GO:0006606

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Name protein import into nucleus
Categary Process
Go Slim No
Go Link GO:0006606
Unique Molecular Interactions 438
Total Molecular Interactions 607
Total Single Events 3343
Pain Genes Associated 25

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein import into nucleus. They are ordered first by their pain relevance and then by number of times they were reported for protein import into nucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
2 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
3 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
4 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 0.14 0 1.7
5 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
6 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
7 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
8 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
9 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
10 INT74185 Cck Negative_regulation of Drd1a 1 0.30 0.1 1.1
11 INT118859 GNA14 Positive_regulation of STAT3 1 0.01 0.38 1.03
12 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
13 INT137919 Binding of Oprm1 and Stat3 1 0.30 0 0.97
14 INT87854 Binding of Drd1a and Positive_regulation of Localization of Abat 1 0.08 0 0.96
15 INT74184 Cck Regulation of Localization of Drd1a 1 0.32 0.06 0.95
16 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
17 INT136172 NPY Negative_regulation of Positive_regulation of Drd1a 1 0.21 0 0.91
18 INT7292 Binding of Drd1a and Penk 1 0.14 0 0.9
19 INT52760 Oprd1 Regulation of Drd1a 1 0.02 0 0.9
20 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
21 INT104126 STAT3 Regulation of Phospho1 1 0.00 0.06 0.86
22 INT29279 Binding of Drd1a and Htr1a 1 0.35 0.2 0.84
23 INT344101 Positive_regulation of Drd1a Positive_regulation of Localization of Abat 1 0.01 0 0.84
24 INT184116 Il10 Positive_regulation of Stat3 2 0.18 1.15 0.77
25 INT353721 Negative_regulation of Binding of Drd1a and Ghsr 1 0.16 0 0.76
26 INT118854 GNA14 Positive_regulation of Positive_regulation of STAT3 1 0.02 0.31 0.76
27 INT353720 Binding of Drd1a and Ghsr 1 0.18 0 0.76
28 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
29 INT348174 Binding of STAT3 and IL23R 1 0.40 1.9 0.76
30 INT155096 Stat3 Regulation of Mapk3 1 0.36 0.45 0.76
31 INT21260 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.05 0 0.76
32 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74
33 INT99938 Drd1a Regulation of Transcription of Qrfp 1 0.03 0 0.69
34 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68
35 INT99939 Drd1a Regulation of Qrfp 1 0.03 0 0.68
36 INT177979 Binding of STAT3 and FOXI2 1 0.00 1.83 0.61
37 INT317638 Ins1 Positive_regulation of Gene_expression of Drd1a 1 0.14 0.86 0.59
38 INT317634 Ins1 Positive_regulation of Drd1a 1 0.14 0.86 0.59
39 INT350699 Binding of Casp8 and Stat3 1 0.04 1.81 0.58
40 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56
41 INT192971 Positive_regulation of Il6 Positive_regulation of Localization of Stat3 1 0.03 0.86 0.56
42 INT5111 DIO2 Positive_regulation of Drd1a 1 0.04 0 0.53
43 INT143862 Bdnf Positive_regulation of Gene_expression of NUP214 1 0.27 0.61 0.52
44 INT143861 Nfatc1 Regulation of Gene_expression of NUP214 1 0.00 0.61 0.52
45 INT223925 Drd1a Positive_regulation of Gene_expression of Serpina1 1 0.01 0 0.51
46 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51
