GO:0006357

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Name regulation of transcription from RNA polymerase II promoter
Categary Process
Go Slim No
Go Link GO:0006357
Unique Molecular Interactions 1579
Total Molecular Interactions 2086
Total Single Events 14766
Pain Genes Associated 196

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of transcription from RNA polymerase II promoter. They are ordered first by their pain relevance and then by number of times they were reported for regulation of transcription from RNA polymerase II promoter. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06
2 INT334928 Binding of pr and Aes 1 0.00 1.49 3.38
3 INT123451 Binding of YY1 and Adra2a 1 0.37 0 2.98
4 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
5 INT39108 Binding of PDYN and YY1 2 0.50 0.44 2.14
6 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
7 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
8 INT62065 Binding of YY1 and Penk 3 0.14 0 1.69
9 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
10 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
11 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
12 INT333150 Tlx2 Regulation of asa 1 0.04 2.17 1.55
13 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
14 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
15 INT30042 Binding of YY1 and Gnrhr 1 0.18 0 1.47
16 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
17 INT154114 PENK Positive_regulation of YY1 1 0.50 0.06 1.41
18 INT154113 POMC Positive_regulation of YY1 1 0.70 0.06 1.41
19 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4
20 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
21 INT121802 DEAF1 Negative_regulation of HTR1A 1 0.46 0.88 1.29
22 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
23 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
24 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
25 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
26 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
27 INT59707 PSENEN Regulation of Negative_regulation of YY1 1 0.12 0.07 1.21
28 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16
29 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
30 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
31 INT56882 Binding of YY1 and Ppbp 1 0.01 0 1.11
32 INT52076 Binding of RYBP and Abt1 1 0.01 0.28 1.08
33 INT100678 IL4 Positive_regulation of STAT6 1 0.49 2.63 1.08
34 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06
35 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
36 INT119887 Binding of Atf4 and Usf1 1 0.21 0.15 1.05
37 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
38 INT118859 GNA14 Positive_regulation of STAT3 1 0.01 0.38 1.03
39 INT86073 Med15 Regulation of Calca 1 0.49 0.2 1.03
40 INT154236 Binding of TBX3 and Ugt2b7 1 0.41 0.74 1
41 INT59518 YY1 Positive_regulation of SGCG 1 0.50 0.32 0.99
42 INT106248 Binding of CCR5 and YY1 1 0.54 0.19 0.98
43 INT94206 SP5 Regulation of Gene_expression of FOS 1 0.22 0.7 0.98
44 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
45 INT133076 STAT6 Positive_regulation of OPRM1 1 0.38 0 0.95
46 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
47 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
48 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
49 INT139330 Binding of SGCG and Stat1 1 0.37 0.75 0.94
50 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94
51 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
52 INT118204 ST14 Regulation of YY1 1 0.04 0 0.93
53 INT133073 IL4 Positive_regulation of Phosphorylation of STAT6 1 0.39 0 0.9
54 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9
55 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
56 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
57 INT203101 Binding of Aes and Mtx1 2 0.25 0.24 0.88
58 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
59 INT161915 Negative_regulation of Binding of POMC and YY1 1 0.33 0 0.88
60 INT30955 YY1 Negative_regulation of Negative_regulation of LH 1 0.23 0.47 0.87
61 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
62 INT104126 STAT3 Regulation of Phospho1 1 0.00 0.06 0.86
