GO:0006470

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Name protein dephosphorylation
Categary Process
Go Slim No
Go Link GO:0006470
Unique Molecular Interactions 703
Total Molecular Interactions 901
Total Single Events 7001
Pain Genes Associated 56

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein dephosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for protein dephosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125407 Binding of OPRL1 and PTPRM 1 0.03 0.72 4.67
2 INT162992 Binding of Ephb1 and Ppm1e 1 0.03 0.25 1.77
3 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
4 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
5 INT100816 PPP1R14C Regulation of Ppp1cc 1 0.08 0 1.27
6 INT196812 Ppp1r1b Negative_regulation of Ppp1cc 3 0.07 0.13 1.12
7 INT109374 Ppp1cc Negative_regulation of Ppp2r1a 1 0.24 0 1.11
8 INT37153 Binding of Mpz and Ptpn2 1 0.12 0.68 1.08
9 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03
10 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
11 INT348175 Binding of NIDDM1 and PTPN22 1 0.01 2.36 0.99
12 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
13 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 0.21 0.98 0.95
14 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94
15 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
16 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 0.03 1.09 0.92
17 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
18 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.09 0.91
19 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
20 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
21 INT265566 Binding of PDE4D and PTPN5 1 0.03 0.81 0.85
22 INT340115 Comt Regulation of Localization of Dusp1 1 0.12 0.83 0.83
23 INT116558 Ptpn5 Positive_regulation of Nfkb1 1 0.46 2.01 0.83
24 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
25 INT73462 PTPLA Regulation of Gene_expression of SART1 1 0.00 0.79 0.82
26 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
27 INT162995 Positive_regulation of Binding of Ephb1 and Ppm1e 1 0.04 0.06 0.74
28 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
29 INT72229 Binding of NFKBIL1 and BTRC 1 0.00 0 0.73
30 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
31 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
32 INT340116 Dusp1 Regulation of Transcription of Oprm1 1 0.12 0.71 0.69
33 INT232620 Ptpn4 Regulation of Cysltr1 1 0.02 0.58 0.68
34 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
35 INT299282 PTPN3 Negative_regulation of Positive_regulation of RPTOR 1 0.07 0.48 0.67
36 INT274871 Positive_regulation of Cbr2 Positive_regulation of Positive_regulation of Dusp6 1 0.02 0.72 0.67
37 INT74729 Binding of Mpz and Ptprj 1 0.06 0.15 0.66
38 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
39 INT100806 Ppp1r14a Regulation of Ppp1cc 1 0.05 0 0.65
40 INT253935 Binding of PTPLA and Trpv1 1 0.14 1.25 0.65
41 INT169293 PTPLA Positive_regulation of AKT1 1 0.10 0.15 0.64
42 INT329961 Binding of IL2RA and PTPN22 1 0.35 1.87 0.63
43 INT169285 PTPLA Positive_regulation of GRAP2 1 0.03 0.15 0.63
44 INT253137 Ptpn1 Negative_regulation of Ins1 1 0.19 4.11 0.63
45 INT169296 PTPLA Positive_regulation of MAPK3 1 0.10 0.15 0.63
46 INT169295 PTPLA Positive_regulation of MAPK8 1 0.10 0.15 0.63
47 INT218837 Ppp1cc Regulation of Ltp 1 0.13 1.19 0.62
48 INT218835 Ppp1cc Regulation of Cysltr1 1 0.01 1.19 0.62
49 INT218833 Binding of Ppp1cc and Regulation of Ltp 1 0.13 1.2 0.62
50 INT218836 Binding of Ppp1cc and Regulation of Cysltr1 1 0.01 1.2 0.62
51 INT218845 Ppp1cc Positive_regulation of Positive_regulation of Cysltr1 1 0.02 0.92 0.6
