GO:0006464

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Name protein modification process
Categary Process
Go Slim Yes
Go Link GO:0006464
Unique Molecular Interactions 429
Total Molecular Interactions 548
Total Single Events 4184
Pain Genes Associated 49

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein modification process. They are ordered first by their pain relevance and then by number of times they were reported for protein modification process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT44716 Binding of ABL2 and PDYN 2 0.40 0.66 4.77
2 INT202959 Binding of BAG3 and MCRS1 1 0.11 7.46 3.14
3 INT14687 Binding of Penk and Ppt1 1 0.41 0 2.46
4 INT60867 Binding of G2e3 and Gpm6a 2 0.01 0.1 1.93
5 INT68272 Binding of Oprd1 and G2e3 1 0.00 0.11 1.93
6 INT167320 Binding of CPE and OPRM1 1 0.14 0.63 1.77
7 INT24689 Binding of PLAT and Serpine1 1 0.00 3.77 1.64
8 INT342993 PHEX Regulation of Protein_catabolism of SFTPA1 1 0.00 2.84 1.58
9 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44
10 INT167528 Ppt1 Negative_regulation of Gene_expression of Tac4 1 0.06 0.49 1.39
11 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 0.26 0.49 1.38
12 INT305408 Binding of KCNMA1 and ST8SIA2 1 0.01 0.09 1.24
13 INT25026 PLOD1 Regulation of FSHR 4 0.19 0.38 1.15
14 INT202960 Binding of MCRS1 and CPP 1 0.14 2.49 1.13
15 INT101715 PLAT Positive_regulation of NFKB1 2 0.11 0.99 1.09
16 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08
17 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08
18 INT153039 Binding of G2e3 and LOC100360318 1 0.00 0 1.01
19 INT4916 Binding of Pax3 and Wdyhv1 1 0.00 0 0.98
20 INT70802 Ngf Regulation of Ppt1 1 0.21 0.39 0.93
21 INT61698 G2e3 Regulation of Localization of Abat 1 0.05 0 0.88
22 INT44442 GNRH1 Positive_regulation of Localization of PLOD1 3 0.50 0.78 0.86
23 INT305406 Binding of CAV3 and ST8SIA2 1 0.16 0 0.86
24 INT34740 BID Regulation of Gene_expression of PLOD1 1 0.01 0 0.83
25 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
26 INT104749 Ugt1a1 Regulation of Positive_regulation of G2e3 1 0.00 0.07 0.77
27 INT125523 PLAT Positive_regulation of GDF15 1 0.13 1.33 0.75
28 INT202967 MCRS1 Negative_regulation of CPP 2 0.14 2.2 0.73
29 INT128684 Binding of TGM1 and RETNLB 1 0.00 2.46 0.72
30 INT169293 PTPLA Positive_regulation of AKT1 1 0.10 0.15 0.64
31 INT45780 GNRH1 Positive_regulation of PLOD1 3 0.07 1.02 0.63
32 INT278695 MTX1 Negative_regulation of Phosphorylation of AKT1 1 0.04 0.81 0.62
33 INT73402 Binding of Oprl1 and Wdyhv1 1 0.00 0 0.61
34 INT85489 IRF6 Negative_regulation of PLOD1 1 0.01 0.16 0.61
35 INT85488 Negative_regulation of IRF6 Negative_regulation of PLOD1 1 0.01 0.16 0.61
36 INT101718 PLAT Positive_regulation of Transcription of OPRM1 1 0.22 0.06 0.61
37 INT45781 Regulation of GNRH1 Positive_regulation of PLOD1 1 0.06 0.16 0.61
38 INT35154 PLOD1 Regulation of PRL 2 0.17 0 0.6
39 INT101719 PLAT Positive_regulation of NFYC 1 0.13 0.1 0.6
40 INT101717 PLAT Positive_regulation of JUND 1 0.17 0.1 0.59
41 INT37034 PLAT Positive_regulation of PLDN 1 0.08 0.15 0.58
42 INT345303 MMP15 Positive_regulation of MMP13 1 0.00 1.18 0.58
43 INT37035 PLAT Negative_regulation of ODC1 1 0.45 0.15 0.58
44 INT202972 Positive_regulation of MCRS1 Negative_regulation of CPP 1 0.16 1.64 0.57