63 INT167947 Binding of STAT1 and Oprm1 1 0.00 0 0.86
64 INT124878 Gnat3 Negative_regulation of Gene_expression of FOS 1 0.09 0.16 0.85
65 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85
66 INT63594 Snai1 Negative_regulation of Binding of Ugt1a2 1 0.05 0.32 0.82
67 INT124877 Gnat3 Negative_regulation of FOS 1 0.09 0.15 0.82
68 INT124876 Gnat3 Negative_regulation of Positive_regulation of FOS 1 0.09 0.15 0.82
69 INT63596 Snai1 Negative_regulation of ITS 1 0.00 0.31 0.81
70 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 0.09 0.61 0.81
71 INT100677 IL13 Positive_regulation of STAT6 1 0.36 1.95 0.81
72 INT341367 CRX Positive_regulation of Positive_regulation of FOS 1 0.04 0.83 0.8
73 INT151882 Binding of YY1 and DLL1 1 0.00 0 0.79
74 INT151883 Negative_regulation of Binding of YY1 and DLL1 1 0.00 0 0.79
75 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
76 INT128180 Gna12 Regulation of Regulation of RHOA 1 0.00 0 0.78
77 INT118854 GNA14 Positive_regulation of Positive_regulation of STAT3 1 0.02 0.31 0.76
78 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
79 INT166672 YY1 Regulation of Binding of UGT1A6 1 0.48 0 0.76
80 INT348174 Binding of STAT3 and IL23R 1 0.40 1.9 0.76
81 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
82 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76
83 INT166674 YY1 Regulation of Binding of PRKCA 1 0.38 0 0.75
84 INT151810 JUND Positive_regulation of Positive_regulation of OPRM1 1 0.26 0 0.74
85 INT186445 Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
86 INT7049 Binding of YY1 and Oprd1 1 0.01 0 0.73
87 INT186443 Phosphorylation of Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
88 INT157541 Binding of YY1 and Regulation of Gene_expression of OPRM1 1 0.31 1.21 0.72
89 INT186444 Creb1 Regulation of FOS 1 0.49 0.43 0.72
90 INT186442 Phosphorylation of Creb1 Regulation of FOS 1 0.49 0.43 0.72
91 INT11446 BLZF1 Positive_regulation of Positive_regulation of DECR1 1 0.03 0 0.72
92 INT221938 Binding of TRPA1 and Tceb1 1 0.02 0 0.71
93 INT166671 YY1 Regulation of Positive_regulation of UGT1A6 1 0.48 0 0.7
94 INT207542 Sp1 Regulation of Oprm1 1 0.15 0.06 0.7
95 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
96 INT287099 Binding of Bdnf and T 1 0.10 1.1 0.69
97 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
98 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
99 INT133942 Binding of YY1 and ARFGEF1 1 0.05 0 0.69
100 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
101 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
102 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
103 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
104 INT133936 Binding of DNM2 and YY1 1 0.29 0 0.69
105 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
106 INT66582 Binding of FOS and Rare2 1 0.00 0.07 0.69
107 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
108 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
109 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
110 INT250871 Il1a Positive_regulation of Protein_catabolism of Ecm1 1 0.01 1.44 0.68
111 INT74599 YY1 Negative_regulation of ADCY1 2 0.36 0.31 0.67
112 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
113 INT240065 KCNIP3 Regulation of Transcription of PDYN 1 0.42 0.88 0.67
114 INT207547 Sp1 Regulation of Qsox1 1 0.05 0.06 0.67
115 INT62059 Positive_regulation of SCN5A Positive_regulation of Gene_expression of FOS 1 0.01 0.42 0.66
116 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65
117 INT101716 JUND Regulation of Regulation of OPRM1 1 0.09 0.06 0.65
118 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
119 INT226306 CHPT1 Positive_regulation of Localization of DBP 1 0.26 0.65 0.64
120 INT160119 EPO Regulation of Gene_expression of NFKB1 1 0.02 0.2 0.64
121 INT126614 Ppyr1 Negative_regulation of Phosphorylation of Stat5a 1 0.27 0.1 0.64
122 INT148773 Binding of Calca and Usf2 1 0.46 0.42 0.64
123 INT153797 NUBPL Negative_regulation of PPARD 1 0.02 0.69 0.64
124 INT89877 Pdyn Positive_regulation of Nkx2-5 1 0.11 0 0.64
125 INT114950 YY1 Positive_regulation of Positive_regulation of PPARA 1 0.52 0.25 0.64
