GO:0006417

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Name regulation of translation
Categary Process
Go Slim No
Go Link GO:0006417
Unique Molecular Interactions 981
Total Molecular Interactions 1354
Total Single Events 9699
Pain Genes Associated 53

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of translation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of translation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
3 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
4 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
5 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
6 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
7 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
8 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
9 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
10 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
11 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
12 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
13 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
14 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
15 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44
16 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
17 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
18 INT341218 Binding of Eif4e and Eif4ebp1 1 0.19 2.65 1.23
19 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
20 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
21 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
22 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
23 INT108546 BCL2L10 Regulation of MAPKAPK5 1 0.03 1.22 1.1
24 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
25 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08
26 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
27 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
28 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
29 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
30 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
31 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
32 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
33 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
34 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
35 INT159993 App Regulation of Gene_expression of Bace1 1 0.46 0.32 0.92
36 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
37 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91
38 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
39 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
40 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
41 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
42 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
43 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
44 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
45 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
46 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
47 INT150680 Pomc Negative_regulation of Gene_expression of Eif2ak3 1 0.35 0.07 0.8
48 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 0.01 1.2 0.79
49 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79
50 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
51 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
52 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
53 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
54 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
55 INT126304 Binding of Rgs2 and Pag1 1 0.16 0.41 0.72
56 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7
57 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
58 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
59 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
60 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
61 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
62 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
63 INT169293 PTPLA Positive_regulation of AKT1 1 0.10 0.15 0.64
64 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
65 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
66 INT2700 Binding of App and Cpe 1 0.00 0 0.63
67 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
68 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
69 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
70 INT84771 Positive_regulation of Binding of App and Pag1 1 0.17 0.9 0.62
71 INT278695 MTX1 Negative_regulation of Phosphorylation of AKT1 1 0.04 0.81 0.62
72 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
73 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
74 INT166387 Binding of Gnb2l1 and Mdk 1 0.30 0.24 0.61
75 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
76 INT166385 Binding of Araf and Gnb2l1 1 0.23 0.24 0.6
77 INT120203 Binding of App and Il1 1 0.17 1.28 0.59
78 INT120204 Binding of App and Il1f5 1 0.09 1.28 0.59
79 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
80 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
