GO:0006657

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Name CDP-choline pathway
Categary Process
Go Slim No
Go Link GO:0006657
Unique Molecular Interactions 75
Total Molecular Interactions 101
Total Single Events 1650
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for CDP-choline pathway. They are ordered first by their pain relevance and then by number of times they were reported for CDP-choline pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT161109 Avp Positive_regulation of Chkb 1 0.12 0.18 4.19
2 INT138961 Dbi Positive_regulation of Chkb 1 0.00 3.05 3.99
3 INT140014 Avp Negative_regulation of Chkb 1 0.04 1.58 2.86
4 INT43796 Binding of CDS1 and Adra2a 1 0.06 0 0.86
5 INT61165 Binding of Pag1 and Pcyt1a 1 0.01 0.33 0.73
6 INT189704 PRKCA Regulation of CHKB 1 0.13 0.18 0.66
7 INT226306 CHPT1 Positive_regulation of Localization of DBP 1 0.26 0.65 0.64
8 INT226308 CHPT1 Positive_regulation of Localization of SHBG 1 0.09 0.65 0.64
9 INT61164 Binding of Pomc and Pcyt1a 1 0.17 0.24 0.61
10 INT189689 CHKB Negative_regulation of Positive_regulation of PRKCA 1 0.11 0 0.4
11 INT132959 Binding of Chka and Trpv1 1 0.04 0 0.34
12 INT51088 Binding of CDS1 and PRMT1 1 0.06 0 0.28
13 INT189674 CHKB Negative_regulation of ASAP1 1 0.08 0 0.24
14 INT189693 CHKB Positive_regulation of PRKCA 1 0.11 0 0.24
15 INT189670 CHKB Negative_regulation of Gene_expression of DAG1 1 0.11 0 0.24
16 INT189700 CHKB Negative_regulation of PRKCA 1 0.11 0 0.24
17 INT188985 Binding of MKLN1 and CHPT1 1 0.06 0 0.19
18 INT189694 Negative_regulation of INSRR Negative_regulation of CHKB 1 0.00 0.07 0.15
19 INT189695 INSRR Negative_regulation of CHKB 1 0.00 0.07 0.15
20 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13
21 INT189702 CHKB Regulation of Gene_expression of TERT 1 0.06 0.55 0.1
22 INT89613 Binding of CHKB and FABP3 1 0.16 0.37 0.09
23 INT233858 CHKA Positive_regulation of Gene_expression of CDKN1B 1 0.10 0.17 0.09
24 INT211875 Binding of CDS1 and SMUG1 1 0.03 1.04 0.07
25 INT349886 Negative_regulation of Binding of Pcyt1a and Twist1 1 0.02 1.21 0.06
26 INT349887 Binding of Pcyt1a and Twist1 1 0.02 1.21 0.06
27 INT189677 CHKB Regulation of Transcription of TERT 1 0.10 1 0.05
28 INT294639 Bcl2a1a Positive_regulation of Gene_expression of Chkb 1 0.19 1.02 0.04
29 INT189665 CHKB Regulation of Gene_expression of CCND3 1 0.03 0.42 0.04
30 INT353204 TNNT1 Regulation of Chkb 1 0.08 0.19 0.04
31 INT260807 Binding of Chkb and Tnfsf10 1 0.14 0.85 0
32 INT165318 Binding of PSMD1 and CHPT1 1 0.23 0.57 0
33 INT225157 CDKN1A Regulation of CHKA 1 0.12 0.58 0
34 INT213390 Positive_regulation of Binding of CHKB and SELPLG 1 0.01 0.46 0
35 INT189678 Positive_regulation of CHKB Regulation of INSRR 1 0.00 0.06 0
36 INT285231 Binding of CHKB and TNNT1 1 0.15 0.05 0
37 INT189686 CHKB Regulation of Negative_regulation of INSRR 1 0.00 0.46 0
38 INT213391 Positive_regulation of Binding of CHKB and XPO1 1 0.04 0.46 0
39 INT226307 DBP Positive_regulation of Binding of CHPT1 1 0.26 0 0
40 INT271348 Binding of CHKB and MB 1 0.01 1.01 0
41 INT189683 CHKB Negative_regulation of Negative_regulation of INSRR 1 0.00 0.46 0
42 INT266068 Binding of CHKB and MUC16 1 0.22 0.74 0
43 INT189698 CHKB Regulation of TERT 1 0.06 0 0
44 INT102027 SLC43A3 Regulation of CHPT1 1 0.10 0.09 0
45 INT189682 CHKB Negative_regulation of Gene_expression of TERT 1 0.10 0.46 0
46 INT226305 SHBG Positive_regulation of Binding of CHPT1 1 0.09 0 0
47 INT189667 INSRR Regulation of CHKB 1 0.00 0.06 0
48 INT213393 Binding of CHKB and SELPLG 1 0.01 0.46 0
49 INT189706 CHKB Regulation of INSRR 1 0.00 0.06 0
50 INT213394 Binding of CHKB and XPO1 1 0.03 0.46 0