52 INT221246 Prkca Negative_regulation of Ptpn2 1 0.04 0.54 0.6
53 INT227499 Binding of PTPN4 and ECA1 1 0.01 0.33 0.59
54 INT169291 CNR1 Positive_regulation of Gene_expression of PTPLA 1 0.19 0.11 0.59
55 INT352463 Gse1 Regulation of Gene_expression of Dusp1 1 0.07 0 0.59
56 INT169298 TRPV1 Positive_regulation of Gene_expression of PTPLA 1 0.20 0.11 0.59
57 INT169292 Positive_regulation of CNR1 Positive_regulation of Gene_expression of PTPLA 1 0.19 0.11 0.59
58 INT162991 Binding of Fadd and Ppm1e 1 0.03 0.09 0.52
59 INT196809 Arpp21 Regulation of Ppp1cc 1 0.01 0 0.52
60 INT196826 Ppp1r1b Regulation of Ppp1cc 1 0.10 0 0.51
61 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
62 INT72230 Binding of BTRC and EMID1 1 0.00 0 0.49
63 INT212806 Rngtt Negative_regulation of Gene_expression of Nos2 1 0.03 0.9 0.49
64 INT72227 Binding of BTRC and AP1M2 1 0.00 0 0.49
65 INT144932 DUSP5 Negative_regulation of TRPV1 1 0.00 0 0.48
66 INT321045 Anpep Positive_regulation of Protein_catabolism of Ptpn6 1 0.01 0.22 0.48
67 INT151485 Negative_regulation of Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
68 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
69 INT151484 Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
70 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
71 INT311557 Binding of ROS1 and Ptpn2 1 0.02 2.32 0.46
72 INT191691 Igh-Dex Positive_regulation of Dusp1 1 0.02 1.8 0.46
73 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
74 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
75 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
76 INT148380 PDP1 Positive_regulation of Positive_regulation of CP 1 0.12 0.64 0.44
77 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 0.00 0.88 0.44
78 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
79 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
80 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
81 INT321047 Anpep Regulation of Negative_regulation of Ptpn6 1 0.01 0.25 0.43
82 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
83 INT210225 Ptpn2 Positive_regulation of Gene_expression of Ifng 1 0.15 1.44 0.42
84 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
85 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
86 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
87 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
88 INT33380 Binding of PTPLA and NPL 1 0.23 0.27 0.41
89 INT313455 Binding of Ppp2ca and Syp 1 0.45 0.68 0.4
90 INT196828 Prkaca Positive_regulation of Ppp2ca 1 0.20 0 0.4
91 INT196800 Trh Negative_regulation of Ppp1cc 1 0.01 0 0.39
92 INT196829 Ppp1r1b Negative_regulation of Phosphorylation of Ppp1cc 1 0.07 0 0.39
93 INT188427 IL6 Positive_regulation of Pdxp 1 0.00 0.84 0.38
94 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
95 INT129768 Binding of LYZ and PTPRC 1 0.34 0.87 0.37
96 INT336573 Ptpn2 Regulation of INSR 1 0.00 1.36 0.36
97 INT218843 Binding of Ppp1cc and Ppp1r9a 1 0.17 0.52 0.36
98 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
99 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
100 INT71925 Binding of Ptprs and Positive_regulation of Racgap1 1 0.10 0 0.35
101 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
102 INT71924 Ptprs Positive_regulation of Racgap1 1 0.10 0 0.35
103 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
104 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
105 INT328043 Binding of PTPRC and Enox2 1 0.00 0.88 0.34
106 INT328044 Positive_regulation of Binding of PTPRC and Enox2 1 0.00 0.89 0.34
107 INT328045 Binding of PTPRC and Tag 1 0.00 0.88 0.34
