102.7 26.34
121 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
122 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
123 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74
124 INT28336 Positive_regulation of Pax3 37 0.33 20.94 25.66
125 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
126 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
127 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
128 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
129 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71
130 INT10929 Positive_regulation of FLII 46 0.67 13.17 24.63
131 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23
132 INT8518 Localization of Ifng 53 0.81 36.68 24.13
133 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65
134 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54
135 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28
136 INT18884 Regulation of RYBP 25 0.38 11.43 23.2
137 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
138 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16
139 INT71875 Localization of Nfkb1 92 0.78 48.13 22.94
140 INT129157 Positive_regulation of Atf3 48 0.69 35.42 22.87
141 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
142 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
143 INT78571 Positive_regulation of Grm5 35 0.69 11.81 22.45
144 INT127435 Gene_expression of Per1 89 0.77 13.94 22.31
145 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27
146 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19
147 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05
148 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
149 INT7573 Positive_regulation of Nr3c2 38 0.67 20 21.84
150 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6
151 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6
152 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58
153 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
154 INT5586 Binding of Fos 47 0.48 12.7 21.33
155 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25
156 INT43226 Gene_expression of Hivep3 75 0.71 30.53 21.14
157 INT52529 Regulation of Nfkb1 48 0.61 26.2 20.89
158 INT69877 Positive_regulation of Positive_regulation of Nfkb1 53 0.68 31.44 20.7
159 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
160 INT5096 Positive_regulation of Gtf3a 79 0.60 42.26 20.62
161 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
162 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48
163 INT48769 Regulation of Pdpk1 20 0.35 9.78 20.36
164 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98
165 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
166 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
167 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44
168 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
169 INT19509 Localization of Ifng 55 0.78 28.25 18.67
170 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
171 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
172 INT11275 Regulation of Fos 37 0.60 5.79 18.18
173 INT62577 Negative_regulation of Creb1 55 0.59 19.68 18.1
174 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
175 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
176 INT13244 Binding of Helt 30 0.31 4.56 18.01
177 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97
178 INT107454 Positive_regulation of Stat3 43 0.68 19.63 17.69
179 INT10555 Gene_expression of FLII 37 0.75 7.81 17.6
180 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
181 INT8526 Negative_regulation of Positive_regulation of Fos 26 0.59 5.99 17.52
182 INT70557 Negative_regulation of Localization of Pax3 1 0.36 1.15 17.32
183 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
184 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24
185 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
186 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96
187 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86
188 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
189 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
190 INT102023 Regulation of Creb1 51 0.62 16.29 16.71
191 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
192 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41
193 INT104045 Regulation of Hand1 65 0.35 51.32 16.26
194 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
195 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98
196 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95
197 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83
198 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
199 INT92354 Localization of ESR1 77 0.75 33.04 15.51
200 INT38253 Localization of Trib3 35 0.63 10.28 15.42
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