GO:0006686

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Name sphingomyelin biosynthetic process
Categary Process
Go Slim No
Go Link GO:0006686
Unique Molecular Interactions 21
Total Molecular Interactions 27
Total Single Events 153
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sphingomyelin biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for sphingomyelin biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT110835 Binding of SPTLC2 and SPTLC1 2 0.42 1.36 0.68
2 INT120870 Binding of Wnk1 and Sptlc1 1 0.14 1.24 0.56
3 INT110834 Binding of AGXT and SPTLC2 2 0.27 0.71 0.36
4 INT329410 Binding of SPTLC1 and Spt 1 0.04 1 0.35
5 INT229785 Binding of RAB7A and SPTLC1 1 0.40 1.5 0.27
6 INT234831 Binding of SPTLC1 and Abo 1 0.00 1.61 0.23
7 INT329409 Binding of SPTLC1 and Dstn 1 0.05 1.3 0.23
8 INT157212 Binding of SPTLC1 and WNK1 1 0.07 0.67 0.22
9 INT157216 Binding of SPTLC2 and WNK1 1 0.03 0.68 0.22
10 INT157214 Binding of SGCG and SPTLC2 1 0.14 0.68 0.22
11 INT157215 Binding of SGCG and SPTLC1 1 0.32 0.67 0.22
12 INT260070 Binding of PHF2 and SPTLC1 1 0.17 1.93 0.1
13 INT122927 Ntrk1 Positive_regulation of SPTLC1 1 0.00 0.65 0.09
14 INT314266 SUPT4H1 Positive_regulation of SPTLC1 1 0.02 0.13 0.03
15 INT352753 Sgms1 Regulation of Localization of Prkd1 1 0.23 0 0
16 INT295617 UBXN11 Negative_regulation of SPTLC1 1 0.03 0.57 0
17 INT110836 Binding of AGXT and SPTLC1 1 0.30 0.11 0
18 INT352761 SGMS2 Regulation of Localization of Prkd1 1 0.20 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for sphingomyelin biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in sphingomyelin biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71
2 INT229788 Negative_regulation of SPTLC1 1 0.38 4.82 3.53
3 INT81955 Positive_regulation of SPTLC1 12 0.70 10.25 3.12
4 INT72870 Negative_regulation of SPTLC2 7 0.57 1.82 1.73
5 INT229793 Negative_regulation of Positive_regulation of SPTLC1 1 0.43 1.49 1.17
6 INT80338 Gene_expression of SPTLC1 10 0.78 4.06 1.09
7 INT66043 Regulation of SPTLC2 3 0.44 1.62 1.09
8 INT229786 Transcription of SPTLC1 1 0.60 0.78 0.71
9 INT66042 Positive_regulation of SPTLC2 2 0.68 0.97 0.66
10 INT80335 Localization of SPTLC1 4 0.75 0.61 0.65
11 INT94146 Regulation of SPTLC1 2 0.51 2.39 0.36
12 INT110837 Binding of SPTLC2 1 0.36 0.7 0.35
13 INT132294 Positive_regulation of Sptlc1 3 0.31 3.84 0.14
14 INT352739 Negative_regulation of SGMS2 1 0.35 0.94 0.13
15 INT352725 Negative_regulation of Sgms1 1 0.41 0.64 0.12
16 INT294749 Gene_expression of Sgms1 3 0.54 0.5 0.05
17 INT242691 Transcription of SPTLC2 1 0.01 0 0.05
18 INT295510 Negative_regulation of Sptlc1 4 0.11 2.11 0
19 INT352717 Negative_regulation of Negative_regulation of Sgms1 1 0.30 0.07 0
20 INT352736 Regulation of Gene_expression of SGMS2 1 0.27 0.07 0
21 INT352730 Regulation of Gene_expression of Sgms1 1 0.31 0.07 0
22 INT352720 Positive_regulation of Gene_expression of Sgms1 1 0.35 0.09 0
23 INT352741 Gene_expression of SGMS2 1 0.47 0.16 0
24 INT352746 Negative_regulation of Regulation of SGMS2 1 0.26 0.06 0
25 INT352719 Negative_regulation of Regulation of Sgms1 1 0.30 0.06 0
26 INT352743 Regulation of SGMS2 1 0.37 0.22 0
27 INT81956 Positive_regulation of Protein_catabolism of SPTLC1 1 0.06 0.16 0
28 INT352714 Regulation of Sgms1 1 0.31 0.21 0
29 INT81957 Protein_catabolism of SPTLC1 1 0.10 0.15 0
30 INT352745 Positive_regulation of Gene_expression of SGMS2 1 0.42 0.09 0
31 INT352718 Regulation of Negative_regulation of Sgms1 1 0.31 0 0
32 INT352744 Regulation of Negative_regulation of SGMS2 1 0.27 0 0
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