GO:0006635

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Name fatty acid beta-oxidation
Categary Process
Go Slim No
Go Link GO:0006635
Unique Molecular Interactions 140
Total Molecular Interactions 183
Total Single Events 1685
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for fatty acid beta-oxidation. They are ordered first by their pain relevance and then by number of times they were reported for fatty acid beta-oxidation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
2 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
3 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
4 INT160879 POMC Positive_regulation of DECR1 1 0.04 0.08 1.02
5 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
6 INT11446 BLZF1 Positive_regulation of Positive_regulation of DECR1 1 0.03 0 0.72
7 INT82311 Binding of HADHA and Gast 1 0.03 0.37 0.68
8 INT82312 Negative_regulation of Binding of HADHA and Gast 1 0.04 0.37 0.68
9 INT153797 NUBPL Negative_regulation of PPARD 1 0.02 0.69 0.64
10 INT83424 Binding of CD40LG and ADIPOQ 2 0.13 1 0.59
11 INT83426 ADIPOQ Negative_regulation of Binding of CD40LG 2 0.21 1 0.59
12 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52
13 INT83423 ADIPOQ Negative_regulation of Binding of IGHG3 1 0.02 0.31 0.42
14 INT215290 Siglec1 Negative_regulation of Decr1 1 0.00 0.68 0.41
15 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4
16 INT296945 ADIPOQ Negative_regulation of TNF 1 0.03 1.13 0.4
17 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
18 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
19 INT240616 Binding of SHBG and ADIPOQ 1 0.31 4.43 0.37
20 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
21 INT240626 Binding of ADIPOQ and Hdlcl1 1 0.02 3.27 0.28
22 INT36306 HADH Positive_regulation of NKG7 1 0.07 1.07 0.28
23 INT243802 Binding of co and Decr1 1 0.00 0 0.27
24 INT150514 Decr1 Positive_regulation of Gsr 1 0.13 0.24 0.24
25 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23
26 INT179492 Binding of Ins1 and Adipoq 1 0.16 1.16 0.23
27 INT249760 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Adipoq 1 0.20 0.81 0.22
28 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22
29 INT242996 Adipoq Negative_regulation of Transcription of Cd68 1 0.22 0.6 0.21
30 INT242994 Adipoq Negative_regulation of Spp1 1 0.19 0.59 0.21
31 INT332304 Binding of Il6 and Adipoq 1 0.03 0.4 0.2
32 INT145886 Binding of CXCL1 and Adipoq 1 0.00 0.77 0.2
33 INT352518 Binding of FAT1 and Adipoq 1 0.01 2.79 0.2
34 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19
35 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19
36 INT3488 Binding of CPT2 and CPT1C 1 0.13 0.57 0.19
37 INT298784 PPARA Positive_regulation of CPT1B 1 0.28 1.61 0.19
38 INT334394 ADIPOQ Negative_regulation of Gene_expression of Tnf 1 0.37 1.06 0.18
39 INT207186 Binding of Adipoq and Bmi1 1 0.01 1.65 0.18
40 INT228168 Adipoq Positive_regulation of Prkag1 2 0.05 1.08 0.17
41 INT199105 Decr1 Positive_regulation of Positive_regulation of Nos2 1 0.01 0.23 0.16
42 INT240622 Binding of ADIPOQ and Etv3 1 0.04 1.32 0.15