47 INT121822 Binding of STAT3 and Olr1583 1 0.00 0.21 0.51
48 INT340212 Csf2 Positive_regulation of Pttg1ip 1 0.02 0.46 0.49
49 INT302820 Stat3 Regulation of Positive_regulation of Il7 1 0.04 1.03 0.49
50 INT302823 Stat3 Regulation of Gene_expression of Il7 1 0.04 1.03 0.49
51 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48
52 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
53 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
54 INT290671 Binding of Socs3 and Stat3 2 0.23 1.59 0.45
55 INT167154 FPR1 Positive_regulation of ING1 1 0.18 0.18 0.44
56 INT317635 Positive_regulation of Drd1a Positive_regulation of Phosphorylation of Gtf3a 1 0.01 0.53 0.43
57 INT184138 Ik Positive_regulation of Stat3 1 0.01 0.29 0.43
58 INT184135 Il11ra1 Positive_regulation of Stat3 1 0.20 0.3 0.4
59 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4
60 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
61 INT32244 Slc3a1 Positive_regulation of Localization of Drd1a 1 0.15 0 0.39
62 INT32243 Drd1a Positive_regulation of Localization of Slc3a1 1 0.15 0 0.39
63 INT328818 Regulation of Il6 Positive_regulation of Stat3 1 0.04 0 0.38
64 INT344103 Positive_regulation of Drd1a Positive_regulation of Obfc1 1 0.00 0 0.38
65 INT303982 Il6 Positive_regulation of STAT3 1 0.03 0.41 0.37
66 INT37247 Binding of Drd1a and Drd2 1 0.20 0 0.37
67 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37
68 INT328825 Il6 Positive_regulation of Stat3 1 0.07 0 0.37
69 INT356274 Egf Positive_regulation of Localization of Stat3 1 0.13 0.22 0.36
70 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
71 INT188204 Negative_regulation of IL6 Positive_regulation of STAT3 1 0.28 0.54 0.34
72 INT20468 Ran Negative_regulation of Localization of Prl 1 0.30 0 0.33
73 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
74 INT155064 Stat3 Negative_regulation of Tp53bp2 1 0.06 3.69 0.33
75 INT254217 Tyk2 Positive_regulation of Stat3 1 0.23 0.83 0.33
76 INT254209 Jak1 Positive_regulation of Stat3 1 0.18 0.84 0.33
77 INT155058 Stat3 Negative_regulation of Akp3 1 0.01 3.7 0.33
78 INT299289 AKT1 Positive_regulation of Positive_regulation of TSC2 1 0.17 0 0.3
79 INT118853 Negative_regulation of SRC Negative_regulation of Positive_regulation of STAT3 1 0.41 0.08 0.28
80 INT97595 Penk Regulation of Gene_expression of Drd1a 1 0.25 0.1 0.28
81 INT298348 ANGPT2 Positive_regulation of Phosphorylation of Stat3 1 0.18 0.14 0.28
82 INT276953 Positive_regulation of Tlr2 Positive_regulation of Phosphorylation of Stat3 1 0.38 0.93 0.27
83 INT276979 Positive_regulation of Tlr2 Positive_regulation of Gene_expression of Stat3 1 0.38 0.93 0.27
84 INT118860 MCC Positive_regulation of Phosphorylation of STAT3 1 0.01 0.1 0.27
85 INT315200 Negative_regulation of Binding of Socs3 and Stat3 1 0.26 1.18 0.27
86 INT118856 Positive_regulation of GNA14 Positive_regulation of STAT3 1 0.01 0.14 0.26
87 INT300779 STAT3 Positive_regulation of CRP 1 0.41 0.62 0.26
88 INT300778 STAT3 Positive_regulation of Transcription of CRP 1 0.38 0.62 0.26
89 INT73385 Cfp Regulation of Drd1a 1 0.10 0 0.25
90 INT73384 Positive_regulation of Cfp Regulation of Drd1a 1 0.18 0 0.25
91 INT325312 IL20 Positive_regulation of Phosphorylation of STAT3 1 0.13 0.58 0.24
92 INT325316 IL22 Positive_regulation of Phosphorylation of STAT3 1 0.19 0.58 0.24
93 INT325315 Binding of STAT3 and TH1L 1 0.16 0.6 0.23
94 INT261465 Binding of Drd1a and Ptgdr 1 0.03 0.1 0.23
