GO:0006642

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Name triglyceride mobilization
Categary Process
Go Slim No
Go Link GO:0006642
Unique Molecular Interactions 119
Total Molecular Interactions 160
Total Single Events 920
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for triglyceride mobilization. They are ordered first by their pain relevance and then by number of times they were reported for triglyceride mobilization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
2 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
3 INT333966 Binding of Il6r and Il6st 1 0.01 1.74 1.1
4 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
5 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97
6 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
7 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
8 INT328821 Binding of Il6st and Jak1 1 0.05 0 0.38
9 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
10 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
11 INT328824 Binding of Il6st and TYK2 1 0.02 0 0.38
12 INT297335 Binding of Apoc3 and Hdl1 1 0.00 0.92 0.29
13 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26
14 INT188200 IL6ST Positive_regulation of STAT3 1 0.25 0.38 0.23
15 INT258399 Binding of IL6R and IL6ST 1 0.06 0.61 0.18
16 INT128221 Binding of IL6ST and Il6 2 0.00 0.73 0.17
17 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
18 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17
19 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
20 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
21 INT329850 APOA5 Negative_regulation of Transcription of APOC3 1 0.24 0.85 0.15
22 INT308585 Binding of APOB and PLA2G7 1 0.07 0.69 0.09
23 INT289539 Negative_regulation of Sirt1 Negative_regulation of Gene_expression of Agrp 1 0.29 0.47 0.09
24 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
25 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
26 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08
27 INT289603 Sirt1 Negative_regulation of Localization of PPARG 1 0.02 0.43 0.08
28 INT283721 Binding of Lpin1 and Id2 1 0.38 0.18 0.08
29 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08
30 INT289540 Sirt1 Negative_regulation of Localization of Ins1 1 0.03 0.43 0.08
31 INT27376 Binding of IK and Slc27a5 1 0.22 0.07 0.07
32 INT289533 Sirt1 Negative_regulation of Pparg 1 0.18 0.42 0.07
33 INT256160 Positive_regulation of Binding of Pgc and Sirt1 1 0.55 0.21 0.07
34 INT289602 Sirt1 Negative_regulation of PPARG 1 0.02 0.37 0.07
35 INT256161 Binding of Pgc and Sirt1 1 0.38 0.21 0.07
36 INT340293 Binding of Ins1 and Sirt1 1 0.25 1.25 0.05
37 INT208353 Binding of Apoc4 and Apoc3 1 0.00 2.56 0.04
38 INT231395 Binding of HSD11B1 and Apob 1 0.27 1.18 0.04
39 INT325027 Apoc3 Negative_regulation of Pnlip 1 0.01 1.02 0.04
40 INT293899 UPF1 Positive_regulation of Gene_expression of APOB 1 0.01 0 0.04
41 INT240623 Binding of CRP and Apob 1 0.01 0.52 0.04
42 INT290180 Binding of APOB and PLTP 1 0.19 0.6 0.04
43 INT325026 Apoc3 Negative_regulation of Lpl 1 0.03 1.01 0.04
44 INT289541 Sirt1 Regulation of Gene_expression of Agrp 1 0.41 0.52 0.04
45 INT289538 Sirt1 Positive_regulation of Stat3 1 0.34 0.37 0.04
46 INT289542 Sirt1 Negative_regulation of Stat3 1 0.32 0.31 0.03
47 INT289526 Binding of Arc and Sirt1 1 0.08 0.55 0.03
48 INT194481 Binding of Apoe and Apob 1 0.07 0.51 0.03
