GO:0006418

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Name tRNA aminoacylation for protein translation
Categary Process
Go Slim No
Go Link GO:0006418
Unique Molecular Interactions 56
Total Molecular Interactions 68
Total Single Events 438
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tRNA aminoacylation for protein translation. They are ordered first by their pain relevance and then by number of times they were reported for tRNA aminoacylation for protein translation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT197241 Kars Regulation of Localization of Gabrg1 1 0.23 0 1.02
2 INT107596 Binding of PPA1 and OPLL 1 0.00 1.13 0.77
3 INT118396 Nfe2l2 Positive_regulation of Gene_expression of Cars 1 0.05 0.26 0.47
4 INT346913 Binding of Kars and Positive_regulation of Gene_expression of Ros1 1 0.03 1.25 0.46
5 INT135389 4930519F16Rik Positive_regulation of Pars2 1 0.01 0.78 0.45
6 INT346914 Binding of Kars and Positive_regulation of Gene_expression of Car2 1 0.05 1.24 0.45
7 INT180718 Binding of SARS and ACE2 3 0.12 7.76 0.25
8 INT197235 Binding of Grik1 and Kars 1 0.32 0.1 0.25
9 INT197237 Binding of Kars and Grik4 1 0.17 0.1 0.25
10 INT197232 Binding of Grik5 and Kars 1 0.17 0.1 0.25
11 INT334256 Binding of Tlr9 and Iars 1 0.02 0.68 0.24
12 INT297376 Binding of RARS and Rxra 1 0.01 3.27 0.24
13 INT334269 Iars Negative_regulation of Gene_expression of IFNA1 1 0.03 0.62 0.23
14 INT213814 F3 Positive_regulation of Pars2 1 0.01 0.58 0.21
15 INT216705 Binding of MARS and P2RY1 1 0.06 0 0.2
16 INT180503 Binding of SARS and PSMD6 1 0.22 2.44 0.16
17 INT138321 PPA1 Positive_regulation of Gene_expression of PTGS2 1 0.02 0.09 0.14
18 INT173200 PPA1 Positive_regulation of Myc 1 0.08 0.5 0.12
19 INT173122 PPA1 Positive_regulation of HRAS 1 0.08 0.5 0.12
20 INT173125 PPA1 Positive_regulation of JUN 1 0.06 0.5 0.12
21 INT173119 PPA1 Regulation of IER3 1 0.00 0.36 0.12
22 INT180715 Binding of SARS and CLEC4M 2 0.12 2.92 0.11
23 INT220289 MARS Regulation of CEBPZ 1 0.02 0.93 0.11
24 INT173124 PPA1 Regulation of ZFP37 1 0.00 0.44 0.1
25 INT220288 MARS Regulation of AFM 1 0.06 1.14 0.08
26 INT220290 Binding of AFM and MARS 1 0.05 1.09 0.07
27 INT313804 Binding of VARS and YOD1 1 0.00 0.49 0.06
28 INT285383 Cars Regulation of Regulation of Sult1a1 1 0.01 0 0.06
29 INT353912 Binding of ACLY and LARS 1 0.25 0.28 0.06
30 INT301496 PPA1 Negative_regulation of CYP4F3 1 0.01 0.69 0.05
31 INT308649 Binding of Ppp1r13b and Iars 1 0.01 0.29 0.04
32 INT250803 Binding of SARS and MBL3P 1 0.09 1.7 0.04
33 INT246838 Iars Positive_regulation of Phosphorylation of Ins1 1 0.05 0.86 0.03
34 INT246835 Iars Positive_regulation of Ins1 1 0.06 0.86 0.03
35 INT201379 RARS Regulation of Gene_expression of CPOX 1 0.04 0.23 0.03
36 INT235626 Binding of IARS and INS 1 0.08 0.15 0
37 INT335214 Binding of ESR1 and RARS 1 0.08 0.92 0
38 INT225548 Asc2 Positive_regulation of Positive_regulation of Rars 1 0.08 0 0
39 INT180719 Binding of SARS and MMEL1 1 0.00 1.09 0
40 INT283543 Binding of GARS and Setx 1 0.01 3.71 0
41 INT225586 Rbm39 Positive_regulation of Rars 1 0.08 0 0
42 INT301669 PPA1 Positive_regulation of Ppara 1 0.02 0.14 0
