GO:0006446

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Name regulation of translational initiation
Categary Process
Go Slim No
Go Link GO:0006446
Unique Molecular Interactions 32
Total Molecular Interactions 50
Total Single Events 321
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of translational initiation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of translational initiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT341218 Binding of Eif4e and Eif4ebp1 1 0.19 2.65 1.23
2 INT38549 Binding of VIP and EIF1 1 0.06 0 0.36
3 INT341214 Tas2r130 Positive_regulation of Phosphorylation of Eif4ebp1 1 0.00 0.68 0.31
4 INT58445 Binding of EIF3K and Klf6 1 0.00 0 0.2
5 INT273902 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.56 0.15
6 INT341235 Negative_regulation of INS Positive_regulation of Phosphorylation of Eif4ebp1 1 0.01 0.24 0.09
7 INT308225 Alb Positive_regulation of Binding of EIF4G2 1 0.02 0.33 0.09
8 INT341220 Eif4e Positive_regulation of Eif4ebp1 1 0.20 0.42 0.06
9 INT341219 Binding of Eif4ebp1 and Eif4g3 1 0.05 0 0.06
10 INT341231 INS Positive_regulation of Phosphorylation of Eif4ebp1 1 0.01 0.13 0.04
11 INT341236 ROS1 Positive_regulation of Phosphorylation of Eif4ebp1 1 0.02 0.25 0.04
12 INT348885 Atpif1 Positive_regulation of EIF5B 1 0.01 0.08 0.04
13 INT341225 Negative_regulation of Binding of Eif4e and Eif4ebp1 1 0.17 0.14 0.03
14 INT302493 Binding of AGRP and IMPACT 1 0.25 0.53 0
15 INT204997 Ppp1r15b Regulation of Mavs 1 0.00 0.87 0
16 INT211779 Binding of EIF4G1 and NTSR1 1 0.02 0 0
17 INT341232 Binding of EIF4A2 and Eif4e 1 0.06 0 0
18 INT186905 EIF1 Regulation of Gene_expression of IL8 1 0.07 0 0
19 INT186904 EIF1 Positive_regulation of Localization of IL8 1 0.06 0 0
20 INT205388 Binding of HSPB1 and MME 1 0.22 1.36 0
21 INT341240 Binding of EIF4E and Eif4ebp1 1 0.04 0.5 0
22 INT341221 Eif4e Regulation of Binding of Eif4ebp1 1 0.18 0 0
23 INT341227 Mtor Regulation of Phosphorylation of Eif4ebp1 1 0.02 0.19 0
24 INT204995 Ppp1r15b Regulation of Gene_expression of Pink1 1 0.01 0.97 0
25 INT341216 Regulation of Binding of Eif4e and Eif4ebp1 1 0.11 0 0
26 INT186906 EIF1 Positive_regulation of Localization of LDHA 1 0.03 0 0
27 INT186902 EIF1 Positive_regulation of Gene_expression of IL8 1 0.08 0 0
28 INT186907 EIF1 Regulation of DEFB1 1 0.00 0 0
29 INT341233 Positive_regulation of Binding of EIF4E and Eif4ebp1 1 0.06 0.5 0
30 INT186908 EIF1 Positive_regulation of Transcription of IL8 1 0.06 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of translational initiation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of translational initiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT228659 Phosphorylation of Eif4ebp1 10 0.80 27.53 6.87
2 INT211203 Positive_regulation of Gene_expression of IMPACT 1 0.17 2 1.75
3 INT155130 Gene_expression of IMPACT 14 0.58 3.43 1.61
4 INT228661 Negative_regulation of Phosphorylation of Eif4ebp1 6 0.41 2.25 1.16
5 INT32474 Gene_expression of EIF3K 8 0.12 1.64 1
6 INT186924 Gene_expression of EIF1 25 0.08 2.64 0.97
7 INT341181 Positive_regulation of Phosphorylation of Eif4ebp1 1 0.30 4.99 0.86