45 INT202961 MCRS1 Negative_regulation of STC2 1 0.00 1.63 0.57
46 INT345302 MMP15 Positive_regulation of MMP2 1 0.06 1.17 0.57
47 INT201944 CXCL10 Positive_regulation of Phosphorylation of AKT1 1 0.09 0.79 0.55
48 INT23485 HBE1 Positive_regulation of Localization of PLOD1 1 0.04 0 0.54
49 INT69177 UBA7 Negative_regulation of Igk 1 0.00 0.15 0.54
50 INT23482 HBE1 Positive_regulation of PLOD1 1 0.04 0 0.53
51 INT70244 POMC Positive_regulation of Localization of PLOD1 1 0.21 0 0.53
52 INT23484 Positive_regulation of HBE1 Positive_regulation of PLOD1 1 0.04 0 0.53
53 INT69179 Binding of UBA7 and Adarb1 1 0.00 0.16 0.53
54 INT97952 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1 1 0.03 0.72 0.51
55 INT202957 CPP Negative_regulation of MCRS1 1 0.14 1.53 0.51
56 INT97951 ST3GAL3 Positive_regulation of AKT1 1 0.04 0.7 0.5
57 INT39248 NPL Regulation of PLOD1 1 0.14 0.16 0.49
58 INT114593 Il1b Positive_regulation of Gene_expression of Ppt1 1 0.05 0.06 0.48
59 INT180958 Binding of F13A1 and PLAT 2 0.03 2.16 0.47
60 INT202969 Positive_regulation of SGSM3 Positive_regulation of MCRS1 1 0.02 1.22 0.47
61 INT202964 SGSM3 Positive_regulation of MCRS1 1 0.03 1.21 0.47
62 INT162932 TXNRD1 Negative_regulation of Phosphorylation of AKT1 1 0.14 1.01 0.47
63 INT162929 NQO1 Negative_regulation of Phosphorylation of AKT1 1 0.41 1 0.46
64 INT168699 Binding of Nedd4 and Tyr 1 0.02 0.45 0.46
65 INT22674 Binding of SERPINE1 and PLAT 7 0.04 0.65 0.45
66 INT63152 Ppt1 Regulation of Gene_expression of Pd 1 0.01 0 0.43
67 INT23481 POMC Regulation of Localization of PLOD1 1 0.20 0 0.42
68 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
69 INT125520 PLAT Positive_regulation of Gene_expression of GDF15 1 0.13 0.74 0.42
70 INT76154 Binding of NCOR2 and Negative_regulation of Localization of PLOD1 1 0.02 0 0.42
71 INT160048 INPPL1 Regulation of Gene_expression of AKT1 1 0.28 0.6 0.42
72 INT121851 AKT1 Regulation of ROS1 1 0.16 0.52 0.41
73 INT114601 Il1b Positive_regulation of Transcription of Ppt1 1 0.35 0.1 0.41
74 INT121848 AKT1 Regulation of CASP8 1 0.18 0.52 0.41
75 INT121854 AKT1 Regulation of BID 1 0.17 0.52 0.41
76 INT108197 AKT1 Regulation of JUN 1 0.29 0.25 0.4
77 INT121853 Gene_expression of ROS1 Negative_regulation of AKT1 1 0.25 0.49 0.4
78 INT305407 Binding of ST8SIA2 and ANTXR1 1 0.00 0.09 0.38
79 INT89386 INS Positive_regulation of Phosphorylation of AKT1 3 0.43 1.48 0.36
80 INT299288 AKT1 Positive_regulation of RPTOR 1 0.34 0.05 0.36
81 INT97043 Binding of G2e3 and Hist1h3g 1 0.01 0.5 0.36
82 INT176135 AKT1 Regulation of Localization of CYCS 1 0.43 2.16 0.35
83 INT70935 Nts Regulation of SEPHS1 1 0.00 0.38 0.34
84 INT43388 OPRM1 Positive_regulation of Localization of PLOD1 1 0.27 0 0.34
85 INT344238 MCRS1 Regulation of TREX1 1 0.08 1.02 0.34
86 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33
87 INT214854 SERPINE1 Positive_regulation of PLAT 1 0.24 0.42 0.33
88 INT337412 AKT3 Negative_regulation of Localization of AKT2 1 0.09 0.5 0.32
89 INT337418 AKT2 Negative_regulation of Localization of AKT3 1 0.09 0.5 0.32
90 INT31042 Ghrh Positive_regulation of Localization of PLOD1 1 0.08 0 0.32
91 INT31039 Gnrh1 Negative_regulation of Localization of PLOD1 1 0.05 0 0.32
92 INT337410 AKT3 Negative_regulation of AKT1 1 0.09 0.49 0.32