43 INT189330 PPA1 Positive_regulation of ERCC6 1 0.10 0 0
44 INT225594 Ncoa6 Positive_regulation of Positive_regulation of Rars 1 0.28 0 0
45 INT335216 RARS Negative_regulation of Binding of ESR1 1 0.10 0.92 0
46 INT231521 Binding of IARS and POMT1 1 0.03 0.72 0
47 INT235625 INS Positive_regulation of Positive_regulation of IARS 1 0.10 0.26 0
48 INT283544 Binding of GARS and Bscl2 1 0.01 1.74 0
49 INT189331 PPA1 Negative_regulation of Phosphorylation of ERCC6 1 0.06 0 0
50 INT283533 Binding of GARS and SPG19 1 0.00 1.72 0
51 INT180750 Binding of SARS and Emid1 1 0.25 3.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for tRNA aminoacylation for protein translation. They are ordered first by their pain relevance and then by number of times they were reported in tRNA aminoacylation for protein translation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86792 Gene_expression of Kars 17 0.77 4.24 8.58
2 INT197229 Positive_regulation of Kars 5 0.54 1.89 4.81
3 INT117495 Gene_expression of Pars2 13 0.38 7.93 4.24
4 INT197220 Positive_regulation of Gene_expression of Kars 3 0.39 0.29 3.15
5 INT40772 Localization of Iars 7 0.25 0.49 2.75
6 INT197225 Regulation of Positive_regulation of Kars 1 0.35 0 2.56
7 INT207082 Positive_regulation of Pars2 10 0.14 5.45 2.22
8 INT40775 Positive_regulation of Localization of Iars 1 0.14 0 1.5
9 INT40771 Positive_regulation of Iars 6 0.36 2.1 1.33
10 INT131816 Negative_regulation of Pars2 1 0.19 1.05 1.31
11 INT37726 Negative_regulation of SARS 5 0.36 4.1 1.26
12 INT31397 Gene_expression of Iars 7 0.51 4.16 1.24
13 INT171512 Gene_expression of RARS 4 0.45 2.56 1.17
14 INT206467 Gene_expression of IARS 11 0.33 6.65 0.93
15 INT197223 Localization of Kars 3 0.58 0.73 0.89
16 INT197221 Negative_regulation of Kars 2 0.33 0.69 0.87
17 INT180534 Gene_expression of SARS 40 0.59 35.47 0.81
18 INT11779 Binding of Iars 4 0.26 1.38 0.78
19 INT197211 Binding of Kars 2 0.29 1.3 0.78
20 INT118389 Gene_expression of Cars 2 0.13 0.68 0.72
21 INT116249 Positive_regulation of LARS 6 0.39 4.16 0.71
22 INT180743 Binding of SARS 12 0.23 17.94 0.62
23 INT180528 Positive_regulation of SARS 12 0.30 18.6 0.53
24 INT195984 Localization of LARS 3 0.42 0.93 0.53
25 INT40774 Negative_regulation of Localization of Iars 1 0.12 0 0.51
26 INT67783 Negative_regulation of LARS 3 0.37 1.23 0.5
27 INT213778 Positive_regulation of Positive_regulation of Pars2 1 0.10 1.4 0.5
28 INT40773 Regulation of Localization of Iars 1 0.07 0 0.49
29 INT170239 Gene_expression of VARS 12 0.07 2.15 0.47
30 INT173170 Gene_expression of PPA1 5 0.06 3.11 0.47
31 INT135387 Localization of Pars2 1 0.58 0.79 0.46
32 INT118391 Positive_regulation of Gene_expression of Cars 1 0.05 0.26 0.46
33 INT197212 Regulation of Kars 1 0.35 0.1 0.43
34 INT207101 Regulation of Pars2 1 0.10 0.76 0.43
35 INT135385 Binding of Pars2 1 0.24 0.73 0.41
36 INT143299 Transcription of Pars2 2 0.21 0.79 0.4
37 INT213775 Regulation of Gene_expression of Pars2 1 0.13 0.88 0.4
38 INT246823 Phosphorylation of Iars 7 0.31 2.77 0.38
39 INT201389 Positive_regulation of RARS 3 0.27 2.58 0.38
40 INT216267 Binding of IARS 4 0.32 5.34 0.37
41 INT148527 Positive_regulation of Cars 1 0.49 0.18 0.37
