GO:0006564

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Name L-serine biosynthetic process
Categary Process
Go Slim No
Go Link GO:0006564
Unique Molecular Interactions 13
Total Molecular Interactions 13
Total Single Events 207
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for L-serine biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for L-serine biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT105003 Binding of PDYN and SHMT2 1 0.04 0.49 0.26
2 INT288854 Binding of PTGDR and PHGDH 1 0.00 1.04 0.21
3 INT243557 Binding of PSPH and SPECC1 1 0.01 1.19 0.12
4 INT267158 Binding of IRS1 and SHMT2 1 0.02 0.46 0.05
5 INT331274 Binding of PHGDH and KRT28 1 0.26 0.46 0
6 INT281814 Negative_regulation of Akt1 Positive_regulation of Phgdh 1 0.00 1.7 0
7 INT331272 Binding of PHGDH and KRT26 1 0.16 0.46 0
8 INT187940 PHGDH Regulation of Gene_expression of RNU105A 1 0.32 0.94 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for L-serine biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in L-serine biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT100161 Positive_regulation of Phgdh 6 0.49 0.77 3.81
2 INT14319 Localization of SHMT2 3 0.03 1.91 3.61
3 INT3869 Gene_expression of SHMT2 7 0.37 3.6 3.03
4 INT44493 Regulation of SHMT2 3 0.29 0.45 1.55
5 INT43019 Regulation of PHGDH 4 0.26 2.46 1.53
6 INT108273 Gene_expression of Phgdh 7 0.65 2.29 1.48
7 INT146303 Binding of PHGDH 7 0.36 4.7 1.42
8 INT19619 Positive_regulation of SHMT2 6 0.08 1.05 1.35
9 INT31317 Positive_regulation of PHGDH 6 0.49 4.45 1.22
10 INT100162 Regulation of Positive_regulation of Phgdh 1 0.08 0 1.18
11 INT22480 Binding of SHMT2 5 0.19 2.31 1.14
12 INT81418 Positive_regulation of Localization of SHMT2 1 0.02 0.75 1.06
13 INT43018 Negative_regulation of PHGDH 2 0.42 1.86 1.05
14 INT108274 Positive_regulation of Gene_expression of Phgdh 1 0.15 0.38 0.93
15 INT225140 Positive_regulation of Binding of PHGDH 2 0.22 2.73 0.67
16 INT175294 Binding of Phgdh 2 0.06 1.37 0.57
17 INT108275 Positive_regulation of Positive_regulation of Phgdh 1 0.15 0 0.5
18 INT243550 Gene_expression of PSPH 7 0.25 7.49 0.4
19 INT175295 Negative_regulation of Gene_expression of Phgdh 1 0.08 1.04 0.39
20 INT41689 Gene_expression of PHGDH 11 0.75 6.61 0.28
21 INT102828 Protein_catabolism of SHMT2 1 0.02 0 0.26
22 INT184344 Transcription of Phgdh 1 0.67 0.75 0.17
23 INT338108 Regulation of Gene_expression of PSPH 1 0.16 1.2 0.17
24 INT236049 Negative_regulation of SHMT2 1 0.04 0.13 0.17
25 INT243549 Binding of PSPH 1 0.04 1.13 0.08
26 INT236058 Positive_regulation of Negative_regulation of SHMT2 1 0.05 0.06 0.06
27 INT219709 Localization of Phgdh 1 0.73 0.05 0.04
28 INT187954 Localization of PHGDH 1 0.43 0.45 0.03
29 INT243545 Positive_regulation of PSPH 3 0.14 1.05 0
30 INT243546 Regulation of PSPH 2 0.20 0.89 0
31 INT243551 Negative_regulation of PSPH 1 0.04 0.97 0
32 INT243548 Positive_regulation of Gene_expression of PSPH 1 0.04 0.69 0
33 INT243547 Localization of PSPH 1 0.07 0.26 0
34 INT187955 Transcription of PHGDH 1 0.35 0.09 0
35 INT187949 Regulation of Gene_expression of PHGDH 1 0.30 2.03 0
36 INT331292 Positive_regulation of Gene_expression of PHGDH 1 0.49 0.49 0
37 INT289445 Positive_regulation of Positive_regulation of PSPH 1 0.14 0.08 0
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