GO:0006622

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Name protein targeting to lysosome
Categary Process
Go Slim No
Go Link GO:0006622
Unique Molecular Interactions 21
Total Molecular Interactions 23
Total Single Events 69
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein targeting to lysosome. They are ordered first by their pain relevance and then by number of times they were reported for protein targeting to lysosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT168699 Binding of Nedd4 and Tyr 1 0.02 0.45 0.46
2 INT89469 Fk Positive_regulation of Gene_expression of Lhcgr 1 0.01 0 0.24
3 INT89470 CGA Regulation of Gene_expression of Lhcgr 1 0.00 0 0.23
4 INT89468 Fk Regulation of Gene_expression of Lhcgr 1 0.01 0 0.23
5 INT168700 Positive_regulation of Binding of Nedd4 and Tyr 1 0.03 0.19 0.17
6 INT200326 Hdac1 Negative_regulation of Lhcgr 1 0.03 0 0.12
7 INT200318 Hdac1 Negative_regulation of Transcription of Lhcgr 1 0.03 0 0.12
8 INT200346 Hdac2 Negative_regulation of Lhcgr 1 0.04 0 0.12
9 INT200347 Hdac2 Negative_regulation of Transcription of Lhcgr 1 0.04 0 0.12
10 INT249416 Binding of Scarb2 and Napa 1 0.02 0 0.05
11 INT186185 Binding of SCARB1 and SCARB2 1 0.22 0.58 0.05
12 INT186192 Binding of SCARB2 and TBP 1 0.02 0.58 0.05
13 INT186183 Binding of SCARB2 and SASH3 1 0.00 0.49 0.04
14 INT209159 Binding of LHCGR and PDE5A 1 0.01 0 0
15 INT188836 Binding of LHCGR and C4b 1 0.39 0.76 0
16 INT329013 Binding of LITAF and Nedd4 1 0.15 1.4 0
17 INT329012 Binding of MPZ and Nedd4 1 0.03 0.7 0
18 INT287616 Ap3b1 Regulation of Binding of Fmr1 1 0.01 0 0
19 INT287615 Ap3b1 Regulation of Binding of Fxr1 1 0.00 0 0
20 INT287617 Ap3b1 Regulation of Fxr1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein targeting to lysosome. They are ordered first by their pain relevance and then by number of times they were reported in protein targeting to lysosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT89467 Gene_expression of Lhcgr 9 0.36 1.59 1.62
2 INT54527 Negative_regulation of Ap3b1 3 0.01 1.24 0.89
3 INT38373 Positive_regulation of Ap3b1 4 0.37 1.01 0.86
4 INT145676 Binding of Ap3b1 1 0.02 0.38 0.55
5 INT89465 Positive_regulation of Gene_expression of Lhcgr 4 0.24 1.03 0.41
6 INT168697 Binding of Nedd4 1 0.26 0.48 0.38
7 INT38371 Regulation of Ap3b1 2 0.22 0.58 0.32
8 INT38372 Positive_regulation of Regulation of Ap3b1 1 0.37 0 0.32
9 INT89466 Regulation of Gene_expression of Lhcgr 1 0.29 0 0.25
10 INT168693 Negative_regulation of Binding of Nedd4 1 0.31 0.29 0.21
11 INT168696 Positive_regulation of Binding of Nedd4 1 0.34 0.29 0.21
12 INT186197 Gene_expression of SCARB2 7 0.40 2.93 0.13
13 INT106498 Positive_regulation of Lhcgr 2 0.08 0.41 0.12
14 INT200267 Transcription of Lhcgr 1 0.09 0 0.12
15 INT153274 Gene_expression of LHCGR 2 0.67 1.53 0.1
16 INT186202 Binding of SCARB2 1 0.19 0.58 0.05
17 INT209191 Positive_regulation of LHCGR 1 0.28 0.05 0.05
18 INT186200 Negative_regulation of Gene_expression of SCARB2 2 0.22 1.02 0.04
19 INT186194 Protein_catabolism of SCARB2 1 0.34 0.5 0.04
20 INT186193 Negative_regulation of Protein_catabolism of SCARB2 1 0.22 0.5 0.04
21 INT170543 Gene_expression of Ap3b1 2 0.02 1.45 0
22 INT223183 Positive_regulation of Lhcgr 1 0.09 0.2 0
23 INT318007 Regulation of Lhcgr 1 0.40 0.63 0
24 INT209178 Regulation of Regulation of LHCGR 1 0.25 0 0
25 INT271652 Regulation of Gene_expression of Ap3b1 1 0.01 0.15 0
26 INT209186 Regulation of LHCGR 1 0.35 0 0
27 INT259709 Negative_regulation of SCARB2 1 0.03 1.2 0
28 INT186203 Transcription of SCARB2 1 0.36 0.57 0
29 INT345468 Localization of SCARB2 1 0.73 0 0
30 INT209188 Negative_regulation of Positive_regulation of LHCGR 1 0.24 0 0
31 INT352685 Positive_regulation of Gene_expression of SCARB2 1 0.11 0.51 0
32 INT345466 Positive_regulation of Localization of SCARB2 1 0.49 0 0
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