95 INT118861 OPRD1 Positive_regulation of STAT3 1 0.07 0.07 0.23
96 INT188200 IL6ST Positive_regulation of STAT3 1 0.25 0.38 0.23
97 INT240539 Il12a Positive_regulation of Stat3 1 0.11 0.75 0.22
98 INT337295 PTAFR Positive_regulation of Localization of STAT3 1 0.43 0.85 0.22
99 INT325314 Binding of IL12A and STAT3 1 0.19 0.6 0.22
100 INT237748 Negative_regulation of Jak3 Negative_regulation of Positive_regulation of Stat3 1 0.25 1.01 0.22
101 INT276968 Il6 Positive_regulation of Gene_expression of Stat3 2 0.20 1.54 0.21
102 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
103 INT188201 OSM Positive_regulation of Phosphorylation of STAT3 1 0.40 0.24 0.21
104 INT279964 STAT3 Regulation of Transcription of FGG 1 0.22 1.37 0.2
105 INT275159 Agt Positive_regulation of Phosphorylation of Stat3 1 0.04 1.44 0.2
106 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
107 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
108 INT286965 Binding of STAT3 and FOXP3 1 0.27 1.84 0.19
109 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19
110 INT290672 Stat3 Negative_regulation of Il6 1 0.08 0.4 0.18
111 INT316477 Stat3 Positive_regulation of Il10 1 0.39 0.35 0.18
112 INT155067 Csf2 Positive_regulation of Transcription of Stat3 1 0.36 1.45 0.18
113 INT295268 S100a8 Positive_regulation of Stat3 1 0.00 0.5 0.18
114 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
115 INT107884 Stat3 Positive_regulation of JUN 1 0.08 0 0.17
116 INT155232 TXNIP Regulation of BAX 1 0.23 0.15 0.17
117 INT298641 PPARA Regulation of STAT3 1 0.23 0.98 0.16
118 INT316484 Akt1 Positive_regulation of Positive_regulation of Stat3 1 0.01 0.87 0.16
119 INT129592 St13 Positive_regulation of Protein_catabolism of Stat3 1 0.26 0.84 0.16
120 INT129593 St13 Positive_regulation of Positive_regulation of Stat3 1 0.28 0.84 0.16
121 INT207253 INS Negative_regulation of TXNIP 1 0.45 1.2 0.15
122 INT316490 Il6 Positive_regulation of Positive_regulation of Stat3 1 0.50 0.33 0.15
123 INT161797 Binding of ECE1 and ING1 1 0.01 0.68 0.14
124 INT332254 Pdgfa Positive_regulation of Stat3 1 0.02 0.52 0.14
125 INT161795 Positive_regulation of Binding of ECE1 and ING1 1 0.02 0.68 0.14
126 INT134698 Regulation of Prnp Positive_regulation of Nup214 1 0.26 1.18 0.14
127 INT356285 Binding of Stat3 and Egf 1 0.09 0.4 0.13
128 INT161798 Positive_regulation of Binding of EDN1 and ING1 1 0.06 0.66 0.13
129 INT299553 GOPC Positive_regulation of Stat3 1 0.02 0 0.13
130 INT161800 Binding of EDN1 and ING1 1 0.05 0.65 0.13
131 INT134697 Prnp Positive_regulation of Nup214 1 0.44 1.18 0.13
132 INT320770 Dsg2 Positive_regulation of Stat3 1 0.28 0.74 0.13
133 INT241070 Klf16 Positive_regulation of Drd1a 1 0.05 0.13 0.12
134 INT289253 Il23a Positive_regulation of Stat3 1 0.04 0.37 0.12
135 INT188197 LIF Positive_regulation of STAT3 1 0.35 0.27 0.12
136 INT188198 OSM Positive_regulation of STAT3 1 0.52 0.24 0.12
137 INT207254 ZNF236 Positive_regulation of TXNIP 1 0.03 0.68 0.12
138 INT321826 Stat3 Positive_regulation of Localization of CSF2 1 0.02 0 0.12
139 INT317162 Binding of Bdnf and Htt 1 0.51 0.2 0.12
140 INT182496 AGT Positive_regulation of Phosphorylation of STAT3 1 0.03 0.79 0.12
141 INT273018 Binding of FGF9 and PDE1A 1 0.18 0.3 0.11
142 INT273020 Binding of FGF9 and PDE11A 1 0.22 0.3 0.11
143 INT319315 Binding of Ap2a2 and Htt 1 0.28 0.64 0.11
144 INT275157 Binding of Stat3 and Rac1 1 0.05 0.71 0.1
