GO:0006559

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Name L-phenylalanine catabolic process
Categary Process
Go Slim No
Go Link GO:0006559
Unique Molecular Interactions 77
Total Molecular Interactions 105
Total Single Events 657
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for L-phenylalanine catabolic process. They are ordered first by their pain relevance and then by number of times they were reported for L-phenylalanine catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT61687 Binding of Pah and Slc3a1 1 0.00 0.11 1.09
2 INT160412 Tat Positive_regulation of Transcription of Nos2 1 0.37 0.98 0.86
3 INT160413 Tat Positive_regulation of Gene_expression of Cd40lg 1 0.50 0.98 0.86
4 INT188318 MCPH1 Positive_regulation of Pah 3 0.02 3 0.85
5 INT160411 Tat Positive_regulation of Il6 1 0.17 0.89 0.8
6 INT45822 Pah Positive_regulation of Localization of Ins1 1 0.01 0.3 0.73
7 INT160414 Hivan1 Positive_regulation of Tat 1 0.15 0.84 0.66
8 INT115764 Binding of Rbm39 and Tat 1 0.00 0 0.66
9 INT152766 TAT Positive_regulation of Positive_regulation of MYLK 1 0.44 0.67 0.61
10 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61
11 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6
12 INT152765 TAT Regulation of Positive_regulation of MYLK 1 0.40 0.66 0.6
13 INT90252 Binding of PPBP and TAT 1 0.39 5.55 0.48
14 INT90262 Binding of TAT and Pf4 1 0.03 5.64 0.48
15 INT43587 Binding of OPRD1 and Pah 1 0.00 0.08 0.43
16 INT34856 Hpd Negative_regulation of Dbh 1 0.00 0 0.39
17 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
18 INT261597 Binding of PAH and COPD 1 0.00 1.08 0.34
19 INT303005 Binding of Ednra and Pah 1 0.06 1.02 0.32
20 INT96102 Binding of TAT and Selp 1 0.04 0.7 0.3
21 INT96082 Binding of SELP and TAT 1 0.40 0.69 0.3
22 INT96099 Binding of TAT and F2 1 0.01 0.68 0.29
23 INT261609 Binding of PAH and Hypt 1 0.00 1.26 0.28
24 INT284142 ERAS Regulation of PAH 1 0.10 0.55 0.2
25 INT192109 PAH Positive_regulation of Binding of COL7A1 1 0.04 1.45 0.2
26 INT284138 ERAS Regulation of Positive_regulation of PAH 1 0.10 0.55 0.2
27 INT160515 Negative_regulation of Sert1 Negative_regulation of Pah 1 0.34 0.84 0.19
28 INT20202 Binding of TAT and Fgf12 1 0.01 1.5 0.17
29 INT20203 Positive_regulation of Binding of TAT and Fgf12 1 0.01 1.51 0.17
30 INT47164 Binding of Asap1 and Pah 1 0.27 0.07 0.17
31 INT303028 Binding of Pah and MCPH1 1 0.02 1.13 0.16
32 INT86216 Hpd Regulation of NPC1 1 0.02 0.93 0.15
33 INT303003 Gene_expression of Ptgis Positive_regulation of Pah 1 0.36 1.67 0.13
34 INT11632 Binding of SERPINE1 and TAT 1 0.11 0.78 0.13
35 INT303007 Binding of Pah and Ptgis 1 0.26 0.99 0.12
36 INT249923 Binding of Pah and Hif1a 1 0.31 1.16 0.12
37 INT200213 PAH Positive_regulation of SDHD 1 0.21 2.43 0.1
38 INT284140 Binding of EDNRB and PAH 1 0.08 0.1 0.1
39 INT249925 Cpox Negative_regulation of Pah 1 0.01 0.18 0.1
40 INT73585 TAT Positive_regulation of Mb 1 0.15 0.64 0.09
41 INT284141 Binding of EDNRA and PAH 1 0.05 0.1 0.09
42 INT249920 Negative_regulation of Binding of Pah and Hif1a 1 0.37 0.76 0.08
43 INT189550 Binding of BMPR2 and PAH 1 0.06 2.68 0.08