81 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
82 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
83 INT84770 Binding of App and Pag1 1 0.13 0.89 0.57
84 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
85 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
86 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
87 INT167618 Rho Regulation of App 1 0.17 0.88 0.55
88 INT150291 Grk1 Positive_regulation of Gene_expression of Igf1 1 0.16 0.98 0.55
89 INT201944 CXCL10 Positive_regulation of Phosphorylation of AKT1 1 0.09 0.79 0.55
90 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
91 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55
92 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
93 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
94 INT350150 Binding of LPP and ATXN2 1 0.35 1.82 0.54
95 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
96 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
97 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
98 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54
99 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
100 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
101 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
102 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
103 INT97952 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1 1 0.03 0.72 0.51
104 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
105 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5
106 INT97951 ST3GAL3 Positive_regulation of AKT1 1 0.04 0.7 0.5
107 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49
108 INT150205 Tnrc6a Negative_regulation of PTGS2 1 0.00 0.42 0.49
109 INT108568 Calca Positive_regulation of Igf1 1 0.51 0.08 0.48
110 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
111 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
112 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
113 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
114 INT162932 TXNRD1 Negative_regulation of Phosphorylation of AKT1 1 0.14 1.01 0.47
115 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
116 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
117 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
118 INT183322 Binding of CNNM4 and RBM4B 1 0.12 0.59 0.46
119 INT162929 NQO1 Negative_regulation of Phosphorylation of AKT1 1 0.41 1 0.46
120 INT244050 Binding of Gnb2l1 and Prkca 1 0.01 0 0.45
121 INT167621 Psenen Positive_regulation of App 1 0.02 0.86 0.44
122 INT167617 Bace2 Positive_regulation of App 1 0.06 0.87 0.44
123 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 0.00 0.88 0.44
124 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44
125 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
126 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42
127 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
128 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
129 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
130 INT322396 Hist1h1t Positive_regulation of Akt1 1 0.01 0 0.42
131 INT160048 INPPL1 Regulation of Gene_expression of AKT1 1 0.28 0.6 0.42
132 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
133 INT121851 AKT1 Regulation of ROS1 1 0.16 0.52 0.41
134 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
135 INT121848 AKT1 Regulation of CASP8 1 0.18 0.52 0.41
136 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
137 INT121854 AKT1 Regulation of BID 1 0.17 0.52 0.41
138 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
139 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
140 INT108197 AKT1 Regulation of JUN 1 0.29 0.25 0.4
141 INT231842 Pcdh8 Positive_regulation of Akt1 1 0.00 1.59 0.4
142 INT79577 APP Negative_regulation of PENK 1 0.12 0.35 0.4
143 INT78121 Positive_regulation of Binding of App and 20S 1 0.23 0.61 0.4
144 INT78122 Binding of App and 20S 1 0.16 0.61 0.4
145 INT302824 Mapkapk5 Positive_regulation of Phosphorylation of Hspb2 1 0.11 0.64 0.4
146 INT121853 Gene_expression of ROS1 Negative_regulation of AKT1 1 0.25 0.49 0.4
147 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4
148 INT99304 Igf1 Positive_regulation of Gh1 1 0.44 0.39 0.39
149 INT166155 Ccr9 Positive_regulation of Akt1 1 0.58 2.14 0.39
150 INT134167 Binding of ADRA2A and APLP1 1 0.09 0.64 0.39
151 INT323967 Il6 Positive_regulation of Gene_expression of App 1 0.10 0.86 0.38
152 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37
153 INT78854 APP Positive_regulation of Localization of IL6 1 0.14 0.79 0.37
154 INT353392 Binding of DRD4 and NCK1 1 0.37 0.62 0.37
155 INT134168 Binding of ADRA2B and APLP1 1 0.06 0.7 0.37
156 INT89386 INS Positive_regulation of Phosphorylation of AKT1 3 0.43 1.48 0.36
157 INT299288 AKT1 Positive_regulation of RPTOR 1 0.34 0.05 0.36
158 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36
159 INT272953 Negative_regulation of Binding of TNF and Igf1 1 0.16 1.48 0.36
160 INT63278 Gpm6a Regulation of Igf1 1 0.01 0 0.36
161 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