49 INT194486 Binding of SNRNP70 and Apob 1 0.00 0.64 0.03
50 INT289599 Sirt1 Positive_regulation of Ppargc1a 1 0.51 0.36 0.03
51 INT180040 Binding of D7Cwr3P and Sirt1 1 0.00 0 0
52 INT332978 ACOX1 Negative_regulation of Transcription of Apoc3 1 0.00 0.98 0
53 INT247435 Binding of APOB and SNRNP70 1 0.04 2.2 0
54 INT353795 Binding of Cd320 and Apob 1 0.08 0.82 0
55 INT300696 Sirt1 Regulation of Cyb5r3 1 0.03 0 0
56 INT171598 Binding of APOB and Lipg 1 0.01 0.63 0
57 INT299444 Foxl2 Positive_regulation of Sirt1 1 0.24 0.31 0
58 INT247441 Binding of APOC3 and SNRNP70 1 0.04 0.26 0
59 INT289600 Negative_regulation of Binding of Sirt1 and Sirt1 1 0.47 1.17 0
60 INT299458 Gene_expression of Sirt1 Negative_regulation of Foxl2 1 0.25 0.32 0
61 INT283715 Lpin1 Regulation of 4930579C15Rik 1 0.35 0.74 0
62 INT353798 Binding of Hdl1 and Apob 1 0.01 0.82 0
63 INT204325 Binding of PPARGC1A and SIRT1 1 0.39 0.19 0
64 INT247444 Binding of APOA1 and APOC3 1 0.28 0.39 0
65 INT208349 Regulation of Binding of Apoc3 and Apoe 1 0.01 0.38 0
66 INT171599 Binding of APOC3 and Sst1 1 0.01 0.68 0
67 INT289534 Sirt1 Regulation of Regulation of Pomc 1 0.04 0.15 0
68 INT256165 Binding of Sirt6 and Sirt1 1 0.13 0.58 0
69 INT318218 SIRT1 Positive_regulation of Binding of FOXO3 1 0.44 0.51 0
70 INT289518 Arc Regulation of Sirt1 1 0.10 0.56 0
71 INT208365 Apoc3 Positive_regulation of Localization of PROC 1 0.00 1.13 0
72 INT298849 Binding of APOB and MCC 1 0.00 0.38 0
73 INT332962 Acaa1a Negative_regulation of Transcription of Apoc3 1 0.01 0.93 0
74 INT289537 Lep Negative_regulation of Sirt1 1 0.20 0.05 0
75 INT353802 Binding of APOE and Apob 1 0.05 0.83 0
76 INT210417 APOB Negative_regulation of CYP2D6 1 0.01 0 0
77 INT318219 SIRT1 Regulation of TBK1 1 0.03 0.43 0
78 INT208355 Binding of Apoc3 and Apoe 1 0.01 0.76 0
79 INT298856 Binding of APOB and MTG1 1 0.00 0.38 0
80 INT211570 Kit Regulation of Gene_expression of Lpin1 1 0.27 0.12 0
81 INT289517 Sirt1 Regulation of Prkag1 1 0.02 0.08 0
82 INT204326 SIRT1 Positive_regulation of PPARGC1A 1 0.51 0.19 0
83 INT318221 SIRT1 Positive_regulation of FOXO3 1 0.41 0.63 0
84 INT286444 PCSK9 Positive_regulation of Apob 1 0.02 0.49 0
85 INT277047 Binding of APOB and LDLR 1 0.25 0.82 0
86 INT337637 SIRT1 Negative_regulation of TP53 1 0.23 1.49 0
87 INT289598 Binding of Sirt1 and Sirt1 1 0.41 1.15 0
88 INT344723 Niacr1 Positive_regulation of Binding of APOB 1 0.31 1.05 0
89 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0
90 INT294316 IL6ST Positive_regulation of Gene_expression of IL11 1 0.22 0 0
91 INT247438 Binding of APOB and SACM1L 1 0.28 2 0
92 INT267974 APOB Negative_regulation of HSD11B1 1 0.01 0.75 0
93 INT300307 Binding of Tp53 and Sirt1 1 0.24 0.98 0
94 INT211577 Vldlr Regulation of Gene_expression of Lpin1 1 0.27 0.12 0
95 INT289519 Sirt1 Regulation of Rps6kb1 1 0.25 0.13 0
96 INT289530 Sirt1 Regulation of Foxo1 1 0.25 0.42 0
97 INT289523 Binding of Foxo1 and Positive_regulation of Sirt1 1 0.36 0.13 0
98 INT204321 NOS3 Regulation of SIRT1 1 0.23 0.1 0
99 INT314132 Sirt1 Positive_regulation of Ppargc1a 1 0.50 2.3 0
100 INT299451 Foxl2 Negative_regulation of Gene_expression of Sirt1 1 0.25 0.32 0
101 INT289531 Acsm3 Positive_regulation of Sirt1 1 0.01 0.27 0
102 INT171602 APOC3 Negative_regulation of Lipg 1 0.04 0.38 0
103 INT318216 SIRT1 Positive_regulation of Gene_expression of FOXO3 1 0.36 0.52 0