93 INT337414 AKT2 Negative_regulation of AKT1 1 0.10 0.5 0.32
94 INT15685 Binding of PLAT and Serpine1 3 0.36 1.01 0.31
95 INT31043 Ghrh Positive_regulation of PLOD1 1 0.03 0 0.31
96 INT299307 AKT1 Positive_regulation of Positive_regulation of AKT1S1 1 0.10 0 0.3
97 INT299289 AKT1 Positive_regulation of Positive_regulation of TSC2 1 0.17 0 0.3
98 INT191240 SAE1 Regulation of Localization of INS 1 0.08 1.15 0.3
99 INT247083 Binding of F5 and PLAT 1 0.03 0.88 0.29
100 INT35079 CRH Negative_regulation of Localization of PLOD1 1 0.06 0 0.29
101 INT89911 PLOD1 Positive_regulation of Localization of PRL 1 0.12 0 0.29
102 INT89912 PLOD1 Positive_regulation of Localization of GH1 1 0.04 0 0.29
103 INT89897 PLOD1 Positive_regulation of Localization of POMC 1 0.13 0 0.29
104 INT291202 Positive_regulation of INS Positive_regulation of AKT1 1 0.01 0.76 0.29
105 INT109098 Binding of ABL2 and PON1 1 0.36 1.32 0.28
106 INT67768 NPL Positive_regulation of PLOD1 1 0.30 0 0.28
107 INT309298 Binding of NA and ST8SIA2 1 0.00 0 0.28
108 INT67769 Regulation of NPL Positive_regulation of PLOD1 1 0.17 0 0.28
109 INT44759 Negative_regulation of PLAT Positive_regulation of ODC1 1 0.27 0 0.27
110 INT44760 PLAT Positive_regulation of ODC1 1 0.29 0 0.27
111 INT125522 PLAT Regulation of Gene_expression of GDF15 1 0.08 0.46 0.26
112 INT125514 Positive_regulation of PRKDC Positive_regulation of Positive_regulation of NFKB1 1 0.07 0.44 0.26
113 INT125513 PLAT Positive_regulation of Transcription of GDF15 1 0.12 0.44 0.26
114 INT125517 Negative_regulation of PLAT Positive_regulation of GDF15 1 0.12 0.46 0.25
115 INT55641 Binding of CHRM1 and Adra2a 1 0.00 0 0.24
116 INT125519 Regulation of PLAT Positive_regulation of NFKB1 1 0.07 0.44 0.24
117 INT140376 TGM1 Positive_regulation of Rhoa 1 0.01 0 0.24
118 INT49697 ST8SIA4 Regulation of Prl 1 0.01 0.26 0.23
119 INT37033 PLAT Negative_regulation of PLDN 1 0.08 0.07 0.23
120 INT49694 ST8SIA4 Positive_regulation of Prl 1 0.01 0.26 0.23
121 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23
122 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22
123 INT224431 TNF Positive_regulation of Gene_expression of FBXO2 1 0.47 0.35 0.22
124 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
125 INT70082 Binding of APP and TGM1 1 0.00 1.22 0.22
126 INT224452 Il1 Positive_regulation of Gene_expression of FBXO2 1 0.37 0.35 0.22
127 INT193033 Binding of CHRM1 and EGF 1 0.01 1.96 0.22
128 INT295430 BRD2 Positive_regulation of PLOD1 1 0.02 0.33 0.22
129 INT35151 PLOD1 Regulation of PGR 1 0.09 0 0.21
130 INT35149 PLOD1 Regulation of GHRH 1 0.02 0 0.21
131 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21
132 INT274578 Binding of ABL1 and PSTPIP1 1 0.07 1.55 0.21
133 INT120716 Binding of AKT1 and TEP1 1 0.05 0.46 0.21
134 INT35150 PLOD1 Regulation of LHB 1 0.09 0 0.21
135 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2
136 INT157083 Ghrl Regulation of Gene_expression of Ppt1 1 0.40 0 0.2
137 INT25053 Crh Regulation of PLOD1 1 0.11 0 0.19
138 INT32360 DBI Positive_regulation of Localization of PLOD1 1 0.05 0 0.19
139 INT121632 PTGER1 Positive_regulation of TGM1 1 0.00 0.67 0.19
140 INT197618 Binding of Esr1 and Ppt1 1 0.01 0 0.18
141 INT247082 Binding of PLAT and PTBP1 1 0.14 0.59 0.18