162 INT272952 Igf1 Positive_regulation of Localization of TNF 1 0.19 1.53 0.35
163 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
164 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
165 INT176135 AKT1 Regulation of Localization of CYCS 1 0.43 2.16 0.35
166 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
167 INT309118 Dlat Positive_regulation of Positive_regulation of Akt1 1 0.03 0.32 0.34
168 INT277656 Igf1 Positive_regulation of Igfbp3 1 0.01 0.4 0.34
169 INT249019 Gabrg1 Positive_regulation of Akt1 1 0.02 0 0.34
170 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
171 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33
172 INT124376 Prodh2 Positive_regulation of App 1 0.00 0.66 0.33
173 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33
174 INT302830 Mapk14 Regulation of Mapkapk5 1 0.12 0.53 0.33
175 INT124379 Prodh2 Positive_regulation of Localization of App 1 0.00 0.66 0.33
176 INT341215 Binding of Eif4e and Eif4g3 1 0.10 0.41 0.33
177 INT337412 AKT3 Negative_regulation of Localization of AKT2 1 0.09 0.5 0.32
178 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32
179 INT337418 AKT2 Negative_regulation of Localization of AKT3 1 0.09 0.5 0.32
180 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
181 INT337410 AKT3 Negative_regulation of AKT1 1 0.09 0.49 0.32
182 INT337414 AKT2 Negative_regulation of AKT1 1 0.10 0.5 0.32
183 INT147434 Psenen Positive_regulation of APP 1 0.01 0.58 0.32
184 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
185 INT303063 Akt1 Negative_regulation of Gene_expression of Syn1 1 0.09 0.45 0.31
186 INT341214 Tas2r130 Positive_regulation of Phosphorylation of Eif4ebp1 1 0.00 0.68 0.31
187 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
188 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
189 INT65268 Igf1 Positive_regulation of Col7a1 1 0.48 0 0.3
190 INT299307 AKT1 Positive_regulation of Positive_regulation of AKT1S1 1 0.10 0 0.3
191 INT68977 App Positive_regulation of Localization of Mmp9 1 0.05 0.38 0.3
192 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
193 INT304497 Mknk1 Positive_regulation of Nos1 1 0.19 0.53 0.3
194 INT299289 AKT1 Positive_regulation of Positive_regulation of TSC2 1 0.17 0 0.3
195 INT140385 Spp1 Negative_regulation of FOXO3 1 0.04 1.29 0.3
196 INT304536 Mknk1 Positive_regulation of PRKG1 1 0.03 0.53 0.3
197 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 0.37 3.89 0.29
198 INT319220 FSIP1 Regulation of APP 1 0.29 1.46 0.29
199 INT323653 Binding of Igf1 and Igfbp1 1 0.20 1.14 0.29
200 INT291202 Positive_regulation of INS Positive_regulation of AKT1 1 0.01 0.76 0.29

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of translation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of translation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65500 Gene_expression of App 605 0.78 429.94 98.31
2 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
3 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
4 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
5 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
6 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
7 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
8 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
9 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
10 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
11 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
12 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
13 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
14 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
15 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
16 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
17 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
18 INT11625 Localization of App 98 0.78 55.46 20.86
19 INT16794 Binding of App 103 0.48 64.87 19.79
20 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
21 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
22 INT65502 Regulation of App 77 0.62 52.05 19.44
23 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
24 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
25 INT109031 Positive_regulation of Eif2ak3 44 0.69 21.11 14.72
26 INT54052 Gene_expression of App 33 0.78 25.08 14.7
27 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
28 INT109034 Gene_expression of Eif2ak3 37 0.77 17.11 14.19
29 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
30 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
31 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
32 INT29745 Binding of APP 47 0.48 26.49 12.4
33 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38
34 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
35 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48
36 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15
37 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
38 INT159116 Gene_expression of Gnb2l1 12 0.77 2.79 9.49
39 INT41569 Regulation of APP 32 0.62 17.15 9.4
