GO:0006536

From wiki-pain
Jump to: navigation, search
Name glutamate metabolic process
Categary Process
Go Slim No
Go Link GO:0006536
Unique Molecular Interactions 82
Total Molecular Interactions 105
Total Single Events 1988
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for glutamate metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for glutamate metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22
2 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
3 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13
4 INT352464 Gse1 Positive_regulation of Gene_expression of Slc1a3 1 0.05 1.55 1.83
5 INT288731 Binding of Got1 and Gpt 1 0.23 1.25 1.61
6 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12
7 INT160412 Tat Positive_regulation of Transcription of Nos2 1 0.37 0.98 0.86
8 INT160413 Tat Positive_regulation of Gene_expression of Cd40lg 1 0.50 0.98 0.86
9 INT160411 Tat Positive_regulation of Il6 1 0.17 0.89 0.8
10 INT49585 Binding of Glul and Selenbp2 1 0.20 0.19 0.76
11 INT31776 Positive_regulation of Gclc Positive_regulation of G6pd 1 0.29 0.19 0.75
12 INT19577 Gabrg1 Negative_regulation of Got1 1 0.04 0.16 0.74
13 INT160414 Hivan1 Positive_regulation of Tat 1 0.15 0.84 0.66
14 INT115764 Binding of Rbm39 and Tat 1 0.00 0 0.66
15 INT50634 Ddc Regulation of Gene_expression of Glul 1 0.02 0 0.65
16 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62
17 INT152766 TAT Positive_regulation of Positive_regulation of MYLK 1 0.44 0.67 0.61
18 INT152765 TAT Regulation of Positive_regulation of MYLK 1 0.40 0.66 0.6
19 INT288729 Positive_regulation of Binding of Got1 and Gpt 1 0.25 0.61 0.49
20 INT90252 Binding of PPBP and TAT 1 0.39 5.55 0.48
21 INT90262 Binding of TAT and Pf4 1 0.03 5.64 0.48
22 INT117890 Positive_regulation of Gfap Regulation of Glul 1 0.51 0.36 0.46
23 INT117887 Glul Regulation of Arc 1 0.02 0.37 0.46
24 INT117889 Gfap Regulation of Glul 1 0.30 0.36 0.46
25 INT291384 Cntf Positive_regulation of Slc1a3 1 0.26 0.34 0.45
26 INT148465 Positive_regulation of Ccl4 Positive_regulation of Gclc 1 0.32 0.06 0.38
27 INT148467 Ccl4 Positive_regulation of Gclc 1 0.32 0.05 0.37
28 INT96102 Binding of TAT and Selp 1 0.04 0.7 0.3
29 INT96082 Binding of SELP and TAT 1 0.40 0.69 0.3
30 INT96099 Binding of TAT and F2 1 0.01 0.68 0.29
31 INT352461 Calca Regulation of Gene_expression of Slc1a3 1 0.03 0 0.27
32 INT352451 Gse1 Regulation of Slc1a3 1 0.01 0 0.27
33 INT352455 Gse1 Regulation of Gene_expression of Slc1a3 1 0.04 0 0.27
34 INT352449 Dusp1 Regulation of Gene_expression of Slc1a3 1 0.05 0 0.27
35 INT91449 Gpt Positive_regulation of Got1 1 0.01 3.26 0.26
36 INT308815 Got1 Positive_regulation of Ldha 1 0.09 0.71 0.24
37 INT308818 Got1 Positive_regulation of Tnf 1 0.08 0.71 0.24
38 INT288732 Got1 Positive_regulation of Gene_expression of Gpt 1 0.31 0.52 0.23
39 INT25089 Glul Positive_regulation of Npr1 1 0.00 0 0.2
40 INT101812 Binding of KEAP1 and Positive_regulation of Gene_expression of GCLC 1 0.54 0.1 0.19
41 INT101808 Binding of NFE2L2 and Positive_regulation of Gene_expression of GCLC 1 0.54 0.1 0.19
42 INT20202 Binding of TAT and Fgf12 1 0.01 1.5 0.17
43 INT20203 Positive_regulation of Binding of TAT and Fgf12 1 0.01 1.51 0.17
44 INT139538 Binding of CD34 and KIT 2 0.39 2.73 0.14