126 INT148776 Binding of Usf2 and Rtn1 1 0.38 0.42 0.64
127 INT117007 Binding of Oprm1 and Sfpi1 1 0.50 0.07 0.63
128 INT248172 Epo Regulation of Cysltr1 1 0.01 0.74 0.63
129 INT123416 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.60 0 0.63
130 INT192332 UBR7 Negative_regulation of TXK 1 0.00 1.38 0.63
131 INT34005 YY1 Regulation of KNG1 1 0.04 0.38 0.63
132 INT135498 Binding of YY1 and MRGPRX4 1 0.00 0.2 0.62
133 INT113338 Binding of EPO and KNCN 1 0.02 1.39 0.62
134 INT148780 Binding of Usf2 and Usf1 1 0.40 0.41 0.62
135 INT2687 Negative_regulation of Binding of Thra and SGSM3 1 0.43 0.1 0.62
136 INT248170 Epo Regulation of Ltp 1 0.11 0.74 0.62
137 INT265651 Binding of ITGAL and MYCN 1 0.00 0.46 0.62
138 INT126615 Binding of Oprd1 and Stat5a 1 0.28 0.07 0.61
139 INT2686 Binding of Thra and SGSM3 1 0.36 0.1 0.61
140 INT177979 Binding of STAT3 and FOXI2 1 0.00 1.83 0.61
141 INT179850 Binding of Ecm1 and Il11 1 0.02 0 0.6
142 INT101719 PLAT Positive_regulation of NFYC 1 0.13 0.1 0.6
143 INT81916 HSF1 Positive_regulation of FOS 1 0.76 0.66 0.59
144 INT101717 PLAT Positive_regulation of JUND 1 0.17 0.1 0.59
145 INT240066 KCNIP3 Regulation of SLC8A3 1 0.39 0.73 0.59
146 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
147 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 0.05 0.05 0.59
148 INT240069 KCNIP3 Regulation of Gene_expression of PDYN 1 0.25 0.75 0.59
149 INT81918 HSF1 Negative_regulation of FOS 1 0.64 0.66 0.59
150 INT148771 Usf2 Negative_regulation of Calca 1 0.42 0.4 0.59
151 INT240070 KCNIP3 Regulation of CA2 1 0.02 0.72 0.59
152 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
153 INT109065 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.00 0 0.58
154 INT74656 YY1 Positive_regulation of Localization of IL2 1 0.07 0.09 0.58
155 INT2685 S100A6 Positive_regulation of Regulation of Thra 1 0.47 0.09 0.58
156 INT169290 CNR1 Positive_regulation of Negative_regulation of TXK 1 0.10 0.18 0.58
157 INT2684 S100A6 Regulation of Regulation of Thra 1 0.45 0.09 0.58
158 INT100681 Negative_regulation of IL13 Positive_regulation of STAT6 1 0.30 1.39 0.57
159 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56
160 INT239500 Binding of Aes and Atic 1 0.20 0.4 0.56
161 INT142868 YY1 Positive_regulation of Oprd1 1 0.01 0.1 0.55
162 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55
163 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54
164 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
165 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
166 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
167 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
168 INT353978 Lmx1b Regulation of Gene_expression of Pet1 1 0.31 0.21 0.53
169 INT57546 Binding of YY1 and GNPTAB 1 0.00 0 0.53
170 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
171 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
172 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
173 INT184111 Epo Positive_regulation of Il7 1 0.06 0.26 0.52
174 INT135500 Positive_regulation of YY1 Positive_regulation of MRGPRX4 1 0.01 0.06 0.52
175 INT135501 MRGPRX4 Positive_regulation of YY1 1 0.00 0.06 0.52
176 INT135497 YY1 Positive_regulation of MRGPRX4 1 0.01 0.06 0.52
177 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52
178 INT184088 Epo Positive_regulation of Il2 1 0.07 0.26 0.52
179 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
180 INT333168 Tlx2 Negative_regulation of Gene_expression of Vcam1 1 0.14 0.71 0.51
181 INT184096 Il7 Positive_regulation of Stat5a 1 0.07 0.26 0.51
182 INT121822 Binding of STAT3 and Olr1583 1 0.00 0.21 0.51
183 INT121821 Binding of STAT1 and Olr1583 1 0.00 0.21 0.51
184 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51
185 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
186 INT135503 MRGPRX4 Regulation of YY1 1 0.01 0.05 0.5
187 INT80627 Binding of KCNIP3 and Dre 4 0.03 0.72 0.49
188 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
189 INT117006 Sfpi1 Negative_regulation of Oprm1 1 0.39 0.29 0.49
190 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