104 INT318217 SIRT1 Regulation of TP53 1 0.07 0.43 0
105 INT247440 Binding of APOA1 and APOB 1 0.28 1.02 0
106 INT352794 Binding of APOB and FGF21 1 0.01 1.98 0
107 INT298861 Binding of APOB and RAB7A 1 0.00 0.32 0
108 INT85010 Apo Regulation of Apob 1 0.00 0.14 0
109 INT204319 SIRT1 Regulation of Gene_expression of PPARGC1A 1 0.50 0.12 0
110 INT171603 APOC3 Negative_regulation of Lpl 1 0.48 0.38 0
111 INT289535 Negative_regulation of Sirt1 Negative_regulation of Binding of Foxo1 1 0.29 0.14 0
112 INT301654 Binding of Slc27a2 and Slc27a5 1 0.15 0.18 0
113 INT289529 Lep Regulation of Sirt1 1 0.28 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for triglyceride mobilization. They are ordered first by their pain relevance and then by number of times they were reported in triglyceride mobilization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
2 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
3 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
4 INT89986 Gene_expression of Il6st 5 0.56 2.35 3.15
5 INT172186 Gene_expression of IL6ST 20 0.75 11.63 2.67
6 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
7 INT190883 Gene_expression of Apoc3 16 0.38 14.18 1.93
8 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
9 INT9466 Binding of APOB 27 0.41 19.36 1.56
10 INT253403 Positive_regulation of Il6st 2 0.28 2.07 1.54
11 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
12 INT133422 Binding of IL6ST 10 0.40 4.9 1.49
13 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
14 INT159009 Regulation of Il6st 2 0.18 2 1.41
15 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
16 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36
17 INT96694 Negative_regulation of Slc27a5 1 0.53 0.96 1.3
18 INT20238 Regulation of APOB 9 0.61 11.52 1.26
19 INT75923 Positive_regulation of IL6ST 5 0.45 2.49 1.21
20 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
21 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
22 INT211548 Gene_expression of Lpin1 9 0.76 12.83 0.96
23 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9
24 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88
25 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85
26 INT10828 Regulation of Apob 7 0.39 7.55 0.83
27 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
28 INT51739 Negative_regulation of Apob 9 0.42 4.21 0.78
29 INT333965 Binding of Il6st 1 0.08 0.9 0.65
30 INT289580 Negative_regulation of Sirt1 23 0.58 9.03 0.48
31 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48
32 INT188230 Negative_regulation of IL6ST 3 0.33 0.49 0.45
33 INT300291 Phosphorylation of Sirt1 1 0.77 6.07 0.45
34 INT240935 Transcription of Sirt1 2 0.68 0.42 0.42
35 INT340290 Regulation of Transcription of Sirt1 1 0.43 0.13 0.42
36 INT335112 Regulation of Localization of APOC3 1 0.13 0.73 0.4
37 INT335117 Localization of APOC3 1 0.40 0.73 0.4
38 INT136518 Regulation of IL6ST 2 0.29 0.31 0.36
39 INT240914 Negative_regulation of Sirt1 9 0.46 3.16 0.34
40 INT339386 Negative_regulation of Gene_expression of Apob 3 0.43 1.91 0.34
41 INT289546 Negative_regulation of Gene_expression of Sirt1 5 0.42 3.1 0.31
42 INT83352 Positive_regulation of Negative_regulation of APOB 1 0.01 0.69 0.31
43 INT204368 Gene_expression of SIRT1 17 0.76 4.48 0.3
44 INT190878 Positive_regulation of Gene_expression of Apoc3 3 0.29 2.76 0.3
45 INT126195 Transcription of Il6st 1 0.39 0.2 0.28
