GO:0006368

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Name transcription elongation from RNA polymerase II promoter
Categary Process
Go Slim No
Go Link GO:0006368
Unique Molecular Interactions 95
Total Molecular Interactions 117
Total Single Events 1316
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for transcription elongation from RNA polymerase II promoter. They are ordered first by their pain relevance and then by number of times they were reported for transcription elongation from RNA polymerase II promoter. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT227493 Binding of TCEA1 and SIRT2 1 0.01 1.55 1.93
2 INT178663 Binding of CXCR3 and TH1L 2 0.04 2.24 1.01
3 INT69307 Prkcq Negative_regulation of TH1L 1 0.00 0.98 0.98
4 INT209956 Binding of CD8A and RDBP 1 0.01 0.3 0.7
5 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69
6 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
7 INT333477 CXCL10 Positive_regulation of TH1L 1 0.14 0.32 0.56
8 INT73920 Binding of CCNT1 and CYP2B6 1 0.19 0.17 0.56
9 INT72525 Positive_regulation of TCEA1 Positive_regulation of Pomc 1 0.08 0 0.5
10 INT72524 Positive_regulation of TCEA1 Positive_regulation of Localization of Pomc 1 0.08 0 0.48
11 INT338086 PYCARD Positive_regulation of TCEA1 1 0.10 0 0.47
12 INT227495 Regulation of Binding of TCEA1 and SIRT2 1 0.01 0.45 0.45
13 INT178664 Binding of CCR5 and TH1L 1 0.04 1.04 0.44
14 INT352970 IL4 Negative_regulation of Positive_regulation of TH1L 1 0.01 0.91 0.4
15 INT305856 Polk Regulation of Gene_expression of TH1L 1 0.43 0.93 0.35
16 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33
17 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
18 INT176374 TH1L Positive_regulation of Gene_expression of TNF 1 0.31 0.46 0.31
19 INT226375 INCENP Positive_regulation of Regulation of TH1L 1 0.01 0.57 0.29
20 INT226376 INCENP Negative_regulation of Gene_expression of TH1L 1 0.00 0.61 0.29
21 INT176369 IL18 Regulation of TH1L 1 0.27 0.33 0.26
22 INT304582 IL12A Positive_regulation of Gene_expression of TH1L 1 0.21 0.83 0.25
23 INT304580 IL12A Regulation of Gene_expression of TH1L 1 0.19 0.82 0.25
24 INT186191 Binding of SCARB1 and TBP 1 0.03 2.57 0.24
25 INT325315 Binding of STAT3 and TH1L 1 0.16 0.6 0.23
26 INT174465 IL7 Positive_regulation of Gene_expression of TH1L 1 0.21 0.56 0.22
27 INT174469 Binding of IL4 and Positive_regulation of Gene_expression of TH1L 1 0.27 0.55 0.22
28 INT174466 Binding of IL7 and Positive_regulation of Gene_expression of TH1L 1 0.21 0.55 0.22
29 INT174462 IL7 Positive_regulation of TH1L 1 0.20 0.56 0.22
30 INT325317 Binding of IL12A and TH1L 1 0.18 0.59 0.22
31 INT331602 Binding of SSRP1 and Tlr4 1 0.03 0.9 0.21
32 INT226529 BTPs Negative_regulation of TH1L 1 0.05 0.22 0.2
33 INT226523 BTPs Negative_regulation of Gene_expression of TH1L 1 0.05 0.22 0.2