191 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
192 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
193 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
194 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
195 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
196 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
197 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48
198 INT352031 Binding of NR3C1 and JUND 1 0.10 2.87 0.48
199 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
200 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of transcription from RNA polymerase II promoter. They are ordered first by their pain relevance and then by number of times they were reported in regulation of transcription from RNA polymerase II promoter. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
2 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
3 INT6437 Binding of YY1 154 0.47 26.3 90.46
4 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16
5 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
6 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
7 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06
8 INT6717 Negative_regulation of YY1 45 0.57 15.35 27.8
9 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95
10 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
11 INT3359 Regulation of YY1 32 0.60 8.19 19.2
12 INT107454 Positive_regulation of Stat3 43 0.68 19.63 17.69
13 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
14 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95
15 INT41558 Localization of Sp1 9 0.48 0.56 14.9
16 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66
17 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75
18 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
19 INT24082 Negative_regulation of Sp1 13 0.40 1.19 13.11
20 INT15246 Regulation of FOS 32 0.60 15.34 12.94
21 INT107875 Phosphorylation of Stat3 49 0.80 13.18 12.66
22 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
23 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
24 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
25 INT158070 Localization of Aes 23 0.65 19.93 10.9
26 INT221448 Gene_expression of CREG1 8 0.05 27.44 10.87
27 INT167964 Gene_expression of Aes 30 0.58 25.41 10.16
28 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
29 INT18647 Localization of YY1 16 0.78 4.04 9.77
30 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59
31 INT183000 Transcription of KCNIP3 4 0.62 12.89 9.59
32 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14
33 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
34 INT182995 Gene_expression of KCNIP3 19 0.69 13.28 8.81
35 INT1223 Negative_regulation of Snai1 15 0.38 2.05 8.46
36 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42
37 INT17333 Positive_regulation of Positive_regulation of FOS 17 0.67 6.06 8.4
38 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
39 INT150422 Positive_regulation of Aes 24 0.43 15.63 8
40 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
41 INT20914 Positive_regulation of Snai1 13 0.41 3.41 7.69
42 INT182976 Negative_regulation of KCNIP3 2 0.51 8.49 7.67
43 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
44 INT47848 Negative_regulation of Positive_regulation of FOS 14 0.57 3.78 7.63
45 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
46 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
47 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
48 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16
49 INT33419 Positive_regulation of Gene_expression of YY1 10 0.67 4.15 7.08
50 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
51 INT3098 Positive_regulation of Epo 46 0.70 28.27 7
52 INT264641 Binding of AES 25 0.42 18.56 6.98
53 INT60196 Binding of FOS 33 0.47 13.11 6.95
54 INT25647 Negative_regulation of Binding of YY1 10 0.57 1.47 6.77
55 INT52180 Binding of Aes 38 0.42 23.16 6.7
56 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67
57 INT5847 Transcription of FOS 31 0.69 11.11 6.41
58 INT171691 Protein_catabolism of Ecm1 31 0.20 11.57 6.38
59 INT129918 Positive_regulation of Phosphorylation of Stat3 17 0.63 5.42 6.28