46 INT194472 Positive_regulation of Gene_expression of Apob 2 0.15 1.71 0.22
47 INT283693 Transcription of Lpin1 1 0.67 1.31 0.22
48 INT171597 Gene_expression of APOC3 9 0.77 3.18 0.2
49 INT289551 Regulation of Sirt1 8 0.61 4.46 0.2
50 INT335113 Negative_regulation of Gene_expression of APOC3 1 0.24 0.34 0.2
51 INT203836 Negative_regulation of Negative_regulation of Apob 1 0.18 0.45 0.19
52 INT208335 Binding of Apoc3 3 0.01 2.11 0.18
53 INT190876 Negative_regulation of Apoc3 2 0.15 1.43 0.17
54 INT246620 Negative_regulation of Positive_regulation of Sirt1 2 0.39 1.9 0.17
55 INT155442 Negative_regulation of Slc27a5 1 0.42 0.22 0.17
56 INT62274 Negative_regulation of Gene_expression of APOB 4 0.32 5.9 0.16
57 INT277049 Regulation of Binding of APOB 1 0.27 0.91 0.16
58 INT171595 Negative_regulation of APOC3 3 0.43 1.99 0.15
59 INT171589 Transcription of APOC3 2 0.71 1.25 0.15
60 INT256111 Regulation of Gene_expression of Sirt1 1 0.32 0.73 0.14
61 INT204365 Positive_regulation of Gene_expression of SIRT1 8 0.68 2.9 0.13
62 INT203827 Localization of Apob 3 0.32 1.81 0.13
63 INT190877 Regulation of Gene_expression of Apoc3 2 0.11 2.09 0.13
64 INT240040 Protein_catabolism of Apob 1 0.01 1.79 0.13
65 INT240041 Negative_regulation of Protein_catabolism of Apob 1 0.01 1.8 0.13
66 INT136520 Positive_regulation of Regulation of IL6ST 1 0.09 0.08 0.13
67 INT194469 Positive_regulation of Apob 3 0.15 2.29 0.12
68 INT211536 Binding of Lpin1 2 0.46 1.06 0.12
69 INT289543 Regulation of Gene_expression of Sirt1 3 0.45 1.81 0.11
70 INT289547 Positive_regulation of Positive_regulation of Sirt1 2 0.69 0.76 0.11
71 INT332681 Regulation of Positive_regulation of Sirt1 1 0.16 0.69 0.11
72 INT208332 Positive_regulation of Apoc3 4 0.29 3.3 0.1
73 INT235511 Transcription of Apob 1 0.13 0.45 0.1
74 INT289567 Regulation of Negative_regulation of Sirt1 1 0.45 0.74 0.09
75 INT299517 Positive_regulation of Gene_expression of Il6st 1 0.06 0.23 0.09
76 INT213136 Binding of Apob 2 0.03 2.76 0.07
77 INT27375 Binding of Slc27a5 1 0.19 0.07 0.07
78 INT213138 Negative_regulation of Binding of Apob 1 0.03 0.86 0.07
79 INT213137 Positive_regulation of Binding of Apob 1 0.04 0.87 0.07
80 INT301544 Gene_expression of Slc27a5 1 0.58 0.5 0.07
81 INT289574 Negative_regulation of Positive_regulation of Sirt1 1 0.42 0.42 0.07
82 INT256136 Negative_regulation of Binding of Sirt1 1 0.30 0.5 0.07
83 INT283679 Positive_regulation of Lpin1 1 0.48 0.57 0.07
84 INT179763 Localization of Apob 6 0.66 4.72 0.06
85 INT239409 Transcription of APOB 3 0.65 1.86 0.06
86 INT206151 Positive_regulation of Gene_expression of IL6ST 2 0.24 0.35 0.06
87 INT235517 Positive_regulation of Positive_regulation of Apob 1 0.10 0.58 0.06
88 INT339991 Localization of SIRT1 1 0.34 0.3 0.06
89 INT183389 Regulation of Apob 4 0.01 5.17 0.05
90 INT255451 Positive_regulation of Positive_regulation of APOB 2 0.37 1.91 0.05
91 INT294329 Regulation of Gene_expression of IL6ST 1 0.22 0 0.05
92 INT253389 Positive_regulation of Positive_regulation of Il6st 1 0.28 0.07 0.05
93 INT256137 Positive_regulation of Regulation of Sirt1 1 0.36 0.32 0.05
94 INT283677 Localization of Lpin1 1 0.32 0.37 0.05
95 INT318236 Negative_regulation of Gene_expression of SIRT1 1 0.42 0.59 0.05
96 INT289587 Negative_regulation of Negative_regulation of Sirt1 1 0.42 0.65 0.05
97 INT256129 Negative_regulation of Gene_expression of Sirt1 1 0.31 0.4 0.05