34 INT266046 Cstb Regulation of Gene_expression of Adrm1 1 0.00 0.7 0.18
35 INT337260 ELL Positive_regulation of Gene_expression of THBS1 1 0.11 0.82 0.18
36 INT337263 ELL Regulation of Gene_expression of THBS1 1 0.10 0.82 0.18
37 INT61976 TBP Negative_regulation of Tnf 1 0.24 1.17 0.17
38 INT132446 Binding of TF and COBRA1 1 0.01 0.63 0.17
39 INT226539 Nfatc3 Positive_regulation of Gene_expression of TH1L 1 0.11 0.19 0.17
40 INT132456 Binding of COBRA1 and Gtf3a 1 0.00 0.63 0.17
41 INT226334 TH1L Negative_regulation of Localization of IL4 1 0.07 0.18 0.16
42 INT226358 TH1L Negative_regulation of Localization of IL5 1 0.03 0.18 0.16
43 INT123194 Bmp6 Positive_regulation of TAF9 1 0.18 0.61 0.14
44 INT61965 TBP Negative_regulation of TNF 1 0.07 1.01 0.14
45 INT330467 IL12A Positive_regulation of Localization of TH1L 1 0.16 0.3 0.14
46 INT123193 Bmp6 Positive_regulation of Negative_regulation of TAF9 1 0.18 0.61 0.14
47 INT202813 Pin1 Positive_regulation of Regulation of TH1L 1 0.50 0 0.14
48 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
49 INT296027 TGFB1 Regulation of TH1L 1 0.02 1 0.13
50 INT227701 Tlx2 Positive_regulation of Regulation of SSRP1 1 0.00 0.69 0.12
51 INT296040 IL17A Regulation of TH1L 1 0.07 0.7 0.12
52 INT218784 Binding of TCEB2 and VHL 1 0.04 3.81 0.1
53 INT152034 Binding of HLA-A and RDBP 1 0.05 0.34 0.1
54 INT230465 Binding of TLR1 and TH1L 1 0.09 0.99 0.08
55 INT275896 IFN1@ Positive_regulation of Gene_expression of TH1L 1 0.09 0.37 0.08
56 INT230462 Binding of SNRNP70 and TH1L 1 0.00 0.99 0.08
57 INT186192 Binding of SCARB2 and TBP 1 0.02 0.58 0.05
58 INT320440 Binding of Adrm1 and Psmb10 1 0.00 0 0.04
59 INT265387 CXCL10 Positive_regulation of Positive_regulation of TH1L 1 0.06 0.24 0.04
60 INT285863 Positive_regulation of IL12A Regulation of TH1L 1 0.01 0.25 0.04
61 INT285864 IL12A Regulation of TH1L 1 0.00 0.25 0.04
62 INT314268 SUPT4H1 Positive_regulation of Gene_expression of PTGER2 1 0.01 0.13 0.03
63 INT314266 SUPT4H1 Positive_regulation of SPTLC1 1 0.02 0.13 0.03
64 INT211781 Binding of NTSR1 and RDBP 1 0.00 0.42 0
65 INT217779 POLR2B Regulation of Gene_expression of RASGRP1 1 0.01 0.2 0
66 INT225645 Binding of TAF1 and Acp5 1 0.01 0 0
67 INT217785 POLR2B Regulation of Gene_expression of MAP3K3 1 0.06 0.2 0
68 INT352859 IKBKAP Regulation of Regulation of MAPK8 1 0.10 0.28 0
69 INT197812 Binding of AMBP and RDBP 1 0.00 0.51 0
70 INT252900 PTTG1 Regulation of Gene_expression of TAF9 1 0.20 0.84 0
71 INT212082 Binding of NOVA2 and SSRP1 1 0.03 0.71 0
72 INT149429 ERCC2 Negative_regulation of Localization of IL8 1 0.05 0.38 0
73 INT227840 Binding of ERCC2 and ERCC6 1 0.11 0.66 0
74 INT351465 PRSS1 Regulation of Gene_expression of IKBKAP 1 0.00 0.65 0
75 INT253945 Adrm1 Negative_regulation of Hdl1 1 0.00 1.18 0