43 INT157275 Binding of PRKAA1 and Adipoq 1 0.01 1.13 0.15
44 INT189796 Binding of EHHADH and Cd14 1 0.13 0.9 0.14
45 INT301638 Ppara Regulation of Slc27a2 1 0.30 0.29 0.14
46 INT157273 Adipoq Positive_regulation of PRKAA1 1 0.03 1.16 0.14
47 INT127156 HSD17B10 Regulation of Acaa2 1 0.02 0 0.12
48 INT270663 Adipoq Positive_regulation of Il6 1 0.02 1.05 0.12
49 INT179493 Adipoq Positive_regulation of Ins1 1 0.20 0.99 0.12
50 INT270669 Adipoq Positive_regulation of IL8 1 0.01 1.06 0.12
51 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
52 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
53 INT270665 Adipoq Positive_regulation of Ccl2 1 0.07 1.06 0.12
54 INT164746 Binding of LEP and Adipoq 1 0.07 0.69 0.12
55 INT228175 RNU1-1 Regulation of Adipoq 1 0.11 0.78 0.12
56 INT257467 Fat1 Regulation of Gene_expression of Adipoq 1 0.08 0.56 0.11
57 INT240624 Binding of ADIPOQ and Hdl1 1 0.02 0.85 0.1
58 INT168854 Binding of Mb and Fabp3 1 0.03 0.57 0.1
59 INT262996 ADIPOQ Regulation of INS 1 0.13 1.25 0.1
60 INT310275 Negative_regulation of Binding of Adipoq and Ins1 1 0.19 1.14 0.09
61 INT157276 PPARG Positive_regulation of Adipoq 1 0.29 1.09 0.09
62 INT168856 Binding of Tnnt2 and Fabp3 1 0.05 0.57 0.09
63 INT298786 PPARA Positive_regulation of Transcription of CPT1B 1 0.17 0.93 0.09
64 INT157274 Adipoq Positive_regulation of ADIPOR1 1 0.00 1.2 0.09
65 INT310274 Binding of Adipoq and Ins1 1 0.21 1.14 0.09
66 INT42225 Binding of ABCA1 and DECR1 1 0.02 0 0.08
67 INT228174 RNU1-1 Positive_regulation of Gene_expression of Adipoq 1 0.12 0.55 0.08
68 INT257466 Psd Negative_regulation of Gene_expression of Adipoq 1 0.22 0.66 0.08
69 INT267154 ADIPOQ Regulation of Positive_regulation of SUGT1 1 0.03 1.18 0.08
70 INT352517 Binding of INS and Adipoq 1 0.09 1.32 0.07
71 INT262997 Binding of HSD11B1 and ADIPOQ 1 0.54 2.82 0.07
72 INT260392 Hmox1 Positive_regulation of Adipoq 1 0.32 0.65 0.07
73 INT301623 Ins1 Positive_regulation of Slc27a2 1 0.01 0.37 0.07
74 INT336380 Gene_expression of Adipoq Positive_regulation of Ppara 1 0.06 1.77 0.07
75 INT140813 Binding of Retn and Adipoq 1 0.03 1.18 0.06
76 INT267157 LEP Positive_regulation of ADIPOQ 1 0.10 0.51 0.05
77 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05
78 INT228169 Gm2733 Regulation of Adipoq 1 0.00 0.51 0.05
79 INT228591 Adipoq Positive_regulation of Phosphorylation of Prkaa2 1 0.31 0.61 0.04
80 INT236590 Binding of Adipoq and Ncoa2 1 0.15 0.2 0.03
81 INT236587 Binding of Adipoq and Ncoa1 1 0.17 0.2 0.03
82 INT314370 Adipoq Positive_regulation of Tnfrsf11a 1 0.04 1.26 0.03
83 INT236592 Positive_regulation of Binding of Adipoq and Ncoa2 1 0.19 0.2 0.03
84 INT290033 Binding of PPARD and NR1H4 1 0.01 0.39 0
85 INT227305 Zbp1 Regulation of Gene_expression of Adipoq 1 0.21 1.27 0
86 INT204323 Binding of ADIPOQ and Negative_regulation of Gene_expression of ROS1 1 0.08 0.12 0
87 INT352516 Binding of POMT1 and Adipoq 1 0.01 0.4 0
88 INT290025 Binding of INS and PPARD 1 0.03 0.47 0