108 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
109 INT352445 Gse1 Positive_regulation of Gene_expression of Dusp1 1 0.06 0.41 0.34
110 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
111 INT119262 PPM1E Negative_regulation of Positive_regulation of CDKN1A 1 0.01 0.96 0.33
112 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
113 INT253147 Positive_regulation of Nr1h2 Negative_regulation of Positive_regulation of Ptpn1 1 0.17 0.61 0.33
114 INT227496 PTPN4 Regulation of PMEL 1 0.00 0.45 0.33
115 INT274872 Positive_regulation of Cbr2 Positive_regulation of Dusp6 1 0.02 0.63 0.32
116 INT264504 Binding of CRYGD and PTPN22 1 0.04 0.42 0.31
117 INT235869 Binding of Slc6a4 and Ppp2ca 1 0.04 0.21 0.31
118 INT235872 Phosphorylation of Ppp2ca Positive_regulation of Slc37a4 1 0.00 0.15 0.31
119 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
120 INT218831 Ppp1cc Regulation of Gria2 1 0.27 0.86 0.3
121 INT235886 Ppp2ca Positive_regulation of Slc37a4 1 0.00 0.15 0.3
122 INT196825 Prkaca Positive_regulation of Phosphorylation of Ppp2ca 1 0.20 0 0.29
123 INT196831 Positive_regulation of Prkaca Positive_regulation of Ppp2ca 1 0.20 0 0.29
124 INT196814 Negative_regulation of Prkaca Positive_regulation of Ppp2ca 1 0.17 0 0.29
125 INT106893 Ptpn2 Positive_regulation of Tac1 1 0.02 2.02 0.29
126 INT218847 Ppp1cc Positive_regulation of Regulation of Ltp 1 0.22 0.46 0.29
127 INT218936 Dusp1 Negative_regulation of Ephb1 2 0.03 0.89 0.28
128 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
129 INT259936 CTLA4 Regulation of PTPN22 1 0.45 1.64 0.28
130 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
131 INT352458 Dusp1 Regulation of Gene_expression of Tnc 1 0.07 0 0.28
132 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
133 INT352443 Gse1 Regulation of Dusp1 1 0.03 0 0.27
134 INT352449 Dusp1 Regulation of Gene_expression of Slc1a3 1 0.05 0 0.27
135 INT352466 Calca Regulation of Gene_expression of Dusp1 1 0.04 0 0.27
136 INT116561 Ptpn5 Positive_regulation of Nfkb1 1 0.04 0.66 0.27
137 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
138 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
139 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
140 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
141 INT222986 PTPRC Positive_regulation of SMN1 1 0.01 0.46 0.26
142 INT313446 Syp Regulation of Ppp2ca 1 0.58 0.62 0.26
143 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
144 INT222975 PTPRC Positive_regulation of VIM 1 0.05 0.46 0.26
145 INT259937 Binding of CSK and PTPN22 1 0.21 1.69 0.25
146 INT250536 Ghrh Positive_regulation of Negative_regulation of Ptpn6 1 0.09 0 0.24
147 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
148 INT72231 Negative_regulation of Binding of NFKBIL1 and BTRC 1 0.00 0 0.24
149 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
150 INT165637 Ptpn6 Negative_regulation of Positive_regulation of Nfkb1 1 0.02 0.57 0.23
151 INT90280 Binding of Ppp1cc and Ppp2ca 1 0.34 0.22 0.22
152 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
153 INT106761 Tlr4 Positive_regulation of Dusp1 1 0.01 0.16 0.21
154 INT71923 Ptprs Regulation of Racgap1 1 0.09 0 0.21
155 INT165636 Ptpn6 Regulation of Nfkb1 1 0.01 0.36 0.2
156 INT203848 Binding of Pten and Lna1 1 0.06 0.4 0.2
157 INT250537 Ptpn6 Negative_regulation of Igf1 1 0.08 0 0.2
158 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
159 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19
160 INT334314 Tlr4 Positive_regulation of Gene_expression of Dusp1 1 0.01 0.37 0.19
161 INT349504 Ptpn2 Negative_regulation of Th 1 0.23 2 0.19
