GO:0006361

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Name transcription initiation from RNA polymerase I promoter
Categary Process
Go Slim No
Go Link GO:0006361
Unique Molecular Interactions 50
Total Molecular Interactions 59
Total Single Events 354
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for transcription initiation from RNA polymerase I promoter. They are ordered first by their pain relevance and then by number of times they were reported for transcription initiation from RNA polymerase I promoter. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34
2 INT164378 MAPK3 Positive_regulation of Transcription of PDYN 1 0.50 0.2 1.09
3 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
4 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
5 INT169296 PTPLA Positive_regulation of MAPK3 1 0.10 0.15 0.63
6 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
7 INT99486 OPRM1 Positive_regulation of MAPK3 1 0.22 0 0.55
8 INT106394 MAPK3 Positive_regulation of ADRBK1 1 0.48 0.06 0.53
9 INT131371 MAPK3 Positive_regulation of Il4 1 0.02 0.37 0.51
10 INT131367 MAPK3 Positive_regulation of Bcar3 1 0.00 0.37 0.51
11 INT131370 MAPK3 Positive_regulation of Gene_expression of Il4 1 0.02 0.37 0.51
12 INT102552 HGF Positive_regulation of MAPK3 1 0.38 0.47 0.47
13 INT106396 DYT10 Positive_regulation of MAPK3 1 0.50 0 0.42
14 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 0.11 0.39 0.42
15 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
16 INT162045 F2 Positive_regulation of Phosphorylation of MAPK3 1 0.30 0.99 0.3
17 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
18 INT134401 Negative_regulation of MAPK3 Negative_regulation of Gene_expression of ARMC3 1 0.19 1.16 0.13
19 INT134399 Negative_regulation of MAPK3 Positive_regulation of Phosphorylation of MAPK8 1 0.39 1.14 0.13
20 INT156829 EGF Positive_regulation of MAPK3 2 0.08 0.87 0.1
21 INT154164 Binding of Ttf1 and Cea 1 0.00 0.34 0.08
22 INT154168 Binding of KRT5 and Ttf1 1 0.02 0.34 0.08
23 INT146842 Tnf Regulation of Lipe 1 0.19 0.4 0.08
24 INT156839 Binding of CYP24A1 and MAPK3 1 0.31 0 0.07
25 INT156835 Binding of MAPK3 and TRPV6 1 0.21 0 0.07
26 INT319700 Ins1 Negative_regulation of Lipe 1 0.04 1.22 0.03
27 INT323572 Negative_regulation of Lipe Positive_regulation of Positive_regulation of Ly6 1 0.00 0.1 0
28 INT262731 Binding of CHN1 and TAF1A 1 0.00 0 0
29 INT243318 MAPK3 Negative_regulation of FOS 1 0.04 0.14 0
30 INT239080 Binding of PPY and KAT2B 1 0.02 2.38 0
31 INT93174 Ttf1 Positive_regulation of GNRH1 1 0.04 0.07 0
32 INT149429 ERCC2 Negative_regulation of Localization of IL8 1 0.05 0.38 0
33 INT342558 FGF9 Positive_regulation of MAPK3 1 0.03 1.21 0
34 INT93172 Ttf1 Negative_regulation of Transcription of Penk 1 0.01 0.07 0
35 INT227840 Binding of ERCC2 and ERCC6 1 0.11 0.66 0
36 INT242102 Nkx2-1 Regulation of Gene_expression of Ttf1 1 0.00 1.55 0
37 INT177917 Positive_regulation of EGF Positive_regulation of Phosphorylation of MAPK3 1 0.04 0.4 0
38 INT149431 ERCC2 Negative_regulation of Localization of Il6 1 0.14 0.2 0
39 INT227831 Binding of ERCC2 and PGBD3 1 0.07 0.23 0
40 INT254706 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0
41 INT254702 Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0
42 INT149432 ERCC2 Regulation of Localization of Il6 1 0.15 1.06 0
43 INT122545 FGF2 Positive_regulation of Positive_regulation of MAPK3 1 0.53 0 0
44 INT177912 EGF Regulation of MAPK3 1 0.02 0.84 0
45 INT149428 ERCC2 Regulation of Localization of IL8 1 0.05 0.53 0
46 INT93173 Ttf1 Positive_regulation of Erbb2 1 0.05 0.07 0
47 INT254705 Map2k2 Positive_regulation of Phosphorylation of MAPK3 1 0.08 0.86 0