142 INT191241 SST Regulation of SAE1 1 0.05 0.89 0.18
143 INT121631 PDGFD Positive_regulation of TGM1 1 0.01 0.68 0.18
144 INT298192 EGFR Positive_regulation of AKT1 1 0.10 0.65 0.18
145 INT121582 AKT1 Regulation of Gene_expression of GDF15 1 0.21 0.4 0.18
146 INT318324 Binding of AKT1 and PRKCA 1 0.03 0.63 0.18
147 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
148 INT306261 AKT2 Negative_regulation of Phosphorylation of FOXO1 1 0.25 0.41 0.17
149 INT105334 PTGER1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.66 0.17
150 INT176134 AKT1 Regulation of Gene_expression of BIRC3 1 0.08 1.09 0.17
151 INT12521 Binding of PLOD1 and POMC 1 0.26 1.96 0.17
152 INT277013 PLAT Positive_regulation of Gene_expression of F13A1 1 0.02 0.31 0.17
153 INT25050 Crh Negative_regulation of PLOD1 1 0.11 0 0.17
154 INT168700 Positive_regulation of Binding of Nedd4 and Tyr 1 0.03 0.19 0.17
155 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.91 0.16
156 INT295433 Binding of PLOD1 and SCN5A 1 0.07 0.25 0.16
157 INT270416 PLAT Negative_regulation of Positive_regulation of PLG 1 0.00 0.48 0.15
158 INT248147 PLAT Positive_regulation of Gene_expression of CPOX 1 0.00 0.51 0.15
159 INT241844 Positive_regulation of GNRH1 Positive_regulation of Localization of PLOD1 1 0.13 0.08 0.15
160 INT70090 TGM1 Positive_regulation of Binding of Ache 1 0.03 0.59 0.15
161 INT49681 ST8SIA4 Positive_regulation of Localization of GH1 1 0.01 0 0.15
162 INT188249 PLAT Positive_regulation of PLG 2 0.10 0.86 0.14
163 INT249829 CHI3L1 Positive_regulation of AKT1 1 0.47 0.69 0.14
164 INT298639 GDE1 Negative_regulation of AKT1 1 0.00 1.14 0.14
165 INT82802 Binding of ABL2 and POMC 1 0.00 0 0.14
166 INT211860 PLOD1 Regulation of AGRP 1 0.07 0.15 0.14
167 INT350204 Binding of CAP1 and QPCT 1 0.06 0 0.13
168 INT254133 PLEC Regulation of MCRS1 1 0.03 0.33 0.13
169 INT278583 Ppt1 Negative_regulation of Gene_expression of Atp6v1e1 1 0.05 0 0.13
170 INT302156 AKT1 Positive_regulation of E2F2 1 0.02 0.88 0.13
171 INT299310 RPTOR Positive_regulation of AKT1 1 0.30 0 0.12
172 INT284891 FSHR Positive_regulation of Gene_expression of PLOD1 2 0.03 1.32 0.11
173 INT27814 CD2AP Positive_regulation of PADI1 1 0.19 0.06 0.11
174 INT50903 Ppt1 Regulation of Tac4 1 0.18 0 0.11
175 INT105338 Prkaca Positive_regulation of AKT1 1 0.04 0.93 0.11
176 INT70084 Negative_regulation of Binding of APP and TGM1 1 0.00 0.61 0.11
177 INT350736 PRKDC Negative_regulation of CA2 1 0.02 0.16 0.11
178 INT70083 TGM1 Positive_regulation of Binding of APP 1 0.00 0.61 0.11
179 INT133362 FABP6 Negative_regulation of LOX 1 0.01 0.08 0.11
180 INT294778 PAM Positive_regulation of Gene_expression of TLR2 1 0.01 0.41 0.11
181 INT350735 PRKDC Negative_regulation of ITPR3 1 0.01 0.16 0.11
182 INT302161 AKT1 Negative_regulation of CASP9 1 0.03 0.87 0.11
183 INT176130 AKT1 Regulation of Gene_expression of COX18 1 0.13 0.82 0.11
184 INT274583 Binding of ABL1 and PSTPIP2 1 0.06 0.79 0.11
185 INT27815 Regulation of CD2AP Positive_regulation of PADI1 1 0.11 0.06 0.11
186 INT50901 Ppt1 Regulation of Transcription of Tac4 1 0.18 0 0.11
187 INT65676 Binding of CGA and PLOD1 3 0.23 1.68 0.1
188 INT324702 PLOD1 Positive_regulation of CGA 1 0.03 1.1 0.1
189 INT226750 Hgs Positive_regulation of Tsg101 1 0.04 0.25 0.1