162 INT274832 Dusp6 Positive_regulation of Localization of Tlr4 1 0.00 0 0.19
163 INT289251 Ptpn11 Regulation of Il6 1 0.09 0.86 0.18
164 INT221234 Gja3 Regulation of Binding of Ptpn2 1 0.08 0.58 0.18
165 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
166 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
167 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
168 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
169 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
170 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
171 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
172 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
173 INT253127 Il6 Regulation of Gene_expression of Ptpn1 1 0.24 1.31 0.17
174 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
175 INT119265 Binding of CREBBP and PPM1E 1 0.01 0.46 0.17
176 INT313449 Siglec1 Regulation of Ppp2ca 1 0.03 0.61 0.17
177 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
178 INT119263 Binding of CDKN1A and PPM1E 1 0.01 0.46 0.17
179 INT119267 Binding of EP300 and PPM1E 1 0.01 0.46 0.17
180 INT96559 Binding of PTPRC and KRT20 2 0.33 1.99 0.16
181 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
182 INT330388 Binding of PTPRC and TLR2 1 0.00 1.19 0.16
183 INT172674 Ptpn6 Negative_regulation of Gene_expression of Plat 1 0.02 1.3 0.16
184 INT349505 Ptpn2 Negative_regulation of Slc6a3 1 0.19 0.7 0.16
185 INT349503 Ptpn2 Negative_regulation of Gene_expression of Th 1 0.23 0.7 0.16
186 INT235883 Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
187 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
188 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
189 INT208264 Park7 Negative_regulation of Pten 1 0.16 1.16 0.15
190 INT235879 Regulation of Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
191 INT253154 TNF Positive_regulation of Ptpn1 1 0.73 0.91 0.15
192 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
193 INT244052 Ppp1ca Regulation of Phosphorylation of Gabrg1 1 0.00 0.18 0.14
194 INT273238 Grin1 Positive_regulation of Ptprs 1 0.07 0.51 0.14
195 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
196 INT244051 Ppp1ca Regulation of Prkaca 1 0.00 0.18 0.14
197 INT222783 Binding of MR1 and PTPRC 1 0.00 0.46 0.14
198 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
199 INT86551 Ppm1f Positive_regulation of Camk1g 1 0.49 0 0.13
200 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein dephosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in protein dephosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
3 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
4 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
5 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
6 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
7 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
8 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57
9 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
10 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
11 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
12 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
13 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
14 INT18736 Gene_expression of Ptpn6 19 0.59 4.44 8.06
15 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
16 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
17 INT43901 Negative_regulation of Ptpn2 65 0.37 56.32 7.48
18 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
19 INT161107 Gene_expression of Ptpn2 58 0.58 49.92 7.4
20 INT9491 Positive_regulation of Ptpn6 11 0.51 2.33 7.32