45 INT96955 Glul Positive_regulation of Positive_regulation of Ugcg 1 0.07 0.14 0.14
46 INT268733 Slc1a3 Regulation of Binding of Slc1a2 1 0.39 0.23 0.14
47 INT95103 TGFBR2 Positive_regulation of CD34 1 0.11 0.61 0.14
48 INT268735 Slc1a2 Regulation of Binding of Slc1a3 1 0.39 0.23 0.14
49 INT299550 TGFB1 Negative_regulation of Glul 1 0.01 0.34 0.14
50 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
51 INT11632 Binding of SERPINE1 and TAT 1 0.11 0.78 0.13
52 INT3751 Binding of GOT1 and PIK3C2A 1 0.08 0.68 0.12
53 INT277986 Negative_regulation of Epo Positive_regulation of Localization of Cd34 1 0.08 0.77 0.12
54 INT101809 Gene_expression of NFE2L2 Positive_regulation of Gene_expression of GCLC 1 0.75 0 0.12
55 INT3752 Binding of GOT1 and LDHA 1 0.11 0.68 0.12
56 INT101811 NFE2L2 Regulation of Gene_expression of GCLC 1 0.67 0.06 0.12
57 INT25090 Negative_regulation of Glul Positive_regulation of Npr1 1 0.00 0 0.1
58 INT118052 Binding of Pecam1 and Cd34 1 0.22 0.51 0.1
59 INT73585 TAT Positive_regulation of Mb 1 0.15 0.64 0.09
60 INT299953 Binding of CD34 and FTSJ3 1 0.04 1.07 0.09
61 INT101807 Gene_expression of KEAP1 Negative_regulation of Positive_regulation of GCLC 1 0.46 0 0.08
62 INT295260 Positive_regulation of Nfe2l2 Positive_regulation of Gene_expression of Gclm 1 0.26 0.23 0.07
63 INT198079 Ass1 Positive_regulation of Gene_expression of Slc1a3 1 0.01 0 0.07
64 INT89724 RYBP Positive_regulation of Gclc 1 0.01 0.21 0.07
65 INT209615 Binding of KRT20 and Cd34 1 0.00 1.05 0.06
66 INT209611 Binding of Mme and Cd34 1 0.00 1.05 0.06
67 INT118227 Binding of ACTG2 and CD34 1 0.15 1.17 0.06
68 INT209610 Binding of Cd22 and Cd34 1 0.01 1.05 0.06
69 INT279907 Binding of GCLM and IRF8 1 0.22 0.82 0.05
70 INT279902 Binding of GCLM and CARD8 1 0.28 0.82 0.05
71 INT279896 Binding of GCLM and STX6 1 0.24 0.82 0.05
72 INT191699 Binding of TAT and TAR 1 0.03 0.75 0
73 INT308314 Binding of CD34 and Pfpl 1 0.03 0.57 0
74 INT191700 Positive_regulation of Binding of TAT and TAR 1 0.04 0.76 0
75 INT191698 Binding of TAT and SORBS1 1 0.01 1.08 0
76 INT276300 TAT Regulation of Gene_expression of VEGFA 1 0.14 1.58 0
77 INT164736 MIR29A Regulation of Glul 1 0.59 0.06 0
78 INT249850 Binding of Ptprc and Cd34 1 0.13 0.48 0
79 INT347035 Binding of Kit and Cd34 1 0.02 1.38 0
80 INT213744 Binding of Cd34 and Epc1 1 0.12 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for glutamate metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in glutamate metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31
2 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51
3 INT127013 Negative_regulation of Slc1a3 37 0.54 14.16 43.97
4 INT9155 Gene_expression of Glul 60 0.77 17.97 23.95
5 INT2911 Positive_regulation of Glul 36 0.70 11.09 22.07
6 INT135673 Positive_regulation of Slc1a3 23 0.57 5.45 21.45
7 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38
8 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13
9 INT2480 Negative_regulation of Got1 43 0.51 14.47 16.09
10 INT24798 Negative_regulation of Glul 52 0.55 27.25 15.17
11 INT98109 Regulation of Slc1a3 15 0.52 6.87 14.43
12 INT135674 Positive_regulation of Gene_expression of Slc1a3 11 0.62 5.21 13.61
13 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39
14 INT182574 Localization of Slc1a3 10 0.73 5.47 11.44
