GO:0006670

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Name sphingosine metabolic process
Categary Process
Go Slim No
Go Link GO:0006670
Unique Molecular Interactions 15
Total Molecular Interactions 20
Total Single Events 358
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sphingosine metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for sphingosine metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94
2 INT218848 Binding of Sgpp1 and Ppp1r9a 1 0.01 1.87 0.55
3 INT158621 Binding of SIGMAR1 and Sphk1 1 0.01 0 0.25
4 INT332481 ANXA1 Regulation of SGPP2 1 0.45 1.01 0.22
5 INT332485 SGPP2 Regulation of ANXA1 1 0.27 0.69 0.13
6 INT332480 OR2A5 Regulation of SGPP2 1 0.00 0.32 0.1
7 INT332489 Binding of JAM3 and SGPP2 1 0.27 0.24 0.04
8 INT332483 Binding of JAG1 and SGPP2 1 0.21 0.23 0.04
9 INT287676 Negative_regulation of Sphk1 Negative_regulation of Pik3r1 1 0.14 0.42 0
10 INT287673 Negative_regulation of Sphk1 Negative_regulation of Akt1 1 0.20 0.42 0
11 INT171404 ISYNA1 Positive_regulation of Negative_regulation of Ppap2a 1 0.05 0.23 0
12 INT332487 ANXA1 Regulation of Gene_expression of SGPP2 1 0.45 0.08 0
13 INT335526 SPHK1 Regulation of Gene_expression of SGCB 1 0.27 0.86 0
14 INT335525 Binding of SGCB and SPHK1 1 0.22 1.61 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for sphingosine metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in sphingosine metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254145 Gene_expression of Ppap2a 9 0.10 2.66 4.33
2 INT17879 Positive_regulation of Ppap2a 17 0.53 9.72 3.8
3 INT138437 Gene_expression of Sphk1 23 0.65 10.01 2.61
4 INT258166 Phosphorylation of Ppap2a 1 0.10 0.97 2.1
5 INT53500 Negative_regulation of Ppap2a 11 0.45 3.31 1.92
6 INT258162 Positive_regulation of Gene_expression of Ppap2a 3 0.09 1.4 1.88
7 INT138439 Positive_regulation of Gene_expression of Sphk1 14 0.48 5.93 1.86
8 INT154816 Negative_regulation of Sphk1 19 0.41 11.38 1.84
9 INT163535 Negative_regulation of Sgpp1 6 0.13 3.35 1.52
10 INT138434 Positive_regulation of Sphk1 10 0.48 2.18 1.18
11 INT254146 Localization of Ppap2a 2 0.11 0.39 1.01
12 INT24372 Negative_regulation of Sphk1 1 0.59 0 0.85
13 INT258161 Negative_regulation of Negative_regulation of Ppap2a 1 0.05 0.35 0.75
14 INT24373 Gene_expression of Sphk1 3 0.67 0 0.68
15 INT332498 Positive_regulation of SGPP2 1 0.44 1.21 0.55
16 INT24375 Regulation of Sphk1 1 0.62 0 0.5
17 INT24371 Positive_regulation of Sphk1 2 0.41 2.37 0.46
18 INT163534 Phosphorylation of Sgpp1 1 0.18 0.17 0.45
19 INT163537 Negative_regulation of Phosphorylation of Sgpp1 1 0.10 0.17 0.45
20 INT177684 Binding of Ppap2a 5 0.05 0.16 0.43
21 INT332520 Gene_expression of SGPP2 1 0.74 0.79 0.37
22 INT332502 Positive_regulation of Gene_expression of SGPP2 1 0.48 0.55 0.37
23 INT53502 Regulation of Ppap2a 6 0.34 1.42 0.32
24 INT24374 Regulation of Gene_expression of Sphk1 1 0.45 0 0.31
25 INT53501 Negative_regulation of Positive_regulation of Ppap2a 1 0.01 0.7 0.29
26 INT191666 Positive_regulation of Sgpp1 1 0.01 1.8 0.26
27 INT302791 Negative_regulation of Gene_expression of Sphk1 1 0.23 0.34 0.24
28 INT280593 Negative_regulation of Gene_expression of SPHK1 2 0.43 3.92 0.19
29 INT280594 Gene_expression of SPHK1 2 0.78 71.47 0.19
30 INT332500 Regulation of SGPP2 1 0.43 0.8 0.18
31 INT287672 Positive_regulation of Positive_regulation of Sphk1 1 0.48 0.38 0.14
32 INT280581 Regulation of SPHK1 2 0.45 1.33 0.13
33 INT280589 Localization of SPHK1 2 0.75 2.61 0.13
34 INT158618 Binding of Sphk1 1 0.01 0 0.13
35 INT345097 Protein_catabolism of Ppap2a 1 0.08 0.69 0.11
36 INT287665 Regulation of Negative_regulation of Sphk1 1 0.43 0.11 0.1
37 INT171402 Positive_regulation of Positive_regulation of Ppap2a 4 0.36 0.81 0.04
38 INT332499 Negative_regulation of Gene_expression of SGPP2 1 0.56 0 0
39 INT287663 Localization of Sphk1 1 0.72 0.84 0
40 INT335530 Positive_regulation of Gene_expression of SPHK1 1 0.69 21.31 0
41 INT335533 Negative_regulation of SPHK1 1 0.59 2.38 0
42 INT335531 Phosphorylation of SPHK1 1 0.81 1 0
43 INT177685 Regulation of Binding of Ppap2a 1 0.04 0.1 0
44 INT335529 Transcription of SPHK1 1 0.53 0.74 0
45 INT207893 Gene_expression of Sgpp1 1 0.03 1.36 0
46 INT207895 Positive_regulation of Gene_expression of Sgpp1 1 0.02 1.47 0
47 INT335539 Regulation of Gene_expression of SPHK1 1 0.62 4.55 0
48 INT287668 Regulation of Sphk1 1 0.43 0.66 0
49 INT287664 Binding of Sphk1 1 0.36 0.97 0
50 INT335535 Positive_regulation of SPHK1 1 0.69 12.71 0
51 INT287661 Regulation of Positive_regulation of Sphk1 1 0.43 0 0
52 INT207889 Regulation of Gene_expression of Sgpp1 1 0.02 1.36 0
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