76 INT212085 Regulation of Binding of NOVA2 and SSRP1 1 0.03 0.71 0
77 INT149431 ERCC2 Negative_regulation of Localization of Il6 1 0.14 0.2 0
78 INT352857 Positive_regulation of TM4SF1 Positive_regulation of IKBKAP 1 0.45 0.27 0
79 INT227831 Binding of ERCC2 and PGBD3 1 0.07 0.23 0
80 INT352860 Positive_regulation of POLR2B Positive_regulation of Positive_regulation of IKBKAP 1 0.03 0.74 0
81 INT104862 NXT1 Positive_regulation of TH1L 1 0.03 0 0
82 INT104865 IL2 Positive_regulation of TH1L 1 0.38 0 0
83 INT252893 PTTG1 Positive_regulation of Gene_expression of TAF9 1 0.21 0.9 0
84 INT315889 Binding of B4GALNT1 and IKBKAP 1 0.00 0.68 0
85 INT212083 Binding of SSRP1 and NOXO1 1 0.02 0.67 0
86 INT178722 Binding of ARMCX2 and ADRM1 1 0.09 0.44 0
87 INT178724 Binding of HDHD1 and ADRM1 1 0.00 0.44 0
88 INT149432 ERCC2 Regulation of Localization of Il6 1 0.15 1.06 0
89 INT292149 Binding of GTF2B and SP1 1 0.03 0.4 0
90 INT149428 ERCC2 Regulation of Localization of IL8 1 0.05 0.53 0
91 INT104867 ZAK Positive_regulation of TH1L 1 0.33 0 0
92 INT292160 Binding of COBRA1 and TAR 1 0.00 0.73 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for transcription elongation from RNA polymerase II promoter. They are ordered first by their pain relevance and then by number of times they were reported in transcription elongation from RNA polymerase II promoter. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48642 Positive_regulation of TCEA1 92 0.70 24.59 53.64
2 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15
3 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02
4 INT102272 Regulation of TH1L 41 0.44 30.89 11.63
5 INT58904 Localization of TH1L 40 0.68 27.11 10.52
6 INT69306 Negative_regulation of TH1L 28 0.57 24.81 9.74
7 INT72523 Regulation of TCEA1 18 0.45 3.19 7.6
8 INT42132 Negative_regulation of TCEA1 13 0.51 4.12 6.28
9 INT132573 Negative_regulation of Gene_expression of TH1L 16 0.42 11.52 5.76
10 INT42133 Gene_expression of TCEA1 17 0.60 5.61 5.55
11 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
12 INT52203 Negative_regulation of Positive_regulation of TCEA1 5 0.51 3.27 4.48
13 INT48643 Regulation of Positive_regulation of TCEA1 6 0.53 1.94 3.83
14 INT252968 Positive_regulation of TAF9 11 0.45 5.28 3.68
15 INT181249 Binding of TCEA1 8 0.32 2.12 3.66
16 INT212563 Gene_expression of Adrm1 26 0.13 11.46 3.58
17 INT176386 Positive_regulation of Gene_expression of TH1L 14 0.32 9.17 3.4
18 INT252999 Gene_expression of TAF9 12 0.75 12.65 2.92
19 INT181250 Localization of TCEA1 6 0.75 1.54 2.61
20 INT75813 Positive_regulation of Positive_regulation of TCEA1 1 0.50 1.28 2.49
21 INT221762 Regulation of Gene_expression of Adrm1 4 0.07 4.45 2.42
22 INT9119 Negative_regulation of TAF9 4 0.42 5.21 2.16
23 INT262317 Binding of TAF9 7 0.31 9.67 2.15
