GO:0006690

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Name icosanoid metabolic process
Categary Process
Go Slim No
Go Link GO:0006690
Unique Molecular Interactions 26
Total Molecular Interactions 30
Total Single Events 214
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for icosanoid metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for icosanoid metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT172144 IL4 Negative_regulation of Transcription of PLA2G4A 1 0.02 0.82 0.58
2 INT248146 PLA2G6 Negative_regulation of Phosphorylation of PLA2G4A 1 0.07 0.72 0.4
3 INT301666 Binding of CYP4F2 and Ltb4r1 1 0.02 0.57 0.28
4 INT142450 B4GALNT1 Regulation of Gene_expression of PTGIS 1 0.02 0.24 0.27
5 INT301670 Binding of CYP4F2 and Cyp4f18 1 0.02 1.04 0.27
6 INT142447 PTGS2 Regulation of Gene_expression of PTGIS 1 0.30 0.24 0.27
7 INT96402 Binding of PTGS2 and TBXAS1 1 0.02 0.32 0.26
8 INT142446 Regulation of CPOX Regulation of Gene_expression of PTGIS 1 0.10 0.26 0.22
9 INT142448 TNF Positive_regulation of Localization of PTGIS 1 0.35 0.28 0.21
10 INT179689 Binding of CYP4F3 and DAK 1 0.00 1.23 0.2
11 INT146744 Binding of NR3C1 and PLA2G4A 1 0.26 0.25 0.15
12 INT89597 Binding of CPOX and TBXAS1 1 0.04 0.05 0.14
13 INT146743 Positive_regulation of Binding of GSR and PLA2G4A 1 0.40 0.14 0.11
14 INT146742 Binding of GSR and PLA2G4A 1 0.28 0.14 0.11
15 INT234606 Tlr4 Positive_regulation of Transcription of PLA2G4A 1 0.57 0 0.06
16 INT301496 PPA1 Negative_regulation of CYP4F3 1 0.01 0.69 0.05
17 INT301497 UBXN11 Negative_regulation of CYP4F3 1 0.37 0.69 0.05
18 INT249199 CA2 Positive_regulation of PLA2G4A 1 0.15 0 0.04
19 INT348362 Binding of C2 and Positive_regulation of Localization of PLA2G4A 1 0.02 0.37 0.03
20 INT268096 Binding of CYP4F3 and PDSS1 1 0.00 0.35 0
21 INT249179 PLA2G4A Regulation of CYBB 1 0.18 0 0
22 INT281907 VEGFA Positive_regulation of Gene_expression of PTGIS 1 0.03 0.14 0
23 INT268093 Binding of FAS and CYP4F3 1 0.01 0.35 0
24 INT281904 ANG Positive_regulation of PTGIS 1 0.04 0 0
25 INT249191 CYBB Positive_regulation of PLA2G4A 1 0.20 0 0
26 INT249187 Binding of CYBB and PLA2G4A 1 0.14 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for icosanoid metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in icosanoid metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64864 Gene_expression of PLA2G4A 18 0.77 10.45 4.09
2 INT6956 Gene_expression of PTGIS 29 0.76 12.1 3.8
3 INT179101 Gene_expression of CYP4F3 14 0.65 6.89 1.98
4 INT91773 Positive_regulation of PLA2G4A 10 0.50 4.4 1.54
5 INT91764 Positive_regulation of Gene_expression of PLA2G4A 8 0.69 5.43 1.52
6 INT179695 Negative_regulation of CYP4F3 4 0.45 4.94 1.38
7 INT169363 Negative_regulation of PTGIS 4 0.20 3.35 1.22
8 INT10033 Localization of PTGIS 10 0.69 6.8 1.07
9 INT64863 Localization of PLA2G4A 9 0.44 3.33 1.07
10 INT65166 Negative_regulation of PLA2G4A 7 0.57 1.55 0.96
11 INT179698 Positive_regulation of CYP4F3 5 0.54 3.86 0.91
12 INT179697 Regulation of CYP4F3 4 0.47 4.36 0.83
13 INT89599 Binding of TBXAS1 3 0.23 0.41 0.83
14 INT146746 Transcription of PLA2G4A 3 0.69 1.03 0.8
15 INT50501 Negative_regulation of TBXAS1 3 0.30 1.26 0.74
16 INT127988 Gene_expression of TBXAS1 2 0.38 0.22 0.66
17 INT78775 Regulation of PLA2G4A 4 0.25 1.45 0.55
18 INT142452 Regulation of Gene_expression of PTGIS 3 0.23 0.72 0.53
19 INT76858 Binding of PLA2G4A 4 0.30 1.22 0.52
20 INT296837 Negative_regulation of Gene_expression of PTGIS 2 0.17 1.11 0.52
21 INT179102 Binding of CYP4F3 4 0.29 1.75 0.41
22 INT248153 Phosphorylation of PLA2G4A 1 0.20 0.65 0.38
23 INT146747 Negative_regulation of Gene_expression of PLA2G4A 1 0.43 0.66 0.33
24 INT301603 Negative_regulation of Gene_expression of CYP4F3 1 0.33 0.66 0.32
25 INT6955 Positive_regulation of Gene_expression of PTGIS 3 0.36 0.6 0.29
26 INT301606 Binding of CYP4F2 1 0.25 0.51 0.29
27 INT10034 Positive_regulation of Localization of PTGIS 1 0.31 1.38 0.26
28 INT142451 Negative_regulation of Localization of PTGIS 2 0.50 2 0.22
29 INT141874 Binding of PTGIS 1 0.36 1.06 0.22
30 INT301598 Gene_expression of CYP4F2 1 0.41 0.36 0.18
31 INT146748 Positive_regulation of Transcription of PLA2G4A 1 0.50 0.22 0.17
32 INT301600 Positive_regulation of CYP4F2 1 0.47 0.28 0.13
33 INT10031 Positive_regulation of PTGIS 2 0.31 0.67 0.12
34 INT301605 Transcription of CYP4F3 1 0.53 0.19 0.1
35 INT301610 Negative_regulation of CYP4F2 1 0.39 0.83 0.08
36 INT172663 Regulation of PTGIS 1 0.00 0.27 0.05
37 INT172665 Regulation of TBXAS1 1 0.01 0.13 0.05
38 INT224811 Negative_regulation of Localization of CYP4F3 1 0.02 0.9 0.04
39 INT224810 Localization of CYP4F3 1 0.04 0.85 0.04
40 INT249275 Positive_regulation of Localization of PLA2G4A 1 0.25 0 0.04
41 INT281929 Transcription of PTGIS 1 0.07 0.34 0.03
42 INT143410 Regulation of Localization of PLA2G4A 2 0.34 0 0
43 INT355750 Positive_regulation of Gene_expression of CYP4F3 1 0.49 0 0
44 INT231647 Localization of TBXAS1 1 0.46 0 0
45 INT301611 Regulation of Gene_expression of CYP4F3 1 0.21 0.15 0
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