190 INT116449 POMC Negative_regulation of Localization of PLOD1 1 0.11 0 0.1
191 INT226708 Oprd1 Positive_regulation of Tsg101 1 0.00 0.3 0.1
192 INT226725 Gpbar1 Positive_regulation of Tsg101 1 0.03 0.3 0.1
193 INT294776 PAM Positive_regulation of TLR4 1 0.00 0.17 0.1
194 INT22670 PLAT Positive_regulation of SERPINE1 1 0.03 0.1 0.1
195 INT294777 PAM Positive_regulation of TLR9 1 0.00 0.17 0.1
196 INT343858 Binding of AKT1 and MYD88 1 0.02 0.26 0.1
197 INT22672 Positive_regulation of Binding of SERPINE1 and PLAT 1 0.03 0.1 0.1
198 INT294772 PAM Positive_regulation of TLR2 1 0.00 0.17 0.1
199 INT226733 Vps4a Positive_regulation of Tsg101 1 0.00 0.25 0.1
200 INT114367 Binding of GAD2 and SEPHS1 1 0.11 0.55 0.1

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein modification process. They are ordered first by their pain relevance and then by number of times they were reported in protein modification process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT920 Localization of PLOD1 223 0.81 42.25 78.7
2 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03
3 INT913 Regulation of Localization of PLOD1 71 0.62 8.64 32.72
4 INT7975 Regulation of PLOD1 97 0.62 20.9 30.51
5 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36
6 INT14575 Positive_regulation of Ppt1 60 0.70 9.97 27.4
7 INT1638 Negative_regulation of PLOD1 92 0.59 21.69 26.61
8 INT917 Positive_regulation of Localization of PLOD1 51 0.69 8.53 22.87
9 INT4890 Gene_expression of Ppt1 51 0.77 8.93 21.83
10 INT4894 Transcription of Ppt1 34 0.67 5.93 21.06
11 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
12 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
13 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44
14 INT1642 Negative_regulation of Localization of PLOD1 40 0.58 10.67 17.95
15 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
16 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54
17 INT8794 Negative_regulation of Ppt1 35 0.57 6.44 14.52
18 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78
19 INT24684 Localization of PLAT 30 0.78 26.21 13.56
20 INT60865 Gene_expression of G2e3 20 0.73 2.1 12.76
21 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
22 INT90673 Gene_expression of LOX 66 0.65 69.71 12.18
23 INT58775 Binding of G2e3 10 0.33 0.19 11.52
24 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29
25 INT175554 Binding of MCRS1 21 0.23 25.2 8.59
26 INT90674 Negative_regulation of LOX 56 0.57 38.01 8.58
27 INT24651 Positive_regulation of Transcription of Ppt1 12 0.47 2.88 8.42
28 INT1925 Gene_expression of PLAT 47 0.75 34.76 7.88
29 INT58774 Negative_regulation of G2e3 8 0.38 0.22 7.75
30 INT5774 Regulation of Ppt1 22 0.60 4.97 7.1
31 INT1926 Positive_regulation of PLAT 54 0.66 31.42 6.49
32 INT4888 Positive_regulation of Gene_expression of Ppt1 9 0.54 2.78 5.83
33 INT55353 Negative_regulation of Positive_regulation of Ppt1 9 0.57 0.31 5.37
34 INT89304 Binding of ST8SIA2 12 0.35 0.93 5.23
35 INT51839 Positive_regulation of Localization of PLAT 5 0.49 7.09 4.92
36 INT105336 Regulation of AKT1 52 0.56 32.53 4.89
37 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21
38 INT50022 Positive_regulation of G2e3 10 0.42 0.47 3.72
39 INT55352 Regulation of Gene_expression of Ppt1 9 0.44 0.4 3.51
40 INT184894 Localization of MCRS1 9 0.47 10.04 3.31
