GO:0006468

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Name protein phosphorylation
Categary Process
Go Slim No
Go Link GO:0006468
Unique Molecular Interactions 10611
Total Molecular Interactions 14002
Total Single Events 114074
Pain Genes Associated 472

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for protein phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36
3 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
4 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
5 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
6 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
7 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
8 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
9 INT140015 Avp Positive_regulation of Localization of Penk 3 0.63 3.48 6.63
10 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
11 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
12 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
13 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
14 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
15 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
16 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
17 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
18 INT44716 Binding of ABL2 and PDYN 2 0.40 0.66 4.77
19 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
20 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
21 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
22 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
23 INT38217 Penk Regulation of Localization of Avp 2 0.38 0.56 4.45
24 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
25 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
26 INT161109 Avp Positive_regulation of Chkb 1 0.12 0.18 4.19
27 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
28 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
29 INT32911 Binding of Insrr and Rbm39 2 0.00 0 3.95
30 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
31 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
32 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9
33 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
34 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
35 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
36 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
37 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76
38 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
39 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
40 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
41 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
42 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
43 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61
44 INT132228 Negative_regulation of Binding of Pik3cg and Sh2d6 1 0.07 1.96 3.6
45 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
46 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
47 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
48 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
49 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
50 INT73071 Binding of Cpe and Insrr 3 0.01 0.33 3.38
51 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
52 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
53 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
54 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
55 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
56 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29
57 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
58 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
59 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
60 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
61 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
62 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
63 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
64 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
65 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
66 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
67 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
68 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08
69 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
70 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
71 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
72 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
73 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
74 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
75 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
76 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
77 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
78 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
79 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
80 INT140014 Avp Negative_regulation of Chkb 1 0.04 1.58 2.86
81 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85
82 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
83 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
84 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
85 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
86 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
87 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
88 INT226118 Ghrl Regulation of Prkag1 1 0.08 0.72 2.72
89 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
90 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
91 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67
92 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67
93 INT7888 Oprl1 Regulation of Localization of Avp 4 0.49 0.25 2.63
94 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
95 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
96 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
97 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
98 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
99 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58
100 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
101 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
102 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
103 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
104 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
105 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
106 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
107 INT107165 Binding of Gabrg1 and Trpv1 2 0.01 0.16 2.34
108 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
109 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
110 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
111 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
112 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
113 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
114 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
115 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
116 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
117 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
118 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
119 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
120 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
121 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
122 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18
123 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
124 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
125 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 0.15 2.85 2.13
126 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13
127 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
128 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
129 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
130 INT63919 Binding of Cck and Insrr 1 0.01 0 2.08
131 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
132 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
133 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
134 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
135 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
136 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
137 INT167530 Phax Regulation of Gene_expression of Trpv1 1 0.16 0.86 2.05
138 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
139 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
140 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
141 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
142 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
143 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
144 INT138960 Dbi Positive_regulation of Avp 1 0.02 1.53 2
145 INT138958 Dbi Positive_regulation of Positive_regulation of Avp 1 0.02 1.53 2
146 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
147 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
148 INT45423 Avp Positive_regulation of Localization of Prl 4 0.67 1.37 1.98
149 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
150 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
151 INT73072 Negative_regulation of Binding of Cpe and Insrr 1 0.00 0 1.94
152 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
153 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
154 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92
155 INT149470 Oxt Regulation of Gene_expression of Avp 1 0.46 1.2 1.92
156 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
157 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
158 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
159 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
160 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
161 INT161079 Mcs18 Negative_regulation of Trpv1 1 0.40 0.82 1.9
162 INT169570 Binding of ROS1 and TRPV1 3 0.33 3.07 1.89
163 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
164 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
165 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88
166 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
167 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
168 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
169 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
170 INT349588 Aap Positive_regulation of Gene_expression of Ros1 1 0.06 0.73 1.85
171 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
172 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
173 INT40239 Penk Regulation of Avp 1 0.07 0 1.84
174 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
175 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
176 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82
177 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
178 INT99138 Coq10a Regulation of Insrr 1 0.01 0.73 1.81
179 INT117269 Binding of Avp and Prl 1 0.25 0.47 1.8
180 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
181 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
182 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
183 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
184 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75
185 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
186 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
187 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
188 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
189 INT157524 Binding of GRM5 and OPRM1 1 0.36 0 1.74
190 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
191 INT182565 Ptger2 Regulation of Trpv1 1 0.25 1.34 1.73
192 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
193 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
194 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
195 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71
196 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