145 INT286963 EGF Positive_regulation of Gene_expression of STAT3 1 0.03 0.57 0.1
146 INT272006 Binding of YWHAQ and Tsc2 1 0.27 0.39 0.1
147 INT107883 Stat3 Positive_regulation of Gene_expression of JUN 1 0.08 0 0.1
148 INT275158 Rac1 Positive_regulation of Stat3 1 0.07 0.72 0.1
149 INT208298 IGIP Positive_regulation of Stat3 1 0.09 0.48 0.09
150 INT286964 IL23A Positive_regulation of STAT3 1 0.05 0.57 0.09
151 INT206054 RAC1 Positive_regulation of STAT3 1 0.07 0.11 0.09
152 INT298634 Binding of IL6 and STAT3 1 0.04 1.41 0.08
153 INT273373 SOCS3 Regulation of Phosphorylation of STAT3 1 0.42 0.06 0.08
154 INT310564 Positive_regulation of Ephb1 Regulation of Stat3 1 0.03 0.17 0.08
155 INT238215 Binding of STAT3 and Bmx 1 0.12 0.63 0.08
156 INT299539 Lif Positive_regulation of Phosphorylation of Stat3 1 0.08 0 0.08
157 INT273374 Binding of JAK2 and STAT3 1 0.24 0 0.07
158 INT337290 PTAFR Positive_regulation of Phosphorylation of STAT3 1 0.43 0.07 0.07
159 INT273368 Negative_regulation of Binding of JAK2 and STAT3 1 0.28 0 0.07
160 INT107886 Stat3 Positive_regulation of Gene_expression of TRPC6 1 0.38 0 0.07
161 INT188208 EGF Regulation of STAT3 1 0.46 0 0.07
162 INT348021 Stat3 Regulation of Vps54 1 0.02 1.32 0.07
163 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07
164 INT316492 Stat3 Positive_regulation of Socs3 1 0.46 0.19 0.06
165 INT286966 IL2 Positive_regulation of Binding of STAT3 1 0.04 0.5 0.06
166 INT261454 Akr1d1 Regulation of Drd1a 1 0.00 0.71 0.06
167 INT354822 Negative_regulation of Stat3 Negative_regulation of Positive_regulation of IFNA1 1 0.02 0.85 0.06
168 INT336993 Binding of PDIA3 and CALCRL 1 0.00 0 0.06
169 INT212440 STAT3 Regulation of Phosphorylation of SOAT1 1 0.11 1.42 0.05
170 INT238117 Positive_regulation of STAT3 Positive_regulation of Gene_expression of JAK2 1 0.11 0 0.05
171 INT238218 STAT3 Positive_regulation of Gene_expression of Socs3 1 0.14 0 0.05
172 INT206087 RAC1 Positive_regulation of Gene_expression of STAT3 1 0.08 0.05 0.05
173 INT317181 Binding of Htt and Uts2r 1 0.04 0 0.05
174 INT238116 STAT3 Positive_regulation of Gene_expression of JAK2 1 0.16 0 0.05
175 INT229490 Binding of Vim and Kpna4 1 0.02 0.21 0.04
176 INT316485 Stat3 Positive_regulation of Transcription of Ccnd1 1 0.23 1.27 0.04
177 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04
178 INT246793 Binding of Tsc2 and Tsc1 1 0.04 0.71 0.04
179 INT238211 Binding of STAT3 and Sik1 1 0.04 0.25 0.04
180 INT316489 Stat3 Positive_regulation of Transcription of Ccnb1 1 0.02 1.27 0.04
181 INT316486 Stat3 Positive_regulation of Transcription of Cdc2b 1 0.28 1.27 0.04
182 INT276965 Gbp6 Positive_regulation of Localization of Stat3 1 0.01 0.69 0.04
183 INT286968 Positive_regulation of STAT3 Regulation of Gene_expression of CD4 1 0.16 0.44 0.04
184 INT252897 Binding of PTTG1IP and PTTG1 1 0.04 0.15 0.04
185 INT252892 PTTG1IP Regulation of PTTG1 1 0.05 0.49 0.04
186 INT286967 Positive_regulation of STAT3 Regulation of Gene_expression of FOXP3 1 0.35 0.44 0.04
187 INT276947 Gbp6 Positive_regulation of Phosphorylation of Stat3 1 0.01 0.7 0.04
188 INT282540 STAT3 Positive_regulation of Positive_regulation of MAPK1 1 0.04 0.27 0.04
189 INT246786 Ogg1 Regulation of Phosphorylation of Tsc2 1 0.20 0.42 0.04
190 INT316499 Stat3 Positive_regulation of Transcription of MYC 1 0.55 1.27 0.04
191 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04
192 INT306527 Binding of Htt and Aifm1 1 0.20 0.82 0.04