24 INT248374 Binding of IKBKAP 10 0.42 10.45 1.9
25 INT221791 Transcription of TH1L 4 0.45 3.98 1.84
26 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78
27 INT183276 Negative_regulation of Adrm1 10 0.04 7.25 1.74
28 INT95134 Binding of TH1L 6 0.47 3.67 1.68
29 INT209962 Binding of RDBP 4 0.11 2.93 1.27
30 INT206696 Regulation of Gene_expression of TH1L 5 0.20 4.44 1.26
31 INT192807 Gene_expression of SSRP1 14 0.49 19.28 1.15
32 INT142950 Protein_catabolism of ERCC2 2 0.25 1.45 1.14
33 INT67590 Gene_expression of RDBP 9 0.51 5.17 1.1
34 INT221795 Negative_regulation of Localization of TH1L 2 0.31 2.17 1.07
35 INT38625 Gene_expression of ELL 8 0.58 12.53 1
36 INT114830 Positive_regulation of Regulation of TCEA1 2 0.41 0.11 0.94
37 INT8159 Binding of ELL 7 0.36 12.62 0.84
38 INT85652 Positive_regulation of RDBP 4 0.38 1.76 0.83
39 INT61971 Gene_expression of TBP 9 0.65 5.14 0.8
40 INT116763 Gene_expression of IKBKAP 63 0.78 54.53 0.79
41 INT51757 Gene_expression of COBRA1 4 0.51 2.71 0.75
42 INT209963 Positive_regulation of Binding of RDBP 1 0.07 0.3 0.71
43 INT78183 Negative_regulation of Adrm1 8 0.09 3.4 0.65
44 INT351509 Positive_regulation of IKBKAP 19 0.70 29.01 0.63
45 INT212562 Positive_regulation of Adrm1 16 0.10 5.08 0.62
46 INT143398 Regulation of ELL 2 0.44 2.17 0.59
47 INT37351 Negative_regulation of IKBKAP 16 0.58 9.6 0.56
48 INT323004 Transcription of TAF9 1 0.05 0.79 0.54
49 INT61972 Negative_regulation of TBP 5 0.32 3.56 0.53
50 INT134070 Binding of ERCC2 3 0.27 0.76 0.51
51 INT187377 Negative_regulation of Regulation of TH1L 1 0.09 0.89 0.51
52 INT105210 Positive_regulation of Adrm1 7 0.06 4.09 0.5
53 INT264100 Gene_expression of CCNT1 2 0.34 2.45 0.49
54 INT226467 Phosphorylation of TH1L 3 0.30 1.6 0.48
55 INT130141 Phosphorylation of POLR2B 1 0.29 0.57 0.47
56 INT299800 Negative_regulation of Positive_regulation of TH1L 2 0.20 1.05 0.44
57 INT250468 Positive_regulation of Gene_expression of Adrm1 2 0.04 2.26 0.44
58 INT329447 Regulation of Positive_regulation of TH1L 1 0.22 0.88 0.44
59 INT189176 Positive_regulation of Localization of TH1L 5 0.23 2.93 0.42
60 INT212088 Positive_regulation of Gene_expression of SSRP1 3 0.37 3.53 0.41
61 INT61975 Positive_regulation of TBP 5 0.28 4.01 0.4
62 INT103901 Regulation of ERCC2 1 0.23 0.51 0.4
63 INT226448 Positive_regulation of Transcription of TH1L 1 0.18 0.67 0.4
64 INT322997 Localization of TAF9 1 0.05 1.2 0.4
65 INT283994 Positive_regulation of Positive_regulation of TH1L 1 0.22 0.62 0.38
66 INT192806 Binding of SSRP1 11 0.27 9.12 0.37
67 INT212565 Regulation of Adrm1 3 0.04 2.41 0.36
68 INT292654 Positive_regulation of Binding of TH1L 1 0.22 0.36 0.36
69 INT230827 Regulation of COBRA1 1 0.02 1.08 0.35
70 INT212564 Negative_regulation of Gene_expression of Adrm1 3 0.05 1.7 0.34