89 INT204322 Binding of ADIPOQ and Positive_regulation of Gene_expression of PPARGC1A 1 0.30 0.07 0
90 INT260395 Positive_regulation of Adipoq Negative_regulation of Gene_expression of Hmox1 1 0.34 1.4 0
91 INT290030 Binding of PPARD and PPARG 1 0.09 0.38 0
92 INT106438 DECR1 Positive_regulation of Positive_regulation of PHB2 1 0.53 0 0
93 INT140814 Adipoq Regulation of Retn 1 0.03 0.8 0
94 INT227302 Zbp1 Regulation of Transcription of Adipoq 1 0.09 1.27 0
95 INT313502 Binding of ALOX5AP and ADIPOQ 1 0.05 0.44 0
96 INT290023 Binding of PPARD and RXRG 1 0.03 0.39 0
97 INT350254 Slc12a6 Regulation of Gene_expression of Adipoq 1 0.02 0.63 0
98 INT197915 Des Positive_regulation of Adipoq 1 0.07 0 0
99 INT332943 Binding of SNRNP70 and Adipoq 1 0.00 1.35 0
100 INT353062 HSD11B1 Regulation of Gene_expression of ADIPOQ 1 0.13 5.03 0
101 INT325283 Negative_regulation of MCL1 Positive_regulation of Gene_expression of ADIPOQ 1 0.14 1.53 0
102 INT301654 Binding of Slc27a2 and Slc27a5 1 0.15 0.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for fatty acid beta-oxidation. They are ordered first by their pain relevance and then by number of times they were reported in fatty acid beta-oxidation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
2 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
3 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
4 INT46054 Gene_expression of Decr1 39 0.65 12.82 9.48
5 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
6 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
7 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
8 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
9 INT11447 Positive_regulation of DECR1 9 0.67 3.12 4.94
10 INT49029 Positive_regulation of Decr1 19 0.09 6.28 3.98
11 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
12 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
13 INT84891 Gene_expression of PPARD 10 0.78 6.8 3.64
14 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58
15 INT53217 Positive_regulation of Gene_expression of Decr1 5 0.06 1.85 3.51
16 INT46055 Regulation of Gene_expression of Decr1 5 0.06 1.91 3.4
17 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
18 INT84890 Negative_regulation of PPARD 7 0.59 3.27 3.1
19 INT204340 Localization of ADIPOQ 20 0.75 25.18 2.64
20 INT26974 Negative_regulation of Adipoq 27 0.52 26.01 2.59
21 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47
22 INT9905 Gene_expression of DECR1 11 0.75 2.49 2.43
23 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26
24 INT135451 Positive_regulation of Positive_regulation of Adipoq 3 0.40 2.06 2.24
25 INT101516 Positive_regulation of PPARD 8 0.49 4.75 2.19
26 INT82310 Binding of HADHA 1 0.39 1.16 2.05
27 INT138029 Binding of Adipoq 10 0.40 6.81 2.04
28 INT134633 Localization of Adipoq 9 0.60 6.39 2.03
29 INT136860 Positive_regulation of Fabp3 5 0.60 4.53 1.99
30 INT227273 Localization of Adipoq 22 0.72 18.04 1.72
31 INT46052 Negative_regulation of Decr1 9 0.06 3.29 1.7
32 INT46053 Regulation of Decr1 4 0.08 0.69 1.56
33 INT84889 Positive_regulation of Gene_expression of PPARD 4 0.70 2.94 1.49