193 INT289538 Sirt1 Positive_regulation of Stat3 1 0.34 0.37 0.04
194 INT276954 Hspd1 Positive_regulation of Stat3 1 0.31 0.65 0.04
195 INT253017 PTTG1IP Regulation of Regulation of Fgf2 1 0.03 0.49 0.04
196 INT276986 Gbp6 Positive_regulation of Stat3 1 0.01 0.69 0.04
197 INT238113 SRC Regulation of Phosphorylation of STAT3 1 0.46 0 0.04
198 INT205480 Egfr Positive_regulation of Stat3 5 0.58 4.11 0.03
199 INT238212 Binding of STAT3 and Pxn 1 0.02 0 0.03
200 INT206076 IL6 Positive_regulation of Positive_regulation of STAT3 1 0.19 0.3 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein import into nucleus. They are ordered first by their pain relevance and then by number of times they were reported in protein import into nucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5858 Positive_regulation of Drd1a 66 0.69 4.51 51.73
2 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43
3 INT13838 Positive_regulation of Drd1a 48 0.70 9.83 23.42
4 INT7680 Regulation of Drd1a 27 0.45 4.52 18.86
5 INT107454 Positive_regulation of Stat3 43 0.68 19.63 17.69
6 INT51779 Gene_expression of Drd1a 46 0.66 11.18 17.51
7 INT7020 Negative_regulation of Drd1a 25 0.57 1.84 17.1
8 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95
9 INT5859 Positive_regulation of Positive_regulation of Drd1a 20 0.55 2.05 15.61
10 INT129584 Positive_regulation of Stat3 97 0.68 87.07 14.86
11 INT107875 Phosphorylation of Stat3 49 0.80 13.18 12.66
12 INT7682 Binding of Drd1a 22 0.48 1.8 11.83
13 INT114874 Gene_expression of Stat3 78 0.76 53.99 9.49
14 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42
15 INT16735 Localization of Drd1a 11 0.61 0.35 8.42
16 INT114873 Phosphorylation of Stat3 63 0.82 30.19 8.23
17 INT22369 Negative_regulation of Drd1a 15 0.47 6.13 6.87
18 INT129918 Positive_regulation of Phosphorylation of Stat3 17 0.63 5.42 6.28
19 INT21552 Regulation of Drd1a 10 0.57 3.7 6.05
20 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94
21 INT18366 Negative_regulation of Positive_regulation of Drd1a 6 0.42 0.49 5.54
22 INT101925 Binding of Drd1a 9 0.43 1.82 4.97
23 INT114871 Positive_regulation of Phosphorylation of Stat3 20 0.69 12.34 4.6
24 INT48567 Transcription of Drd1a 7 0.51 2.44 4.54
25 INT113078 Phosphorylation of Drd1a 4 0.30 0.77 4.45
26 INT13333 Regulation of Gene_expression of Drd1a 8 0.36 3.37 4.28
27 INT91371 Negative_regulation of STAT3 34 0.59 25 4.08
28 INT97392 Gene_expression of Stat3 27 0.65 14.21 4.06
29 INT340193 Positive_regulation of Pttg1ip 1 0.53 12.8 3.91
30 INT121818 Binding of STAT3 25 0.47 11.16 3.67
31 INT62901 Positive_regulation of Gene_expression of Drd1a 2 0.57 0.66 3.35
32 INT13335 Negative_regulation of Gene_expression of Drd1a 6 0.34 0.8 3.16
33 INT158630 Positive_regulation of Positive_regulation of Stat3 16 0.49 14.75 3.08
34 INT18365 Positive_regulation of Regulation of Drd1a 4 0.50 1.74 3.04
35 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
36 INT97393 Localization of Stat3 11 0.75 7.33 3.01
37 INT114878 Positive_regulation of Gene_expression of Stat3 15 0.49 10.81 2.91
38 INT113077 Positive_regulation of Phosphorylation of Drd1a 1 0.11 0.15 2.87
39 INT340189 Gene_expression of Pttg1ip 1 0.52 5.16 2.83
40 INT340186 Negative_regulation of Pttg1ip 1 0.33 1.78 2.65
41 INT64248 Positive_regulation of Positive_regulation of Drd1a 6 0.45 1.97 2.62
42 INT89929 Positive_regulation of Positive_regulation of STAT3 22 0.65 9.21 2.54