42 INT220295 Gene_expression of MARS 6 0.47 4.74 0.35
43 INT153494 Regulation of Gene_expression of Cars 1 0.09 0.43 0.27
44 INT511 Positive_regulation of IARS 7 0.45 3.58 0.26
45 INT202256 Binding of VARS 2 0.03 0 0.25
46 INT47648 Negative_regulation of Iars 3 0.16 1.42 0.24
47 INT308616 Positive_regulation of Phosphorylation of Iars 1 0.15 0.63 0.24
48 INT346909 Positive_regulation of Positive_regulation of Kars 1 0.35 1.39 0.24
49 INT323921 Positive_regulation of Gene_expression of IARS 1 0.25 0.83 0.21
50 INT110388 Positive_regulation of PPA1 3 0.05 3.12 0.2
51 INT220296 Negative_regulation of MARS 3 0.29 1.43 0.2
52 INT213768 Positive_regulation of Gene_expression of Pars2 1 0.10 0.55 0.19
53 INT175834 Localization of SARS 6 0.39 6.23 0.17
54 INT219484 Positive_regulation of MARS 5 0.46 2.79 0.17
55 INT173181 Regulation of Gene_expression of PPA1 1 0.04 0.83 0.17
56 INT78372 Localization of PPA1 1 0.42 0.43 0.14
57 INT308611 Negative_regulation of Gene_expression of Iars 1 0.14 1.78 0.13
58 INT9219 Gene_expression of LARS 3 0.59 0.87 0.12
59 INT129427 Transcription of PPA1 1 0.00 0.24 0.12
60 INT173176 Binding of PPA1 1 0.04 0.09 0.12
61 INT220293 Regulation of MARS 8 0.31 7.79 0.11
62 INT173174 Positive_regulation of Positive_regulation of PPA1 1 0.05 0.96 0.11
63 INT180738 Regulation of SARS 7 0.23 7.75 0.1
64 INT173161 Regulation of PPA1 1 0.04 0.44 0.1
65 INT201391 Binding of RARS 1 0.24 0.07 0.1
66 INT41751 Negative_regulation of PPA1 1 0.00 0.13 0.09
67 INT195087 Protein_catabolism of Pars2 1 0.12 0.83 0.09
68 INT173195 Positive_regulation of Gene_expression of PPA1 1 0.04 0.44 0.07
69 INT291272 Negative_regulation of Positive_regulation of IARS 1 0.04 0.46 0.07
70 INT91101 Gene_expression of GARS 1 0.32 0.95 0.07
71 INT180740 Transcription of SARS 2 0.32 3.45 0.06
72 INT285351 Binding of Cars 1 0.21 0 0.06
73 INT180744 Positive_regulation of Gene_expression of SARS 6 0.29 7.79 0.05
74 INT220294 Positive_regulation of Gene_expression of MARS 3 0.35 2.45 0.05
75 INT217252 Regulation of Gene_expression of SARS 1 0.26 0 0.05
76 INT220291 Binding of MARS 1 0.25 0.75 0.05
77 INT89402 Phosphorylation of IARS 1 0.61 0.6 0.04
78 INT283541 Binding of GARS 1 0.01 3.33 0.04
79 INT246574 Protein_catabolism of PPA1 1 0.01 0.62 0.03
80 INT206466 Regulation of IARS 2 0.17 0.56 0
81 INT310752 Binding of LARS 2 0.42 1.15 0
82 INT235631 Negative_regulation of IARS 1 0.11 0.33 0
83 INT353682 Positive_regulation of Protein_catabolism of SARS 1 0.02 0.66 0
84 INT225417 Positive_regulation of Rars 1 0.34 0 0
85 INT353914 Positive_regulation of Gene_expression of LARS 1 0.44 0.22 0
86 INT353679 Protein_catabolism of SARS 1 0.02 0.66 0
87 INT191737 Negative_regulation of Positive_regulation of SARS 1 0.25 1.14 0
88 INT323093 Regulation of Phosphorylation of Iars 1 0.13 0.17 0
89 INT308348 Positive_regulation of Gene_expression of Iars 1 0.23 0.25 0
90 INT189360 Phosphorylation of PPA1 1 0.10 0 0
91 INT219479 Positive_regulation of GARS 1 0.39 0.3 0
92 INT180741 Negative_regulation of Gene_expression of SARS 1 0.22 0.92 0
93 INT256514 Localization of Rars 1 0.26 0.11 0
94 INT152687 Regulation of LARS 1 0.23 0 0
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