41 INT14857 Negative_regulation of Gene_expression of Ppt1 7 0.42 1.16 3.3
42 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19
43 INT1924 Regulation of PLAT 11 0.60 6.3 3.16
44 INT137961 Localization of Ppt1 1 0.64 2.89 3.09
45 INT69727 Gene_expression of QPCT 18 0.65 5.45 3.05
46 INT10136 Negative_regulation of PLAT 23 0.42 11.18 3.02
47 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02
48 INT200670 Gene_expression of AKT2 25 0.75 16.25 3
49 INT305617 Positive_regulation of Gene_expression of MCRS1 1 0.05 7.16 2.91
50 INT25031 Negative_regulation of Gene_expression of PLOD1 14 0.54 3.86 2.89
51 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8
52 INT10101 Binding of PLAT 24 0.36 12.62 2.78
53 INT68444 Gene_expression of CPE 9 0.76 4.6 2.59
54 INT60864 Regulation of G2e3 4 0.21 0.64 2.54
55 INT15201 Positive_regulation of CHRM1 8 0.54 2.14 2.35
56 INT74237 Positive_regulation of Ppt1 3 0.49 2.92 2.32
57 INT12033 Binding of PLOD1 15 0.48 8.04 2.3
58 INT52785 Localization of G2e3 5 0.66 0.33 2.26
59 INT118791 Binding of AKT1 32 0.48 15.51 2.25
60 INT17617 Gene_expression of ABL2 8 0.75 2.73 2.25
61 INT45392 Regulation of CHRM1 3 0.26 0.52 2.25
62 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14
63 INT36534 Negative_regulation of Positive_regulation of PLOD1 5 0.56 1.39 2.14
64 INT7974 Regulation of Gene_expression of PLOD1 6 0.42 0.41 1.99
65 INT7973 Positive_regulation of Regulation of PLOD1 5 0.42 0.42 1.99
66 INT7972 Positive_regulation of Gene_expression of PLOD1 15 0.42 5.73 1.96
67 INT55640 Gene_expression of CHRM1 7 0.44 2.24 1.89
68 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83
69 INT44723 Positive_regulation of ABL2 7 0.49 2.23 1.82
70 INT14862 Negative_regulation of Transcription of Ppt1 3 0.42 0 1.8
71 INT100563 Regulation of Binding of G2e3 1 0.24 0 1.79
72 INT104745 Positive_regulation of Binding of G2e3 1 0.05 0.07 1.77
73 INT10207 Gene_expression of PADI4 22 0.75 23.49 1.74
74 INT23932 Negative_regulation of ST8SIA2 4 0.22 1.26 1.73
75 INT73400 Negative_regulation of Wdyhv1 1 0.00 0 1.73
76 INT144292 Binding of Ppt1 9 0.37 2.02 1.71
77 INT85955 Negative_regulation of Localization of G2e3 2 0.48 0.05 1.63
78 INT25033 Negative_regulation of Negative_regulation of PLOD1 4 0.55 0.36 1.6
79 INT165347 Localization of CPE 2 0.55 0.59 1.56
80 INT2620 Regulation of TGM1 1 0.01 3.27 1.5
81 INT110749 Gene_expression of Ppt1 9 0.34 0.51 1.49
82 INT106831 Negative_regulation of Regulation of CHRM1 1 0.15 0.16 1.49
83 INT340324 Regulation of Ppt1 1 0.13 1.17 1.47
84 INT37886 Positive_regulation of Positive_regulation of PLOD1 1 0.69 0 1.43
85 INT2619 Positive_regulation of TGM1 7 0.49 5.97 1.41
86 INT13730 Negative_regulation of CHRM1 5 0.35 1.78 1.41
87 INT112655 Negative_regulation of PAM 3 0.57 0.97 1.39
88 INT262876 Localization of ST8SIA2 2 0.16 1.41 1.39
89 INT79126 Gene_expression of Wdyhv1 1 0.07 0.8 1.36
90 INT4889 Regulation of Transcription of Ppt1 3 0.35 0.89 1.34
91 INT1651 Positive_regulation of Negative_regulation of PLOD1 4 0.46 0.49 1.33
92 INT53316 Localization of Ppt1 5 0.65 1.59 1.32
93 INT32039 Positive_regulation of CPE 3 0.37 1.92 1.32
94 INT224447 Gene_expression of FBXO2 7 0.75 7.33 1.31
95 INT63532 Positive_regulation of Positive_regulation of Ppt1 2 0.67 0 1.29