197 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
198 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
199 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
200 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in protein phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59
4 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
5 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
6 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42
7 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42
8 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
9 INT2649 Regulation of Calca 433 0.62 146.05 330.95
10 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
11 INT477 Localization of Avp 813 0.81 131.58 300.4
12 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59
13 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
14 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
15 INT626 Localization of CALCA 289 0.81 125.39 221.15
16 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
17 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
18 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
19 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
20 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
21 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69
22 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
23 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7
24 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
25 INT2541 Binding of Calca 200 0.48 67.14 134.62
26 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4
27 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
28 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
29 INT5008 Localization of Calca 204 0.81 80.35 125.16
30 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75
31 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
32 INT4207 Regulation of Avp 267 0.62 63.72 115.33
33 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
34 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
35 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
36 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83
37 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03
38 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2
39 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
40 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16
41 INT65500 Gene_expression of App 605 0.78 429.94 98.31
42 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
43 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
44 INT214 Localization of AVP 370 0.81 208.51 91.09
45 INT38731 Localization of Trpv1 138 0.81 52.73 90.49
46 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9
47 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
48 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
49 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
50 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
51 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
52 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
53 INT4830 Binding of Trpv1 158 0.48 45.11 84.2
54 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
55 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5
56 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
57 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58
58 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7
59 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68
60 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23
61 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
62 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99
63 INT4153 Binding of Insrr 109 0.40 17.99 72.15
64 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77
65 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
66 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
67 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15
68 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
69 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72
70 INT96622 Localization of Trpv1 110 0.81 59.82 63.25
71 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
72 INT6761 Binding of CALCA 100 0.48 26.71 62.05
73 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
74 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
75 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
76 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
77 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
78 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98
79 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
80 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
81 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
82 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94
83 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
84 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
85 INT119528 Positive_regulation of Camk2a 135 0.70 26.13 54.7
86 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
87 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
88 INT4891 Transcription of Calca 81 0.72 35.27 53.75
89 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
90 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
91 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
92 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
93 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17
94 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
95 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
96 INT12471 Regulation of Insrr 52 0.35 17.8 48.31
97 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
98 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49
99 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41
100 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
101 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
102 INT98498 Binding of Trpv1 75 0.48 33.67 44.4
103 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
104 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38
105 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
106 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
107 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
108 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95
109 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56
110 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
111 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
112 INT685 Regulation of AVP 124 0.62 34.9 39.91
113 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
114 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
115 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02
116 INT115649 Gene_expression of Camk2a 95 0.78 33.22 38
117 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92
118 INT80075 Regulation of Gene_expression of Trpv1 55 0.62 32.42 36.88
119 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
120 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49
121 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
122 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23
123 INT76531 Transcription of Trpv1 62 0.72 23.69 34.77
124 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
125 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67
126 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
127 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28
128 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08
129 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
130 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05
131 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81
132 INT95789 Positive_regulation of Grm5 42 0.55 20.1 33.72
133 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
134 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
135 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
136 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
137 INT114729 Phosphorylation of Camk2a 110 0.82 15.49 33.19
138 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
139 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9
140 INT65698 Localization of CCL2 118 0.81 77.54 32.69
141 INT89055 Phosphorylation of Prkaca 60 0.61 13.41 32.49
142 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
143 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
144 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
145 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
146 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
147 INT8691 Localization of Insr 85 0.80 9.27 30.32
148 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27
149 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25
150 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08
151 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06
152 INT894 Binding of Avp 84 0.48 29.16 29.63
153 INT5300 Regulation of Insr 54 0.60 11.33 29.26
154 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
155 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
156 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
157 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43
158 INT22499 Regulation of Calca 42 0.62 17.32 28.02
159 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96
160 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
161 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
162 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45
163 INT123035 Gene_expression of Ephb1 38 0.78 28.84 27.32
164 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21
165 INT51602 Gene_expression of Grm5 59 0.75 17.29 26.99
166 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
167 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64
168 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
169 INT112036 Phosphorylation of Trpv1 51 0.82 18.59 25.6
170 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
171 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
172 INT103320 Positive_regulation of Positive_regulation of Trpv1 44 0.70 27.73 25.28
173 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27
174 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
175 INT92105 Transcription of Trpv1 47 0.71 27.47 25.01
176 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71
177 INT96904 Regulation of Prkaca 33 0.44 10.86 24.51
178 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
179 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
180 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91
181 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
182 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88
183 INT123386 Negative_regulation of Camk2a 48 0.58 12.57 23.78
184 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
185 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28
186 INT125190 Regulation of Gene_expression of Trpv1 38 0.62 32.57 23.2
187 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
188 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16
189 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
190 INT87607 Positive_regulation of Prkcc 25 0.69 6.06 22.78
191 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67
192 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
193 INT78571 Positive_regulation of Grm5 35 0.69 11.81 22.45
194 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
195 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24
196 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
197 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
198 INT89056 Phosphorylation of Trpv1 46 0.82 13.52 22.16
199 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
200 INT121872 Gene_expression of Camk4 156 0.78 70.47 21.39
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