40 INT150678 Positive_regulation of Gene_expression of Eif2ak3 17 0.69 6.64 8.99
41 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
42 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
43 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98
44 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
45 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
46 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
47 INT56031 Positive_regulation of App 25 0.69 13.46 7.37
48 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
49 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
50 INT166383 Positive_regulation of Gene_expression of Gnb2l1 1 0.69 2.19 7.02
51 INT228659 Phosphorylation of Eif4ebp1 10 0.80 27.53 6.87
52 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
53 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
54 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26
55 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1
56 INT9321 Transcription of Igf1 25 0.69 10.2 6.08
57 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
58 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
59 INT8916 Regulation of Igf1 45 0.60 13.06 5.81
60 INT151032 Localization of Igf1 49 0.76 26.32 5.71
61 INT159115 Negative_regulation of Gene_expression of Gnb2l1 3 0.42 1.33 5.59
62 INT107173 Phosphorylation of App 20 0.82 12.64 5.3
63 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
64 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
65 INT105336 Regulation of AKT1 52 0.56 32.53 4.89
66 INT131692 Negative_regulation of Localization of App 9 0.53 4.69 4.82
67 INT137336 Phosphorylation of Eif2ak3 14 0.79 4.72 4.78
68 INT134657 Localization of Akt1 37 0.68 11.58 4.62
69 INT159122 Positive_regulation of Gnb2l1 8 0.69 2.2 4.61
70 INT78116 Positive_regulation of Gene_expression of App 12 0.70 10.78 4.52
71 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
72 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
73 INT49360 Localization of Igf1 22 0.76 6.96 4.26
74 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21
75 INT58003 Localization of APP 32 0.80 13.75 4.2
76 INT75136 Binding of Akt1 27 0.27 8.81 4.15
77 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07
78 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
79 INT99821 Negative_regulation of Gene_expression of APP 20 0.42 15.21 3.94
80 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77
81 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
82 INT136692 Localization of Akt1 12 0.78 2.14 3.65
83 INT11627 Positive_regulation of Localization of App 14 0.62 6.27 3.64
84 INT99819 Negative_regulation of Positive_regulation of APP 6 0.58 4.41 3.64
85 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
86 INT70089 Negative_regulation of Binding of APP 7 0.59 6.45 3.44
87 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
88 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23
89 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19
90 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
91 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02
92 INT200670 Gene_expression of AKT2 25 0.75 16.25 3
93 INT108773 Negative_regulation of Binding of App 10 0.42 7.26 2.96
94 INT120201 Gene_expression of Aco1 54 0.35 26.29 2.95
95 INT54055 Regulation of Gene_expression of App 7 0.62 4.04 2.93
96 INT93777 Negative_regulation of Rgs2 3 0.43 2.5 2.81
97 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8
98 INT178772 Transcription of App 17 0.70 10.79 2.79
99 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
100 INT147429 Negative_regulation of Positive_regulation of App 8 0.40 8.73 2.78
101 INT54054 Binding of App 4 0.48 10.89 2.78
102 INT166381 Negative_regulation of Gnb2l1 1 0.43 0.73 2.68
103 INT214355 Binding of Akt1 13 0.36 3.72 2.59
104 INT203819 Binding of Eif2ak3 9 0.37 5.94 2.57
105 INT139735 Positive_regulation of Transcription of Igf1 4 0.53 1.93 2.49
106 INT66544 Binding of Igf1 23 0.46 8.33 2.44
107 INT202341 Gene_expression of Mapkapk5 3 0.46 3.67 2.43
108 INT162513 Regulation of Protein_catabolism of APP 5 0.51 1.79 2.36
109 INT159117 Regulation of Gene_expression of Gnb2l1 3 0.56 0.5 2.36
110 INT11626 Regulation of Localization of App 4 0.45 1.51 2.34
111 INT56030 Regulation of App 8 0.62 4.06 2.32
112 INT118791 Binding of AKT1 32 0.48 15.51 2.25
113 INT138286 Regulation of Positive_regulation of Akt1 13 0.45 4.93 2.22
114 INT110038 Negative_regulation of Aco1 26 0.23 17.41 2.2
115 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14
116 INT124772 Regulation of Binding of App 6 0.45 4.92 2.09
117 INT39008 Localization of App 13 0.77 9.07 2.05
118 INT281878 Positive_regulation of Gene_expression of Aco1 35 0.31 17.15 1.98
119 INT156666 Positive_regulation of Localization of Igf1 11 0.62 6.94 1.95
120 INT142341 Positive_regulation of Transcription of Igf1 8 0.49 2.44 1.95
121 INT150675 Regulation of Gene_expression of Eif2ak3 3 0.40 1.11 1.93
122 INT142774 Regulation of Phosphorylation of App 1 0.59 2.27 1.93
123 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