60 INT3738 Regulation of Epo 25 0.61 13.73 6.18
61 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94
62 INT41604 Negative_regulation of Localization of Sp1 2 0.30 0.32 5.86
63 INT188844 Gene_expression of AES 44 0.58 33.94 5.85
64 INT179810 Protein_catabolism of Ecm1 30 0.11 18.28 5.75
65 INT206950 Positive_regulation of Atf4 14 0.45 7.02 5.71
66 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
67 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
68 INT118870 Positive_regulation of STAT1 36 0.67 26.18 5.46
69 INT117004 Gene_expression of Sfpi1 21 0.75 15.95 5.29
70 INT123422 Gene_expression of Lmx1b 18 0.78 6.93 5.17
71 INT201130 Localization of AES 31 0.63 25.45 5.12
72 INT240092 Negative_regulation of Gene_expression of KCNIP3 1 0.51 5.58 4.96
73 INT181186 Binding of Rxra 78 0.35 14.93 4.87
74 INT204449 Gene_expression of T 17 0.32 9.77 4.77
75 INT4577 Negative_regulation of Thra 24 0.56 3.75 4.73
76 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
77 INT337882 Gene_expression of Nr2f2 1 0.76 3.45 4.6
78 INT54911 Localization of FOS 20 0.78 3.27 4.56
79 INT184269 Gene_expression of HMGB1 51 0.77 42.96 4.55
80 INT78719 Binding of Ucp1 8 0.41 8.93 4.5
81 INT54895 Binding of Epo 24 0.48 11.38 4.48
82 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
83 INT126608 Binding of Stat5a 7 0.48 0.46 4.38
84 INT154527 Gene_expression of POU5F1 180 0.78 34.01 4.34
85 INT134968 Localization of Ecm1 20 0.32 27.27 4.31
86 INT80626 Binding of KCNIP3 46 0.43 9.84 4.27
87 INT5219 Negative_regulation of DBP 43 0.57 23.35 4.26
88 INT9098 Positive_regulation of DBP 30 0.69 15.77 4.26
89 INT146355 Negative_regulation of Aes 15 0.51 7.83 4.25
90 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
91 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
92 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
93 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15
94 INT215085 Positive_regulation of Gene_expression of Hmgb1 17 0.63 16.81 4.13
95 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
96 INT91371 Negative_regulation of STAT3 34 0.59 25 4.08
97 INT97392 Gene_expression of Stat3 27 0.65 14.21 4.06
98 INT72936 Gene_expression of Pparg 39 0.77 19.01 4.02
99 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
100 INT63481 Gene_expression of FOSL1 11 0.75 1.39 4.01
101 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4
102 INT85190 Positive_regulation of FOSL1 5 0.67 4.21 3.97
103 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92
104 INT73750 Regulation of Gene_expression of YY1 7 0.44 0.28 3.91
105 INT176208 Gene_expression of Nr1h2 27 0.59 22.75 3.84
106 INT184288 Localization of HMGB1 20 0.61 14.5 3.84
107 INT123411 Gene_expression of Sp1 15 0.69 4.2 3.79
108 INT141658 Positive_regulation of Gene_expression of Sod2 51 0.69 35.6 3.71
109 INT92678 Positive_regulation of Ecm1 30 0.09 28.41 3.68
110 INT121818 Binding of STAT3 25 0.47 11.16 3.67
111 INT53891 Positive_regulation of Positive_regulation of YY1 5 0.49 0.24 3.65
112 INT84891 Gene_expression of PPARD 10 0.78 6.8 3.64
113 INT12598 Binding of DBP 20 0.48 13.11 3.62
114 INT240080 Negative_regulation of Transcription of KCNIP3 1 0.51 4.34 3.61
115 INT99453 Gene_expression of SOD2 25 0.77 13.28 3.6
116 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
117 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
118 INT78845 Binding of Pparg 16 0.44 11.67 3.53
119 INT132187 Gene_expression of Ecm1 14 0.21 8.12 3.52
120 INT192951 Negative_regulation of AES 15 0.38 6.38 3.5
121 INT29356 Positive_regulation of Binding of YY1 8 0.67 0.22 3.49
122 INT275878 Positive_regulation of Gene_expression of Aes 4 0.23 4.54 3.39
123 INT86071 Negative_regulation of Med15 3 0.43 1.19 3.38
124 INT171233 Binding of Ecm1 25 0.07 12.41 3.36
125 INT127111 Regulation of Inhba 5 0.60 2.85 3.28
126 INT75133 Positive_regulation of JUND 15 0.51 6.69 3.26
127 INT41559 Positive_regulation of Sp1 7 0.45 2.65 3.24
128 INT200443 Positive_regulation of AES 27 0.60 22.46 3.22
129 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
130 INT66191 Gene_expression of DBP 42 0.66 22.25 3.18