44 INT273616 PVR Positive_regulation of Pah 1 0.10 0.86 0.07
45 INT303027 Gene_expression of MCPH1 Positive_regulation of Pah 1 0.02 0.83 0.07
46 INT249922 Binding of Pah and Asph 1 0.06 0.4 0.04
47 INT343719 Nlrp1a Positive_regulation of PAH 1 0.00 1.9 0.04
48 INT303008 Gene_expression of Pah Positive_regulation of Gene_expression of Ptgis 1 0.31 0.78 0.04
49 INT240946 G6pc Positive_regulation of Regulation of Hgd 1 0.22 0.21 0.03
50 INT47870 Hpd Regulation of Hbb 1 0.20 0.06 0.03
51 INT240943 G6pc Regulation of Regulation of Hgd 1 0.12 0.21 0.03
52 INT275843 HPD Positive_regulation of Ncapg2 1 0.01 0.76 0
53 INT191699 Binding of TAT and TAR 1 0.03 0.75 0
54 INT275842 HPD Positive_regulation of Tlr2 1 0.01 0.76 0
55 INT127464 Binding of PAH and Slc6a4 1 0.08 0 0
56 INT313871 Pde5a Positive_regulation of Pah 1 0.49 0.97 0
57 INT191700 Positive_regulation of Binding of TAT and TAR 1 0.04 0.76 0
58 INT191698 Binding of TAT and SORBS1 1 0.01 1.08 0
59 INT276300 TAT Regulation of Gene_expression of VEGFA 1 0.14 1.58 0
60 INT309846 Binding of pad and Pah 1 0.03 0.98 0
61 INT317602 Binding of TNC and PAH 1 0.02 1.74 0
62 INT242340 Binding of COL7A1 and PAH 1 0.00 1.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for L-phenylalanine catabolic process. They are ordered first by their pain relevance and then by number of times they were reported in L-phenylalanine catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22965 Positive_regulation of Pah 42 0.61 41.41 8.84
2 INT18025 Binding of Pah 32 0.45 30.72 7.93
3 INT32783 Gene_expression of Pah 33 0.60 30.55 6.86
4 INT49468 Negative_regulation of Pah 28 0.55 24.95 6.29
5 INT8866 Positive_regulation of TAT 30 0.67 18.06 5.57
6 INT19158 Gene_expression of PAH 35 0.65 35.81 3.88
7 INT14717 Gene_expression of TAT 20 0.75 10.67 3.66
8 INT124569 Transcription of HPD 6 0.15 1.25 3.32
9 INT9110 Binding of PAH 32 0.41 42.1 3.1
10 INT124570 Gene_expression of HPD 14 0.78 6.76 3.07
11 INT42485 Binding of Pah 9 0.35 3.42 3.03
12 INT29651 Regulation of Pah 11 0.37 9.95 2.79
13 INT127458 Positive_regulation of PAH 24 0.58 27.25 2.53
14 INT200217 Localization of PAH 10 0.36 15.51 2.46
15 INT56918 Negative_regulation of TAT 11 0.57 5.92 2.44
16 INT61685 Positive_regulation of Gene_expression of Pah 6 0.43 4.05 1.79
17 INT53451 Regulation of TAT 6 0.44 3.07 1.61
18 INT22966 Negative_regulation of Positive_regulation of Pah 2 0.50 2.03 1.56
19 INT20130 Positive_regulation of Hpd 6 0.35 4.48 1.44
20 INT27212 Regulation of Hpd 5 0.02 2.33 1.35
21 INT42318 Negative_regulation of Hpd 2 0.31 0.57 1.24
22 INT49466 Negative_regulation of Binding of Pah 2 0.37 0.34 1.24
23 INT127459 Negative_regulation of PAH 18 0.56 15.15 1.05
24 INT42319 Gene_expression of Hpd 5 0.44 11.25 0.9
25 INT124571 Regulation of HPD 3 0.07 1.07 0.89
26 INT96678 Binding of TAT 3 0.47 6.75 0.85
27 INT66485 Negative_regulation of Binding of Pah 2 0.35 1.27 0.83
28 INT36978 Localization of Pah 9 0.73 7.43 0.82
29 INT249912 Positive_regulation of Negative_regulation of Pah 2 0.43 2.49 0.64
30 INT167680 Localization of Tat 1 0.73 0.84 0.58
31 INT51485 Localization of TAT 3 0.78 2.18 0.55