34 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47
35 INT112612 Gene_expression of Fabp3 14 0.59 6.35 1.47
36 INT84888 Binding of PPARD 5 0.48 2.82 1.45
37 INT82309 Positive_regulation of Binding of HADHA 1 0.35 0.87 1.38
38 INT227275 Negative_regulation of Gene_expression of Adipoq 19 0.53 19.51 1.15
39 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14
40 INT132972 Gene_expression of HADH 3 0.65 4.75 1.13
41 INT131318 Binding of Fabp3 4 0.35 3.33 1.05
42 INT160140 Regulation of Binding of Adipoq 1 0.37 0.87 0.92
43 INT82308 Negative_regulation of HADHA 2 0.38 1.52 0.91
44 INT16186 Negative_regulation of HADH 2 0.42 1.17 0.91
45 INT39281 Regulation of DECR1 3 0.44 0.14 0.89
46 INT153828 Phosphorylation of Fabp3 4 0.44 2.69 0.88
47 INT227270 Regulation of Gene_expression of Adipoq 5 0.55 7.35 0.85
48 INT84892 Negative_regulation of Gene_expression of PPARD 2 0.43 1.85 0.83
49 INT165684 Localization of HADH 3 0.73 0.91 0.82
50 INT151927 Regulation of Gene_expression of Adipoq 3 0.43 3.32 0.81
51 INT142013 Positive_regulation of Regulation of Adipoq 1 0.03 0.65 0.78
52 INT28020 Binding of Adipoq 10 0.36 11.49 0.77
53 INT338858 Regulation of HADHA 1 0.03 0.61 0.72
54 INT338863 Positive_regulation of HADHA 1 0.03 0.61 0.72
55 INT152564 Transcription of DECR1 1 0.52 0.34 0.7
56 INT148756 Regulation of Adipoq 10 0.60 7.83 0.67
57 INT301579 Gene_expression of Slc27a2 1 0.38 1.86 0.63
58 INT121076 Regulation of Fabp3 8 0.26 3.66 0.62
59 INT3491 Negative_regulation of CPT2 8 0.57 4.32 0.62
60 INT199099 Localization of Decr1 5 0.12 2.4 0.61
61 INT118310 Negative_regulation of Positive_regulation of Adipoq 2 0.34 2.47 0.61
62 INT179488 Positive_regulation of Transcription of Adipoq 3 0.37 0.5 0.6
63 INT53218 Negative_regulation of Positive_regulation of Decr1 2 0.03 0.54 0.58
64 INT73771 Regulation of EHHADH 1 0.44 0.94 0.58
65 INT227272 Transcription of Adipoq 8 0.64 8.29 0.49
66 INT83430 Positive_regulation of Binding of ADIPOQ 2 0.21 0.85 0.49
67 INT794 Negative_regulation of DECR1 4 0.57 1.61 0.48
68 INT101515 Negative_regulation of Positive_regulation of PPARD 2 0.35 0.68 0.47
69 INT84893 Negative_regulation of Binding of PPARD 1 0.43 0.5 0.46
70 INT83434 Negative_regulation of Binding of ADIPOQ 1 0.39 1.14 0.45
71 INT48910 Localization of DECR1 7 0.78 0.43 0.42
72 INT308980 Positive_regulation of Negative_regulation of Adipoq 3 0.33 2.3 0.4
73 INT301558 Positive_regulation of Gene_expression of Slc27a2 1 0.34 1.28 0.39
74 INT199083 Positive_regulation of Localization of Decr1 2 0.08 0.84 0.34
75 INT179491 Transcription of Adipoq 4 0.51 0.98 0.32
76 INT227268 Negative_regulation of Transcription of Adipoq 4 0.52 4.93 0.3
77 INT346132 Regulation of HADH 1 0.01 0.89 0.29
78 INT269026 Negative_regulation of Localization of Decr1 2 0.07 0.56 0.27
79 INT253941 Positive_regulation of Localization of Adipoq 5 0.24 2.59 0.21
80 INT150529 Positive_regulation of Negative_regulation of Adipoq 2 0.37 1.76 0.18
81 INT197872 Regulation of Regulation of Adipoq 3 0.35 1.11 0.17