21 INT106757 Gene_expression of Dusp1 9 0.66 10.45 7.26
22 INT90275 Negative_regulation of Ppp1cc 29 0.58 1.91 7.11
23 INT76120 Gene_expression of Ptprc 102 0.59 30.42 7.02
24 INT32107 Gene_expression of PTPLA 14 0.47 8.06 6.76
25 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
26 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
27 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
28 INT50975 Localization of Ptpn6 8 0.65 2.64 5.7
29 INT106756 Positive_regulation of Gene_expression of Dusp1 7 0.59 7.65 5.24
30 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
31 INT111100 Gene_expression of Dusp1 18 0.76 14.81 5.21
32 INT245593 Gene_expression of PTPN3 32 0.38 10.68 5.09
33 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
34 INT196782 Positive_regulation of Ppp2ca 32 0.61 1.89 4.33
35 INT254145 Gene_expression of Ppap2a 9 0.10 2.66 4.33
36 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
37 INT43903 Regulation of Ptpn2 21 0.41 15.51 4.08
38 INT90277 Negative_regulation of Ppp2ca 15 0.41 4.04 4.02
39 INT276198 Positive_regulation of Pten 1 0.52 5.02 3.88
40 INT17879 Positive_regulation of Ppap2a 17 0.53 9.72 3.8
41 INT11261 Positive_regulation of PTPLA 3 0.50 4.4 3.74
42 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
43 INT90823 Positive_regulation of Ptpn2 25 0.59 22.97 3.59
44 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54
45 INT15930 Positive_regulation of Ptprs 8 0.67 7.02 3.48
46 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45
47 INT6339 Negative_regulation of Ptpn6 6 0.14 0.71 3.44
48 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
49 INT167647 Binding of PTPN5 2 0.32 3.21 3.38
50 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36
51 INT106760 Positive_regulation of Dusp1 16 0.59 8.5 3.35
52 INT37601 Negative_regulation of Ptprs 8 0.42 3.7 3.29
53 INT196779 Phosphorylation of Ppp2ca 28 0.72 1.86 3.25
54 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
55 INT111099 Positive_regulation of Dusp1 11 0.68 7.62 3.18
56 INT64 Regulation of Ptpn6 12 0.14 2.45 3.17
57 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
58 INT192676 Binding of PTEN 14 0.46 10.58 3.06
59 INT202606 Regulation of PTPN5 1 0.26 3.92 3.04
60 INT105884 Binding of Bcl2 19 0.35 15.67 3
61 INT212100 Binding of PTPN4 7 0.32 1.37 2.93
62 INT54749 Binding of BTRC 7 0.09 0.88 2.9
63 INT90276 Gene_expression of Ppp1cc 10 0.73 0.83 2.87
64 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8
65 INT246978 Binding of PTPLA 3 0.18 3.62 2.79
66 INT119383 Gene_expression of Pten 11 0.59 10.33 2.73
67 INT321018 Protein_catabolism of Ptpn6 1 0.14 0.52 2.73
68 INT90273 Positive_regulation of Ppp1cc 10 0.41 0.82 2.71
69 INT98457 Phosphorylation of Ppp1cc 11 0.33 0.12 2.57
70 INT187454 Binding of Ptprc 34 0.38 9.66 2.54
71 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
72 INT230758 Positive_regulation of Gene_expression of PTPRC 11 0.49 6.04 2.45
73 INT111098 Regulation of Dusp1 5 0.27 3.03 2.45
74 INT231573 Binding of PTPN22 5 0.44 7.94 2.33
75 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
76 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
77 INT100805 Binding of Ppp1cc 7 0.47 1.77 2.23
78 INT179885 Regulation of PTEN 8 0.26 11.88 2.18
79 INT137629 Binding of Ptpn6 10 0.30 0.42 2.15
80 INT49433 Binding of PTPRM 2 0.02 0.26 2.15
81 INT321023 Positive_regulation of Localization of Ptpn6 1 0.07 0.27 2.15
82 INT258166 Phosphorylation of Ppap2a 1 0.10 0.97 2.1
83 INT224615 Negative_regulation of Gene_expression of Pten 7 0.59 2.99 2.09
84 INT90272 Gene_expression of Ppp2ca 18 0.68 4.69 2.08