51 INT177762 GOPC Negative_regulation of Gene_expression of CHKB 1 0.11 0.08 0
52 INT189691 CHKB Negative_regulation of Positive_regulation of INSRR 1 0.00 0.07 0
53 INT285232 Binding of CHKB and LDHA 1 0.06 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for CDP-choline pathway. They are ordered first by their pain relevance and then by number of times they were reported in CDP-choline pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20260 Positive_regulation of Chkb 41 0.64 21.48 18.53
2 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92
3 INT20264 Gene_expression of Chkb 29 0.46 13.14 13.65
4 INT3074 Negative_regulation of Chkb 29 0.57 14 12.04
5 INT38255 Localization of Chkb 32 0.80 10.98 11.07
6 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03
7 INT93607 Binding of CHPT1 8 0.32 5.93 7.58
8 INT169435 Gene_expression of CHPT1 17 0.61 10.04 7.37
9 INT20673 Binding of CDS1 18 0.31 1.96 5.72
10 INT47662 Localization of CHKB 34 0.81 22.63 5.14
11 INT142488 Positive_regulation of Gene_expression of Chkb 7 0.23 4.09 4.54
12 INT33399 Negative_regulation of CDS1 12 0.37 1.97 4.22
13 INT38256 Negative_regulation of Localization of Chkb 10 0.56 3.58 4.11
14 INT20672 Gene_expression of CDS1 19 0.76 8.19 4.08
15 INT51841 Positive_regulation of CHPT1 13 0.43 6.82 3.62
16 INT38348 Positive_regulation of Localization of Chkb 9 0.64 2.75 3.37
17 INT66077 Regulation of CHPT1 12 0.38 6.1 3.23
18 INT9549 Regulation of CHKB 25 0.47 13.61 3.2
19 INT133354 Regulation of Chkb 9 0.60 4.35 3.15
20 INT36943 Binding of CHKB 14 0.37 4.09 2.75
21 INT133353 Negative_regulation of Negative_regulation of Chkb 2 0.42 1.31 2.41
22 INT20263 Gene_expression of Chka 5 0.06 0.8 2.37
23 INT238713 Positive_regulation of Gene_expression of CHPT1 3 0.43 2.7 1.97
24 INT20630 Positive_regulation of Gene_expression of CHKB 19 0.47 15.79 1.85
25 INT189003 Localization of CHPT1 8 0.64 4.75 1.82
26 INT33400 Regulation of CDS1 8 0.29 5.12 1.79
27 INT98096 Positive_regulation of CHKA 14 0.42 12.23 1.61
28 INT260795 Localization of Chkb 12 0.33 11.12 1.53
29 INT71515 Negative_regulation of CHPT1 6 0.38 2.28 1.51
30 INT29421 Positive_regulation of CDS1 7 0.46 3.16 1.47
31 INT16184 Negative_regulation of CHKB 20 0.53 10.61 1.42
32 INT18320 Positive_regulation of Chka 5 0.22 3.56 1.42
33 INT61163 Binding of Pcyt1a 1 0.16 0.57 1.32
34 INT188992 Positive_regulation of Localization of CHPT1 2 0.43 0.36 1.17
35 INT189748 Transcription of CHKB 6 0.36 1.6 1.07
36 INT186520 Gene_expression of CHKA 8 0.56 8.22 1
37 INT44201 Negative_regulation of Chka 4 0.58 0.88 1
38 INT110129 Regulation of Chka 1 0.61 0.35 0.98
39 INT153629 Negative_regulation of CHKA 3 0.12 2.33 0.92
40 INT20319 Negative_regulation of Gene_expression of Chkb 3 0.35 0.2 0.88
41 INT115362 Localization of Chka 2 0.45 0.71 0.78
42 INT205401 Gene_expression of Chkb 32 0.51 13.99 0.77
43 INT189764 Positive_regulation of Transcription of CHKB 1 0.24 0.61 0.75
44 INT189754 Negative_regulation of Transcription of CHKB 1 0.20 0.17 0.7
45 INT275877 Positive_regulation of Positive_regulation of Chkb 1 0.07 0.35 0.68
46 INT204075 Regulation of Gene_expression of CHKA 3 0.20 3.74 0.63
47 INT226309 Negative_regulation of Binding of CHPT1 3 0.36 1.47 0.6
48 INT133355 Regulation of Gene_expression of Chkb 1 0.07 0.21 0.6
49 INT189747 Regulation of Regulation of CHKB 1 0.22 0.28 0.6
50 INT347128 Negative_regulation of Positive_regulation of CHPT1 1 0.36 0.1 0.59
51 INT20626 Regulation of Gene_expression of CHKB 3 0.35 0.8 0.54
52 INT33401 Negative_regulation of Negative_regulation of CDS1 1 0.37 0 0.53
53 INT310569 Regulation of Localization of Chkb 3 0.09 1.49 0.49
54 INT275876 Binding of Chkb 1 0.04 0.54 0.46