8 INT341172 Regulation of Eif4ebp1 1 0.20 4.42 0.74
9 INT276424 Negative_regulation of IMPACT 4 0.32 2.6 0.72
10 INT55885 Positive_regulation of EIF1 3 0.43 1.17 0.71
11 INT70216 Gene_expression of HSPB1 8 0.78 4.81 0.64
12 INT194981 Regulation of IMPACT 5 0.38 1.47 0.63
13 INT174903 Binding of IMPACT 3 0.32 2.12 0.49
14 INT341203 Binding of Eif4ebp1 1 0.21 0.86 0.46
15 INT308847 Regulation of Phosphorylation of Eif4ebp1 3 0.27 2.11 0.41
16 INT186912 Protein_catabolism of EIF1 1 0.10 1.88 0.39
17 INT228660 Negative_regulation of Eif4ebp1 2 0.41 1.19 0.32
18 INT32476 Regulation of Gene_expression of EIF3K 2 0.03 1.05 0.31
19 INT105142 Positive_regulation of HSPB1 3 0.70 1.08 0.3
20 INT228662 Gene_expression of Eif4ebp1 2 0.65 0.91 0.26
21 INT171685 Phosphorylation of HSPB1 2 0.69 0.39 0.24
22 INT32475 Positive_regulation of Gene_expression of EIF3K 1 0.05 0.07 0.2
23 INT194986 Positive_regulation of IMPACT 4 0.33 0.63 0.18
24 INT164567 Negative_regulation of EIF1 2 0.01 0.19 0.18
25 INT341187 Regulation of Binding of Eif4ebp1 1 0.12 0.19 0.17
26 INT105143 Binding of HSPB1 1 0.36 0.54 0.17
27 INT186911 Regulation of EIF1 1 0.03 0 0.16
28 INT70215 Positive_regulation of Gene_expression of HSPB1 2 0.68 0.65 0.15
29 INT20628 Positive_regulation of EIF3K 2 0.07 0.23 0.15
30 INT105141 Regulation of Gene_expression of HSPB1 1 0.45 0.36 0.14
31 INT353246 Gene_expression of EIF4G1 1 0.06 1.23 0.14
32 INT260700 Regulation of Gene_expression of EIF1 1 0.01 0 0.14
33 INT186917 Localization of EIF1 1 0.08 0.41 0.12
34 INT142966 Regulation of EIF3K 2 0.06 0.76 0.09
35 INT341199 Negative_regulation of Gene_expression of Eif4ebp1 1 0.19 0.18 0.09
36 INT341193 Positive_regulation of Gene_expression of Eif4ebp1 1 0.22 0.17 0.09
37 INT142967 Regulation of Regulation of EIF3K 1 0.00 0.76 0.09
38 INT308214 Binding of EIF4G2 1 0.35 0.32 0.08
39 INT341171 Positive_regulation of Eif4ebp1 1 0.22 0.48 0.07
40 INT348864 Gene_expression of EIF5B 1 0.07 0.27 0.07
41 INT20635 Positive_regulation of Positive_regulation of EIF3K 1 0.07 0.14 0.06
42 INT341196 Positive_regulation of Localization of Eif4ebp1 1 0.30 0.26 0.05
43 INT176591 Positive_regulation of EIF5B 1 0.05 0.31 0.05
44 INT303037 Transcription of IMPACT 2 0.49 0.69 0.04
45 INT194982 Localization of IMPACT 1 0.53 0.16 0.04
46 INT303036 Negative_regulation of Transcription of IMPACT 1 0.17 0 0.04
47 INT341207 Localization of Eif4ebp1 1 0.35 0.13 0.03
48 INT341201 Negative_regulation of Binding of Eif4ebp1 1 0.19 0.23 0.03
49 INT186929 Positive_regulation of Gene_expression of EIF1 1 0.05 0.21 0
50 INT303322 Positive_regulation of Phosphorylation of EIF4A2 1 0.08 0.16 0
51 INT211840 Protein_catabolism of EIF4G1 1 0.35 0.13 0
52 INT211836 Binding of EIF4G1 1 0.12 0.07 0
53 INT186927 Transcription of EIF1 1 0.07 0 0
54 INT304390 Transcription of EIF3K 1 0.08 0.11 0
55 INT213938 Negative_regulation of Gene_expression of HSPB1 1 0.57 0.38 0
56 INT204977 Positive_regulation of Ppp1r15b 1 0.01 0.49 0
57 INT303318 Phosphorylation of EIF4A2 1 0.11 0.16 0
58 INT341209 Binding of EIF4A2 1 0.06 0 0
59 INT186928 Binding of EIF1 1 0.04 0.22 0
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