GO:0006583

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Name melanin biosynthetic process from tyrosine
Categary Process
Go Slim No
Go Link GO:0006583
Unique Molecular Interactions 20
Total Molecular Interactions 28
Total Single Events 328
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for melanin biosynthetic process from tyrosine. They are ordered first by their pain relevance and then by number of times they were reported for melanin biosynthetic process from tyrosine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104972 MITF Regulation of Transcription of TYR 1 0.20 0.35 1.45
2 INT102762 Binding of POMC and TYR 1 0.12 0.35 0.69
3 INT31531 Mif-ps1 Regulation of TYR 1 0.11 0 0.49
4 INT35685 TYR Regulation of Oxt 1 0.14 0.32 0.36
5 INT71640 Binding of HLA-A and TYR 1 0.16 0.36 0.27
6 INT86634 POMC Positive_regulation of TYR 2 0.42 0 0.24
7 INT323346 Positive_regulation of Tyrp1 Positive_regulation of Positive_regulation of Gpr35 1 0.11 0.76 0.21
8 INT131603 POMC Regulation of TYR 1 0.52 0 0.13
9 INT268083 Ido1 Negative_regulation of Tyrp1 1 0.22 0 0.13
10 INT154736 TYR Regulation of POMC 1 0.30 0.33 0.12
11 INT55459 Binding of OPRM1 and TYR 1 0.08 0 0.1
12 INT94653 Tyrp1 Positive_regulation of Positive_regulation of Tyr 1 0.39 0 0.08
13 INT268087 Binding of Tyrp1 and Gpr35 1 0.02 0 0.08
14 INT313806 Binding of TYR and YOD1 1 0.01 0.49 0.06
15 INT268085 Tdo2 Regulation of Gene_expression of Tyrp1 1 0.25 0.09 0.04
16 INT268084 Tdo2 Positive_regulation of Tyrp1 1 0.26 0.09 0.04
17 INT313810 Binding of MET and TYR 1 0.02 0 0
18 INT313808 Binding of TYR and SPG16 1 0.01 0 0
19 INT313801 Binding of TYR and TYRP1 1 0.03 0 0
20 INT313800 Binding of HLA-B and TYR 1 0.04 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for melanin biosynthetic process from tyrosine. They are ordered first by their pain relevance and then by number of times they were reported in melanin biosynthetic process from tyrosine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT32648 Gene_expression of Tyrp1 80 0.66 17.9 16.59
2 INT85631 Positive_regulation of Tyrp1 40 0.64 18.73 10.84
3 INT13010 Gene_expression of TYR 38 0.65 14.81 8.84
4 INT5481 Binding of TYR 26 0.47 1.3 7.95
5 INT49025 Positive_regulation of TYR 14 0.69 7.15 5.84
6 INT142501 Transcription of Tyrp1 4 0.18 2.09 3.71
7 INT31528 Regulation of TYR 6 0.44 0.83 3.63
8 INT49020 Negative_regulation of TYR 11 0.58 1.97 2.68
9 INT83073 Negative_regulation of Tyrp1 10 0.23 4.4 2.65
10 INT37341 Regulation of Tyrp1 4 0.29 4.53 2.42
11 INT71780 Phosphorylation of TYR 12 0.34 17.21 1.62
12 INT145177 Positive_regulation of Gene_expression of Tyrp1 5 0.30 3.31 1.46
13 INT62425 Regulation of Gene_expression of Tyrp1 7 0.29 1.44 1.41
14 INT323338 Positive_regulation of Positive_regulation of Tyrp1 2 0.13 1.53 1.4
15 INT162196 Binding of Tyrp1 2 0.31 0.69 1.35
16 INT2293 Localization of TYR 3 0.61 0.16 1.06
17 INT49021 Transcription of TYR 2 0.68 0.58 0.99
18 INT148282 Positive_regulation of Gene_expression of TYR 3 0.56 0.6 0.73
19 INT49023 Regulation of Gene_expression of TYR 1 0.27 0.42 0.28
20 INT49026 Regulation of Positive_regulation of TYR 1 0.27 0.4 0.27
21 INT146028 Negative_regulation of Positive_regulation of TYR 1 0.43 0.69 0.26
22 INT196100 Localization of Tyrp1 3 0.36 0 0.19
23 INT212444 Positive_regulation of Phosphorylation of TYR 4 0.18 4.83 0.12
24 INT323337 Positive_regulation of Negative_regulation of Tyrp1 1 0.15 0.86 0.11
25 INT212446 Negative_regulation of Phosphorylation of TYR 1 0.11 3.4 0.04
26 INT268070 Negative_regulation of Positive_regulation of Tyrp1 1 0.23 0.21 0.03
27 INT283887 Positive_regulation of Binding of TYR 1 0.07 0.06 0
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