124 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83
125 INT139402 Negative_regulation of Tnrc6a 1 0.00 2.22 1.8
126 INT159120 Protein_catabolism of Gnb2l1 1 0.26 0.37 1.79
127 INT121117 Regulation of Protein_catabolism of App 10 0.62 6.41 1.78
128 INT107915 Regulation of Negative_regulation of App 6 0.45 4.47 1.76
129 INT142236 Regulation of Phosphorylation of Akt1 13 0.61 5.02 1.75
130 INT44888 Phosphorylation of EIF2S1 12 0.80 5.7 1.7
131 INT165332 Negative_regulation of Negative_regulation of Akt1 5 0.42 3.27 1.7
132 INT117714 Regulation of Positive_regulation of Akt1 3 0.61 0.44 1.61
133 INT136788 Regulation of Eif4e 3 0.61 0 1.61
134 INT109033 Positive_regulation of Positive_regulation of Eif2ak3 2 0.45 2.36 1.59
135 INT302790 Positive_regulation of Mapkapk5 1 0.25 2.6 1.55
136 INT133863 Positive_regulation of Protein_catabolism of App 12 0.59 7.53 1.52
137 INT58004 Positive_regulation of Localization of APP 5 0.46 2.1 1.5
138 INT49361 Regulation of Positive_regulation of Igf1 2 0.45 2.15 1.49
139 INT150677 Negative_regulation of Eif2ak3 9 0.58 6.24 1.46
140 INT113514 Positive_regulation of Eif2s1 2 0.49 0.85 1.46
141 INT25943 Transcription of App 5 0.53 1.79 1.44
142 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41
143 INT125796 Regulation of Gene_expression of APP 8 0.59 5.95 1.41
144 INT129700 Regulation of Positive_regulation of App 3 0.43 1.86 1.41
145 INT90491 Binding of Igf1 25 0.44 9.75 1.36
146 INT215864 Localization of Eif2ak3 5 0.75 3.26 1.36
147 INT214073 Binding of TSC1 9 0.37 22 1.34
148 INT141529 Regulation of Positive_regulation of APP 3 0.44 0.31 1.34
149 INT103488 Positive_regulation of Localization of App 5 0.50 3.05 1.28
150 INT167409 Regulation of Gene_expression of AKT1 8 0.56 4.86 1.23
151 INT160054 Localization of AKT2 4 0.73 1.93 1.18
152 INT135556 Localization of AKT1 38 0.69 12.78 1.17
153 INT228661 Negative_regulation of Phosphorylation of Eif4ebp1 6 0.41 2.25 1.16
154 INT142616 Negative_regulation of Positive_regulation of Igf1 5 0.43 1.56 1.16
155 INT100137 Positive_regulation of Negative_regulation of App 2 0.41 1.26 1.16
156 INT136783 Regulation of Regulation of Eif4e 1 0.45 0 1.16
157 INT118792 Regulation of Positive_regulation of AKT1 8 0.61 3.73 1.15
158 INT115982 Positive_regulation of KRT7 18 0.50 19.81 1.14
159 INT135899 Regulation of Binding of APP 3 0.45 1.22 1.14
160 INT176147 Regulation of Phosphorylation of AKT1 14 0.41 6.41 1.13
161 INT207203 Transcription of Akt1 6 0.67 3.73 1.1
162 INT136785 Phosphorylation of Eif4e 2 0.82 0 1.1
163 INT108551 Gene_expression of MAPKAPK5 1 0.15 1.23 1.1
164 INT108553 Negative_regulation of Gene_expression of MAPKAPK5 1 0.09 1.23 1.1
165 INT155563 Positive_regulation of Mknk1 2 0.54 2.12 1.08
166 INT108552 Regulation of MAPKAPK5 1 0.10 1.19 1.08
167 INT137338 Regulation of Eif2ak3 8 0.45 5.5 1.07
168 INT39009 Negative_regulation of App 6 0.38 3.37 1.07
169 INT202218 Positive_regulation of Aco1 4 0.27 12.31 1.06
170 INT191050 Positive_regulation of Negative_regulation of Akt1 6 0.31 1.82 1.03
171 INT350157 Binding of ATXN2 1 0.33 3.53 1.02
172 INT73465 Transcription of TSC1 4 0.07 3.47 0.96
173 INT126102 Binding of Tnrc6a 1 0.00 1.03 0.96
174 INT281594 Phosphorylation of Foxo3 3 0.67 21.16 0.95
175 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94
176 INT163508 Regulation of Gene_expression of Akt1 3 0.45 1.65 0.92
177 INT341195 Binding of Eif4e 1 0.38 3.87 0.92
178 INT84571 Gene_expression of Rgs2 6 0.67 3.18 0.89
179 INT160056 Positive_regulation of AKT2 3 0.48 1.43 0.88
180 INT240368 Positive_regulation of Localization of Eif2ak3 1 0.34 0.66 0.87
181 INT271605 Regulation of Gene_expression of AKT2 1 0.44 0.81 0.87
182 INT167607 Positive_regulation of Binding of App 8 0.50 2.97 0.86
183 INT341181 Positive_regulation of Phosphorylation of Eif4ebp1 1 0.30 4.99 0.86
184 INT162514 Positive_regulation of Regulation of APP 1 0.41 0.37 0.86
185 INT109032 Negative_regulation of Positive_regulation of Eif2ak3 1 0.38 0.94 0.85
186 INT99375 Positive_regulation of Binding of APP 3 0.61 1.63 0.83
187 INT107161 Positive_regulation of MAPKAPK5 2 0.16 1.15 0.82
188 INT302768 Regulation of Mapkapk5 1 0.24 1.6 0.82
189 INT224958 Negative_regulation of Transcription of Igf1 5 0.56 1.37 0.81
190 INT302792 Transcription of Mapkapk5 1 0.38 1.37 0.8
191 INT74019 Regulation of TSC1 27 0.35 23.61 0.79
192 INT154053 Negative_regulation of Gene_expression of Eif2ak3 2 0.43 1.28 0.79
193 INT302771 Negative_regulation of Mapkapk5 1 0.23 1.46 0.77
194 INT118078 Phosphorylation of APP 10 0.79 2.5 0.76
195 INT99820 Negative_regulation of Localization of APP 2 0.37 0.75 0.76
196 INT341172 Regulation of Eif4ebp1 1 0.20 4.42 0.74
197 INT151170 Regulation of Regulation of Akt1 2 0.45 3.28 0.73
198 INT200669 Negative_regulation of AKT2 2 0.42 0.94 0.72
199 INT160736 Negative_regulation of KRT7 9 0.41 10.08 0.68
200 INT112208 Negative_regulation of Gene_expression of App 4 0.59 1.88 0.68
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