43 INT89992 Positive_regulation of Gene_expression of Drd1a 5 0.39 2.11 2.54
44 INT129917 Negative_regulation of Phosphorylation of Stat3 6 0.41 0.85 2.51
45 INT140993 Negative_regulation of Positive_regulation of Stat3 6 0.38 3.39 2.39
46 INT86462 Transcription of Drd1a 3 0.44 1.86 2.36
47 INT178193 Negative_regulation of Stat3 25 0.58 17.82 2.27
48 INT115193 Positive_regulation of Phosphorylation of STAT3 30 0.64 11.37 2.2
49 INT24407 Negative_regulation of Binding of Drd1a 3 0.25 0.81 2.18
50 INT21046 Regulation of Positive_regulation of Drd1a 3 0.44 0.09 2.06
51 INT155234 Gene_expression of TXNIP 48 0.77 24.4 2.05
52 INT140268 Negative_regulation of Positive_regulation of Stat3 9 0.47 7.59 2.05
53 INT140991 Negative_regulation of Stat3 15 0.53 7.55 2.04
54 INT13837 Negative_regulation of Positive_regulation of Drd1a 2 0.43 1.43 2.01
55 INT101243 Regulation of STAT3 12 0.62 9.98 1.92
56 INT165617 Localization of STAT3 28 0.78 9.04 1.72
57 INT192965 Localization of Stat3 15 0.74 7.05 1.68
58 INT140305 Negative_regulation of Binding of Drd1a 2 0.21 0.54 1.46
59 INT113079 Regulation of Phosphorylation of Drd1a 1 0.06 0.07 1.43
60 INT167162 Phosphorylation of ING1 1 0.64 0.52 1.41
61 INT121207 Negative_regulation of Phosphorylation of Stat3 16 0.45 9.35 1.4
62 INT340195 Regulation of Pttg1ip 1 0.47 4.53 1.4
63 INT97394 Regulation of Stat3 6 0.41 2.52 1.34
64 INT228036 Negative_regulation of Cfl1 1 0.09 1.1 1.34
65 INT77809 Gene_expression of NUP214 3 0.65 1.35 1.24
66 INT136470 Positive_regulation of Positive_regulation of Stat3 3 0.40 0.75 1.23
67 INT91368 Negative_regulation of Phosphorylation of STAT3 14 0.59 9.22 1.2
68 INT206136 Positive_regulation of Gene_expression of STAT3 14 0.46 4.3 1.1
69 INT108997 Localization of Htt 28 0.77 3.76 1.07
70 INT142068 Positive_regulation of Localization of Stat3 3 0.47 1.6 1.07
71 INT184839 Localization of Drd1a 4 0.73 0.84 1.03
72 INT167160 Positive_regulation of Phosphorylation of ING1 1 0.39 0.38 1.01
73 INT155053 Transcription of Stat3 6 0.50 3.97 1
74 INT101240 Regulation of Phosphorylation of STAT3 5 0.57 3.04 0.98
75 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
76 INT64690 Negative_regulation of Localization of Drd1a 2 0.09 0 0.95
77 INT74183 Positive_regulation of Localization of Drd1a 1 0.32 0.06 0.95
78 INT99668 Positive_regulation of Binding of Drd1a 2 0.43 0.89 0.87
79 INT340196 Negative_regulation of Positive_regulation of Pttg1ip 1 0.33 1.32 0.84
80 INT154886 Gene_expression of Htt 18 0.76 15.51 0.82
81 INT340211 Negative_regulation of Gene_expression of Pttg1ip 1 0.33 0.97 0.82
82 INT242559 Gene_expression of Kpnb1 6 0.07 9.27 0.81
83 INT167164 Negative_regulation of Phosphorylation of ING1 1 0.33 0.2 0.77
84 INT178186 Regulation of Stat3 7 0.44 6.23 0.74
85 INT207285 Positive_regulation of Gene_expression of TXNIP 1 0.69 9.53 0.73
86 INT205476 Binding of Stat3 12 0.47 4.73 0.72
87 INT128314 Gene_expression of Cry2 2 0.46 0.18 0.68
88 INT128326 Regulation of Gene_expression of Cry2 1 0.03 0.09 0.68
89 INT252054 Phosphorylation of TSC2 4 0.80 0.63 0.67
90 INT153157 Regulation of Regulation of Drd1a 2 0.25 0.2 0.66
91 INT184848 Positive_regulation of Transcription of Drd1a 1 0.26 0.93 0.65
92 INT228246 Negative_regulation of Gene_expression of Stat3 10 0.58 8.11 0.64
93 INT140306 Regulation of Binding of Drd1a 1 0.20 0.36 0.64
94 INT72516 Regulation of Binding of Drd1a 2 0.44 0.4 0.63