131 INT72618 Regulation of Tcf3 5 0.44 1.48 3.16
132 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
133 INT123409 Binding of Sp1 20 0.39 3.18 3.15
134 INT53065 Negative_regulation of Gene_expression of EPO 15 0.49 16.39 3.12
135 INT84890 Negative_regulation of PPARD 7 0.59 3.27 3.1
136 INT53889 Negative_regulation of Positive_regulation of YY1 6 0.41 0.57 3.05
137 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
138 INT2897 Positive_regulation of Thra 20 0.45 5.17 3.01
139 INT97393 Localization of Stat3 11 0.75 7.33 3.01
140 INT128179 Gene_expression of RHOA 7 0.64 2.48 3.01
141 INT163080 Gene_expression of STAT6 5 0.59 3.18 2.94
142 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
143 INT103607 Binding of Sp1 7 0.42 1.26 2.92
144 INT130080 Negative_regulation of Rxra 6 0.53 2.08 2.92
145 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
146 INT45503 Binding of EPO 42 0.48 24.85 2.88
147 INT53890 Transcription of YY1 8 0.67 1.53 2.88
148 INT15757 Gene_expression of JUND 11 0.75 2.47 2.86
149 INT241623 Gene_expression of Atf4 12 0.74 8.67 2.85
150 INT93213 Phosphorylation of Sp1 5 0.67 0.93 2.84
151 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
152 INT94327 Phosphorylation of Stat1 9 0.80 2.06 2.8
153 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
154 INT108358 Phosphorylation of FOS 12 0.80 6.33 2.79
155 INT8112 Regulation of EPO 38 0.58 22.04 2.76
156 INT15204 Negative_regulation of Sub1 5 0.32 0.43 2.75
157 INT321310 Positive_regulation of Nr1h4 1 0.49 1.75 2.75
158 INT1225 Regulation of Snai1 10 0.30 1.05 2.72
159 INT351263 Binding of CLOCK 1 0.18 0.46 2.71
160 INT119839 Gene_expression of STAT1 17 0.75 8.36 2.7
161 INT221269 Binding of BRCA1 14 0.40 31.77 2.7
162 INT60750 Gene_expression of HNF4A 12 0.65 8.29 2.68
163 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68
164 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
165 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56
166 INT23998 Positive_regulation of Sp1 4 0.40 0.51 2.56
167 INT59709 Negative_regulation of Negative_regulation of YY1 3 0.57 0.07 2.55
168 INT8111 Localization of EPO 32 0.81 19.53 2.54
169 INT89929 Positive_regulation of Positive_regulation of STAT3 22 0.65 9.21 2.54
170 INT126610 Phosphorylation of Stat5a 5 0.82 0.8 2.52
171 INT129917 Negative_regulation of Phosphorylation of Stat3 6 0.41 0.85 2.51
172 INT184272 Binding of HMGB1 14 0.37 8.78 2.49
173 INT66332 Gene_expression of Ucp1 40 0.75 40.09 2.48
174 INT127108 Gene_expression of Inhba 12 0.65 3.21 2.48
175 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
176 INT112974 Gene_expression of Ucp1 12 0.78 7.72 2.45
177 INT169073 Positive_regulation of Nr1h4 8 0.47 2.44 2.45
178 INT115474 Positive_regulation of Tlx2 5 0.70 4.03 2.44
179 INT103609 Transcription of Sp1 1 0.11 0.97 2.42
180 INT96876 Gene_expression of AHR 20 0.77 10.43 2.39
181 INT86147 Positive_regulation of Inhba 8 0.63 1.94 2.39
182 INT140993 Negative_regulation of Positive_regulation of Stat3 6 0.38 3.39 2.39
183 INT37057 Gene_expression of Tlx2 12 0.76 7.98 2.38
184 INT134964 Regulation of Ecm1 13 0.10 7.45 2.37
185 INT128174 Positive_regulation of Gene_expression of RHOA 7 0.36 1.5 2.36
186 INT160080 Localization of Ecm1 6 0.15 4.86 2.36
187 INT45597 Negative_regulation of Epo 22 0.59 12.47 2.35
188 INT48980 Positive_regulation of Transcription of FOS 10 0.67 3.07 2.34
189 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
190 INT163082 Negative_regulation of STAT6 2 0.42 2.35 2.28
191 INT52357 Gene_expression of Sub1 6 0.16 2.49 2.25
192 INT123705 Gene_expression of SMARCB1 40 0.73 19.47 2.2
193 INT115193 Positive_regulation of Phosphorylation of STAT3 30 0.64 11.37 2.2
194 INT81294 Negative_regulation of Positive_regulation of Pparg 7 0.58 4.39 2.2
195 INT101516 Positive_regulation of PPARD 8 0.49 4.75 2.19
196 INT78844 Regulation of Pparg 6 0.41 4 2.19
197 INT169072 Gene_expression of Nr1h4 7 0.60 6.23 2.18
198 INT96762 Gene_expression of RAI1 9 0.56 5.77 2.17
199 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
200 INT109334 Regulation of SOD2 13 0.60 7.48 2.14
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