96 INT167409 Regulation of Gene_expression of AKT1 8 0.56 4.86 1.23
97 INT305616 Negative_regulation of Gene_expression of MCRS1 1 0.04 3.56 1.23
98 INT70088 Binding of TGM1 9 0.41 5.3 1.22
99 INT112498 Gene_expression of TGM1 18 0.55 10.76 1.21
100 INT125525 Positive_regulation of PRKDC 7 0.45 2.72 1.21
101 INT55351 Positive_regulation of Negative_regulation of Ppt1 3 0.45 0 1.19
102 INT160054 Localization of AKT2 4 0.73 1.93 1.18
103 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17
104 INT135556 Localization of AKT1 38 0.69 12.78 1.17
105 INT118792 Regulation of Positive_regulation of AKT1 8 0.61 3.73 1.15
106 INT105618 Binding of SEPHS1 4 0.27 5.62 1.14
107 INT176147 Regulation of Phosphorylation of AKT1 14 0.41 6.41 1.13
108 INT75698 Negative_regulation of Negative_regulation of Ppt1 1 0.42 1.01 1.11
109 INT75699 Negative_regulation of Ppt1 2 0.58 1.07 1.08
110 INT268379 Gene_expression of ARAF 22 0.16 9.34 1.07
111 INT263822 Positive_regulation of Gene_expression of LOX 8 0.50 11 1.06
112 INT98174 Positive_regulation of Gene_expression of ABL2 1 0.49 1.1 1.05
113 INT202981 Positive_regulation of Binding of MCRS1 3 0.18 4.05 1.02
114 INT262878 Gene_expression of ST8SIA2 7 0.39 4.7 1.01
115 INT305620 Regulation of Positive_regulation of MCRS1 1 0.17 2.48 0.99
116 INT4914 Binding of Wdyhv1 1 0.01 0 0.98
117 INT58755 Binding of PAM 6 0.34 3.09 0.97
118 INT44446 Regulation of Regulation of PLOD1 3 0.38 1.85 0.97
119 INT70248 Positive_regulation of Positive_regulation of G2e3 1 0.13 0.17 0.94
120 INT171636 Negative_regulation of Gene_expression of PLAT 6 0.35 2.92 0.93
121 INT230779 Negative_regulation of Positive_regulation of MCRS1 2 0.04 3.78 0.92
122 INT309303 Positive_regulation of ST8SIA2 2 0.11 0.65 0.91
123 INT160056 Positive_regulation of AKT2 3 0.48 1.43 0.88
124 INT113121 Negative_regulation of Binding of G2e3 1 0.07 0 0.88
125 INT73399 Negative_regulation of Negative_regulation of Wdyhv1 1 0.00 0 0.88
126 INT255622 Positive_regulation of PAM 7 0.18 4.89 0.87
127 INT29636 Localization of PAM 5 0.73 2.1 0.87
128 INT40639 Binding of CHRM1 2 0.26 0.43 0.87
129 INT271605 Regulation of Gene_expression of AKT2 1 0.44 0.81 0.87
130 INT55350 Regulation of Negative_regulation of Ppt1 2 0.60 0 0.86
131 INT263817 Regulation of Negative_regulation of LOX 1 0.33 2.36 0.86
132 INT58759 Positive_regulation of Binding of PAM 1 0.24 0.57 0.85
133 INT128143 Negative_regulation of Gene_expression of G2e3 4 0.09 0 0.82
134 INT33097 Negative_regulation of PHEX 3 0.14 0.41 0.82
135 INT70933 Regulation of SEPHS1 3 0.37 2.56 0.81
136 INT354257 Regulation of Localization of PLAT 1 0.18 0.91 0.79
137 INT87734 Regulation of ARAF 4 0.23 2.44 0.76
138 INT125526 Gene_expression of PRKDC 5 0.58 4 0.74
139 INT157776 Localization of TGM1 2 0.39 2.52 0.74
140 INT134754 Positive_regulation of Gene_expression of PLAT 9 0.49 4.75 0.72
141 INT246524 Binding of QPCT 4 0.05 3.65 0.72
142 INT200669 Negative_regulation of AKT2 2 0.42 0.94 0.72
143 INT69452 Positive_regulation of SEPHS1 3 0.41 1.41 0.71
144 INT212265 Positive_regulation of Gene_expression of CPE 1 0.44 1.26 0.7
145 INT305419 Negative_regulation of Binding of ST8SIA2 1 0.22 0.1 0.69
146 INT299338 Negative_regulation of Regulation of AKT1 2 0.31 2.32 0.68
147 INT27818 Regulation of PADI1 7 0.34 3.77 0.66