71 INT192809 Negative_regulation of SSRP1 2 0.04 4.06 0.33
72 INT252969 Positive_regulation of Gene_expression of TAF9 5 0.67 5.22 0.32
73 INT226457 Positive_regulation of Phosphorylation of TH1L 1 0.16 0.98 0.29
74 INT95606 Positive_regulation of ADRM1 6 0.40 1.99 0.28
75 INT203010 Gene_expression of ADRM1 3 0.12 0.6 0.28
76 INT275900 Regulation of Localization of TH1L 2 0.26 0.99 0.26
77 INT227698 Regulation of SSRP1 4 0.03 2.88 0.24
78 INT151851 Positive_regulation of Regulation of TH1L 3 0.40 0.97 0.23
79 INT239796 Binding of TAF1 1 0.01 0.33 0.23
80 INT116762 Positive_regulation of Gene_expression of IKBKAP 10 0.70 9.79 0.19
81 INT250467 Localization of Adrm1 2 0.06 0.97 0.19
82 INT250469 Positive_regulation of Localization of Adrm1 2 0.04 0.97 0.19
83 INT351511 Transcription of IKBKAP 30 0.71 15.51 0.18
84 INT186140 Gene_expression of Adrm1 2 0.06 1.01 0.18
85 INT61973 Positive_regulation of Gene_expression of TBP 2 0.49 1.5 0.18
86 INT61974 Positive_regulation of Negative_regulation of TBP 1 0.28 1.2 0.18
87 INT301343 Negative_regulation of Positive_regulation of ELL 1 0.08 1.64 0.17
88 INT238096 Positive_regulation of ELL 4 0.09 2.68 0.16
89 INT147095 Regulation of Binding of TH1L 1 0.44 0.38 0.16
90 INT285875 Positive_regulation of Negative_regulation of TH1L 1 0.09 0.74 0.15
91 INT292259 Regulation of Gene_expression of CCNT1 1 0.27 1.27 0.15
92 INT351522 Localization of IKBKAP 1 0.80 5.05 0.13
93 INT114901 Binding of TBP 6 0.17 2.45 0.11
94 INT292237 Negative_regulation of Gene_expression of CCNT1 1 0.19 0.58 0.11
95 INT351503 Positive_regulation of Negative_regulation of IKBKAP 1 0.50 1.49 0.11
96 INT324246 Regulation of GTF2B 1 0.02 0.2 0.1
97 INT218786 Transcription of TCEB2 1 0.07 3.73 0.1
98 INT212172 Binding of Adrm1 7 0.36 1.38 0.09
99 INT212090 Regulation of Gene_expression of SSRP1 2 0.33 1.02 0.09
100 INT187558 Transcription of RDBP 1 0.03 0.32 0.09
101 INT252991 Regulation of TAF9 2 0.44 3.54 0.08
102 INT25998 Positive_regulation of SSRP1 5 0.43 2.47 0.07
103 INT203012 Regulation of ADRM1 5 0.11 1.79 0.07
104 INT355119 Transcription of SSRP1 1 0.50 0.62 0.07
105 INT344841 Localization of SSRP1 1 0.04 0.9 0.07
106 INT200136 Negative_regulation of ERCC2 1 0.37 1.91 0.07
107 INT351520 Negative_regulation of Gene_expression of IKBKAP 9 0.59 6.4 0.06
108 INT314272 Gene_expression of SUPT4H1 1 0.14 0.18 0.06
109 INT215445 Transcription of Adrm1 2 0.08 0.08 0.05
110 INT93917 Transcription of TCEA1 1 0.13 0 0.05
111 INT351502 Positive_regulation of Transcription of IKBKAP 1 0.50 2.86 0.05
112 INT212930 Localization of ELL 2 0.15 0.87 0.04
113 INT309258 Localization of TBP 2 0.27 1.78 0.03
114 INT175888 Gene_expression of POLR2B 2 0.04 0.32 0.03
115 INT268681 Binding of GTF2B 1 0.21 1.16 0.03
116 INT291906 Positive_regulation of Negative_regulation of ERCC2 1 0.40 0 0.03