98 INT239411 Localization of APOB 10 0.76 5.71 0.04
99 INT240615 Binding of Apob 2 0.07 0.85 0.04
100 INT211538 Negative_regulation of Lpin1 1 0.57 1.28 0.04
101 INT294344 Localization of IL6ST 1 0.39 0 0.04
102 INT246579 Negative_regulation of Localization of APOB 1 0.05 0.23 0.04
103 INT289584 Binding of Sirt1 3 0.48 1.35 0.03
104 INT270038 Positive_regulation of Positive_regulation of Sirt1 2 0.43 0.44 0.03
105 INT246622 Phosphorylation of Sirt1 2 0.74 0.56 0.03
106 INT325018 Regulation of Gene_expression of Apob 2 0.16 1.59 0.03
107 INT252743 Protein_catabolism of APOB 1 0.01 1.68 0.03
108 INT252758 Positive_regulation of Protein_catabolism of APOB 1 0.01 0.98 0.03
109 INT37798 Positive_regulation of Positive_regulation of Apob 1 0.06 1 0.03
110 INT204367 Positive_regulation of SIRT1 13 0.68 4.17 0
111 INT204349 Regulation of SIRT1 8 0.61 1.99 0
112 INT171594 Binding of APOC3 5 0.37 3.97 0
113 INT256134 Localization of Sirt1 5 0.50 2.99 0
114 INT204353 Transcription of SIRT1 3 0.68 0.67 0
115 INT179761 Negative_regulation of Localization of Apob 2 0.40 2.9 0
116 INT255450 Positive_regulation of Binding of APOB 1 0.37 2.88 0
117 INT229627 Negative_regulation of Negative_regulation of APOB 1 0.31 0.26 0
118 INT204361 Negative_regulation of SIRT1 1 0.42 0.18 0
119 INT289569 Transcription of Sirt1 1 0.71 0.25 0
120 INT171590 Regulation of Gene_expression of APOC3 1 0.61 0.41 0
121 INT241542 Regulation of Gene_expression of Apob 1 0.00 1.8 0
122 INT300686 Regulation of Binding of Sirt1 1 0.44 0.06 0
123 INT332950 Negative_regulation of Transcription of Apoc3 1 0.03 0.92 0
124 INT171592 Positive_regulation of APOC3 1 0.46 0.63 0
125 INT332957 Transcription of Apoc3 1 0.06 0.91 0
126 INT300287 Localization of Sirt1 1 0.66 1.46 0
127 INT301576 Binding of Slc27a5 1 0.28 0.06 0
128 INT317658 Positive_regulation of Gene_expression of Apob 1 0.17 1.59 0
129 INT289583 Regulation of Transcription of Sirt1 1 0.27 0.25 0
130 INT300683 Positive_regulation of Negative_regulation of Sirt1 1 0.45 0 0
131 INT211543 Regulation of Lpin1 1 0.60 0.28 0
132 INT204371 Positive_regulation of Transcription of SIRT1 1 0.49 0.13 0
133 INT318239 Regulation of Transcription of SIRT1 1 0.26 0.45 0
134 INT301522 Positive_regulation of Gene_expression of Slc27a5 1 0.38 0.46 0
135 INT240932 Negative_regulation of Transcription of Sirt1 1 0.34 0.29 0
136 INT289594 Regulation of Regulation of Sirt1 1 0.45 0.15 0
137 INT350520 Phosphorylation of SIRT1 1 0.25 0.72 0
138 INT204356 Regulation of Gene_expression of SIRT1 1 0.61 0.29 0
139 INT206153 Phosphorylation of IL6ST 1 0.22 0.05 0
140 INT332948 Negative_regulation of Gene_expression of Apoc3 1 0.05 0.93 0
141 INT206156 Positive_regulation of Phosphorylation of IL6ST 1 0.14 0.05 0
142 INT239410 Regulation of Localization of APOB 1 0.25 0.52 0
143 INT211562 Positive_regulation of Gene_expression of Lpin1 1 0.49 0.27 0
144 INT211545 Negative_regulation of Gene_expression of Lpin1 1 0.42 0.38 0
145 INT171596 Negative_regulation of Transcription of APOC3 1 0.58 0.42 0
146 INT306793 Negative_regulation of Positive_regulation of APOB 1 0.27 0.33 0
147 INT204331 Binding of SIRT1 1 0.47 0.39 0
148 INT171593 Positive_regulation of Gene_expression of APOC3 1 0.69 0.55 0
149 INT301547 Positive_regulation of Slc27a5 1 0.15 0.23 0
150 INT300685 Positive_regulation of Binding of Sirt1 1 0.67 0 0
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