55 INT328704 Negative_regulation of Localization of Chkb 1 0.10 3.84 0.44
56 INT18319 Transcription of Chka 1 0.04 0.09 0.43
57 INT189759 Regulation of Transcription of CHKB 1 0.22 0 0.41
58 INT130015 Positive_regulation of Localization of CHKB 3 0.48 1.72 0.39
59 INT189750 Negative_regulation of Positive_regulation of CHKB 4 0.26 2.36 0.38
60 INT142340 Positive_regulation of Chkb 3 0.47 6.44 0.38
61 INT320041 Negative_regulation of Gene_expression of CDS1 1 0.03 0.44 0.35
62 INT132957 Positive_regulation of Binding of Chka 1 0.05 0 0.34
63 INT132958 Binding of Chka 1 0.04 0 0.34
64 INT170626 Positive_regulation of Regulation of CHKB 3 0.38 1.22 0.31
65 INT37112 Negative_regulation of Binding of CDS1 1 0.37 0 0.31
66 INT186521 Regulation of CHKA 3 0.37 0.69 0.29
67 INT102114 Negative_regulation of Chkb 6 0.39 2.05 0.28
68 INT349882 Gene_expression of Pcyt1a 1 0.05 8.79 0.27
69 INT119928 Localization of CDS1 3 0.60 1.94 0.26
70 INT226310 Negative_regulation of Localization of CHPT1 1 0.27 2.83 0.24
71 INT349874 Positive_regulation of Gene_expression of Pcyt1a 1 0.04 3.54 0.22
72 INT279464 Regulation of Chkb 2 0.20 1.48 0.21
73 INT58857 Positive_regulation of Positive_regulation of CHKB 5 0.43 2.77 0.19
74 INT130020 Negative_regulation of Localization of CHKB 1 0.56 0.19 0.19
75 INT74158 Positive_regulation of Gene_expression of CDS1 2 0.43 1.05 0.15
76 INT115575 Regulation of Gene_expression of Pcyt1a 1 0.28 0 0.13
77 INT115576 Regulation of Pcyt1a 1 0.38 0 0.13
78 INT151422 Negative_regulation of Positive_regulation of Chkb 2 0.30 1.15 0.11
79 INT328701 Regulation of Localization of Chkb 1 0.07 1.22 0.1
80 INT292827 Positive_regulation of Pcyt1a 2 0.04 2.21 0.09
81 INT189001 Phosphorylation of CHPT1 1 0.58 0 0.09
82 INT188999 Positive_regulation of Phosphorylation of CHPT1 1 0.36 0 0.09
83 INT224235 Negative_regulation of Positive_regulation of CHKA 1 0.14 3.61 0.09
84 INT188990 Regulation of Gene_expression of CHPT1 2 0.32 0 0.08
85 INT46700 Negative_regulation of Pcyt1a 1 0.42 0.26 0.08
86 INT102115 Binding of Chkb 7 0.23 3.06 0.07
87 INT20623 Negative_regulation of Gene_expression of CHKB 6 0.45 0.57 0.07
88 INT115577 Gene_expression of Pcyt1a 3 0.42 0 0.07
89 INT20671 Regulation of Binding of CDS1 1 0.07 0 0.07
90 INT188996 Regulation of Localization of CHPT1 1 0.32 0.25 0.05
91 INT349877 Negative_regulation of Localization of Pcyt1a 1 0.03 1.09 0.05
92 INT349875 Positive_regulation of Localization of Pcyt1a 1 0.03 1.09 0.05
93 INT349878 Localization of Pcyt1a 1 0.05 1.09 0.05
94 INT260805 Regulation of Gene_expression of Chkb 3 0.32 0.95 0
95 INT295559 Negative_regulation of Gene_expression of Chkb 2 0.22 0.38 0
96 INT189765 Negative_regulation of Negative_regulation of CHKB 1 0.21 0 0
97 INT213404 Regulation of Positive_regulation of CHKB 1 0.08 0.25 0
98 INT233870 Positive_regulation of Gene_expression of CHKA 1 0.09 0.5 0
99 INT130016 Regulation of Localization of CHKB 1 0.43 0 0
100 INT186519 Localization of CHKA 1 0.67 3.57 0
101 INT292830 Transcription of Pcyt1a 1 0.03 0.5 0
102 INT336086 Positive_regulation of Regulation of Chkb 1 0.02 0.19 0
103 INT250724 Positive_regulation of Gene_expression of Chkb 1 0.33 0.32 0
104 INT201682 Protein_catabolism of CHKA 1 0.05 0.82 0
105 INT312285 Positive_regulation of Positive_regulation of Chkb 1 0.24 1.02 0
106 INT178656 Transcription of CHPT1 1 0.58 0.64 0
107 INT201684 Negative_regulation of Gene_expression of CHKA 1 0.03 0.33 0
108 INT267044 Negative_regulation of Gene_expression of Pcyt1a 1 0.03 0 0
109 INT251952 Negative_regulation of Localization of CDS1 1 0.28 0.44 0
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