48 INT73079 TTF1 Positive_regulation of GH1 1 0.04 0.33 0
49 INT342557 FGF2 Positive_regulation of MAPK3 1 0.03 1.21 0
50 INT177913 EGF Positive_regulation of Phosphorylation of MAPK3 1 0.04 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for transcription initiation from RNA polymerase I promoter. They are ordered first by their pain relevance and then by number of times they were reported in transcription initiation from RNA polymerase I promoter. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
2 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88
3 INT71785 Gene_expression of MAPK3 22 0.75 11.35 8.21
4 INT91618 Positive_regulation of Phosphorylation of MAPK3 21 0.67 7.99 7.65
5 INT94197 Negative_regulation of Phosphorylation of MAPK3 13 0.57 5.51 6.18
6 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
7 INT99487 Negative_regulation of MAPK3 15 0.57 7.13 5.39
8 INT71783 Positive_regulation of Gene_expression of MAPK3 9 0.59 4.59 3.05
9 INT87288 Positive_regulation of Positive_regulation of MAPK3 5 0.67 1.62 3.04
10 INT87284 Negative_regulation of Positive_regulation of MAPK3 7 0.41 2.65 2.38
11 INT118683 Regulation of Phosphorylation of MAPK3 3 0.44 2.92 1.82
12 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78
13 INT87282 Regulation of MAPK3 9 0.60 7.61 1.65
14 INT54996 Regulation of KAT2B 1 0.19 0.38 1.45
15 INT93168 Gene_expression of Ttf1 24 0.63 17.18 1.14
16 INT142950 Protein_catabolism of ERCC2 2 0.25 1.45 1.14
17 INT238919 Regulation of Gene_expression of MAPK3 3 0.16 1.6 1.13
18 INT164381 Regulation of Positive_regulation of MAPK3 2 0.60 1.49 1.03
19 INT339387 Gene_expression of Lipe 1 0.20 2.39 1
20 INT125627 Gene_expression of TTF1 11 0.78 12.68 0.78
21 INT35135 Positive_regulation of Lipe 2 0.45 1.25 0.58
22 INT166018 Protein_catabolism of MAPK3 1 0.23 0.59 0.56
23 INT134070 Binding of ERCC2 3 0.27 0.76 0.51
24 INT103901 Regulation of ERCC2 1 0.23 0.51 0.4
25 INT239084 Localization of KAT2B 4 0.73 3.08 0.36
26 INT125628 Negative_regulation of Gene_expression of TTF1 1 0.43 1.63 0.36
27 INT119081 Negative_regulation of Gene_expression of MAPK3 2 0.41 2 0.33
28 INT266973 Negative_regulation of KAT2B 1 0.01 0.99 0.29
29 INT339381 Positive_regulation of Gene_expression of Lipe 1 0.13 0.65 0.26
30 INT73080 Positive_regulation of TTF1 4 0.38 2.37 0.14
31 INT352511 Localization of Ttf1 1 0.01 1.03 0.12
32 INT261198 Phosphorylation of Lipe 1 0.07 0.92 0.1
33 INT70363 Negative_regulation of TTF1 1 0.03 0 0.1
34 INT101082 Positive_regulation of KAT2B 1 0.38 0.76 0.09
35 INT239085 Binding of KAT2B 1 0.18 2.04 0.09
36 INT93166 Positive_regulation of Ttf1 4 0.41 3.62 0.08
37 INT242098 Negative_regulation of Ttf1 2 0.04 2.52 0.07
38 INT132188 Positive_regulation of TAF1A 1 0.67 0.26 0.07
39 INT200136 Negative_regulation of ERCC2 1 0.37 1.91 0.07
40 INT339380 Regulation of Gene_expression of Lipe 1 0.11 0.26 0.06
41 INT93169 Binding of Ttf1 3 0.30 2.04 0.03
42 INT291906 Positive_regulation of Negative_regulation of ERCC2 1 0.40 0 0.03
43 INT93167 Transcription of Ttf1 2 0.56 0.22 0
44 INT93171 Positive_regulation of Gene_expression of Ttf1 1 0.57 0.32 0
45 INT269908 Regulation of Ttf1 1 0.10 0.14 0
46 INT323525 Regulation of Lipe 1 0.01 0.09 0
47 INT204253 Binding of TTF1 1 0.16 1.71 0
48 INT97787 Positive_regulation of Transcription of TTF1 1 0.16 0.15 0
49 INT149430 Localization of ERCC2 1 0.43 0.76 0
50 INT262745 Binding of TAF1A 1 0.01 0.05 0
51 INT323514 Negative_regulation of Lipe 1 0.02 0.1 0
52 INT97788 Transcription of TTF1 1 0.16 0.15 0
53 INT93170 Regulation of Gene_expression of Ttf1 1 0.50 0.09 0
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