82 INT28026 Positive_regulation of Binding of Adipoq 1 0.27 0 0.17
83 INT137455 Protein_catabolism of ADIPOQ 1 0.66 0.25 0.17
84 INT228162 Negative_regulation of Localization of Adipoq 1 0.38 1.29 0.17
85 INT301591 Positive_regulation of Slc27a2 1 0.34 1.44 0.17
86 INT308978 Negative_regulation of Regulation of Adipoq 1 0.28 0.92 0.17
87 INT263001 Regulation of Gene_expression of ADIPOQ 5 0.45 3.77 0.16
88 INT199066 Binding of Decr1 4 0.03 1.72 0.16
89 INT163262 Transcription of ADIPOQ 5 0.52 2.81 0.14
90 INT189792 Binding of EHHADH 1 0.36 0.79 0.14
91 INT262999 Negative_regulation of Gene_expression of ADIPOQ 7 0.43 9.52 0.12
92 INT186516 Regulation of PPARD 1 0.15 1.12 0.11
93 INT151191 Localization of Fabp3 2 0.32 0.99 0.09
94 INT157267 Negative_regulation of Localization of Adipoq 1 0.24 0.94 0.09
95 INT327816 Regulation of Positive_regulation of ADIPOQ 1 0.04 1.2 0.09
96 INT298827 Transcription of CPT1B 1 0.24 0.85 0.09
97 INT199063 Positive_regulation of Positive_regulation of Decr1 1 0.06 0.22 0.09
98 INT199081 Regulation of Positive_regulation of Decr1 1 0.06 0.28 0.08
99 INT127152 Negative_regulation of Acaa2 1 0.22 0.52 0.07
100 INT223571 Localization of PPARD 1 0.73 0.39 0.06
101 INT353069 Positive_regulation of Positive_regulation of ADIPOQ 1 0.13 1.75 0.05
102 INT245905 Negative_regulation of Transcription of ADIPOQ 1 0.42 1.26 0.05
103 INT59574 Positive_regulation of Gene_expression of DECR1 1 0.49 0.16 0.05
104 INT228584 Phosphorylation of Adipoq 1 0.38 0.61 0.04
105 INT321431 Negative_regulation of Positive_regulation of DECR1 1 0.03 0.77 0.04
106 INT251940 Positive_regulation of Transcription of ADIPOQ 1 0.01 0 0.04
107 INT336601 Negative_regulation of Binding of Decr1 1 0.03 0.69 0.04
108 INT199065 Negative_regulation of Gene_expression of Decr1 1 0.04 0.45 0.03
109 INT240621 Negative_regulation of Localization of ADIPOQ 1 0.39 0.64 0.03
110 INT200983 Transcription of EHHADH 1 0.01 0.17 0.03
111 INT336004 Positive_regulation of HADH 2 0.45 0.17 0
112 INT308158 Regulation of CPT1B 1 0.08 0.18 0
113 INT204358 Negative_regulation of Transcription of HADH 1 0.11 0.07 0
114 INT162317 Regulation of Gene_expression of DECR1 1 0.26 0.18 0
115 INT301585 Localization of Slc27a2 1 0.40 0.12 0
116 INT159743 Protein_catabolism of EHHADH 1 0.86 0.11 0
117 INT257464 Negative_regulation of Transcription of Adipoq 1 0.41 0.45 0
118 INT159742 Positive_regulation of EHHADH 1 0.49 0.12 0
119 INT336003 Binding of HADH 1 0.07 0.35 0
120 INT263530 Negative_regulation of Positive_regulation of ADIPOQ 1 0.31 1.43 0
121 INT312974 Gene_expression of CPT2 1 0.47 0.94 0
122 INT301571 Regulation of Slc27a2 1 0.13 0.22 0
123 INT179490 Negative_regulation of Gene_expression of Fabp3 1 0.37 0.26 0
124 INT308161 Negative_regulation of CPT1B 1 0.08 0.46 0
125 INT227262 Regulation of Transcription of Adipoq 1 0.35 0.47 0
126 INT162318 Regulation of Localization of DECR1 1 0.44 0.08 0
127 INT204362 Transcription of HADH 1 0.18 0.07 0
128 INT298825 Gene_expression of CPT1B 1 0.30 0.06 0
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