32 INT11867 Positive_regulation of Positive_regulation of TAT 2 0.49 2.02 0.54
33 INT42321 Regulation of Gene_expression of Hpd 1 0.20 0.1 0.54
34 INT124572 Regulation of Gene_expression of HPD 2 0.12 1.95 0.51
35 INT127460 Positive_regulation of Gene_expression of PAH 5 0.43 4.3 0.5
36 INT160514 Regulation of Positive_regulation of Pah 1 0.22 1.62 0.45
37 INT303025 Negative_regulation of Negative_regulation of Pah 1 0.28 1.03 0.34
38 INT45730 Transcription of PAH 3 0.68 2.4 0.33
39 INT27213 Regulation of Regulation of Hpd 1 0.02 0.42 0.32
40 INT127462 Regulation of PAH 5 0.39 3.35 0.29
41 INT127463 Negative_regulation of Positive_regulation of PAH 1 0.30 2.3 0.27
42 INT176330 Positive_regulation of HPD 4 0.47 3.18 0.24
43 INT273611 Positive_regulation of Localization of Pah 1 0.40 0.75 0.24
44 INT313869 Gene_expression of Pah 4 0.63 3.1 0.23
45 INT36979 Negative_regulation of Localization of Pah 1 0.39 0.5 0.2
46 INT201196 Negative_regulation of Gene_expression of PAH 2 0.30 3.11 0.19
47 INT213217 Negative_regulation of Binding of PAH 2 0.32 2.03 0.19
48 INT159088 Gene_expression of Tat 1 0.75 1.43 0.15
49 INT230729 Regulation of Gene_expression of Pah 1 0.24 1 0.13
50 INT154678 Positive_regulation of Gene_expression of TAT 2 0.49 1.7 0.12
51 INT230730 Negative_regulation of Gene_expression of Pah 2 0.28 1.54 0.12
52 INT345424 Phosphorylation of PAH 1 0.05 1.55 0.11
53 INT240928 Negative_regulation of Hgd 1 0.28 1.03 0.11
54 INT188304 Positive_regulation of Positive_regulation of Pah 1 0.18 0.75 0.09
55 INT269716 Binding of HPD 3 0.31 1.42 0.08
56 INT313868 Positive_regulation of Pah 2 0.41 0.67 0.08
57 INT313866 Positive_regulation of Positive_regulation of Pah 1 0.41 0.47 0.08
58 INT240916 Positive_regulation of Hgd 1 0.22 0.33 0.08
59 INT213213 Protein_catabolism of PAH 1 0.76 1.5 0.07
60 INT303023 Protein_catabolism of Pah 1 0.43 2.06 0.06
61 INT313865 Positive_regulation of Gene_expression of Pah 2 0.47 0.95 0.05
62 INT210503 Positive_regulation of Negative_regulation of PAH 1 0.03 0.65 0.05
63 INT270748 Regulation of Regulation of Pah 1 0.04 1.61 0.04
64 INT201197 Regulation of Gene_expression of PAH 1 0.32 1.72 0.04
65 INT191701 Regulation of Binding of TAT 1 0.26 0.43 0.04
66 INT342214 Negative_regulation of Transcription of PAH 1 0.03 0.31 0.03
67 INT348797 Negative_regulation of Positive_regulation of Hpd 1 0.03 0.5 0.03
68 INT273143 Negative_regulation of Tat 1 0.01 2.3 0
69 INT294596 Localization of HPD 1 0.74 0.82 0
70 INT348795 Binding of Hpd 1 0.03 1.62 0
71 INT313870 Negative_regulation of Pah 1 0.48 2.33 0
72 INT355025 Positive_regulation of Binding of HPD 1 0.10 0.63 0
73 INT328696 Negative_regulation of Gene_expression of Pah 1 0.16 0 0
74 INT47869 Binding of Hpd 1 0.37 0.05 0
75 INT310408 Negative_regulation of HPD 1 0.37 0.16 0
76 INT310407 Protein_catabolism of HPD 1 0.57 0 0
77 INT240930 Localization of Hgd 1 0.41 0.16 0
78 INT240913 Negative_regulation of Localization of Hgd 1 0.23 0.16 0
79 INT348803 Localization of Hpd 1 0.06 0.31 0
80 INT240933 Regulation of Hgd 1 0.30 0.71 0
81 INT303017 Regulation of Localization of Pah 1 0.29 0.85 0
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