148 INT39865 Regulation of Positive_regulation of PLOD1 2 0.27 0.71 0.66
149 INT192321 Regulation of LOX 2 0.33 2.72 0.65
150 INT69283 Gene_expression of PHEX 25 0.75 7.81 0.64
151 INT4785 Gene_expression of PAM 6 0.58 3.47 0.64
152 INT166024 Protein_catabolism of AKT1 5 0.46 2.6 0.64
153 INT299324 Positive_regulation of QPCT 3 0.09 0.12 0.64
154 INT122497 Gene_expression of UBE2S 2 0.58 0.8 0.64
155 INT289197 Localization of QPCT 3 0.15 0.53 0.62
156 INT73401 Binding of Wdyhv1 1 0.00 0 0.61
157 INT320096 Negative_regulation of SAE1 10 0.12 3.85 0.59
158 INT245648 Gene_expression of SEPHS1 5 0.49 4.53 0.59
159 INT171767 Positive_regulation of Gene_expression of MMP15 4 0.38 4.48 0.59
160 INT63533 Negative_regulation of Negative_regulation of Ppt1 1 0.29 0 0.59
161 INT123131 Negative_regulation of Negative_regulation of AKT1 6 0.42 3.23 0.58
162 INT90984 Transcription of PPT2 1 0.08 0.07 0.58
163 INT184345 Gene_expression of Tsg101 10 0.58 3.56 0.57
164 INT263823 Negative_regulation of Gene_expression of LOX 1 0.31 2.49 0.57
165 INT27816 Positive_regulation of PADI1 5 0.41 0.26 0.56
166 INT299323 Negative_regulation of Gene_expression of QPCT 1 0.03 0.65 0.53
167 INT69176 Binding of UBA7 1 0.01 0.14 0.53
168 INT187721 Transcription of PLOD1 4 0.49 4.69 0.51
169 INT187714 Regulation of Negative_regulation of PLOD1 1 0.09 0 0.51
170 INT100099 Regulation of Positive_regulation of Ppt1 1 0.26 0 0.5
171 INT63249 Positive_regulation of Regulation of Ppt1 1 0.49 0 0.5
172 INT271604 Positive_regulation of Gene_expression of AKT2 2 0.49 0.22 0.47
173 INT11363 Regulation of Gene_expression of PLAT 1 0.27 0.87 0.46
174 INT12343 Protein_catabolism of PLAT 2 0.76 0.73 0.44
175 INT258821 Negative_regulation of Localization of PLAT 4 0.57 3.32 0.43
176 INT305618 Regulation of Gene_expression of MCRS1 1 0.04 1.24 0.43
177 INT77493 Regulation of ABL2 1 0.26 0.71 0.42
178 INT160568 Positive_regulation of PADI4 7 0.45 10.5 0.41
179 INT69282 Binding of PHEX 4 0.15 1.43 0.41
180 INT45395 Localization of CHRM1 2 0.73 0.4 0.41
181 INT10102 Regulation of Binding of PLAT 2 0.42 1.24 0.41
182 INT15589 Protein_catabolism of PHEX 3 0.21 0.76 0.4
183 INT70086 Negative_regulation of Binding of TGM1 1 0.50 1.58 0.4
184 INT117662 Gene_expression of ABL1 21 0.69 18.76 0.39
185 INT15588 Regulation of PHEX 4 0.26 1.48 0.39
186 INT182790 Positive_regulation of SAE1 3 0.49 3.18 0.39
187 INT65292 Binding of ABL2 2 0.36 0 0.39
188 INT168697 Binding of Nedd4 1 0.26 0.48 0.38
189 INT73100 Negative_regulation of PADI4 3 0.57 3.42 0.37
190 INT82806 Negative_regulation of ABL2 3 0.41 0.58 0.37
191 INT171765 Gene_expression of MMP15 3 0.59 7.64 0.36
192 INT33716 Negative_regulation of Positive_regulation of CHRM1 1 0.00 0 0.35
193 INT305619 Negative_regulation of Regulation of MCRS1 1 0.04 1.35 0.35
194 INT229632 Binding of PADI4 21 0.48 37.45 0.34
195 INT73854 Transcription of ABL1 4 0.52 2.26 0.34
196 INT85646 Transcription of PLAT 2 0.67 1.2 0.34
197 INT268386 Positive_regulation of ARAF 6 0.17 4.84 0.33
198 INT202982 Transcription of MCRS1 1 0.25 1.19 0.33
199 INT25048 Negative_regulation of Regulation of PLOD1 2 0.32 0.15 0.32
200 INT45394 Positive_regulation of Localization of CHRM1 1 0.27 0 0.32
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