15 INT3851 Gene_expression of Got1 58 0.65 29.15 10.52
16 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97
17 INT24799 Regulation of Glul 22 0.45 8.3 8
18 INT155680 Gene_expression of Slc1a3 22 0.66 6.76 7.23
19 INT127014 Negative_regulation of Negative_regulation of Slc1a3 6 0.54 2.11 6.98
20 INT4208 Regulation of Got1 23 0.44 6.72 6.62
21 INT50633 Regulation of Gene_expression of Glul 12 0.60 1.64 6.59
22 INT136153 Binding of Slc1a3 7 0.40 2.71 6.01
23 INT135675 Positive_regulation of Negative_regulation of Slc1a3 4 0.45 0.38 5.87
24 INT8866 Positive_regulation of TAT 30 0.67 18.06 5.57
25 INT135672 Negative_regulation of Positive_regulation of Slc1a3 4 0.38 0.33 5.49
26 INT27415 Negative_regulation of Positive_regulation of Got1 15 0.51 10.99 5.14
27 INT38251 Negative_regulation of Gclc 7 0.57 1.37 5.06
28 INT99536 Regulation of Gene_expression of Slc1a3 6 0.60 1.76 5.04
29 INT155681 Negative_regulation of Gene_expression of Slc1a3 5 0.36 2.26 4.86
30 INT25146 Negative_regulation of Positive_regulation of Glul 5 0.43 0.91 4.53
31 INT50631 Positive_regulation of Gene_expression of Glul 9 0.43 3 4.37
32 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14
33 INT50646 Transcription of Glul 12 0.38 3.59 4.07
34 INT14717 Gene_expression of TAT 20 0.75 10.67 3.66
35 INT50648 Negative_regulation of Gene_expression of Glul 9 0.58 2.7 3.53
36 INT66570 Localization of Glul 4 0.78 0.37 3.45
37 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28
38 INT3919 Localization of Got1 10 0.71 2.95 3.28
39 INT187803 Negative_regulation of Localization of Slc1a3 1 0.23 1.24 3.2
40 INT31340 Positive_regulation of Gene_expression of Got1 20 0.46 10.5 3.17
41 INT7909 Positive_regulation of Positive_regulation of Got1 8 0.49 6.44 3.06
42 INT155685 Regulation of Gene_expression of Slc1a3 2 0.50 0.77 2.85
43 INT45971 Negative_regulation of GOT1 9 0.51 6.2 2.84
44 INT54331 Positive_regulation of Glul 8 0.67 3.55 2.74
45 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53
46 INT56918 Negative_regulation of TAT 11 0.57 5.92 2.44
47 INT100886 Gene_expression of GCLC 16 0.76 5.63 2.29
48 INT195110 Positive_regulation of Gene_expression of Slc1a3 5 0.44 2.88 2.27
49 INT100897 Positive_regulation of Gene_expression of GCLC 9 0.68 1.84 1.99
50 INT127053 Transcription of Slc1a3 4 0.43 0.8 1.9
51 INT49584 Negative_regulation of Glul 3 0.52 1.16 1.88
52 INT259220 Binding of Glul 3 0.36 0.61 1.78
53 INT56201 Negative_regulation of Negative_regulation of Glul 2 0.31 0.97 1.69
54 INT151270 Positive_regulation of Positive_regulation of Slc1a3 1 0.57 0 1.69
55 INT198066 Negative_regulation of Slc1a3 2 0.41 1.25 1.68
56 INT41395 Positive_regulation of Gclc 9 0.61 1.34 1.66
57 INT50645 Positive_regulation of Positive_regulation of Glul 2 0.21 0.42 1.66
58 INT138294 Regulation of Negative_regulation of Slc1a3 1 0.29 0.17 1.62
59 INT53451 Regulation of TAT 6 0.44 3.07 1.61
60 INT155829 Negative_regulation of Protein_catabolism of Slc1a3 1 0.34 0.1 1.6
61 INT155828 Protein_catabolism of Slc1a3 1 0.80 0.1 1.6
62 INT161371 Gene_expression of Glul 7 0.61 2.44 1.58
63 INT21682 Binding of CD34 18 0.47 13.19 1.47
64 INT259222 Positive_regulation of Binding of Glul 1 0.05 0 1.39
65 INT36330 Positive_regulation of Positive_regulation of GOT1 4 0.32 4.42 1.26