85 INT268616 Positive_regulation of Gene_expression of Ptpn2 7 0.43 8.14 2.08
86 INT276201 Phosphorylation of Pten 1 0.61 1.31 2.08
87 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
88 INT317880 Regulation of Gene_expression of Dusp1 2 0.42 2.98 1.94
89 INT53500 Negative_regulation of Ppap2a 11 0.45 3.31 1.92
90 INT258162 Positive_regulation of Gene_expression of Ppap2a 3 0.09 1.4 1.88
91 INT49432 Gene_expression of PTPRM 2 0.04 0.27 1.87
92 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
93 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
94 INT202602 Positive_regulation of PTPN5 4 0.29 3.34 1.83
95 INT15556 Positive_regulation of Epm2a 3 0.44 1.53 1.69
96 INT38266 Localization of PTPRC 30 0.68 17.05 1.68
97 INT207100 Gene_expression of Ptpn1 13 0.73 8.13 1.68
98 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
99 INT276171 Positive_regulation of Gene_expression of Pten 3 0.52 7.24 1.64
100 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
101 INT206528 Negative_regulation of Gene_expression of Ptprc 8 0.34 3.91 1.61
102 INT22329 Gene_expression of Ptprc 36 0.66 15.84 1.59
103 INT54750 Gene_expression of BTRC 4 0.14 0.99 1.55
104 INT151169 Positive_regulation of Gene_expression of Pten 15 0.45 12.88 1.53
105 INT274884 Positive_regulation of Dusp6 1 0.07 2.08 1.52
106 INT207092 Localization of Dusp1 6 0.70 4.7 1.51
107 INT29856 Negative_regulation of Positive_regulation of Ptpn6 3 0.38 1.24 1.47
108 INT265567 Localization of PTPN5 1 0.49 1.39 1.47
109 INT128478 Positive_regulation of Ptprc 26 0.44 8.1 1.45
110 INT228249 Binding of Pten 7 0.48 3.26 1.45
111 INT281470 Regulation of Gene_expression of Pten 4 0.39 1.13 1.42
112 INT276196 Positive_regulation of Phosphorylation of Pten 1 0.38 0.19 1.41
113 INT178898 Gene_expression of PTPN5 4 0.38 3.06 1.4
114 INT304045 Transcription of PTEN 2 0.51 4.12 1.4
115 INT274892 Gene_expression of Dusp6 1 0.08 1.81 1.4
116 INT212102 Gene_expression of PTPN4 16 0.58 0.2 1.39
117 INT144805 Regulation of Negative_regulation of Ppp2ca 1 0.28 0.24 1.38
118 INT276181 Negative_regulation of Gene_expression of Pten 1 0.44 2.48 1.37
119 INT164817 Negative_regulation of Regulation of Ptpn2 1 0.01 0 1.29
120 INT316787 Binding of Ptpn22 1 0.29 3.61 1.29
121 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
122 INT90771 Positive_regulation of Ptprc 20 0.48 8.43 1.27
123 INT74254 Binding of PTPRC 16 0.36 8.37 1.27
124 INT37253 Negative_regulation of PTPRC 12 0.37 6.13 1.26
125 INT245598 Positive_regulation of PTPN3 3 0.34 1.13 1.23
126 INT206515 Regulation of Gene_expression of Ptprc 6 0.39 3.4 1.22
127 INT212101 Regulation of PTPN4 2 0.25 0.19 1.22
128 INT190014 Regulation of Pten 8 0.62 6.03 1.2
129 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19
130 INT196785 Regulation of Ppp2ca 5 0.54 2.1 1.17
131 INT221190 Phosphorylation of Ptpn2 9 0.48 7 1.15
132 INT314388 Positive_regulation of Gene_expression of Ptpn6 3 0.11 0.05 1.15
133 INT321016 Regulation of Positive_regulation of Ptpn6 1 0.05 0.05 1.15
134 INT321020 Regulation of Protein_catabolism of Ptpn6 1 0.06 0.05 1.12
135 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
136 INT70021 Localization of BCL2 23 0.74 21.6 1.09
137 INT62237 Gene_expression of Ptprf 2 0.65 1.63 1.08
138 INT236138 Negative_regulation of Ptpn1 10 0.55 5.83 1.04
139 INT254146 Localization of Ppap2a 2 0.11 0.39 1.01
140 INT125960 Gene_expression of Ptprs 8 0.78 2.87 0.99
141 INT147464 Binding of Ptprc 13 0.36 15.18 0.98
142 INT253114 Positive_regulation of Ptpn1 9 0.44 5.48 0.96
143 INT90278 Localization of Ppp2ca 4 0.66 1.12 0.94
144 INT43902 Binding of Ptpn2 6 0.29 3.59 0.93
145 INT274888 Negative_regulation of Dusp6 1 0.06 1.82 0.93
146 INT196754 Binding of Ppp2ca 5 0.37 0.42 0.89
147 INT294150 Regulation of Gene_expression of PTPRC 6 0.32 3.3 0.88
148 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
149 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
150 INT221210 Negative_regulation of Gene_expression of Ptpn2 9 0.37 8.3 0.84
151 INT276177 Regulation of Gene_expression of Pten 1 0.34 1.51 0.84
152 INT42766 Localization of Dusp1 1 0.10 0 0.84
153 INT68447 Positive_regulation of PDP1 11 0.64 5.69 0.83
154 INT349490 Positive_regulation of Positive_regulation of Ptpn2 1 0.39 2.33 0.8
155 INT70019 Binding of BCL2 25 0.47 17.55 0.79
156 INT245596 Positive_regulation of Gene_expression of PTPN3 5 0.25 0.92 0.79
157 INT221218 Regulation of Negative_regulation of Ptpn2 3 0.30 2.69 0.79
158 INT253103 Negative_regulation of Gene_expression of Ptpn1 1 0.55 2.56 0.79
159 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
160 INT196741 Positive_regulation of Negative_regulation of Ppp1cc 3 0.33 0.42 0.76
161 INT119834 Phosphorylation of PTEN 12 0.79 6.78 0.75
162 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
163 INT258161 Negative_regulation of Negative_regulation of Ppap2a 1 0.05 0.35 0.75
164 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
165 INT162987 Positive_regulation of Ppm1e 1 0.03 0.06 0.74
166 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
167 INT42722 Negative_regulation of Ptpn11 1 0.21 0 0.71
168 INT196753 Negative_regulation of Phosphorylation of Ppp2ca 3 0.37 0.52 0.7
169 INT253934 Positive_regulation of Binding of PTPLA 1 0.16 0.51 0.69
170 INT196742 Positive_regulation of Positive_regulation of Ppp2ca 4 0.44 0.05 0.68
171 INT226221 Binding of Dusp1 1 0.04 0.92 0.68
172 INT276199 Binding of Pten 2 0.30 0.4 0.67
173 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63
174 INT196739 Regulation of Ppp1cc 5 0.19 0 0.63
175 INT209225 Regulation of Ptprs 3 0.12 1.84 0.63
176 INT321017 Negative_regulation of Protein_catabolism of Ptpn6 1 0.08 0.19 0.63
177 INT274881 Regulation of Dusp6 1 0.04 0.9 0.63
178 INT276179 Regulation of Pten 1 0.46 0.81 0.63
179 INT296253 Negative_regulation of Gene_expression of Ppp2ca 3 0.41 1.71 0.62
180 INT6168 Negative_regulation of Regulation of Ptpn6 1 0.15 0 0.62
181 INT60057 Negative_regulation of Localization of Ptpn6 1 0.31 0.39 0.62
182 INT196765 Positive_regulation of Gene_expression of Ppp2ca 4 0.44 1.05 0.6
183 INT100804 Regulation of Gene_expression of Ppp1cc 2 0.18 0 0.6
184 INT274885 Negative_regulation of Gene_expression of Dusp6 1 0.04 0.89 0.6
185 INT221207 Localization of Ptpn2 5 0.74 5.76 0.59
186 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
187 INT109505 Regulation of Ptprc 3 0.32 2.45 0.58
188 INT21087 Negative_regulation of Ppp3ca 2 0.32 0.31 0.58
189 INT161322 Localization of PTEN 9 0.73 5.65 0.57
190 INT169304 Phosphorylation of PTPLA 1 0.23 0.18 0.57
191 INT100803 Regulation of Phosphorylation of Ppp1cc 1 0.10 0 0.57
192 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
193 INT191677 Positive_regulation of Gene_expression of Dusp1 2 0.20 4.93 0.55
194 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
195 INT274880 Negative_regulation of Positive_regulation of Dusp6 1 0.04 0.89 0.52
196 INT162984 Phosphorylation of Ppm1e 1 0.05 0.09 0.52
197 INT144696 Regulation of Transcription of Bcl2 5 0.44 2.96 0.51
198 INT243952 Phosphorylation of Ppp1ca 3 0.11 0.33 0.51
199 INT74724 Regulation of Ptprj 2 0.05 0.35 0.51
200 INT143131 Regulation of Ptprc 4 0.27 2.56 0.5
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