GO:0006584

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Name catecholamine metabolic process
Categary Process
Go Slim No
Go Link GO:0006584
Unique Molecular Interactions 90
Total Molecular Interactions 120
Total Single Events 1421
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for catecholamine metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for catecholamine metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT289979 Binding of Helt and Negative_regulation of Maoa 1 0.00 0.17 3.14
2 INT172203 Binding of Comt and Maoa 1 0.31 0.98 1.43
3 INT21858 Maoa Regulation of Gene_expression of Spna1 1 0.12 0.18 1.24
4 INT21859 Maoa Regulation of Spna1 1 0.12 0.18 1.23
5 INT168459 Sult1a1 Negative_regulation of Gene_expression of Arr3 1 0.05 2.98 1.23
6 INT21857 Maoa Regulation of Ap3d1 1 0.12 0.18 1.23
7 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
8 INT261617 SNRNP70 Regulation of Comt 1 0.01 0.4 1.18
9 INT31549 Binding of Dbh and Vip 1 0.32 0 1.08
10 INT349576 Binding of Ugt2b and Sult1a1 1 0.00 0.45 1.03
11 INT31548 Binding of Th and Dbh 1 0.35 0 0.98
12 INT56500 Ide Regulation of Maoa 1 0.21 0 0.89
13 INT94665 Nisch Negative_regulation of Maoa 1 0.07 0 0.83
14 INT245350 Abat Regulation of Dbh 1 0.00 0.37 0.8
15 INT56499 Neurod1 Positive_regulation of Maoa 1 0.47 0 0.8
16 INT168455 Sult1a1 Negative_regulation of Nos2 1 0.08 1.99 0.79
17 INT168457 Sult1a1 Positive_regulation of Cat 1 0.15 1.56 0.78
18 INT287132 Binding of NT5E and Comt 1 0.03 0.11 0.73
19 INT28975 Ins1 Positive_regulation of Positive_regulation of Dbh 1 0.21 0 0.66
20 INT106346 Mtpn Regulation of Chat 1 0.06 0 0.52
21 INT139750 Ubqln1 Regulation of Dbh 1 0.00 0 0.52
22 INT139751 Dbh Regulation of Localization of Prl 1 0.02 0 0.52
23 INT167455 Binding of MSD and Comt 1 0.15 0.28 0.5
24 INT168110 Binding of Cnr1 and Dbh 1 0.04 0.64 0.47
25 INT168111 Dbh Positive_regulation of Cnr1 1 0.05 0.64 0.47
26 INT157451 Binding of Slc6a3 and Dbh 1 0.04 0.48 0.44
27 INT168460 Sult1a1 Negative_regulation of Gene_expression of Ifih1 1 0.02 0.96 0.41
28 INT168463 Sult1a1 Negative_regulation of TNF 1 0.01 1 0.4
29 INT168458 Sult1a1 Negative_regulation of Tnf 1 0.09 1 0.4
30 INT68066 Binding of MAOA and NRL 1 0.34 0 0.39
31 INT34856 Hpd Negative_regulation of Dbh 1 0.00 0 0.39
32 INT168461 Sult1a1 Positive_regulation of Gpx1 1 0.12 0.83 0.39
33 INT168454 Sult1a1 Negative_regulation of Ifih1 1 0.02 0.89 0.39
34 INT311616 Binding of MET and Comt 1 0.01 0.2 0.37
35 INT258762 Binding of Dbh and ADHD1 1 0.08 1.61 0.34
36 INT228446 PMAIP1 Regulation of Transcription of Mtpn 1 0.00 0 0.34
37 INT42354 Dbh Regulation of Localization of Gh1 1 0.07 0 0.28
38 INT287131 Negative_regulation of Binding of NT5E and Comt 1 0.03 0.06 0.23
39 INT248171 Epo Regulation of Sult1a1 1 0.08 0.11 0.21
40 INT250853 Binding of Fgf1 and Mtpn 1 0.00 0.28 0.21
41 INT261628 Binding of CHRNA3 and MAOA 1 0.22 1.61 0.17
42 INT261626 Binding of CHRNA5 and MAOA 1 0.22 1.6 0.17
43 INT194360 SNRPD1 Negative_regulation of Dbh 1 0.00 0 0.14
44 INT193553 Mtpn Positive_regulation of Ephb1 1 0.04 0.34 0.13
45 INT193551 Mtpn Positive_regulation of Gene_expression of Gdnf 1 0.02 0.34 0.13
46 INT193552 Gdnf Positive_regulation of Gene_expression of Mtpn 1 0.02 0.34 0.13
47 INT224040 Mtpn Positive_regulation of P2RY1 1 0.00 0.85 0.12
48 INT287130 Positive_regulation of Binding of NT5E and Comt 1 0.04 0 0.12
49 INT16859 Maob Negative_regulation of Maoa 1 0.36 0 0.11
50 INT354194 Mtpn Negative_regulation of MIR524 1 0.00 0.08 0.11
51 INT38074 Gm2232 Negative_regulation of Maoa 1 0.10 0 0.08
52 INT285383 Cars Regulation of Regulation of Sult1a1 1 0.01 0 0.06
53 INT351983 Mtpn Positive_regulation of Gene_expression of Ifng 1 0.01 0.41 0.05
54 INT172205 Binding of Maoa and ADHD1 1 0.03 0.82 0.05
55 INT351979 Mtpn Positive_regulation of Gene_expression of Tnf 1 0.02 0.41 0.05
56 INT206619 Mtpn Positive_regulation of Igf1 1 0.04 0.17 0.05
57 INT84196 Binding of MAOA and FOXI2 1 0.03 0 0.05
58 INT84197 Binding of MAOA and NISCH 1 0.02 0 0.05
59 INT351981 Mtpn Positive_regulation of Gene_expression of Agt 1 0.04 0.41 0.05
60 INT139004 Mtpn Regulation of NFKB1 1 0.33 0.55 0
61 INT175767 IL1B Regulation of Mtpn 1 0.00 0.06 0
62 INT169056 Nfe2l2 Regulation of SULT1A2 1 0.00 0.17 0
63 INT225001 Binding of Mtpn and Trib3 1 0.00 0.15 0
64 INT122293 Binding of SULT1A1 and SULT1A3 1 0.37 0 0
65 INT347265 Gbp1 Negative_regulation of Maoa 1 0.00 0 0
66 INT154023 Binding of NOVA2 and Comt 1 0.03 0.08 0
67 INT169055 Atf2 Regulation of SULT1A2 1 0.00 0.17 0
68 INT122295 Binding of SULT1E1 and SULT1A1 1 0.36 0 0
69 INT225020 Binding of PDGFB and Mtpn 1 0.01 0.15 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for catecholamine metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in catecholamine metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT115 Negative_regulation of Maoa 65 0.59 16.27 38.66
2 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5
3 INT1166 Negative_regulation of Dbh 56 0.59 12.54 28.26
4 INT3382 Positive_regulation of Dbh 33 0.70 11.64 21.67
5 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39
6 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85
7 INT2960 Regulation of Dbh 32 0.47 10.32 18.94
8 INT4073 Localization of Dbh 28 0.81 6.06 16.37
9 INT2396 Regulation of Maoa 25 0.62 6.04 13.27
10 INT520 Binding of Comt 24 0.48 8.98 12.21
11 INT2415 Binding of MAOA 26 0.47 13.26 11.86
12 INT26795 Gene_expression of Mtpn 44 0.62 27.66 8.62
13 INT47546 Binding of Dbh 11 0.44 5.69 7.84
14 INT270 Regulation of MAOA 17 0.60 2.58 6.84
15 INT50712 Gene_expression of Comt 13 0.68 6.33 6.23
16 INT84965 Gene_expression of MAOA 15 0.75 6.9 6.06
17 INT46886 Positive_regulation of Maoa 12 0.69 5.29 5.9
18 INT2162 Regulation of Comt 13 0.60 2.9 5.18
19 INT2871 Positive_regulation of Comt 9 0.50 2.8 4.78
20 INT16887 Binding of Maoa 10 0.41 2.32 4.49
21 INT2397 Gene_expression of Maoa 12 0.77 11.85 3.88
22 INT50295 Regulation of Mtpn 13 0.26 7.54 3.77
23 INT40034 Localization of Maoa 7 0.80 2.17 3.69
24 INT28376 Regulation of Localization of Dbh 1 0.31 0 2.87
25 INT133144 Localization of Mtpn 18 0.24 7.88 2.77
26 INT61231 Gene_expression of SULT1A1 14 0.75 3.01 2.76
27 INT143841 Positive_regulation of Mtpn 17 0.17 5.46 2.68
28 INT105598 Negative_regulation of Mtpn 15 0.16 11.83 2.65
29 INT2958 Transcription of Dbh 4 0.71 2.57 2.64
30 INT128983 Protein_catabolism of Comt 5 0.87 0.22 2.6
31 INT244283 Negative_regulation of Gene_expression of MAOA 2 0.27 1.7 2.5
32 INT31231 Protein_catabolism of MAOA 7 0.96 2.44 2.4
33 INT28971 Positive_regulation of Gene_expression of Dbh 4 0.47 0.58 2.39
34 INT54969 Binding of Sult1a1 4 0.35 1.4 2.18
35 INT2961 Regulation of Regulation of Dbh 3 0.24 0.95 2.05
36 INT246089 Negative_regulation of Negative_regulation of MAOA 2 0.41 2.42 1.92
37 INT56496 Regulation of Localization of Maoa 1 0.41 0 1.82
38 INT447 Localization of Comt 4 0.75 0.76 1.8
39 INT56498 Negative_regulation of Localization of Maoa 2 0.42 0.26 1.78
40 INT21822 Regulation of SULT1A1 3 0.62 0 1.75
41 INT228445 Transcription of Mtpn 1 0.03 0.35 1.72
42 INT40857 Positive_regulation of MAOA 6 0.49 2.51 1.71
43 INT4074 Negative_regulation of Localization of Dbh 4 0.59 0.61 1.48
44 INT47162 Positive_regulation of Negative_regulation of Maoa 2 0.45 0 1.42
45 INT141233 Negative_regulation of Positive_regulation of Dbh 2 0.42 0.39 1.33
46 INT87157 Regulation of Gene_expression of Mtpn 4 0.49 0.78 1.24
47 INT139261 Positive_regulation of Gene_expression of Mtpn 8 0.05 5.95 1.22
48 INT37171 Negative_regulation of SULT1A1 6 0.55 0.18 1.2
49 INT38650 Positive_regulation of Negative_regulation of Dbh 3 0.50 0 1.16
50 INT65165 Positive_regulation of Negative_regulation of Comt 1 0.03 0 1.15
51 INT42124 Negative_regulation of Negative_regulation of Maoa 1 0.42 0.09 1.13
52 INT28972 Regulation of Gene_expression of Dbh 2 0.42 0.86 1.08
53 INT295326 Gene_expression of Sult1a1 2 0.65 1.29 1.06
54 INT228437 Regulation of Transcription of Mtpn 1 0.03 0.08 1.02
55 INT50812 Regulation of Positive_regulation of Dbh 2 0.45 1.04 1
56 INT30598 Negative_regulation of Transcription of Dbh 1 0.42 0.35 0.91
57 INT28974 Negative_regulation of Negative_regulation of Dbh 1 0.40 0 0.78
58 INT243845 Localization of MAOA 4 0.55 1.52 0.77
59 INT344931 Positive_regulation of Protein_catabolism of Comt 1 0.49 0 0.76
60 INT37113 Positive_regulation of Sult1a1 3 0.44 0.81 0.75
61 INT2959 Regulation of Transcription of Dbh 2 0.45 1.18 0.73
62 INT286671 Negative_regulation of Transcription of Maoa 1 0.42 3.45 0.7
63 INT4072 Positive_regulation of Positive_regulation of Dbh 3 0.50 1.77 0.67
64 INT192086 Positive_regulation of Positive_regulation of Mtpn 4 0.06 0.53 0.59
65 INT267109 Regulation of Binding of MAOA 2 0.18 1.15 0.58
66 INT51532 Negative_regulation of Sult1a1 2 0.50 1.72 0.55
67 INT10604 Gene_expression of SULT1A2 12 0.76 0.72 0.52
68 INT172066 Binding of Mtpn 3 0.02 1.51 0.52
69 INT256860 Negative_regulation of Negative_regulation of Mtpn 2 0.16 1.31 0.5
70 INT37013 Negative_regulation of Sult1a1 3 0.57 0.35 0.48
71 INT3381 Positive_regulation of Regulation of Dbh 2 0.44 0.37 0.47
72 INT327669 Negative_regulation of Binding of Maoa 1 0.31 0.07 0.45
73 INT304568 Regulation of Gene_expression of Maoa 1 0.03 0.24 0.43
74 INT46885 Negative_regulation of Positive_regulation of Maoa 1 0.43 0.23 0.43
75 INT4574 Regulation of Negative_regulation of Maoa 2 0.45 0 0.42
76 INT311554 Transcription of MAOA 2 0.69 1.22 0.42
77 INT264574 Positive_regulation of Negative_regulation of MAOA 1 0.37 0.05 0.41
78 INT333284 Positive_regulation of Gene_expression of Maoa 1 0.08 0.07 0.4
79 INT50711 Regulation of Gene_expression of Comt 2 0.01 0 0.39
80 INT47547 Positive_regulation of Binding of Dbh 1 0.47 0 0.39
81 INT121235 Regulation of Protein_catabolism of MAOA 1 0.60 0.34 0.38
82 INT137602 Positive_regulation of SULT1A2 2 0.05 1.1 0.34
83 INT59842 Protein_catabolism of Maoa 2 0.98 2.49 0.32
84 INT228440 Positive_regulation of Transcription of Mtpn 1 0.03 0 0.32
85 INT56192 Regulation of Sult1a1 3 0.44 0.85 0.31
86 INT88769 Negative_regulation of SULT1A2 1 0.27 0.19 0.29
87 INT287124 Negative_regulation of Protein_catabolism of Comt 1 0.38 0.22 0.29
88 INT234490 Transcription of Maoa 3 0.70 2.34 0.27
89 INT301726 Negative_regulation of Positive_regulation of Sult1a1 1 0.04 0.35 0.27
90 INT295323 Positive_regulation of Localization of Sult1a1 1 0.49 1.3 0.27
91 INT295325 Localization of Sult1a1 1 0.73 1.29 0.27
92 INT287126 Negative_regulation of Negative_regulation of Comt 1 0.37 0.78 0.25
93 INT323010 Regulation of Transcription of MAOA 1 0.60 0.34 0.24
94 INT185514 Negative_regulation of Positive_regulation of Mtpn 2 0.03 0.18 0.23
95 INT206445 Binding of SULT1A1 2 0.30 0.24 0.23
96 INT286677 Regulation of Transcription of Maoa 1 0.44 1.15 0.23
97 INT13931 Protein_catabolism of Dbh 1 0.58 0 0.2
98 INT21821 Localization of SULT1A1 1 0.73 0 0.18
99 INT210951 Positive_regulation of Localization of Mtpn 3 0.02 1.75 0.17
100 INT109870 Binding of SULT1A2 2 0.06 1.6 0.17
101 INT111306 Negative_regulation of Gene_expression of Dbh 1 0.25 0.45 0.17
102 INT225012 Regulation of Localization of Mtpn 2 0.01 0.14 0.13
103 INT37114 Localization of Sult1a1 1 0.55 0 0.13
104 INT326802 Protein_catabolism of SULT1A1 1 0.08 0.38 0.11
105 INT209806 Transcription of Comt 1 0.69 2.12 0.11
106 INT285392 Transcription of SULT1A2 1 0.01 0.06 0.1
107 INT278671 Positive_regulation of Gene_expression of SULT1A2 1 0.05 0.57 0.07
108 INT285350 Regulation of Sult1a1 1 0.01 0 0.06
109 INT104466 Binding of Sult1a1 1 0.17 0.48 0.05
110 INT234487 Positive_regulation of Transcription of Maoa 1 0.16 0.36 0.04
111 INT201779 Phosphorylation of Mtpn 2 0.01 0.91 0
112 INT326807 Positive_regulation of SULT1A1 1 0.06 0.1 0
113 INT278663 Positive_regulation of Positive_regulation of SULT1A2 1 0.03 0.19 0
114 INT286672 Positive_regulation of Regulation of Maoa 1 0.46 0.79 0
115 INT246769 Positive_regulation of Phosphorylation of Mtpn 1 0.01 0 0
116 INT326801 Regulation of Gene_expression of SULT1A1 1 0.03 0.06 0
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