66 INT50649 Positive_regulation of Transcription of Glul 1 0.19 1.28 1.26
67 INT187801 Negative_regulation of Binding of Slc1a3 1 0.26 0.25 1.26
68 INT32120 Binding of Got1 3 0.29 1.98 1.16
69 INT100892 Positive_regulation of GCLC 8 0.68 3.44 1.08
70 INT187804 Positive_regulation of Localization of Slc1a3 1 0.26 0.84 1.06
71 INT3529 Regulation of GOT1 6 0.52 2.4 1.01
72 INT119168 Negative_regulation of Cd34 8 0.37 4.91 0.96
73 INT127051 Positive_regulation of Transcription of Slc1a3 2 0.14 0.37 0.89
74 INT126967 Localization of Cd34 9 0.79 3.69 0.87
75 INT191831 Positive_regulation of Slc1a3 6 0.49 3.66 0.87
76 INT11198 Negative_regulation of Gclc 3 0.59 0.49 0.87
77 INT94194 Transcription of Gclc 1 0.58 0.53 0.87
78 INT96678 Binding of TAT 3 0.47 6.75 0.85
79 INT31775 Positive_regulation of Gclc 3 0.38 0.52 0.84
80 INT96188 Binding of Cd34 11 0.31 10.4 0.82
81 INT12190 Negative_regulation of Localization of Got1 2 0.21 0.98 0.8
82 INT12099 Localization of GOT1 2 0.35 2.54 0.72
83 INT132497 Negative_regulation of Negative_regulation of Got1 1 0.20 0 0.71
84 INT61226 Binding of Gclc 1 0.14 0 0.67
85 INT41394 Regulation of Gclc 5 0.43 1.78 0.64
86 INT94713 Regulation of CD34 11 0.45 8.02 0.58
87 INT128472 Negative_regulation of CD34 7 0.42 3.92 0.58
88 INT167680 Localization of Tat 1 0.73 0.84 0.58
89 INT51485 Localization of TAT 3 0.78 2.18 0.55
90 INT23239 Positive_regulation of Regulation of Got1 2 0.10 0.27 0.54
91 INT60570 Regulation of Gclm 2 0.26 1.3 0.54
92 INT11867 Positive_regulation of Positive_regulation of TAT 2 0.49 2.02 0.54
93 INT163114 Positive_regulation of Gene_expression of GOT1 7 0.24 8.93 0.5
94 INT196003 Regulation of Cd34 4 0.30 3.38 0.5
95 INT73540 Regulation of Positive_regulation of Glul 1 0.30 0.71 0.48
96 INT87819 Localization of CD34 21 0.81 7.69 0.47
97 INT50647 Negative_regulation of Transcription of Glul 1 0.18 0.48 0.47
98 INT147960 Negative_regulation of GCLC 8 0.28 4.4 0.45
99 INT119251 Positive_regulation of Gene_expression of CD34 12 0.49 5.2 0.44
100 INT141799 Transcription of Got1 2 0.35 1.41 0.43
101 INT47387 Negative_regulation of Positive_regulation of GOT1 2 0.26 1.04 0.43
102 INT141796 Negative_regulation of Transcription of Got1 1 0.22 0.43 0.43
103 INT48272 Negative_regulation of Protein_catabolism of Got1 1 0.15 0 0.39
104 INT231341 Negative_regulation of Gene_expression of Got1 2 0.12 1.21 0.38
105 INT198078 Positive_regulation of Negative_regulation of Slc1a3 1 0.40 0.15 0.38
106 INT48271 Protein_catabolism of Got1 1 0.31 0 0.38
107 INT67950 Regulation of Transcription of Glul 1 0.23 0 0.38
108 INT150431 Regulation of Transcription of Slc1a3 1 0.10 0.33 0.37
109 INT198071 Regulation of Slc1a3 1 0.36 0.08 0.35
110 INT232153 Regulation of Negative_regulation of Cd34 1 0.05 0.07 0.35
111 INT55801 Regulation of Positive_regulation of Got1 3 0.08 2.08 0.33
112 INT314001 Regulation of Regulation of Glul 1 0.22 0.54 0.3
113 INT96952 Gene_expression of Gclc 7 0.38 2.08 0.28
114 INT32119 Positive_regulation of Binding of Got1 1 0.13 0.89 0.28
115 INT54169 Regulation of Negative_regulation of Glul 1 0.09 0 0.27
116 INT232504 Negative_regulation of Gene_expression of CD34 4 0.38 1.89 0.23
117 INT101822 Negative_regulation of Positive_regulation of GCLC 1 0.57 0.07 0.23
118 INT55802 Regulation of Gene_expression of Got1 2 0.14 1.23 0.22