117 INT351501 Regulation of IKBKAP 18 0.62 12.5 0
118 INT351500 Regulation of Transcription of IKBKAP 6 0.45 2.72 0
119 INT351491 Regulation of Gene_expression of IKBKAP 5 0.62 5.34 0
120 INT230372 Negative_regulation of ELL 5 0.03 1.35 0
121 INT287187 Regulation of TBP 3 0.13 2.42 0
122 INT298408 Transcription of POLR2B 3 0.12 2.78 0
123 INT175893 Regulation of POLR2B 2 0.08 1.34 0
124 INT292243 Positive_regulation of Gene_expression of CCNT1 1 0.21 0.29 0
125 INT93632 Negative_regulation of Gene_expression of TCEA1 1 0.14 0.09 0
126 INT211829 Protein_catabolism of TBP 1 0.17 0.09 0
127 INT175901 Negative_regulation of POLR2B 1 0.00 0.34 0
128 INT298404 Regulation of Transcription of POLR2B 1 0.05 1.02 0
129 INT351510 Regulation of Regulation of IKBKAP 1 0.27 0.45 0
130 INT352870 Positive_regulation of Positive_regulation of IKBKAP 1 0.70 1.54 0
131 INT236889 Transcription of ADRM1 1 0.11 0.8 0
132 INT352882 Negative_regulation of Regulation of IKBKAP 1 0.43 0.67 0
133 INT351497 Regulation of Negative_regulation of IKBKAP 1 0.27 0.57 0
134 INT292838 Gene_expression of TAF1 1 0.04 0.48 0
135 INT322322 Transcription of TBP 1 0.22 0.61 0
136 INT351504 Negative_regulation of Transcription of IKBKAP 1 0.42 1.12 0
137 INT351524 Protein_catabolism of IKBKAP 1 0.76 0.54 0
138 INT203011 Localization of ADRM1 1 0.13 0 0
139 INT261709 Protein_catabolism of ADRM1 1 0.13 0.5 0
140 INT344249 Binding of ADRM1 1 0.02 0 0
141 INT267790 Binding of Adrm1 1 0.07 0 0
142 INT292235 Negative_regulation of CCNT1 1 0.19 0.16 0
143 INT292221 Binding of CCNT1 1 0.16 0.73 0
144 INT352861 Positive_regulation of Transcription of POLR2B 1 0.04 0.73 0
145 INT351515 Positive_regulation of Localization of IKBKAP 1 0.43 1.22 0
146 INT292240 Positive_regulation of CCNT1 1 0.21 0.52 0
147 INT346607 Positive_regulation of Positive_regulation of RDBP 1 0.22 0.13 0
148 INT261710 Phosphorylation of ADRM1 1 0.08 0.44 0
149 INT317587 Negative_regulation of Negative_regulation of Adrm1 1 0.03 0 0
150 INT346970 Binding of POLR2B 1 0.03 0.36 0
151 INT314271 Binding of SUPT4H1 1 0.08 0 0
152 INT352872 Positive_regulation of POLR2B 1 0.05 0.72 0
153 INT149430 Localization of ERCC2 1 0.43 0.76 0
154 INT192803 Negative_regulation of Gene_expression of SSRP1 1 0.05 2.36 0
155 INT256935 Regulation of CCNT1 1 0.01 0.43 0
156 INT351488 Regulation of Binding of IKBKAP 1 0.45 1.06 0
157 INT317588 Regulation of Adrm1 1 0.05 0 0
158 INT212091 Negative_regulation of Binding of SSRP1 1 0.12 0.57 0
159 INT252984 Regulation of Gene_expression of TAF9 1 0.26 0.99 0
160 INT239636 Negative_regulation of RDBP 1 0.24 0 0
161 INT351490 Positive_regulation of Binding of IKBKAP 1 0.50 0.55 0
162 INT351498 Negative_regulation of Binding of IKBKAP 1 0.37 0.51 0
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