95 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6
96 INT165618 Negative_regulation of Localization of STAT3 2 0.39 0.31 0.59
97 INT21087 Negative_regulation of Ppp3ca 2 0.32 0.31 0.58
98 INT287206 Regulation of Gene_expression of Htt 6 0.50 3.27 0.57
99 INT161804 Positive_regulation of ING1 2 0.39 0.83 0.57
100 INT215340 Localization of Htt 10 0.61 5.12 0.55
101 INT78238 Binding of PDIA3 2 0.36 0.87 0.54
102 INT287204 Protein_catabolism of Htt 6 0.99 2.8 0.53
103 INT91372 Negative_regulation of Positive_regulation of STAT3 8 0.40 2 0.5
104 INT119230 Negative_regulation of Htt 5 0.42 2.99 0.5
105 INT205477 Transcription of Stat3 4 0.68 3.15 0.5
106 INT79311 Positive_regulation of Positive_regulation of PDIA3 1 0.49 0.34 0.47
107 INT77749 Localization of Kpna4 1 0.10 0 0.47
108 INT243418 Binding of Htt 14 0.30 5.94 0.44
109 INT165597 Positive_regulation of Htt 8 0.60 4.27 0.44
110 INT121816 Positive_regulation of Binding of STAT3 3 0.49 0.8 0.4
111 INT101242 Regulation of Gene_expression of STAT3 4 0.62 2.11 0.39
112 INT132864 Binding of Htt 15 0.46 2.34 0.38
113 INT48566 Regulation of Transcription of Drd1a 1 0.32 0 0.37
114 INT287207 Regulation of Protein_catabolism of Htt 3 0.45 1.73 0.35
115 INT119371 Regulation of Positive_regulation of STAT3 2 0.42 0.36 0.35
116 INT207078 Gene_expression of Cfl1 1 0.16 0.85 0.34
117 INT221833 Positive_regulation of TSC2 2 0.23 0.39 0.33
118 INT207066 Localization of Cfl1 1 0.18 0.83 0.33
119 INT155054 Regulation of Gene_expression of Stat3 2 0.50 4.73 0.32
120 INT101241 Positive_regulation of Negative_regulation of STAT3 1 0.70 1.53 0.32
121 INT242561 Positive_regulation of Kpnb1 2 0.05 1.96 0.29
122 INT254877 Positive_regulation of Gene_expression of Htt 15 0.64 6.29 0.28
123 INT179341 Binding of Stat3 3 0.23 0.95 0.27
124 INT276919 Regulation of Phosphorylation of Stat3 3 0.35 1.32 0.27
125 INT289579 Negative_regulation of Gene_expression of Stat3 2 0.28 1.01 0.27
126 INT34275 Positive_regulation of Ppp3ca 2 0.31 0.24 0.27
127 INT76252 Positive_regulation of NUP214 1 0.45 0.17 0.27
128 INT136052 Negative_regulation of Negative_regulation of Drd1a 1 0.13 0.66 0.27
129 INT97779 Negative_regulation of TSC2 3 0.41 3.45 0.26
130 INT246762 Phosphorylation of Tsc2 60 0.67 15.71 0.25
131 INT144038 Transcription of STAT3 4 0.56 0.99 0.25
132 INT79313 Positive_regulation of PDIA3 2 0.49 0.27 0.23
133 INT287205 Regulation of Htt 5 0.45 3.56 0.22
134 INT154360 Localization of Tsc2 1 0.56 0.16 0.22
135 INT1594 Binding of Ppp3ca 1 0.29 0 0.22
136 INT289227 Regulation of Gene_expression of Stat3 4 0.47 3.66 0.21
137 INT64674 Regulation of PTTG1IP 3 0.24 0.48 0.21
138 INT254040 Regulation of FGF9 2 0.57 1.04 0.21
139 INT206166 Negative_regulation of Binding of STAT3 4 0.55 1.13 0.2
140 INT157288 Positive_regulation of Cfl1 2 0.45 1.49 0.19
141 INT64675 Negative_regulation of PTTG1IP 2 0.38 0.16 0.18
142 INT340191 Regulation of Positive_regulation of Pttg1ip 1 0.35 1.95 0.18
143 INT335080 Negative_regulation of Negative_regulation of Stat3 1 0.16 0.46 0.18
144 INT139662 Gene_expression of FGF9 7 0.65 2.26 0.17
145 INT252998 Gene_expression of PTTG1IP 1 0.17 2.06 0.17
146 INT129583 Protein_catabolism of Stat3 1 0.41 0.83 0.16
147 INT276934 Negative_regulation of Localization of Stat3 4 0.45 1.99 0.15
148 INT131584 Gene_expression of PDIA3 2 0.33 0.7 0.15
149 INT158508 Negative_regulation of Gene_expression of STAT3 2 0.43 1.74 0.15
150 INT157287 Positive_regulation of Phosphorylation of Cfl1 1 0.11 0.41 0.15
151 INT157285 Phosphorylation of Cfl1 1 0.18 0.41 0.15
152 INT290661 Regulation of Regulation of Stat3 1 0.29 0.36 0.14
153 INT134696 Regulation of Nup214 1 0.26 1.18 0.14
154 INT134695 Negative_regulation of Nup214 1 0.42 1.28 0.14
155 INT271943 Phosphorylation of Tsc2 9 0.52 3.35 0.13
156 INT206163 Positive_regulation of Localization of STAT3 4 0.29 0.43 0.13
157 INT119228 Gene_expression of TSC2 3 0.75 4.43 0.13
158 INT155235 Negative_regulation of TXNIP 2 0.58 2.44 0.13
159 INT290655 Positive_regulation of Transcription of Stat3 1 0.33 0.41 0.13
160 INT246776 Negative_regulation of Tsc2 18 0.48 6.82 0.12
161 INT246749 Negative_regulation of Phosphorylation of Tsc2 11 0.35 3.4 0.12
162 INT276922 Positive_regulation of Localization of Stat3 1 0.39 1.34 0.12
163 INT340190 Transcription of Pttg1ip 1 0.53 0.34 0.12
164 INT271941 Binding of Tsc2 12 0.24 2.96 0.11
165 INT207291 Negative_regulation of Gene_expression of TXNIP 1 0.58 3.47 0.11
166 INT340192 Regulation of Regulation of Pttg1ip 1 0.35 0.29 0.11
167 INT10452 Positive_regulation of PTTG1IP 2 0.41 0.6 0.1
168 INT249399 Localization of Kpnb1 2 0.63 0.53 0.09
169 INT252971 Positive_regulation of Gene_expression of PTTG1IP 1 0.11 1.37 0.09
170 INT293587 Positive_regulation of Gene_expression of Kpnb1 1 0.04 0.28 0.09
171 INT246772 Regulation of Phosphorylation of Tsc2 1 0.26 1.37 0.09
172 INT262957 Localization of SIX3 1 0.23 0.67 0.09
173 INT63183 Negative_regulation of Kpnb1 2 0.37 8.26 0.08
174 INT332857 Binding of Cry2 2 0.32 0 0.08
175 INT332843 Negative_regulation of Binding of Cry2 1 0.33 0 0.08
176 INT63182 Regulation of Negative_regulation of Kpnb1 1 0.39 0.47 0.08
177 INT287203 Negative_regulation of Gene_expression of Htt 7 0.37 5.08 0.07
178 INT144039 Negative_regulation of Negative_regulation of STAT3 2 0.55 0.85 0.07
179 INT168674 Positive_regulation of Binding of ING1 1 0.10 0.35 0.07
180 INT168673 Binding of ING1 1 0.07 0.35 0.07
181 INT292967 Positive_regulation of Gene_expression of Stat3 4 0.48 1.35 0.06
182 INT248969 Transcription of Cry2 2 0.59 0.56 0.06
183 INT261890 Positive_regulation of Gene_expression of Htt 1 0.43 0.85 0.06
184 INT206143 Positive_regulation of Transcription of STAT3 1 0.21 0.34 0.06
185 INT316449 Negative_regulation of Binding of Stat3 2 0.42 0.4 0.05
186 INT246770 Positive_regulation of Negative_regulation of Tsc2 1 0.20 1.91 0.05
187 INT356269 Negative_regulation of Localization of Stat3 1 0.15 0 0.05
188 INT317175 Positive_regulation of Localization of Htt 1 0.48 0 0.05
189 INT306521 Transcription of Htt 1 0.69 4.13 0.05
190 INT271916 Positive_regulation of Phosphorylation of Tsc2 4 0.32 0.52 0.04
191 INT242338 Binding of TSC2 2 0.22 1.56 0.04
192 INT275740 Regulation of Phosphorylation of Stat3 2 0.18 0.13 0.04
193 INT290790 Phosphorylation of Cry2 1 0.46 0.29 0.04
194 INT290783 Protein_catabolism of Cry2 1 0.48 0.19 0.04
195 INT252994 Binding of PTTG1IP 1 0.09 0.67 0.04
196 INT276940 Regulation of Localization of Stat3 1 0.35 0.74 0.04
197 INT331204 Negative_regulation of Binding of Htt 1 0.04 0.64 0.04
198 INT290799 Positive_regulation of Protein_catabolism of Cry2 1 0.34 0.19 0.04
199 INT261891 Negative_regulation of Gene_expression of Htt 1 0.37 1.12 0.04
200 INT271937 Positive_regulation of Binding of Tsc2 1 0.25 0 0.04
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