119 INT334589 Positive_regulation of Negative_regulation of Got1 1 0.08 1.15 0.21
120 INT55871 Binding of GOT1 1 0.04 2.22 0.19
121 INT195077 Negative_regulation of Positive_regulation of Glul 1 0.19 1.06 0.18
122 INT96951 Positive_regulation of Gene_expression of Gclc 5 0.34 1.45 0.16
123 INT135706 Negative_regulation of Binding of CD34 1 0.40 1.19 0.16
124 INT137457 Positive_regulation of Localization of Cd34 1 0.46 0.55 0.16
125 INT322764 Regulation of GCLM 2 0.27 0.85 0.15
126 INT101819 Positive_regulation of Positive_regulation of GCLC 2 0.59 1.47 0.15
127 INT159088 Gene_expression of Tat 1 0.75 1.43 0.15
128 INT232508 Regulation of Gene_expression of CD34 4 0.43 2.73 0.13
129 INT261021 Positive_regulation of Gene_expression of Gclm 4 0.67 1.45 0.13
130 INT197565 Gene_expression of GCLM 3 0.25 1.47 0.13
131 INT154678 Positive_regulation of Gene_expression of TAT 2 0.49 1.7 0.12
132 INT342900 Negative_regulation of Regulation of GOT1 1 0.04 0.42 0.12
133 INT328416 Protein_catabolism of Glul 1 0.76 0.11 0.12
134 INT351822 Transcription of GCLM 1 0.27 0.66 0.1
135 INT351827 Negative_regulation of Gene_expression of GCLM 1 0.16 0.69 0.08
136 INT261007 Gene_expression of Gclm 7 0.75 4.25 0.06
137 INT261026 Localization of Gclc 3 0.36 0.88 0.06
138 INT261017 Regulation of Gclc 2 0.22 0.88 0.06
139 INT164777 Negative_regulation of Gclm 1 0.21 0.51 0.06
140 INT198065 Binding of Slc1a3 3 0.30 0 0.05
141 INT308300 Positive_regulation of Localization of CD34 3 0.44 1.82 0.05
142 INT229654 Positive_regulation of Gene_expression of Cd34 2 0.45 1.19 0.05
143 INT137310 Positive_regulation of GCLM 1 0.49 0.4 0.05
144 INT277525 Transcription of Slc1a3 1 0.59 0.09 0.05
145 INT221855 Regulation of Positive_regulation of CD34 1 0.31 0.83 0.04
146 INT197485 Regulation of Positive_regulation of GOT1 1 0.01 0.44 0.04
147 INT197486 Positive_regulation of Regulation of GOT1 1 0.01 0.44 0.04
148 INT191701 Regulation of Binding of TAT 1 0.26 0.43 0.04
149 INT186262 Transcription of GCLC 3 0.23 1.19 0
150 INT319631 Positive_regulation of Transcription of Gclc 1 0.17 0 0
151 INT261016 Regulation of Positive_regulation of Gclc 1 0.22 0.23 0
152 INT261012 Regulation of Gene_expression of Gclm 1 0.26 0.23 0
153 INT261003 Positive_regulation of Positive_regulation of Gclm 1 0.29 0.23 0
154 INT273143 Negative_regulation of Tat 1 0.01 2.3 0
155 INT261009 Regulation of Positive_regulation of Gclm 1 0.26 0.23 0
156 INT319621 Transcription of Gclc 1 0.20 0 0
157 INT261006 Positive_regulation of Positive_regulation of Gclc 1 0.24 0.23 0
158 INT313321 Negative_regulation of Transcription of GCLC 1 0.15 0 0
159 INT320552 Transcription of CD34 1 0.67 1.23 0
160 INT246068 Regulation of GCLC 1 0.24 0.11 0
161 INT261029 Binding of Gclm 1 0.21 0 0
162 INT261023 Localization of Gclm 1 0.43 0.39 0
163 INT308295 Positive_regulation of Positive_regulation of CD34 1 0.60 0.44 0
164 INT142214 Positive_regulation of Negative_regulation of Glul 1 0.48 0 0
165 INT261005 Regulation of Localization of Gclc 1 0.13 0.39 0
166 INT261027 Binding of Gclc 1 0.18 0 0
167 INT261025 Positive_regulation of Gclm 1 0.29 0.23 0
168 INT261022 Regulation of Gene_expression of Gclc 1 0.22 0.23 0
169 INT294258 Phosphorylation of CD34 1 0.69 0.06 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox